Books

Summary: This Open access book offers updated and revised information on vessel health and preservation (VHP), a model concept first published in poster form in 2008 and in JVA in 2012, which has received a great deal of attention, especially in the US, UK and Australia. The book presents a model and a new way of thinking applied to vascular access and administration of intravenous treatment, and shows how establishing and maintaining a route of access to the bloodstream is essential for patients in acute care today. Until now, little thought has been given to an intentional process to guide selection, insertion and management of vascular access devices (VADs) and by default actions are based on crisis management when a quickly selected VAD fails. The book details how VHP establishes a framework or pathway model for each step of the patient experience, intentionally guiding, improving and eliminating risk when possible. The evidence points to the fact that reducing fragmentation, establishing a pathway, and teaching the process to all stakeholders reduces complications with intravenous therapy, improves efficiency and diminishes cost. As such this book appeals to bedside nurses, physicians and other health professionals.

Contents:
Preface. About the concept of VHP, beginnings, process and ideal
Section 1. Right Assessment and Right Vein
Chapter 1. Catheter and vein selection with avoidance of joints and danger zones
Chapter 2. Ultrasonic assessment and placement of right device
Section 2. Right Training
Chapter 3. Training process, competencies, preparation for PIV, PICC, CVC insertions
Section 3. Right Insertion
Chapter 4. Catheter size, type, number of lumen for patient and treatment
Chapter 5. Placement with no more than 2 attempts
Chapter 6. Infection Prevention principles with Kits for insertion and compliance with sterile procedure (bundles, checklist, CHG, etc)
Chapter 7. Tip positioning
Chapter 8. Securement
Section 4. Pediatric Vessel Health
Chapter 9. Differences between paediatrics and adults for vein assessment
Chapter 10. Right Site selection
Chapter 11. Right Device assessment (type, size, no. of lumens)
Chapter 12. Right Technology assessment
Chapter 13. Why is VHP important in paediatrics?
Chapter 14. Troubleshooting in paediatrics
Section 5. Right Supplies and Technology
Chapter 15. Ultrasound
Chapter 16. Insertion kits for USGPIV, PICC, Midline, CVC
Chapter 17. Antimicrobial dressings
Chapter 18. Needleless connector issues
Section 6. Right Care and Assessment
Chapter 19. Daily or twice daily assessment for catheter function, dressing adherence and necessity of device
Chapter 20. Hub disinfection issues and compliance measures
Chapter 21. Flushing with proper techniques
Section 7. Right Evaluation
Chapter 22. How to evaluate a VHP program initiative
Chapter 23. Staff education and satisfaction
Chapter 24. Patient satisfaction
Chapter 25. Pathway effectiveness and outcome measures.

Contents:
Assessment of the vestibular system: history and physical examination / Welgampola, M.S.; Bradshaw, A.P.; Halmagyi, G.M
Imaging of temporal bones / Pyykke, I.; Zou, J.; Gürkov, R.; Naganawa, S.; Nakashima, T
Videonystagmography and posturography / Falls, C
Vestibular testing-rotary chair and dynamic visual acuity tests / Gimmon, Y.; Schubert, M.C
Otolith function testing / Taylor, R.L.; Welgampola, M.S
Video head impulse testing: brevity is the soul of hit / Welgampola, M.C.; Taylor, R.L.; Halmagyi, G.M
Benign paroxysmal positional vertigo / Instrum, R.S.; Parnes, L.S
Meniere's disease / Gibson, W.P.R
Vestibular neuritis : recent advances in etiology, diagnostic evaluation, and treatment / Le, T.N.; Westerberg, B.; Lea, J
Perilymphatic fistulas and superior semi-circular canal dehiscence syndrome / Weinreich, H.M.; Carey, J.P
Aminoglycoside vestibulotoxicity / Rutka, J
Post-traumatic dizziness: clinical and medicolegal aspects / Westerberg, B.D.; Lea, J.; Cameron, A.F
Migraine associated vertigo / Hain, T.; Cherchi, M
An overview of central vertigo disorders / Ranalli, P
Special considerations for the pediatric patient / Cushing, S.L.; Papsin, B.C
The aging vestibular system : dizziness and imbalance in the elderly / Jahn, K
Systemic disease considerations in the management of the dizzy patient / Rea, P.A.; Ronan, N
Advances in vestibular rehabilitation / Sulway, S.; Whitney, S.L
Psychiatric considerations in the management of dizzy patients / Staab, J.P.

Summary: Vestibular Migraine is a concise monograph that presents the scientific basis for the diagnosis and treatment of this common yet largely unrecognized cause of dizziness. Current knowledge of the features of the disorder is described, and clear guidance is provided on the differentiation of vestibular migraine from other conditions that induce dizziness, including M©♭ni©·reℓ́ℓs disease. Symptomatic treatment and the various prophylactic options are discussed and evaluated, and advice is also included on long-term treatment and the circumstances under which treatment should be discontinued. Approximately one-third of migraineurs experience dizziness that sometimes occurs in conjunction with the headaches but often arises separately. The vestibular symptoms in this population vary in frequency, severity, and duration; they are described as spinning or lightheadedness or both and are often exacerbated by position change. Ear fullness, tinnitus, and hearing loss are frequent complaints. Vestibular migraine is diagnosed by carefully obtaining a history: there are no pathognomonic blood, urine, or imaging studies. This book will be of interest to all physicians and other health care providers who deal with dizzy patients, including internists, family physicians, neurologists, otolaryngologists, and trainees in those specialties, as well as nurse practitioners and physician assistants.

Contents:
Introduction
Diagnosis of migraine headaches
Diagnosis of vestibular migraine
Vestibular migraine and Meniere?s disease
Treatment-Joel Goebel.

Summary: This book provides a multidisciplinary approach to vestibular migraine and related syndromes in which dizziness is the most predominant feature. Starting from the neurological point of view, the pathophysiology, classification, neurophysiology, and therapy of migraine are discussed. Readers will learn how to recognize and properly treat vestibular migraine, which is often undiagnosed or misdiagnosed as Ménière's syndrome (a form of vertigo characterized by vertigo spells and hearing loss that presents comorbidity with migraine) or benign paroxysmal positional vertigo (in which patients experience brief episodes of vertigo, lasting from seconds to 1 minute, when they move their heads in a certain way). The described diagnostic and therapeutic strategies include the newest, state of the art approaches. Further aspects of migraine that are considered include hyperexcitability in the brain and the triad of migraine, dizziness, and anxiety. In addition, the imaging of migraine, and of vestibular migraine in particular, is discussed and clinical records are reported. Vestibular Migraine and Related Syndromes is based on the practical and clinical experiences of an authoritative group of well-known neurologists, ENT specialists, and neuro-otologists. It provides neurologists with a complete overview of relevant clinical features, otolaryngologists with clear descriptions of clinical aspects and the pathophysiology of migraine, and radiologists with guidance on the role of imaging techniques.

Contents:
Foreword
Migraine: Pathophysiology and Classification
Neurophysiology of Migraine
Therapy of Migraine
Migraine: the Hypersensitive Brain
Epidemiology of Vestibular Migraine and Related Syndromes
Vestibular migraine: Classification and Clinical Features
Vestibular Migraine: Vestibular Testing and Pathophysiology
Visual Vertigo and Motion Sickness
Therapy of Vestibular Migraine
Vertigo as a Migraine Precursor
Menière's Syndrome and Migraine
Benign Paroxysmal Positional Vertigo and Migraine
Dizziness Anxiety and Migraine
Dizziness and Cognitive Processes
Imaging of Migraine and Vestibular Migraine.

Summary: This video guide increases the surgeon's understanding of all types of surgical approaches for vestibular schwannoma surgery: retrosigmoid, translabyrinthine, middle cranial fossa and combined approaches. 2D and 3D videos are included to increase the readers' understanding of these complex surgical techniques. These are accompanied by step-by-step narrated cadaveric dissection videos showing the crucial steps of each approach. This book is a learning tool and video reference for those training to perform the procedure and enhances the readers understanding of neuroanatomy. A detailed review of all surgical options and their risks, along with tips, tenets and pitfalls is included. The authors provide an unbiased discussion of all options with balanced comparison between surgical approaches and algorithms for patient selection.

Contents:
Acoustic neuromas: general considerations
Vestibular schwannomas: neurology, neurophysiology and anatomy
Middle fossa approach to Vestibular schwannomas
Retrosigmoid approach for vestibular schwannomas surgery
Translabyrinthine approach to vestibular schwannomas
Complex vestibular schwannomas: case illustrations of surgical technique.

Summary: This volume explores the unique psychiatric needs of active and former military personnel and offers clinical pearls for the optimal delivery of care for these individuals. Written by experts in military and veteran psychiatry, this book addresses the most common issues in military and veteran patients, including depression, traumatic brain injury, posttraumatic stress disorder, substance use disorder, homelessness, and suicidality. Chapters highlight the characteristics of veterans suffering from each disorder that requires special treatment, making it a valuable resource for both military and civilian clinicians. Veteran Psychiatry in the US is a valuable resource for all mental health clinicians working with or seeking to work with veterans, including psychiatrists, neurologists, primary care physicians, psychologists, counselors, social workers, nurses, residents, and all others.

Summary: This richly illustrated two-volume book offers a comprehensive and essential reference guide for veterinary pathologists and clinical veterinarians interested in performing animal necropsies for forensic casework. It presents a broad range of animal crime cases, with particular focus on the post mortem examination and the observed pathology. This first volume introduces readers to veterinary forensics and the role of the veterinary pathologist in animal crime investigations. It guides them through the process of evidence collection and documentation, and covers the fundamentals of forensic necropsy and the estimation of time since death. In-depth descriptions of how to conduct the forensic evaluation of various traumatic injuries, firearm injuries, and asphyxia are also provided.

Contents:
Medicolegal investigation / Rachel Touroo, Jason W. Brooks, Randall Lockwood, and Robert Reisman
Crime scene findings and the identification, collection, and preservation of evidence / Rachel Touroo and Amanda Fitch
Performing the forensic necropsy / Rebecca Kagan and Jason W. Brooks
Postmortem changes and estimating the postmortem interval / Jason W. Brooks and Lerah Sutton
Blunt force trauma / Robert Reisman
Sharp force trauma / Martha Smith-Blackmore and Nicholas Robinson
Firearm injuries / N. Bradley-Siemens, A.I. Brower, and R. Kagan
Strangulation, suffocation, and asphyxia / Beverly J. McEwen.

Summary: This richly illustrated two-volume book offers a comprehensive and essential reference guide for veterinary pathologists and clinical veterinarians interested in performing animal necropsies for forensic casework. It presents a broad range of animal crime cases, with particular focus on the post mortem examination and the observed pathology. This second volume guides readers through the forensic evaluation of animal deaths caused by drowning, fire, electrical, and environmental injuries, poisoning, animal fighting, neglect, and sexual abuse. In addition, it offers practical advice on evaluating anesthesia-related deaths, age estimation, and how to write the necropsy report.

Contents:
Drowning and bodies recovered from water / Beverly J. McEwen and Jodie A. Gerdin
Thermal/electrical injuries / Tabitha C. Viner
Neglect / N. Bradley-Siemens, A.I. Brower, and R. Reisman
Environmental injuries / Doris M. Miller
Poisoning / Lisa A. Murphy and Rebecca Kagan
Anesthesia-related deaths / Josepha DeLay
Animal fighting / Rachel Touroo and Robert Reisman
Animal sexual abuse investigations / Adam W. Stern
Ritualistic animal killing / Sean P. McDonough and Brian Holoyda
Writing the necropsy report / Gregory J. Davis and Sean P. McDonough
Age determination in dogs and cats / Lerah K. Sutton, Jason H. Byrd, and Jason W. Brooks.

Summary: "Designed to be both comprehensive and user-friendly, the text offers easy-to-understand explanations of medical terminology and contains helpful learning features such as tips, case studies, and review questions. Describes medical terms with easy-to-understand explanations and phonetic spellingsOffers an updated edition of this practical guide to veterinary medical terminologyContains real-world case studies, word lists, and review questions that are designed to promote active learningIncludes new chapters on medical reports and case studies and large animals, as well as helpful memorization featuresProvides access to a companion website with images, audio clips, flash cards, and other helpful learning tools"--Provided by publisher.

Contents:
1. Introduction
2. Anatomical organization
3. The musculoskeletal system
4. The gastrointestinal tract
5. The reproductive system
6. The cardiovascular system
7. The respiratory tract
8. Hematology
9. Immunology
10. The endocrine system
11. The integumentary system
12. The nervous system
13. The eyes and ears
14. The urinary system
15. The horse
16. Ruminants
17. Swine
18. Exotics
19. Laboratory animals
20. Case studies
Appendix A: Pronunciation and spelling of terms found in this book
Appendix B: Commonly used veterinary medical abbreviations
Recommended reading
Glossary
Answers
Index.

Summary: "Ever-evolving technological advances have created a daunting number of emergent neurointerventional protocols and therapies for treating acute ischemic stroke. This has created an urgent need for reader-friendly, hands-on resources. Video Atlas of Acute Ischemic Stroke Intervention edited by renowned neuroinventional stroke experts Maxim Mokin, Elad I. Levy, Adnan H. Siddiqui, and esteemed contributors fills a void in education and knowledge with interactive, case-based guidance on mastering challenging stroke interventions. The atlas leverages current knowledge and decades of experience in acute stroke treatment and device innovations to familiarize clinicians at various career stages with a wide repertoire of techniques available in the neurointerventional suite"-- Provided by publisher.

Summary: "Disorders of the anterior segment are a leading cause of ocular morbidity. As a result of structural abnormalities associated with trauma, degeneration, developmental disorders, or iatrogenic causes, reconstruction is required. Significant breakthroughs have been made in anterior segment reconstructive approaches, including the use of stem cells, selective tissue transplant, glued lenses, and advanced suturing techniques. Video Atlas of Anterior Segment Repair and Reconstruction: Managing Challenges in Cornea, Glaucoma, and Lens Surgery by renowned ophthalmic surgery pioneers Amar Agarwal, Priya Narang, and international contributors is the most comprehensive resource available to date on anterior segment surgery, reflecting cutting-edge innovations"-- Provided by publisher.

Summary: "Rotator cuff disorders are the most common cause of shoulder pain, accounting for up to 70% of cases. Tears are the most severe subtype, with a lifetime prevalence rate of more than 20%. The size, location, and severity of rotator cuff tears varies greatly, requiring equally diverse preoperative planning and surgical interventions. Video Atlas of Arthroscopic Rotator Cuff Repair by Uma Srikumaran and esteemed contributors provides a concise, well-rounded perspective on the surgical management of rotator cuff pathologies. Expert surgeons from across the globe describe and demonstrate numerous approaches, enabling clinicians to expand their armamentarium and achieve optimal outcomes. The opening chapters lay a solid foundation, covering basic techniques for arthroscopic repair of various rotator cuff tear patterns, patient positioning, portal placement, tips and tricks, complications, and pitfalls. Subsequent chapters succinctly discuss a comprehensive range of arthroscopic and transosseous techniques, biologic augmentation, grafting, tendon transfers, and superior capsular reconstruction"-- Provided by publisher.

Summary: References -- Part IV: Applications in Foregut Surgery -- 9: Anastomosis Viability Assessment During Esophagectomy -- Introduction -- Background -- ICG Applications in Surgery -- Esophagectomy: Surgical Options -- Minimally Invasive Esophagectomy (MIE) -- Anastomotic Perfusion: Before ICG -- ICG and Esophagectomy -- Technical Description of the Procedure -- Pitfalls -- Conclusion -- References -- 10: The Use of Near-Infrared Fluorescence in Sleeve Gastrectomy -- Introduction -- Indications -- Technical Description of Procedure -- Interpretation -- Pitfalls -- Conclusion -- References

Contents:
Intro
Preface
Contents
Contributors
1: Introduction to Near-Infrared Fluoroscopy in the Operating Room
Fluorophores
Applications
Augmented Reality
References
Part I: Applications in Endocrine Surgery
2: Fluorescence Applications in Parathyroid Surgery
Background
Indications
Technical Description of the Procedure
Indocyanine Green Fluorescence
Equipment
Adjustments and Configurations
Surgical Procedure
Other Techniques
Future Applications
Interpretation
Limitations
References
3: Applications in Adrenal Surgery
Indications Technical Description of the Procedure
Interpretation
Pitfalls
Literature Review
Conclusion
References
Part II: Applications in Neurosurgery
4: Clipping Cerebral Aneurysm
Introduction
Background
Microsurgical Clipping for CAs
Intraoperative Adjuncts
Doppler Ultrasonography
Neurophysiological Monitoring
Fluorescence Angiography
Conclusion
References
5: Cerebral Bypass Surgery
Overview of Cerebral Bypass
Fluorescence in Cerebral Bypass
Indocyanine Green
Sodium Fluorescein
Pitfalls
Cerebral Bypass for Flow Augmentation STA-MCA Bypass for Ischemia
STA-MCA Bypass for Moyamoya
Cerebral Bypass for Flow Replacement
Bypass for Giant and Complex Aneurysm
Conclusion
References
6: Vascular Malformation
Introduction
Background
Indication for Surgery
Preoperative Evaluation
Treatment
Intraoperative Adjuncts
Neurophysiological Monitoring
Evaluation of the Blood Flow
Conclusion
References
Part III: Applications in Cardiothoracic Surgery
7: Angiography During Cardiovascular Surgery
Indications
Intraoperative Techniques of Graft Patency Assessment Transit-Time Flowmetry (TTFM)
Technique
Current Experience and Results
Limitations
Intraoperative Fluorescence Imaging (IFI) System
Principle
Technique
Validation Studies
Interpretation
Clinical Results
Pitfalls
Conclusions
References
8: Lung Segmentation: The Combination of Lung Volume Analyzer VINCENT for Measuring Resection Margin and ICG Anatomical Segmentectomy
Indication
Technical Description of the Procedure
Creation of Virtual Segmentectomy
Transbronchial ICG Injection
Anatomical Sublobar Resection
Interpretation
Pitfalls

Summary: "Unlike traditional textbooks that detail natural history, physiology, and morphology, Video Atlas of Neuroendovascular Procedures presents basic and complex neuroendovascular procedures and cases with concise text and videos. Renowned neuroendovascular surgeons Leonardo Rangel-Castilla, Adnan Siddiqui, Elad Levy, and an impressive group of contributors have compiled the quintessential neuroendovascular resource. Organized into eight major subtopic sections, this superb video atlas covers a full spectrum of endovascular approaches to diagnose and treat intra- and extracranial neurovascular disease. The book starts with a section on vascular access and concludes with endovascular complications and management. Forty chapters includes succinct summaries, scientific procedural evidence, the rationale for endovascular intervention, anatomy, required medications, device selection, avoiding complications, and managing potential problems that can arise during procedures. The image-rich clinical cases feature insightful firsthand knowledge and pearls"-- Provided by publisher.

Summary: The surgical treatment of infiltrating brain tumors is an extremely challenging and often highly rewarding facet of neurosurgery. The decision-making process involves deeply human interconnections with patients and relatives, cutting-edge neuroscience, and fascinating technology. Video Atlas of Neurophysiological Monitoring in Surgery of Infiltrating Brain Tumors by renowned oncological neurosurgeon Michael Sabel and esteemed contributors demonstrates the practical applications of neurophysiological monitoring to achieve safe removal of infiltrating brain tumors in asleep and awake settings.Organized in three primary parts, the book starts with an introduction including a discussion of the impact and challenges posed by infiltrating gliomas and cerebral metastases and the philosophy behind supramarginal resection. The second part covers critical theoretical components including relevant anatomy, nervous system electricity and fields, transcranial monitoring methods and principles, and direct cortical and subcortical mapping including awake brain surgery. The final part provides insightful, practical guidance on decision making, monitoring set-up, planning of surgical cases, and a summary of accompanying videos- Provided by publisher.

Contents:
The Scope of This Book
The Challenge to Treat Infiltrating Brain Tumors
The Impact of Lesionectomy on the Prognosis of Infiltrating Intracerebral Tumors
The Philosophy Behind Supramarginal Resection : Functionality Becomes the Limit
The Relevant Anatomy of the Functional Systems
What You Need to Know About Electricity
Transcranial Monitoring : Methods to Monitor CNS Functions :Principles
Direct Cortical and Subcortical Mapping
Checklist for Awake Procedure
Introduction to the Practical Part
Setting up the Monitoring
The Surgery
Summary: Key Features from the Video
Epilogue.

Contents:
Introduction. Operating room requirements for brain tumor surgery
Awake craniotomy and speech mapping for gliomas
Cortical/subcortical motor mapping for gliomas
Trans-sulcal versus transcortical resection of subcortical metastases
Deep intra-axial tumors
Brainstem tumors
Cerebellar tumors
Cervicomedullary tumors
Supracerebellar infratentorial approach
Intraoperative assessment of extent of resection
Convexity and parasagittal meningiomas
Falcine and falcotentorial meningiomas
Posterior fossa meningiomas
Transcortical approach to the lateral ventricles
Transcallosal approach for intraventricular tumors
Telovelar approach
Endoscopic approach to the ventricles
Pterional craniotomy
Orbitozygomatic craniotomy
Supraorbital osteotomy : eyelid and eyebrow incisions
Subfrontal and extended subfrontal craniotomy/transbasal approach
Retrosigmoid versus extended retrosigmoid approach
The far lateral approach
Principles and anatomy in endoscopic endonasal surgery
Pituitary adenomas
Surgical treatment of craniopharyngiomas
Clival chordomas
Techniques for skull base reconstruction in endoscopic surgery
Combined subfrontal and endonasal approach
Combined transconjunctival and endonasal approach
Combined transmaxillary and subfrontal approach
Midline anterior skull base meningiomas
Sphenoid wing meningiomas
Parasellar tumors
Invasive pituitary adenomas
Approaches to the temporal bone : basic principles
Approaches to the orbit
Vestibular schwannomas
Foramen magnum meningiomas.

Contents:
Foundations of oculofacial plastic surgery
Chalazion incision and drainage
Upper blepharoplasty
Asian upper blepharoplasty
Asian eyelid crease formation (double eyelid operation) by suture ligation method
Revision of Asian upper eyelid crease
Root Z-epicanthoplasty
Mustardé's epicanthoplasty
Transconjunctival lower blepharoplasty with fat redraping
Transcutaneous lower blepharoplasty with orbitomalar suspension and fat redraping
Ptosis repair by external levator advancement
Ptosis repair by small incision external levator advancement
Ptosis repair by conjunctival Müller's muscle resection
Congenital ptosis repair by levator resection
Frontalis suspension with silicone rod
Repair of conjunctival prolapse
Upper eyelid retraction repair
Levator extirpation and frontalis suspension
Upper eyelid loading with platinum weight
Direct browplasty
Internal browplasty
Endoscopic browplasty
Pretrichial browplasty
Facelift by minimal access cranial suspension (macs)
Ectropion repair by retractor reinsertion and lateral tarsal strip
Ectropion repair by medial spindle
Ectropion repair with full thickness skin grafting
Canthus sparing drill hole canthoplasty
Entropion repair by transconjunctival approach
Entropion repair by Wies procedure
Entropion repair by posterior tarsotomy
Epiblepharon repair
Limited upper eyelid protractor myectomy
Lower eyelid retraction repair with porcine acellular dermal collagen matrix
Lower eyelid retraction repair with dermis fat
Lower eyelid retraction repair with hard palate grafting
Lower eyelid wedge resection and reconstruction
Lower eyelid reconstruction with periosteal flap and upper eyelid rotational flap
Lower eyelid reconstruction with semicircular flap
Lower eyelid reconstruction with Hughes' tarsoconjunctival flap
Lower eyelid reconstruction with Mustardé flap
Lateral canthal reconstruction with rhomboid flap
Upper eyelid reconstruction with cutler-beard flap and free tarsal graft
Temporal artery biopsy
Conjunctival pillar tarsorrhaphy
Lateral tarsorrhaphy
Autologous fat transfer to the tear trough
Hyaluronic acid gel filler to the inferior periorbita
Botulinum toxin treatment for lateral canthal rhytids (crow's feet)
Botulinum toxin treatment for glabellar rhytids
Botulinum toxin treatment for forehead rhytids
Thermal conjunctivoplasty
Endoscopic dacryocystorhinostomy
Endoscopic dacryocystorhinostomy with osteotome
Endoscopic dacryocystorhinostomy with lacrimal sac biopsy
Endoscopic revision of failed dacryocystorhinostomy
Endoscopic dacryocystorhinostomy with intranasal flap suturing
Endoscopic dacryocystorhinostomy with balloon dacryoplasty
Endoscopic conjunctivodacryocystorhinostomy
Bicanalicular intubation with silicone stent
Treatment of canaliculitis
Silicone stent intubation with pigtail probe
Snip punctoplasty
Three wall orbital decompression
Lateral orbitotomy with rim removal
Inferior orbitotomy for cavernous hemangioma
Orbital fracture repair
Orbital floor reconstruction in silent sinus syndrome
Transcaruncular approach to ethmoidal artery ligation
Reposition of prolapsed lacrimal gland
Optic nerve sheath fenestration
Evisceration with orbital implant placement
Enucleation and orbital implant placement
Orbital exenteration
Orbital implant exchange with dermis fat graft
Multidisciplinary management of orbital varix.

Contents:
Historical perspective
Safety
Basic principles
Basics of wound healing and the role of suture
Ophthalmic surgical suture : properties, design, and selection
Suture needles
Needle holders and forceps
Suturing : basic skills and techniques
Common errors
Complications
Self-assessment quiz.

Summary: A high-yield and comprehensive text-and-video resource for managing commonly encountered spinal conditions Spine surgery has experienced several paradigm shifts during the past few decades, with highly complex techniques introduced at an astoundingly rapid pace. In order for new generations of spine surgeons to stay current and thrive in this innovative era of spine surgery, access to diverse multimedia learning tools is imperative. Video Atlas of Spine Surgery by renowned spine surgeon and educator Howard An and Rush University Medical Center colleagues Philip Louie, Bryce Basques, and Gregor.

Summary: This book is simultaneously a superb atlas and a detailed guide to all aspects of video capsule endoscopy. History, technique, performance, reading, indications, contraindications, outcomes, complications and alternative methods are described systematically by a large panel of experts. In addition, the full range of small bowel diseases, from the common to the rare, are described and illustrated using a unique and exhaustive collection of capsule endoscopy images that are accompanied by corresponding images of enteroscopy, surgery, radiology and histology whenever possible. The newest technology of colon capsule endoscopy is included and exciting potential future developments are also considered. This book will be indispensable for all who use the technique or are considering establishing a video capsule endoscopy service.

Contents:
Video Capsule Endoscopy
Complementary Procedures
Normal Small Intestine
Diverticula
Vascular Diseases of the Small Intestine
Inflammatory and Systemic Diseases
Tumors of the Smal Intestine
Findings Outside the Small Intestine
Postoperative and Postinterventional Changes
Complications:Prevention and Management
Pediatric Findings
Influence of VCE on Clinical Outcome
Esophageal Capsule Endoscopy
Future Developments of Capsule Endoscopy.

Summary: This book explores the issue of violence in detail, taking into account the role of contextual factors, as well as the epidemiology, risk factors and clinical aspects of violence related to the main mental disorders. It also offers practical information on its management - from prevention to treatment. Covering all aspects of the problem of violence in mental disorders, the book is divided into four parts: general aspects; risk factors, phenomenology and characteristics of violence in mental disorders; contexts of violence; and prevention and management of violence in mental health. It also discusses violence in the various settings of mental health system, an aspect that has not previously been fully addressed. The volume is intended for all those who are interested in mental health, including scholars, professionals, and students.

Contents:
Section I General aspects.-Violence as a social, clinical and forensic problem.-Biological basis of violence in mental disorders.-Epidemiology and risk factors for violence in people with mental disorders.-Section II Risk Factors, phenomenology and characteristics of violence in mental disorders.-Violence in major mental disorders
Psychopaty, personality disorders and violence
Substance use disorders and violence.-Violence and PTSD
Major Neurocognitive disorders and violence.-Section III The contexts of violence.-Studying patients with severe mental disorders who act violently: Italian and European projects.-Prevalence and risk factors of violence by psychiatric acute inpatients: systematic review and meta-analysis. A 2019 Update
Violence and mental disorders in Jails.-Violent behavior in Forensic Residential Facilities: the Italian experience after the closure of Forensic Psychiatric Hospitals.-Section IV Prevention and management of violence in mental health
Violence Risk Assessment in mental health.-Psychoparmacology of violent behaviour among people with severe mental disorders.-Non Pharmacological approaches to violence among people with severe mental disorders.

Summary: Violence is one of the most important challenges, not only for public health systems, but also for public mental health. Violence can have immediate as well as long-term and even transgenerational effects on the mental health of its victims. This book provides a comprehensive and wide-ranging assessment of the mental health legacy left by violence. It addresses the issues as they affect states, communities and families, in other words at macro-, meso-, and microlevels, beginning by describing the impact of violence on neurobiology and mental health, as well as the spectrum of syndromes and disorders associated with different forms of violence. ℗ℓ The work moves on to tackle violence at the international and intranationalℓ́ℓlevel before zeroing in on the nature of violence in communities such as villages or city districts. It also examines the results of violence in the family. Each type of violence has distinct effects on mental health, and in each chapter specific groups are explored in depth to demonstrate the heterogeneity of violence as well as the diversity of its outcomes in the realm of public mental health. Finally, the book addresses the notion of undoing violenceℓ́ℓ by detailing case studies of effective interventions and prevention occurring in countries, communities and families. These cases give us pause to reflect on the nature of resilience and dignity in the context of violence and mental health. All the chapters have been written by leading authors in the field and provide a state-of-the-art perspective. The authors, from different fields of expertise, facilitate interdisciplinary and international insights into the impact of violence on mental health.

Contents:
Preface: Martin McKee
Foreword: Jutta Lindert, Itzhak Levav
Part 1: General Issues in Violence and Health: Chapter 1: Violence in Prolonged Conflicts and its Socio-Psychological Effects: Iris Lavi, Danier Bar-Tal
Chapter 2: Intergenerational Transmission on Violence: Cathy Spatz Widom, Helen W. Wilson
Chapter 3: Violence and Mental Health States: Jutta Lindert
Part II: Self-Inflicted Violence, A Public Health Challenge: Chapter 4: Self-Inflicted Violence: Jose Manuel Bertolote, Diego de Leo
Part III: Violence in Families: Chapter 5: Child Abuse and Adult Psychopathology: Gilad Gal, Yael Basford
Chapter 6: Corporal Punishment and Children's Mental Health: Opportunities for Prevention: Lawrence Wissow
Chapter 7: Mental Health Consequences of Violence against Women: Jane Fisher, Meena Cabral de Mello
Chapter 8: The Consequences of Violence on the Mental Health of the Elderly: Robert Kohn
Part IV: Violence in Communities: Chapter 9: Bullying in Schools: Rates, Correlates and Impact on Mental Health: Sheryl Hemphill, Michelle Tollit, Aneta Kotevski, Ariane Florent
Chapter 10: Violence against People with Mental Disorders: Angelo Barbato
Chapter 11: 'This is where the Seed is Sown': Aboriginal Violence
Continuities or Contexts? : Ernest Hunter, Leigh-Ann Onnis
Chapter 12: Trafficked Persons and Health: Itsvan Szilard, Arpad Barath
Part V: Violence in Societies: Chapter 13: Terrorism and its Impact on Mental Health: Sasha Rudenstine, Sandro Galea
Chapter 14: Political Persecution in the German Democratic Republic between 1949 and 1989 and it consequences for Mental and Physical Health: Gregor Weiflog, Elmar Brahler
Chapter 15: The Aftermath of the European and Rwandan Genocides: Itzhak Levav
Chapter 16: The New H5 Model of Refugee Trauma and Recovery: Richard F. Mollica, Robert Brooks, Solvig Ekblad, Laura McDonald
Part VI: Outlook: Evidence based Models of Prevention and Intervention: Chapter 17: Evidence based Interventions for Violent Behavior in Children: Sajid Humayun, Stephen Scott
From Sharpeville to Marikana: The Changing Political Landscape for Mental Health Practice in a Violent South Africa: Leslie Swartz.

Summary: This book gathers full papers presented at the VipIMAGE 2019--VII ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing--held on October 16-18, 2019, in Porto, Portugal. It discusses cutting-edge methods, findings, and applications related to 3D vision, bio- and medical imaging, computer-aided diagnosis, image enhancement, image processing and analysis, virtual reality, and also describes in detail advanced image analysis techniques, such as image segmentation and feature selection, as well as statistical and geometrical modeling. The book provides both researchers and professionals with extensive and timely insights into advanced imaging techniques for various application purposes.

Contents:
Colonic Polyp Identification Using Pareto Depth Anomaly Detection Algorithm
Comparative Study of Dermoscopic Hair Removal Methods
Lower Limb Joint Angle Coordination Assessment at Sagittal Plane on Human Vertical Countermovement
Biometric Identification Based on Forearm Vein Pattern
Cross Recurrence Quantitative Analysis of Functional Magnetic Resonance Imaging
Automatic Segmentation and Delineation of Intervertebral Discs on Lumbar Spine MR Images
A Hybrid Approach For Breast Mass Categorization
Skin Disease Diagnosis from Photographs Using Deep Learning
Prediction of the Childs Head Growth in the First Year of Life
Influence of Mutual Rotation of Polarizing Filters on Light Intensity Measured With Collagen Fibres
Automatic Extraction of Marbling Measures Using Image Analysis, for Evaluation of Beef Quality
Layer Thickness Evaluation Between Medical Imaging and Additive Manufacturing.

Summary: "This book dissects medical myths and pseudoscience and explores how misinformation can spread faster than microbes. Yasmin debunks public health myths ranging from the spurious link between vaccines and autism to the truth about so-called chemtrails left behind by airplanes. In short chapters covering popular myths, Yasmin parses the science behind fearful rumors and models how to be a more informed consumer of health news"-- Provided by publisher.

Contents:
Do the flat tummy detox teas touted by Instagram celebrities actually work?
Should you eat your baby's placenta?
Do vaccines cause autism?
Can autism be cured?
Are children being paralyzed by the common cold virus?
Do we inherit trauma from our parents?
Are genetically modified foods safe?
How long can you eat leftovers?
Is MSG addictive?
Is drinking diet soda linked to Alzheimer's disease and stroke?
Do mammograms cause more problems than they detect?
Is it dangerous to be pregnant in America?
The raging statin debate: Should you take a cholesterol-lowering drug?
Does aspirin prevent cancer?
Did the maker of aspirin test medicines in Nazi concentration camps?
Does the birth control pill cause depression?
Do vitamin D supplements protect against obesity, cancer and pneumonia?
Will fish oil supplements prevent heart disease or give you cancer?
Are heartburn medicines linked to a serious gut infection?
Were dietary supplements linked to a deadly outbreak of hepatitis?
Can gay and bisexual men donate blood?
Are e-cigarettes helpful or harmful?
Is marijuana a performance enhancing drug for athletes?
Did a morning sickness pill for pregnant women cause birth defects in thousands of babies?
Is there lead in your lipstick?
Why do immigrants in America live longer than American-born people?
Has the US government banned research about gun violence?
The Frackademia Scandal: Did oil and gas companies pay academics to say fracking was safe?
Does playing American football give players brain damage?
Did the US government infect people with syphilis and gonorrhea?
Does talcum powder cause ovarian cancer?
Does infection with Ebola cause lifelong symptoms?
Are older adults at higher risk of contracting sexually transmitted infections?
Did genetically modified mosquitoes spread Zika, and does the virus cause birth defects?
Can your cat's poop make you better at business?
Is suicide contagious?
Are suicide rates linked to the economy?
Are there more suicides during the holiday season?
Are you more likely to die from a medical mistake than a car crash?
Is it dangerous to go to the hospital in July?
Do patients cared for by female doctors live longer?
Can a pill make racists less racist?
Are airplane condensation trails, aka chemtrails, bad for your health?
Do bad teeth cause heart disease?
Can your zip code predict when you will die?
Does debunking a myth help it spread?

Summary: This book presents up-to-date, practically oriented information on major topics in acute hepatitis. The coverage encompasses epidemiology; diagnosis, including molecular methods; treatment and challenges; and the management of co-infections. The book opens by examining the local and global epidemiology of acute hepatitis. Detailed attention is then paid to each of acute hepatitis A, acute hepatitis B, acute hepatitis C, hepatitis D co-infection, and hepatitis E. Acute Hepatitis will be of high value for general practitioners and specialists in gastroenterology, infectious diseases, and internal medicine. It will be international in scope in terms of both authorship and appeal.

Contents:
Local and global epidemiology of acute hepatitis
Acute hepatitis A
Acute hepatitis B
Acute hepatitis C
Hepatitis D co-infection
Hepatitis E.

Summary: This book presents up-to-date, practically oriented information on major topics in chronic hepatitis B. The coverage encompasses epidemiology; diagnosis, including molecular methods; treatment and challenges; and the management of co-infections. Readers will also find guidance on the invasive and non-invasive assessment of fibrosis in HBV infection and the prevention of mother-to-child transmission of HBV. Management of chronic hepatitis B in children is considered separately, and emerging drugs that hold promise for the treatment of chronic HBV infection are discussed. Chronic Hepatitis B will be of high value for general practitioners and specialists in gastroenterology, infectious diseases, and internal medicine. It will be international in scope in terms of both authorship and appeal.

Contents:
Natural course of chronic HBV infection
Management of chronic HBV infection in children
Epidemiology of HBV infection
Genetic diversity of the hepatitis B virus and its epidemiological significance
Laboratory diagnosis of HBV
Prevention of mother-to-child transmission of HBV
Current management of chronic HBV infection
Current management of hepatitis B co-infected with hepatitis D
Future drugs in the treatment of chronic HBV infection.

Summary: This book presents up-to-date, practically oriented information on major topics in chronic hepatitis C. The coverage encompasses epidemiology; diagnosis, including molecular methods; treatment and challenges; and the management of co-infections. Readers will find guidance on pretherapeutic evaluation with respect to disease severity and extrahepatic manifestations. Resistance to antiviral treatment and its management are discussed, and the nature of optimal follow-up is addressed in detail. Treatment of HCV/HIV co-infection is considered separately, and the approach in special patient populations is thoroughly examined. Chronic Hepatitis C will be of high value for general practitioners and specialists in gastroenterology, infectious diseases, and internal medicine. It will be international in scope in terms of both authorship and appeal.

Contents:
1.Pretherapeutic evaluation of the patients and evaluation of the severity of hepatic disease
2.HIV HCV co-infection: current challenges
3.TREATMENT OF HEPATITIS C VIRUS INFECTED PATIENTS WITH RENAL FAILURE
4.Global Epidemiology of Chronic Hepatitis C Virus Infection
5.LABORATORY AND MOLECULAR DIAGNOSIS OF HEPATITIS C AND RESISTANCE TESTING
6.EXTRAHEPATIC MANIFESTATIONS OF HEPATITIS C VIRUS INFECTION
7.Current Therapy of Chronic Hepatitis C Virus in Treatment Naive Patients
8.Management of Interferon-Free Direct-Acting Antiviral Therapy Failure
9.Management of HCV Infection In Decompen-sated Cirrhosis In The Transplantation Setting
10.Treatment of Hepatitis C Virus in Special populations (HBV co-infection, Drug users and prisoners)
11.Acute Hepatitis C.

Summary: This book is aimed to emphasize the rationale and importance of prevention and management of viral hepatitis in children, providing cutting edge knowledge. Viral hepatitis is a major health problem in the world. Although most complications of viral hepatitis are observed in adults, primary infection with hepatitis viruses often occurs during infancy or childhood. To better control viral hepatitis, prevention and therapy if possible should be started in childhood. This book offers updated and unique information about viral hepatitis in children, which has vitally important impact on global disease outcome and control, yet not discussed as frequently as viral hepatitis in adults in previous medical literature. Better prevention and management strategies are covered, starting from infancy and childhood, and even earlier during fetal life. It will be very helpful for better control of viral hepatitis both for daily practice and for developing future strategies and directions. If we can successfully control viral hepatitis in children, there will be very little remaining chronic hepatitis and related complications such as liver cirrhosis or hepatoma in adults. We hope readers, including medical students, researchers, pediatricians, family medicine physicians, infectious disease personnel, public health workers, gastroenterologists, hepatologists and parents of children with chronic hepatitis, will be benefited by reading this book.

Contents:
Chapter 1: Control of Viral Hepatitis
A Good Start from Childhood (Kathy Schwarz)
Chapter 2: Epidemiology of Viral Hepatitis A and E
A Global View ( Kenrad Nelson)
Chapter 3: Epidemiology of Viral Hepatitis B, C and D
A Global View (Hwai-I Yang)
Chapter 4: Mother-to Infant Transmission of Viral Hepatitis (Hueyling Chen)
Chapter 5: Viral Hepatitis A in Children
Detection and Management (Yang Poovorawan)
Chapter 6: Prevention of Hepatitis A (Daniel Shouval)
Chapter 7: Natural History of Hepatitis B Virus Infection
From Infancy to Adult life (Yen-Hsuan Ni )
Chapter 8: Immune Tolerance and Hepatitis B (Antonio Bertoletti)
Chapter 9: Prevention of Viral Hepatitis B and related Complications (Mei-Hwei Chang)
Chapter 10: Viral Hepatitis B
Management in Children (Christine Lee)
Chapter 11: Natural History of Hepatitis C Virus Infection in Children (Karen Murray)
Chapter 12: Management of Viral Hepatitis C in Children (Björn Fischler)
Chapter 13: Hepatitis D in Children
Diagnosis, Management, and Prevention (Daniel H Leung)
Chapter 14: Hepatitis E in Children
Diagnosis, Management, and Prevention (Wikrom Karnsakul)
Chapter 15: Viral Causes of Acute Liver Failure (Rob Squires)
Chapter 16: Emerging New Strategies for Viral Hepatitis Control (Chia-Ho Shih).

Summary: A timely exploration of the impact of global change on the emergence, reemergence, and control of vector-borne and zoonotic viral infections From massively destructive ""superstorms"" to rapidly rising sea levels, the world media is abuzz with talk of the threats to civilization posed by global warming. But one hazard that is rarely discussed is the dramatic rise in the number and magnitude of tropical virus outbreaks among human populations. One need only consider recent developments, such as the spread of chikungunya across southern Europe and dengue in Singapore, Brazil, and the so

Summary: Striking changes have occurred in the world since the publication of the last edition of Viral Infections of Humans. The global population is rapidly approaching 8 billion; climate change is leading to the introduction of new hosts, vectors and virus diseases heretofore never seen in many parts of the world; technological advances have revolutionized the ability to recognize and characterize viruses new and old; vaccines are altering the epidemiological landscape of the diseases they target, in some cases raising the hope of their eradication; and remarkably powerful computational tools are enabling not only detection of outbreaks of disease much sooner than in the past but also, through complex mathematical modeling, more accurate prediction of their potential impact. The new Fifth Edition of Viral Infections of Humans captures both the excitement and frustration of the dynamic struggle between humankind and the viruses that continue to cause immense suffering. It presents the latest concepts, methods, and technologies in epidemiology, detection, investigation, modeling, and intervention. Updated and entirely new chapters by dozens of experts across the field provide analytic summaries of current knowledge of viruses and prions causing acute syndromes, chronic illnesses, and/or malignancies. In sum, this ambitiously expanded volume offers a uniquely comprehensive perspective on viruses in humans, from agents of classic diseases (e.g., hepatitis, measles, polio, rabies, and yellow fever), to those with greatest pandemic impact (e.g., influenza and human immunodeficiency virus), to those discovered relatively recently (e.g., henipavirus, metapneumovirus, and norovirus). The new Fifth Edition of Viral Infections of Humans is an invaluable reference for students, fellows and established professionals in the fields of microbiology, public health and infectious disease epidemiology, medicine, and health policy.

Contents:
Epidemiology and Control: Principles, Practice and Programs
Diagnosis, Discovery and Dissection of Viral Diseases
Immunological Detection and Characterization
Surveillance and Seroepidemiology
Viral Dynamics and Mathematical Models
Adenoviruses
Alphaviruses: Equine Encephalitis and Others
Arenaviruses: Lassa Fever, Lujo Hemorrhagic Fever, Lymphocytic Choriomeningitis, and the South American Hemorrhagic Fevers
Bunyaviruses: Hantavirus and Others
Coronaviruses
Enteroviruses and Parechoviruses: Echoviruses, Coxsackieviruses, and Others
Enteroviruses: Enterovirus 71
Enteroviruses: Polio
Filoviruses: Marburg and Ebola
Flaviviruses: Dengue
Flaviviruses: Yellow Fever, Japanese B, West Nile, and Others
Hepatitis A Virus
Hepatitis E Virus
Influenza Viruses
Noroviruses, Sapoviruses, and Astroviruses
Orthopoxviruses: Variola, Vaccinia, Cowpox, and Monkeypox
Paramyxoviruses: Henipaviruses
Paramyxoviruses: Measles
Paramyxoviruses: Mumps
Paramyxoviruses: Parainfluenza Viruses
Paramyxoviruses: Respiratory Syncytial Virus and Human Metapneumovirus
Parvoviruses
Rhabdovirus: Rabies
Rhinoviruses
Rotaviruses
Rubella Virus
Hepatitis Viruses: Hepatitis B and Hepatitis D
Hepatitis Viruses: Hepatitis C
Hepatitis Viruses: Hepatocellular Carcinoma
Human Herpesviruses: Cytomegalovirus
Human Herpesviruses: Herpes Simplex Virus Types 1 and 2
Human Herpesviruses: Human Herpesvirus 6
Epstein-Barr Virus (EBV): Infectious Mononucleosis and Other Non-malignant EBV-Associated Diseases
Kaposi's Sarcoma-Associated Herpesvirus: Epidemiology, Biological Characteristics and Pathogenesis
Human Herpesviruses: Malignant Lymphoma
Epstein-Barr Virus: Nasopharyngeal Carcinoma and Other Epithelial Tumors
Human Herpesviruses: Varicella and Herpes Zoster
Human Immunodeficiency Viruses Types 1 and 2
Human Papillomaviruses: Cervical Cancer and Warts
Human T-Cell Leukemia Viruses Types 1 and 2
Polyomaviruses: Progressive Multifocal Leukoencephalopathy and Other Diseases.

Summary: This volume of original essays explores the power of network thinking and analysis for humanities research. Contributing authors are all scholars whose research focuses on a medical history topic--from the Black Death in fourteenth-century Provence to psychiatric hospitals in twentieth-century Alabama. The chapters take readers through a variety of situations in which scholars must determine if network analysis is right for their research; and, if the answer is yes, what the possibilities are for implementation. Along the way, readers will find practical tips on identifying an appropriate network to analyze, finding the best way to apply network analysis, and choosing the right tools for data visualization. All the chapters in this volume grew out of the 2018 Viral Networks workshop, hosted by the History of Medicine Division of the National Library of Medicine (NIH), funded by the Office of Digital Humanities of the National Endowment for the Humanities, and organized by Virginia Tech.

Summary: Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the design and development of inhibitors, and analyze the structure-activity relationships of inhibitors. This book is ideal biochemists, virologists and those working on antiviral agents.

Contents:
Fundamentals of viruses and their proteases / Anjana Sharma, Satya P. Gupta
Design and development of some viral protease inhibitors by QSAR and molecular modeling studies / Noha A. Saleh, Hanan Elhaes, Medhat Ibrahim
Advances in studies on adenovirus proteases / Satya P. Gupta, Basheerulla Shaik, Yenamandra S. Prabhakar
Alphavirus nonstructural proteases and their inhibitors / Akalabya Bissoyi, Subrat K. Pattanayak, Arindam Bit, Ashish Patel, Abhishek K. Singh, Sudhanshu S. Behera, Debabrata Satpathy
Structure and function of aplhavirus proteases / Shailly Tomar, Megha Aggarwal
Flavivirus protease / Shailly Tomar, Rajat Mudgal, Benazir Fatma
Flavivirus NS2B/NS3 protease / Zhong Li, Jing Zhang, Hongmin Li
Design and development of HCV NS5B polymerase inhibitors / Debasis Das
Studies on HIV-1 protease and its inhibitors / Sonal Dubey
Studies on picornaviral proteases and their inhibitors / Vaishal M. Patil, Satya P. Gupta
Structural insight into viral 3C-like protease inhibitors / Nilanjan Adhikari, Sandip K. Baidya, Achintya Saha, Tarun Jha
Herpesvirus proteases / Kriti Kashyap, Rita Kakkar
Design and development of inhibitors of herpes viral proteases and their SAR and QSAR / Dimitra Hadjipavlou-Litina, Satya Gupta
Delicate dance in treating hepatitis c infections and overcoming resistance / Dolly A. Parasrampuria.

Summary: This highly accessible textbook introduces readers to the development of viral vectors and discusses their application in veterinary vaccinology. It offers comprehensive information on the latest advances in this emerging research field, together with a broad overview of the history of veterinary vaccines and viral vectors. The book also addresses issues concerning funding, translational research and ethics that will impact the future development, manufacture and global use of viral vector-based veterinary vaccines. The book addresses the needs of graduate students and researchers in the fields of Veterinary Medicine, Virology and Immunology.

Contents:
Chapter 1. Introduction to Veterinary Vaccines
Chapter 2. "What is Required to Develop a Viral Vector Vaccine: Key Components of Vaccine-Induced Immune Responses"
Chapter 3. Viruses and the evolution of viral vectors
Chapter 4. The role of adjuvants in the application of viral vector vaccines
Chapter 5. Adenovirus Vectors
Chapter 6. Poxvirus Vectors
Chapter 7. The Construction and Evaluation of Herpesvirus Vectors
Chapter 8. Paramyxoviruses as Vaccine Vectors
Chapter 9. Rhabdoviruses as vaccine vectors for veterinary pathogens
Chapter 10. Coronaviruses as Vaccine Vector for Veterinary Pathogens
Chapter 11. Alphavirus-Based Vaccines
Chapter 12. Manufacturing and Control of Viral Vectored Vaccines: Challenges
Chapter 13. Regulatory strategies and factors affecting veterinary viral vector development
Chapter 14. "Emerging Viral Vectored Technology Future potential of capripoxvirus and African swine fever virus as viral vectors."

Summary: "A leading microbiologist tackles the scientific and sociopolitical impact of viruses in twelve striking essays. Invisible in the food we eat, the people we kiss, and inside our own bodies, viruses flourish-with the power to shape not only our health, but our social, political, and economic systems. Drawing on his expertise in microbiology, Joseph Osmundson brings readers under the microscope to understand the structure and mechanics of viruses and to examine how viruses like HIV and COVID-19 have redefined daily life. Osmundson's buoyant prose builds on the work of the activists and thinkers at the forefront of the HIV/AIDS crisis and critical scholars like José Esteban Muñoz to navigate the intricacies of risk reduction, draw parallels between queer theory and hard science, and define what it really means to "go viral." This dazzling multidisciplinary collection offers novel insights on illness, sex, and collective responsibility. Virology is a critical warning, a necessary reflection, and a call for a better future"-- Provided by publisher.

Contents:
On risk
On replication
On going viral
On private writing
On HIV and Truvada
On war / with Patrick Nathan
On mentors
On whiteness
On activism and the archives
On endings
On evolution.

Summary: This book is unique in its approach, covering the impact of virtual endoscopy and 3D reconstruction on surgical modalities and perioperative airway options. Airway management is an essential skill that is practiced daily by almost all anesthetists across the world. Most of the anesthesia-related morbidities and mortalities in the perioperative period are associated with respiratory complications, either of airway or pulmonary problems. Thus, the prediction of airway complications in perioperative period has been an active research field for many decades and is a cornerstone of perioperative anesthesia assessment and management. Virtual endoscopy & 3D reconstruction is a novel, reliable and non-invasive airway assessment tool that is able to reconstruct simple CT images to provide a clear view of the airway down to the bronchial trees, and offers the highest possible sensitivity, comparable with fiberoptic endoscopic pictures. This revolutionary tool avoids the hazards of invasive airway assessment by fiber-optic bronchoscopy, like bleeding from airway masses, sedation induced airway collapse and other complications. This book is a valuable resource for anesthesiologists, intensivists, surgeons, radiologists, otolaryngologists, medical students as well as residents in training.

Contents:
Chapter 1 Introduction
Chapter 2 Review of Upper Airway Anatomy and Its Clinical Application
Chapter 3 Radiological Evaluation of the Airway, One Stop-Shop
Chapter 4 Evaluation of the Normal Airway Using Virtual Endoscopy and Three-Dimensional Reconstruction
Chapter 5 Virtual Endoscopy and 3D Reconstruction in Patients with Airway Pathology
Chapter 6 Virtual Endoscopy and 3D Reconstruction in the Nose, Paranasal Sinuses and Skull Base Surgery: New Frontiers
Chapter 7 Computer Assisted 3D Reconstruction of Oral and Maxillofacial Surgeries
Chapter 8 Virtual Endoscopy and 3D Reconstruction/Prototyping in Head and Neck Surgeries
Chapter 9 Perspectives in the Current and Future Use of Augmented Reality Visualization in Thoracic Surgery and Pulmonary Interventions
Chapter 10 Role of Virtual Endoscopy and 3-D Reconstruction in Airway Assessment of Critically Ill Patients
Chapter 11 Three-Dimensional Printing and Its Implication on Airway Management
Chapter 12 Challenging Cases Discussion.

Summary: This book offers a nuanced and complex look at defiance, taking seriously issues of dysfunction while also attending to the social contexts in which defiant behaviour may arise. Case studies, a framework for differentiating different forms of defiance, and a realistic picture of phronesis (practical reasoning) are all covered.

Contents:
1. Family resemblances: Compliance, the right to refuse treatment, noncompliance, resistance, reactance, and defiance
2. Theorizing defiance
3. Good defiance and flourishing
4. Interpreting defiant behavior in children: Constructs, norms, and intersectionalities
5. Bad and good defiance: Practical reasoning as guide
6. The virtue of giving uptake in psychiatry.

Summary: Presents a compilation of bacterial virulence strategies and cutting-edge therapies that have been unraveled in recent years. Serves as a textbook for graduate courses on bacterial pathogenesis. Also a useful resourse for veterinary scientists, food microbiologists, and other established researchers interested in pathogenesis.

Contents:
Preface
Acknowledgments
Chapter 1 : Evolution of Bacterial Pathogens Within the Human Host / Kimberly A. Bliven, Anthony T. Maurelli
Chapter 2 : Bacterial Metabolism Shapes the Host-Pathogen Interface / Karla D. Passalacqua, Marie-Eve Charbonneau, Mary X.D. O'Riordan
Chapter 3 : Iron Acquisition Strategies of Bacterial Pathogens / Jessica R. Sheldon, Holly A. Laakso, David E. Heinrichs
Chapter 4 : Sociomicrobiology and Pathogenic Bacteria / Joao B. Xavier
Chapter 5 : Candida-Bacteria Interactions: Their Impact on Human Disease / Devon L. Allison, Hubertine M. E. Willems, J.A.M.S. Jayatilake, Vincent M. Bruno, Brian M. Peters, Mark E. Shirtliff
Chapter 6 : Microbial Endocrinology in the Pathogenesis of Infectious Disease / Mark Lyte
Chapter 7 : Small RNAs in Bacterial Virulence and Communication / Sarah L. Svensson, Cynthia M. Sharma
Chapter 8 : Bacterial Secretion Systems: An Overview / Erin R. Green, Joan Mecsas
Chapter 9 : The Structure and Function of Type III Secretion Systems / Ryan Q. Notti, C. Erec Stebbins
Chapter 10 : Mechanism and Function of Type IV Secretion During Infection of the Human Host / Christian Gonzalez-Rivera, Minny Bhatty, Peter J. Christie
Chapter 11 : Type V Secretion Systems in Bacteria / Enguo Fan, Nandini Chauhan, D. B. R. K. Gupta Udatha, Jack C. Leo, Dirk Linke
Chapter 12 : The Versatile Type VI Secretion System / Christopher J. Alteri, Harry L.T. Mobley
Chapter 13 : Type VII Secretion: A Highly Versatile Secretion System / Louis S. Ates, Edith N. G. Houben, Wilbert Bitter
Chapter 14 : Stress Responses, Adaptation, and Virulence of Bacterial Pathogens During Host Gastrointestinal Colonization / Annika Flint, James Butcher, Alain Stintzi
Chapter 15 : Bacterial Evasion of Host Antimicrobial Peptide Defenses / Jason N. Cole, Victor Nizet
Chapter 16 : Antigenic Variation in Bacterial Pathogens / Guy H. Palmer, Troy Bankhead, H. Steven Seifert
Chapter 17 : Mechanisms of Antibiotic Resistance / Jose M. Munita, Cesar A. Arias
Chapter 18 : Chronic Bacterial Pathogens: Mechanisms of Persistence / Mariana X. Byndloss, Renee M. Tsolis
Chapter 19 : The Staphylococcal Biofilm: Adhesins, Regulation, and Host Response / Alexandra E. Paharik, Alexander R. Horswill
Chapter 20 : Surviving Between Hosts: Sporulation and Transmission / Michelle C. Swick, Theresa M. Koehler, Adam Driks
Chapter 21 : Staying Alive: Vibrio cholerae's Cycle of Environmental Survival, Transmission, and Dissemination / Jenna G. Conner, Jennifer K. Teschler, Christopher J. Jones, Fitnat H. Yildiz
Chapter 22 : Hijacking and Use of Host Lipids by Intracellular Pathogens / Alvaro Toledo, Jorge L. Benach
Chapter 23 : Contrasting Lifestyles Within the Host Cell / Elizabeth Di Russo Case, James E. Samuel
Chapter 24 : Intracellular Growth of Bacterial Pathogens: The Role of Secreted Effector Proteins in the Control of Phagocytosed Microorganisms / Valérie Poirier, Yossef Av-gay
Chapter 25 : Cellular Exit Strategies of Intracellular Bacteria / Kevin Hybiske, Richard Stephens
Chapter 26 : Novel Targets of Antimicrobial Therapies / Sarah E. Maddocks
Chapter 27 : Innovative Solutions to Sticky Situations: Antiadhesive Strategies for Treating Bacterial Infections / Zachary T. Cusumano, Roger D. Klein, Scott J. Hultgren
Chapter 28 : The Role of Biotin in Bacterial Physiology and Virulence: a Novel Antibiotic Target for Mycobacterium tuberculosis / Wanisa Salaemae, Grant W. Booker, Steven W. Polyak
Chapter 29 : Recent Advances and Understanding of Using Probiotic-Based Interventions to Restore Homeostasis of the Microbiome for the Prevention/Therapy of Bacterial Diseases / Jan S. Suchodolski, Albert E. Jergens
Index.

Summary: This book focuses on the important discoveries of the small molecule-, peptide-, and protein-based virus entry inhibitors and discusses advance of the development of different type of virus entry inhibitors as a novel class of antiviral drugs for treatment and prevention of viral infection. It includes entry inhibitors of HIV,HeV, NiV, RSV, EBOV, HCoV, HBV, HCV, HDV, HPV, flavivirus and influenza virus, so on. This book aims at providing an updated knowledge on virus entry inhibitors.

Contents:
Genetic engineering and chemical conjugation of potato virus X / Karin L. Lee, Kerstin [and four others]
Genetically engineering adenoviral vectors for gene therapy / Lynda Coughlan - Simulated digestion for testing the stability of edible vaccine based on Cucumber mosaic virus (CMV) chimeric particle display Hepatitis C virus (HCV) peptide / Antonella Vitti [and three others]
Using phage as a platform to select cancer cell-targeting peptides / Xin Li and Chuanbin Mao
Bacteriophage T4 capsid packaging and unpackaging of DNA and proteins / Julienne M. Mullaney and Lindsay W. Black
Templated mineralization by charge-modified cowpea mosaic virus / Alaa A.A. Aljabali and David J. Evans
Polyelectrolyte-modified cowpea mosaic virus for the synthesis of gold nanoparticles / Alaa A.A. Aljabali and David J. Evans
Tobacco mosaic virus capsid protein as targets for the self-assembly of gold nanoparticles / Omar K. Zahr and Amy Szuchmacher Blum
Tobacco mosaic virus assembled high aspect ratio surfaces / Adam D. Brown and James N. Culver
Phage as a template to grow bone mineral nanocrystals / Binrui Cao, Hong Xu, and Chuanbin Mao
Genetic engineering and characterization of cowpea mosaic virus empty virus-like particles / Frank Sainsbury [and five others]
A programmable fluorescent viral nanoblock : sensing made easy in a single step / Carissa M. Soto
Chemical modification of the inner and outer surfaces of tobacco mosaic virus (TMV) / Michael A. Bruckman and Nicole F. Steinmetz
Engineered bacteriophage T4 nanoparticles for cellular imaging / Jinny L. Liu and Kelly L. Robertson
Phage-displayed single domain antibodies as recognition elements / Ellen Goldman and Scott Walper
Molecular targeted viral nanoparticles as tools for imaging cancer / Choi-Fong Cho [and five others].

Summary: This book reviews the latest research on the molecules and mechanisms of marine host stress responses to viral infections and tumorigenesis. It offers an overview of the state of the art in the field as well as future directions. Metabolism disorder is a characteristic of tumorigenesis. Since viruses complete their life cycle in host cells, such infections cause metabolic disorders in the host. As such, the mechanisms of virus pathogenesis and tumor progression are similar or even identical. In essence, the role of antiviral molecules is to maintain the metabolic homeostasis of infected host cells, and the antiviral molecules induced by virus infection may play an important role in antitumor pathways, resulting in cancer cell death or restoring the disordered metabolism of cancer cells. The molecules generated during host stress responses to viruses can also contribute to the antitumor mechanisms in humans. However, the relationship between host stress responses to virus infection and tumorigenesis has not been extensively explored. In recent years, studies have shown that marine host stress responses to viral invasion can be good models for exploring human antitumor mechanisms. Stimulating further research in the field, this book offers graduate students and researchers with comprehensive insights into host stress responses to viral invasion and tumor progression. It is also a valuable resource for those working in the pharmaceutical industry interested in drug discovery based on molecules derived from host stress responses to viral infection.

Contents:
Intro; Contents;
Chapter 1: Overview of Virus Infection and Tumorigenesis; 1.1 The Significance of Virus in the Ocean; 1.2 Roles of Bacteriophages in the Extreme Environment; 1.3 Virus Infection and Host Metabolism; 1.3.1 Virus Infection and Host Glucose Metabolism; 1.3.2 Virus Infection and Host Lipid Metabolism; 1.3.3 Virus Infection and Host Nucleic Acid Metabolism; 1.3.4 Virus Infection and Host Vitamin Metabolism; 1.4 Cancer and Metabolism; 1.5 Antiviral Stress Responses of Marine Organisms and Antitumor of Human Being 1.5.1 The Roles of miRNAs Derived from Shrimp Stress Responses to Virus Infection in Human Tumorigenesis1.5.2 Effects of Metabolites from Bacterial Stress Response to Bacteriophage Infection on Tumorigenesis; 1.6 Brief Description of the Book; References;
Chapter 2: Marine Viruses; 2.1 Overview of Marine Viruses; 2.1.1 What Are Marine Viruses?; 2.1.2 Progress of Marine Virology; 2.1.3 Progress of Deep-Sea Virology; 2.2 Diversity and Abundance of Marine Viruses; 2.2.1 Abundance of Marine Viruses; 2.2.2 Marine Virus Taxonomy; 2.2.3 Diversity of Deep-Sea Viruses 2.3 The Interactions Between Marine Viruses and Their Hosts2.3.1 The Influence of Marine Phage-Mediated Lysis of Their Hosts on Microbial Community Structure; 2.3.2 The Effects of Marine Phages on the Hosts' Diversity and Metabolism by Lysogeny; 2.3.3 Benefits of Marine Phage on Its Hosts; 2.4 The Roles of Marine Viruses in Global Ecosystems and Climate Changes; 2.4.1 The Roles of Marine Viruses in Global Nutrient and Biogeochemical Cycles; 2.4.2 The Roles of Marine Viruses in Global Climate Changes; 2.5 Summary; References;
Chapter 3: Marine Invertebrate Stress Responses to Virus Infection 3.1 Different Kinds of Stress Responses of Marine Invertebrates3.1.1 The Process of Stress Response; 3.1.2 The Proteins Involved in Stress Response; 3.1.3 Marine Invertebrates; 3.1.4 The Types of Stress Responses in Marine Invertebrates; 3.1.5 The Relationship Between Innate Immunity and Stress Responses in Invertebrates; 3.1.6 Diseases and Stress Responses of Marine Invertebrates; 3.2 Stress Responses of Arthropods; 3.2.1 Stress Responses of Shrimp; Humoral Responses; Crab; Chemicals; Salinity; Unsaturated Fatty Acid; Heavy Metals; Temperature; Physiological Damage; Virus 3.3 Response of Mollusca to Pathogen Invasion3.3.1 Overview of Marine Molluscs; 3.3.2 Stress Response of Molluscs to Pathogen Infection; 3.4 Stress Response of Echinodermata to Pathogen Infection; 3.4.1 Classification and Distribution of Marine Echinoderms; 3.4.2 Diseases and Pathogens of Marine Echinoderms; 3.4.3 Echinoderm Immune Responses to Pathogens; 3.5 Stress Response of Other Marine Invertebrates; 3.6 Summary; References;
Chapter 4: The Roles of MicroRNAs in Antiviral Immunity of Marine Invertebrates; 4.1 The Immune System of Marine Invertebrates

Contents:
Virus-like particles in vaccine development / Franco M. Buonaguro & Luigi Buonaguro
Developments in virus-like particle-based vaccines for HIV / Luigi Buonaguro, Maria Tagliamonte, Maria Luisa Visciano, Maria Lina Tornesello & Franco M Buonaguro
Virus-like particle vaccines for the prevention of human papillomavirus infection / Joshua W. Wang, Richard B.S. Roden, Maria Lina Tornesello & Franco M. Buonaguro
Virus-like particle-based vaccines against hepatitis C virus infection / Bertrand Bellier & David Klatzmann
Evaluation of human rotavirus VLP vaccines in neonatal gnotobiotic pigs / Marli P. Azevedo, Anastasia N. Vlasova & Linda J. Saif
Presenting heterologous epitopes with hepatitis B core-based virus-like particles / Sarah De Baets, Kenny Roose, Bert Schepens & Xavier Saelens
SV40 virus-like particles as an effective delivery system and a vaccine platform / Masaaki Kawano, Masanori Matsui & Hiroshi Handa
Plant-produced virus-like particle vaccines / Nunzia Scotti & Edward P. Rybicki
Production of complex virus-like particles in insect cells / Fabiana Fernandes, Ana P. Teixeira, Nuno Carinhas, Manuel J.T. Carrondo & Paula M. Alves
Index.

Summary: Viruses: From Understanding to Investigation provides students with a map for lifetime learning by presenting the definition and unique characteristics of viruses, including major topics, such as the virus lifecycle, structure, taxonomy, evolution, history, host-virus interactions and methods to study viruses. In addition, the book assesses the connections between, and among, the aforementioned topics, providing an integrated approach and in-depth understanding of how viruses work.

Summary: Viruses: Molecular Biology, Host Interactions, and Applications to Biotechnology provides an up-to-date introduction to human, animal and plant viruses within the context of recent advances in high-throughput sequencing that have demonstrated that viruses are vastly greater and more diverse than previously recognized. It covers discoveries such as the Mimivirus and its virophage which have stimulated new discussions on the definition of viruses, their place in the current view, and their inherent and derived 'interactomics' as defined by the molecules and the processes by which virus gene products interact with themselves and their host's cellular gene products. Further, the book includes perspectives on basic aspects of virology, including the structure of viruses, the organization of their genomes, and basic strategies in replication and expression, emphasizing the diversity and versatility of viruses, how they cause disease and how their hosts react to such disease, and exploring developments in the field of host-microbe interactions in recent years. The book is likely to appeal, and be useful, to a wide audience that includes students, academics and researchers studying the molecular biology and applications of viruses.

Summary: "Here, my previous edition of Viruses, Plagues, & History is updated to reflect both progress and disappointment since that publication. This edition describes newcomers to the range of human infections, specifically, plagues that play important roles in this 21st century. The first is Middle East Respiratory Syndrome (MERS), an infection related to Sudden Acute Respiratory Syndrome (SARS). SARS was the first new-found plague of this century. Zika virus, which is similar to yellow fever virus in being transmitted by mosquitos, is another of the recent scourges. Zika appearing for the first time in the Americas is associated with birth defects and a paralytic condition in adults. Lastly, illness due to hepatitis viruses were observed prominently during the second World War initially associated with blood transfusions and vaccine inoculations. Since then, hepatitis virus infections have afflicted millions of individuals, in some leading to an acute fulminating liver disease or more often to a life-long persistent infection. A subset of those infected has developed liver cancer. However, in a triumph of medical treatments for infectious diseases, pharmaceuticals have been developed whose use virtually eliminates such maladies. For example, Hepatitis C virus infection has been eliminated from almost all (>97%) of its victims. This incredible result was the by-product of basic research in virology as well as cell and molecular biology during which intelligent drugs were designed to block events in the hepatitis virus life-cycle"-- Provided by publisher.

Contents:
Author's note: Covid-19
Viruses, plagues, and history. A general introduction
Introduction to the principles of virology
Introduction to the principles of immunology
Success stories. Smallpox : the geopolitical impact of smallpox
Yellow fever
Measles virus
Poliomyelitis
Hepatitis viruses : oysters, blood transfusions, and cancer
Present and future challenges. An overview of newly emerging viral plagues : the hemorrhagic fevers and a newly mysterious suspect of viral disease, acute flaccid paralysis
Lassa fever
Ebola
Hantavirus
Severe acute respiratory syndrome, the first pandemic of the twenty-first century; Middle east respiratory syndrome; and the 2019-2020 outbreak of 2019-nCoV
West Nile virus : deaths of crows and humans
Zika comes to the western hemisphere and Americas : how, when, consequences
Human immunodeficiency virus : AIDS, the current plague
Mad cow disease and Englishmen : dementia of humans, prions : folding protein transmissible diseases
Influenza virus, the plague that will continue to return
Apathy and ignorance : false prophets of autism and the anti-vaccine movement
Conclusions and future predictions.

Contents:
Human Cancer Virology: An Historical Review
Epstein-Barr Virus: Pathogenesis and Host Immune Response
Epstein-Barr Virus: Epidemiology and Clinical Features of Related Cancer
Hepatitis C Virus: Pathogenesis and Host Immune Response
Hepatitis C Virus: Epidemiology and Clinical Features of Related Cancer
Hepatitis B Virus: Pathogenesis and Host Immune Response
Hepatitis B Virus: Epidemiology and Clinical Features of Related Cancer
Human Papillomavirus: Pathogenesis and Host Immune Response
Human Papillomavirus: Epidemiology and Clinical Features of Related Cancer
Human T-Cell Leukemia Virus Type 1: Pathogenesis and Host Immune Response
Human T-Cell Leukemia Virus Type 1: Epidemiology and Clinical Features of Related Cancer
Kaposi's Sarcoma-Associated Herpesvirus: Pathogenesis and Host Immune Response
Kaposi's Sarcoma-Associated Herpesvirus: Epidemiology and Clinical Features of Related Cancer
Merkel Cell Polyomavirus: Pathogenesis and Host Immune Response
Merkel Cell Polyomavirus: Epidemiology and Clinical Features of Related Cancer.

Summary: Research on oncogenic viruses and related human cancers has advanced rapidly in the past decade. Most articles, however, focus on a specific oncogenic virus and cancer. There is consequently a need for a comprehensive, up-to-date monograph that offers broad and integrated knowledge. Viruses and Human Cancer - From Basic Science to Clinical Prevention is designed to meet this need by providing an advanced overview on the basic and clinical aspects of oncogenic viruses and the human cancers that they cause. Virology, virus-induced inflammation and tissue injuries, oncogenic mechanisms, epidemiology, and current and emerging preventive and therapeutic strategies are all discussed in detail. In addition, the book covers the individual aspects of seven oncogenic viruses, i.e., hepatitis B virus, hepatitis C virus, human papilloma virus, Epstein-Barr virus, human T-cell lymphotropic virus, Kaposi sarcoma-associated herpes virus, and Merkel cell polyomavirus, and the related human cancers. The susceptibility of high-risk hosts such as transplantation recipients is also addressed, and new vaccine developments are described.

Contents:
Virus infection and human cancer An overview
Epidemiology of virus infection and human cancer
Viral oncogenes and human cancer
Virus infection, inflammation and cancer prevention
The oncogenic role of hepatitis B virus
Prevention of hepatitis B virus infection and liver cancer
The oncogenic role of hepatitis C virus
Prevention of hepatitis C virus infection and liver cancer
The oncogenic role of Human Papilloma virus
Prevention of Human Papilloma virus and related cancers
The oncogenic role of Epstein-Barr virus
Prevention of Epstein-Barr virus infection and related cancers.- The oncogenic role of Human T-Cell Lymphotropic virus
Prevention of Human T-Cell Lymphotropic virus infection and adult T-Cell leukemia
The oncogenic role of Kaposi sarcoma-associated herpes virus (HHV-8).- Prevention of Kaposi sarcoma-associated herpes virus (HHV-8) and Kaposi s sarcoma.- Merkel cell polyomavirus (MCV) and human Merkel cell carcinoma.- Infection-associated cancer after transplantation Prevention and cure.- Viral infection and cancer prevention Future prospects.

Summary: This book, in a new, extensively updated edition, covers viral infection, virus-induced inflammation and tissue injuries, viral epidemiology, oncogenic mechanisms, and current and emerging preventive and therapeutic strategies in detail. Readers will also find information on the individual aspects of a number of oncogenic viruses, including hepatitis B, hepatitis C, human papillomavirus, Epstein-Barr virus, human T-cell lymphotropic virus, Kaposi sarcoma-associated herpes, and Merkel cell polyomavirus, as well as associated human cancers. The book will benefit all those who are seeking a comprehensive, up-to-date overview of the basic and clinical aspects of oncogenic viruses and associated human cancers. Following its original publication in 2014, the first edition of this book quickly became an influential text in the field. This second edition duly reflects the significant advances in knowledge and research that have been achieved in the years since.

Contents:
Virus infection and human cancer - An overview
Epidemiology of virus infection and human cancer
Viral oncogenes and human cancer
Virus infection, inflammation and cancer prevention
The oncogenic role of hepatitis B virus
Prevention of hepatitis B virus infection and liver cancer
The oncogenic role of hepatitis C virus
Prevention of hepatitis C virus infection and liver cancer
The oncogenic role of Human Papilloma virus
Prevention of Human Papilloma virus and related cancers
The oncogenic role of Epstein-Barr virus
Prevention of Epstein-Barr virus infection and related cancers
The oncogenic role of Human T-Cell Lymphotropic virus
Prevention of Human T-Cell Lymphotropic virus infection and adult T-Cell leukemia
The oncogenic role of Kaposi sarcoma-associated herpes virus (HHV-8)
Prevention of Kaposi sarcoma-associated herpes virus (HHV-8) and Kaposi's sarcoma
Merkel cell polyomavirus (MCV) and human Merkel cell carcinoma
Infection-associated cancer after transplantation - Prevention and cure
Viral infection and cancer prevention - Future prospects.

Summary: Worldwide, infectious disease remains a major cause of morbidity and mortality. In developing countries, infection accounts for a substantial proportion of all recorded deaths. Likewise, in developed countries, pneumonia alone results in a large number of deaths. Along with bacteria, parasites and rickettsial organisms, viruses are responsible for many of the infections afflicting the human host. In the past decade alone, viruses that primarily target the lung have caused major respiratory illnesses including outbreaks of severe adult respiratory distress syndrome (SARS) and H1N1 influenza. This book is distinctive in that the entire spectrum of viral disease of the lung is conveniently compiled within a single volume. The epidemiologic, ultrastructural, immunologic, clinical and histopathologic features of well-known viral pathogens and newer emergent infectious agents are discussed. The book is organized in a classic fashion, starting with introductory material and sections on lung defenses and the taxonomic classification of pneumotropic viruses. The various acute viral pneumonias are then considered in a standard format in the main body of the book. Subsequent sections are devoted to the human immunodeficiency virus, viral lung disease in children and other viral-linked tumoral and nontumoral lung conditions. A chapter is also included on animal lung diseases caused by viruses. The text is supplemented by numerous color images.

Summary: This book shows how new technologies and technical skills together with deeper understanding of pathophysiology of visceral and renal ischemia have contributed to significant improvements in the clinical outcomes in patients undergoing complex aortic repair involving splanchnic arteries. In recent years, aortic repair has expanded its borders, focusing more and more on the particularly challenging segments from which critical branches originate. Optimal results in this area are obtained through a multidisciplinary approach based on crucial elements such as sophisticated imaging techniques, advanced anesthesiological and pharmacological strategies, as well as updated surgical techniques and devices able to reduce ischemic injuries. The book presents problems tackled from different perspectives, by analyzing the main technical aspects of the surgical technique but also functional and metabolic issues. It also discusses concepts such as ischemic preconditioning and ischemia-reperfusion mechanisms, as well as innovative investigational approaches. In the "endovascular era", it highlights the most recent updates in complex endovascular repair involving renal and visceral arteries, providing both practical tips and tricks and outcomes analyses. The volume also addresses specific, rarely reported problems in vascular surgery, including issues in renal transplant, oncologic surgery with involvement of splanchnic arteries and of the vena cava, and use of the deep veins in aortic surgery. This volume represents a powerful tool for both young and experienced operators who wish to approach the complex aortic pathology either by open surgery or through endovascular methods.".

Contents:
Anatomical overview and imaging of the aorta and visceral arteries
Physiopathology and anaesthesiological management of supravisceral aortic clamping
Perioperative renal pharmacological protection during cardiovascular surgery
Renal protection during open aortic surgery with Custodiol solution
Renal artery stenosis associated with aortic disease: timing and outcomes of operative management
Renal arteries anatomic abnormalities during open abdominal aortic repair
Renal transplantation and aortic disease: operative management
Pulsatile perfusion of kidney allografts
Endovascular aortic repair: the renal side of the story
Challenging infrarenal aortic necks in EVAR: devices evolution, long-term results and new concepts
Open repair of pararenal aneurysms: renal vessels surgical management
Endovascular repair of pararenal aortic aneurysms: the management of visceral arteries with fenestrated technology
Emergency kit for chimney technique for ruptured abdominal aortic aneurysm
Current treatment options for complex aortic pathology with visceral arteries involvement between open and endo: single center experience
Aortic "coral reef" with visceral arteries involvement: treatment options
Thoracoabdominal aortic aneurysm open repair: visceral arteries reattachment strategies
Sutureless anastomosis during thoracoabdominal aortic repair
Tissue ischemia during aortic surgery. The point of view of the perfusionist
Ischemic preconditioning: the rationale and evidence based outcomes
Intraoperative neurophysiologic monitoring during aortic surgery: basic principles and clinical experience
Long-term patency of visceral vessels after thoracoabdominal aortic repair
Fate of Carrel patch after thoracoabdominal aortic repair: treatment options for recurrent aneurysms
Total endovascular repair of thoracoabdominal aortic aneurysms: lessons learned
The SpiderGraft for Thoracoabdominal Aortic Repair: rationale and indications
Visceral ischemia during type B dissection: incidence, prognostic value, diagnosis and operative management
Visceral ischemia during acute type B dissection: limits of current approaches and new perspective
Epidemiology, diagnosis and clinical management of arteritis involving visceral vessels
Visceral arteries involvement in Takayasu patients: treatment options
Aortic infection with visceral arteries involvement in the endovascular era: treatment options
Deep vein reconstruction for infective aortic syndromes with visceral arteries involvement
Vena cava oncologic surgery
Rerouting of visceral arteries during hybrid thoracoabdominal aortic repair: a still useful solution in highly selected case.

Summary: "Over the past fifty years, enormous progress has been made in understanding visual mechanisms and treating eye disorders. And yet the scientist is not always aware of the latest clinical advances and the clinician is often not up to date on the basic scientific discoveries. Writing in nontechnical language, John and Joseph Dowling, a neuroscientist and an ophthalmologist, examine vision from both perspectives, providing concise descriptions of basic visual mechanisms and related clinical abnormalities. Thus, an account of the photoreceptors is followed by a consideration of retinitis pigmentosa and macular degeneration; an explanation of the retina's function is followed by details of glaucoma and diabetic retinopathy. The authors begin with the cornea and lens, which project an image on the light-sensitive elements inside the eye, the photoreceptors, and how that process can be compromised by such disorders as cataracts and corneal disease. They go on to describe, among other things, how the photoreceptors capture light; retinal and visual cortical anatomy and physiology; and higher level visual processing that leads to perception. Cortical disorders such as amblyopia are discussed as well as specific deficits such as the inability to recognize faces, colors, or moving objects. Finally, they survey the evolution of our knowledge of vision, and speculate about future advances." -- Publisher's description

Contents:
Visual pathways, eye development, and retinal organization : visual deficits and blindness
Focusing light--cornea and lens : refractive errors, dry eye, and cataracts
Capturing light--the photoreceptors : retinitis pigmentosa and age-related macular degeneration
Analyzing the visual image--the retina : glaucoma and diabetic retinopathy
Beyond the retina--lateral geniculate nucleus and visual cortex : amblyopia
Higher-level processing and visual perception : blindsight
Looking back and forward.

Summary: This book provides an overview of the research surrounding the relevance of visual factors for those who struggle with reading. Visual interventions that have been advocated as helping with reading include spectacles that simply correct refractive errors (e.g., long-sightedness), coloured overlays (sheets placed on the page) and coloured lenses, vision therapy, and computer games. This book explains the rationale behind these interventions and discusses the evidence supporting them. Clear advice is given in plain English to those wondering if these interventions will be helpful. Vision, Reading Difficulties, and Visual Stress, 2nd Edition draws together disparate research findings in a range of neurological disorders where vision is compromised by cortical hyperexcitability. Optometrists, orthoptists, ophthalmologists, educational psychologists, teachers, and vision scientists will find this book to be an interesting resource as well as students in these disciplines and parents of children who struggle with reading.

Contents:
Intro
Dedication
Preface
Acknowledgment
Disclosures
Contents
Chapter 1 Introduction
Chapter 2 Refractive errors & ocular health
Chapter 3 Binocular vision and accommodative anomalies
Chapter 4 Eye movements, dominant eye, behavioral optometry, balance and cerebro-vestibular treatments
Chapter 5 The magnocellular-dorsal (M-D) deficit and associated theories
Chapter 6 Coloured filters
early studies
Chapter 7 Do coloured filters work?
Chapter 8 How do coloured filters work?
Chapter 9 Coloured filters: clinical tools
Chapter 10 Clinical protocol Chapter 11 Other potential uses of precision tints
Chapter 12 Research priorities and practice
Appendices
Appendix 1: Guidance for eye care professionals concerning publicity on dyslexia, visual stress, and related conditions
Appendix 2: Information to help publishers
Appendix 3: Additional resources
Index

Contents:
Introduction
Functional Organization of the Visual System
Part I: Development of the Visual System
Development of Visual Capabilities
Anatomical Development of the Visual System
Development of Receptive Field Properties
Part II: Amblyopia and the Effects of Visual Deprivation
Modifications to the Visual Input that lead to Nervous System changes
Known Physiological and Anatomical changes from optical and motor deficits
What is Amblyopia?
Critical Periods
Treatment of Amblyopia
Part III: Mechanisms of Plasticity
Concepts of Plasticity
Mechanisms of Plasticity in the Visual Cortex
Deprivation Myopia and Emmetropization
Index.

Summary: "The Visual Guide to Neonatal Cardiology is a comprehensive, highly illustrated, reference covering the evaluation, diagnosis and management of cardiac disease in the newborn. Contains over 900 color illustrations, including patient photographs, chest roentgenograms, electrocardiograms, echocardiograms, angiocardiograms, 3D computed tomogramphy, magnetic resonance imaging, pathologic specimens, and other relevant visual aids Discusses the natural history of fetal heart disease and the rationale, indications, technique, and impact of fetal cardiac intervention Reviews the anatomy and physiology of the neonatal cardiovascular system, including differences within the fetal, transitional, neonatal, child and adult circulatory system Highlights key steps for taking a patient history, including detailed discussion of the cardiac examination (inspection, palpation and auscultation of heart sounds and murmurs) Presents over 35 morphologic conditions with sections covering introduction, epidemiology, etiology with accepted or postulated embryogenesis, pathophysiology, clinical presentation, physical examination findings, diagnostic evaluation, management, and prognosis Includes a neonatal formulary reviewing selected medications currently used for treatment of perioperative low cardiac output, congestive heart failure, pulmonary hypertension, sedation, pain and anticoagulation in neonates"--Provided by publisher.

Contents:
1. Brief Overview of Scleroderma: Localized Scleroderma and Systemic Sclerosis (SSc) / Maureen D. Mayes
2. Localized Scleroderma / Carolyn A. Bangert, Andrew Kim, and Heidi Jacobe
3. Skin Manifestations and Musculoskeletal Disease in SSc / Janet Pope and Maureen D. Mayes
4. Nailfold Capillaroscopy / Michael Hughes and Ariane L. Herrick
5. Ischemic Digital Ulcers / Fredrick M. Wigley
6. Lung Involvement in Systemic Sclerosis / John T. Huggins, James G. Ravenel, and Richard M. Silver
7. Gastrointestinal Involvement in Systemic Sclerosis / Dinesh Khanna, Jason Baker, Philip J. Clements, and Christopher P. Denton
8. Calcinosis Cutis in Systemic Sclerosis / Gloria A. Salazar and Maureen D. Mayes
9. Systemic Sclerosis Mimics / Gloria A. Salazar, Virginia D. Steen, and Maureen D. Mayes.

Summary: For the millions of people with untreatable blindness the thought of a visual prosthesis that would allow them to live a normal life has always been a distant hope. There have been intermittent bright spots that periodically fan that hope such as when Dr. Dobelles visual prosthesis patient drove a car in an empty parking lot. This book will serve as an update of the work in developing a visual prosthesis. Chapters discuss the physiologic and engineering issues, alternative strategies, and patents, as well as recent research studies. Visual Prosthesis - A Concise Guide is a must-have resource for ophthalmologists, neurologists, engineers and physicists.

Contents:
Chapter 1. Blindness
Chapter 2. Anatomy of the Visual System
Chapter 3. History
Chapter 4. Questions
Chapter 5. Cortical Visual Prosthesis Studies
Chapter 6. Retinal Implant Studies
Chapter 7. Other Projects
Chapter 8. Visual Prosthesis Patents
Chapter 9. Noninvasive Brain Treatment Modalities
Chapter 10. References.

Contents:
Chapter One. RNA Imaging with Multiplexed Error-Robust Fluorescence In Situ Hybridization (MERFISH) / J.R. Moffitt, X. Zhuang
Chapter Two. Imaging Single mRNA Dynamics in Live Neurons and Brains / H.C. Moon, H.Y. Park
Chapter Three. Monitoring of RNA Dynamics in Living Cells Using PUM-HD and Fluorescent Protein Reconstitution Technique / H. Yoshimura, T. Ozawa
Chapter Four. Applications of Hairpin DNA-Functionalized Gold Nanoparticles for Imaging mRNA in Living Cells / S.R. Jackson, A.C. Wong, A.R. Travis, I.E. Catrina, D.P. Bratu, D.W. Wright, A. Jayagopal
Chapter Five. In Vivo RNA Visualization in Plants Using MS2 Tagging / E.J. Peña, M. Heinlein
Chapter Six. TRICK: A Single-Molecule Method for Imaging the First Round of Translation in Living Cells and Animals / J.M. Halstead, J.H. Wilbertz, F. Wippich, T. Lionnet, A. Ephrussi, J.A. Chao
Chapter Seven. Fluctuation Analysis: Dissecting Transcriptional Kinetics with Signal Theory / A. Coulon, D.R. Larson
Chapter Eight. IMAGEtags: Quantifying mRNA Transcription in Real Time with Multiaptamer Reporters / J. Ray, I. Shin, M. Ilgu, L. Bendickson, V. Gupta, G.A. Kraus, M. Nilsen-Hamilton
Chapter Nine. A Method for Expressing and Imaging Abundant, Stable, Circular RNAs In Vivo Using tRNA Splicing / C.A. Schmidt, J.J. Noto, G.S. Filonov, A.G. Matera
Chapter Ten. RNA-ID, a Powerful Tool for Identifying and Characterizing Regulatory Sequences / C.E. Brule, K.M. Dean, E.J. Grayhack
Chapter Eleven. Fluorescent Protein-Based Quantification of Alternative Splicing of a Target Cassette Exon in Mammalian Cells / N.G. Gurskaya, D.B. Staroverov, K.A. Lukyanov
Chapter Twelve. IRAS: High-Throughput Identification of Novel Alternative Splicing Regulators / S. Zheng
Chapter Thirteen. Analysis of Nonsense-Mediated mRNA Decay at the Single-Cell Level Using Two Fluorescent Proteins / N.G. Gurskaya, A.P. Pereverzev, D.B. Staroverov, N.M. Markina, K.A. Lukyanov
Chapter Fourteen. Developing Fluorogenic Riboswitches for Imaging Metabolite Concentration Dynamics in Bacterial Cells / J.L. Litke, M. You, S.R. Jaffrey.

Contents:
Preface / Tara Mahfoud, Sam McLean and Nikolas Rose
Vital brains: on the entanglement of media, minds, and models / Cornelius Borck
Slicing the cortex to study mental illness: Alois Alzheimer's pictures of equivalence / Lara Keuck
Opaque models: using drugs and dreams to explore the neurobiological basis of mental phenomena / Nicolas Langlitz
Man not a machine: models, minds, and mental labor, c.1980 / Max Stadler
Infrastructural intelligence: contemporary entanglements of neuroscience and AI / Johannes Bruder
Learning from large-scale neural simulations / Maria Serban
Connectomes as constitutively epistemic objects: critical perspectives on modeling in current neuroanatomy / Philipp Haueis, Jan Slaby
Bridging the gap between system and cell: the role of ultra-high field MRI in human neuroscience / Robert Turner, Daniel De Haan.

Summary: This book presents the scientific evidence for the role of vitamin C in health and disease and offers new guidance on vitamin C intake in humans. The importance of vitamin C in preventing cancer and cardiovascular disease, its relevance to aging and stress, and its impacts on each of the human body systems are thoroughly assessed on the basis of the authors extensive research and his deep understanding, as an anatomy professor, of the body as a whole. Findings published in the international scientific literature are fully taken into account, and due consideration is also given to empirical evidence, bearing in mind that mechanisms of action cannot always be precisely defined in the absence of human experiments. Beyond providing an up-to-date scientific perspective on the effects of vitamin C, the author hopes to promote human health worldwide by encouraging proper use of the vitamin. To this end, recommendations are made on the amount of vitamin C that should be taken daily and on the best way to take it. The book will be of interest to researchers, clinicians, and all others who wish to learn more about this vitamin and its significance.

Contents:
Intro; Preface; Contents;
Chapter 1: Introduction; History of Vitamin C Discovery; What Is Vitamin C?; Brief Explanation of the Biochemical Properties of Vitamin C; Copenhagen Report; Other Biological Activities of Vitamin C Besides Its Roles as an Antioxidant; Sodium-Dependent Vitamin C Transporters (SVCTs); Pharmacokinetics of Vitamin C; Scientific Background on the Recommended Daily Allowance (RDA) of Vitamin C; How to Take Vitamin C; Adverse Effects of Vitamin C; References;
Chapter 2: Cardiovascular System; Cardiovascular System; Heart; Arteries and Veins; Blood Pressure Atherosclerotic Vascular DiseasesPathogenesis of Atherosclerotic Disease; Vitamin C and Nitric Oxide (NO); French Paradox; Scientific Background on the Potential Beneficial Effects of Vitamin C on the Prevention of Atherosclerotic Vascular Diseases; Review of Epidemiological Studies on Relationship Between Vitamin C and Atherosclerotic Vascular Diseases; Relation Between the Plasma Vitamin C Level and Atherosclerotic Vascular Diseases; Relation Between Oral Intake of Vitamin C and Atherosclerotic Diseases Hints from Worldwide Longevity VillagesReferences;
Chapter 8: Stress; Body Responses to Stress; Role of Vitamin C in the Production of the Stress Hormones; Stress and Health; Utilization of Stress; Vitamin C and Disease and Death; References;
Chapter 9: Digestive System; Gastrointestinal (GI) Tract; Associated Digestive Glands; Nitrosamine, a Possible Carcinogen, H. pylori, and Vitamin C; SVCT1 and Small Intestine; The Colon and Vitamin C; Vitamin C and Acute Pancreatitis; References;
Chapter 10: Liver; Blood Supply System to the Liver; Liver and Immune System; Vitamin C and Liver Diseases Role of Vitamin C in the Protection of Blood Vessels from Damage by Exercise for Health PromotionReferences;
Chapter 3: Cancer; Causes of Cancer Formation; Treatment Modalities for Cancer; Review of the Anticancer Effects of Vitamin C; Mechanisms Involved in Tumor Cell Killing by Vitamin C; Suggestions; References;
Chapter 4: Immune System; Non-specific Immune System; Specific Immune System; Link Between the Innate and Adaptive Immune Systems; Vitamin C and B Lymphocytes; Vitamin C and T Lymphocytes; Vitamin C and NK Cells; Vitamin C and Other Immune Cells Involved in Innate Immunity

Contents:
Young Woman with Vitamin D Deficiency
Vitamin D Deficiency in Infants
Vitamin D Deficiency in Cystic Fibrosis
Vitamin D Deficiency in Anorexia Nervosa
Vitamin D Deficiency Following Bariatric Surgery
Vitamin D in Postsurgical Hypoparathyroidism
Vitamin D in Patients with Hypoparathyroidism/Hypocalcemia
Vitamin D in Disorders of Phosphorus
Vitamin D in Disorders of Vitamin D Action: Vitamin D Dependent Rickets Type I
Vitamin D Deficiency in Chronic Kidney Disease
Vitamin D in Psoriasis.

Summary: "Vitamin D: Volume One: Biochemistry, Physiology and Diagnostics, Fourth Edition, presents the latest information from international experts in endocrinology, bone biology and human physiology, taking readers through the basic research of vitamin D. This impressive reference presents a comprehensive review of the multifaceted vitamin D. Researchers from all areas will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted genomic and proteomic insights on the mechanisms of disease. Offers a comprehensive reference, ranging from basic bone biology, to biochemistry, to the clinical diagnostic and management implications of vitamin DSaves researchers and clinicians time in quickly accessing the very latest details on the diverse scientific and clinical aspects of Vitamin D, as opposed to searching through thousands of journal articlesTargets chemistry, metabolism and circulation, mechanisms of action, mineral and bone homeostasis, human physiology, diagnosis and management, nutrition, sunlight, genetics and vitamin D deficiency. Volume II of this collection presents a clinical focus on disorders, analogs, cancer; immunity, inflammation and disease and therapeutic applications"--Publisher's description.

Contents:
Section I: History, chemistry metabolism, circulation & regulation. Historical overview of vitamin d
Evolutionary biology: mysteries of vitamin D in fish
Evolution of human skin color and vitamin D
Photobiology of vitamin D
The activating enzymes of vitamin D metabolism (25- and 1[alpha]-hydroxylases)
CYP24A1: structure, function, and physiological role
The vitamin D binding protein DBP
Regulation of renal and extra-renal 1[alpha]-hydroxylase
Section II. Mechanism of action. Genome-wide perspectives on vitamin D receptor-meditated control of gene expression in target cells
Diverse mechanisms of transcriptional regulation by the vitamin D receptor
Structural basis for ligand activity in VDR
Ligand independent actions of vitamin D receptor
Vitamin D and chromatin
Mesenchymal differentiation, epigenetic dynamics, and interactions with VDR
Vitamin D and microRNAs
Vitamin D sterol/VDR conformational dynamics and nongenomic actions
Section III. Mineral and bone homeostasis. Vitamin D regulation of osteoblast function
Osteoclastogenesis and vitamin D
Vitamin D activities in osteocytes
Regulation of intestinal calcium and phosphate absorption
Calbindin-D28K and calbindin-D9K and the epithelial calcium channels TRPV5 and TRPV6
Calcium homeostasis and eggshell biomineralization in female chicken
Mineralization in mammals
Cartilage
Vitamin D and bone: an integrated approach
Section IV. Extra-skeletal targets. Vitamin D and the kidney
Vitamin D and the parathyroids
The calcium-sensing receptor and vitamin d
Vitamin D in dentoalveolar and oral health
The role of vitamin D and its receptor in hair follicle biology
Vitamin D, calcium and the epidermis
Vitamin D and the cardiovascular system
Vitamin D brain development and function
Vitamin D, VDR and adipose tissue: focus on cellular mechanisms
Vitamin D and skeletal muscle
Understanding vitamin D from mouse knockout models
Section V. Human physiology. Pharmacology and pharmacokinetics
Vitamin D role in the calcium and phosphorus economies
Fetus, neonate and infant
Consequences of perinatal vitamin D deficiency on later bone health
Adolescence and acquisition of peak bone mass
Pregnancy, lactation, and post-weaning recovery
Role in reproductive biology and reproductive dysfunction in women
Vitamin d, reproductive biology, and dysfunction in men
Vitamin D and the renin-angiotensin system
Parathyroid hormone, parathyroid hormone-related protein, and calcitonin
FGF23 counter regulatory hormone for vitamin D actions on mineral metabolism, hemodynamics, and innate immunity
Section VI. Diagnosis and management. Approach to the patient with metabolic bone disease
Detection of 1,25-dihydroxyvitamin D in human serum using receptor assisted chemiluminescent hormone assay (REACH) technology
Mass spectrometry assays of vitamin D metabolites
Free vitamin d: concepts, assays, outcomes and prospects
25-hydroxyvitamin D assays: standardization guidelines, problems and interpretation
Bone histomorphometry
Radiology of rickets and osteomalcia
High-resolution imaging techniques for bone quality assessment
The role of vitamin D in orthopedic surgery
The IOM-Endocrine Society controversy on recommended vitamin D targets: in support of the IOM Position
The IOM-Endocrine Society controversy on recommended vitamin D targets: in support of the endocrine society position

Summary: "Vitamin D: Volume 2: Health, Disease and Therapeutics, Fourth Edition, authoritatively covers the evidence for new roles for vitamin D, ranging from cardiovascular disease, to cancer, diabetes, inflammatory bowel disease, multiple sclerosis and renal disease. This collection represents a who's who of vitamin D research and the coverage is appropriately broad, drawing in internal medicine, orthopedics, oncology and immunology. Clinical researchers will gain a strong understanding of the molecular basis for a particular area of focus"--Publisher's description.

Contents:
Section VII. Population studies: vitamin D deficiency, nutrition, sunlight, genes & trials. Methods of evaluating population studies of vitamin d: strengths & weaknesses
Worldwide vitamin D status
Vitamin D in foods: an evolution of knowledge
Determinants of vitamin D deficiency from sun exposure: a global perspective
Vitamin D fortification and supplementation policies to correct vitamin D insufficiency/deficiency globally
Vitamin D and food fortification
Bariatric surgery, vitamin D, and bone loss
Genetics of the vitamin D endocrine system
Randomized clinical trials of vitamin D for the primary prevention of cancer and cardiovascular disease, with a focus on the VITamin D and OmegA-3 TriaL (VITAL)
Section VIII. Disorders. Vitamin D deficiency and nutritional rickets in children
Vitamin D and osteoporosis
Adult vitamin D deficiency: fracture & fall prevention
Clinical disorders of phosphate homeostasis
Vitamin D hydroxylation-deficient rickets, type 1A: CYP27B1 mutations
Hereditary 1,25-dihydroxyvitamin D resistant rickets
The role of genetic variation in CYP2R1, the principal vitamin D 25-hydroxylase, in vitamin D homeostasis
Infantile hypercalcemia and CYP24A1 mutations
Drug and hormone effects on vitamin D metabolism
Vitamin D and organ transplantation
The role of vitamin D in type 2 diabetes and hypertension
Vitamin D, obesity and the metabolic syndrome
Vitamin D and renal disease
Calcitriol and analogs in the treatment of chronic kidney disease
Idiopathic hypercalciuria and nephrolithiasis
Hypercalcemia due to vitamin D toxicity
The hypocalcemic disorders
Vitamin d: cardiovascular effects and vascular calcification
Vitamin D and Paget's disease
Section IX. Vitamin D analogs. Analogs of calcitriol
Non-secosteroidal ligands and modulators of VDR
Bile acid-derived vitamin D receptor ligands
Bifunctional vitamin D hybrid molecules
Modulating vitamin D receptor-coregulator binding with small molecules
Extended-release calcifediol in renal disease
Vitamin D receptor antagonists
Eldecalcitol and osteoporosis
Section X. Vitamin D and cancer. Overview of vitamin D actions in cancer
Vitamin D status and cancer incidence, mortality and prognosis
Effects of vitamin D derivatives on differentiation, cell cycle and apoptosis in hematological malignancies
Vitamin D actions in mammary gland and breast cancer: genomics, metabolism and stem cells
Vitamin D urologic cancers
Vitamin D and colon cancer
Vitamin D and skin cancer
Vitamin D and lung cancer
Vitamin D inflammation and cancer
Section XI. Immunity, inflammation and disease. Vitamin D and tuberculosis
Vitamin D and adaptive immunology in health and disease
Vitamin D and innate immunity
Vitamin D and diabetes
Vitamin D and multiple sclerosis
Vitamin D and inflammatory bowel disease
Psoriasis and other skin diseases
Section XII. Therapeutic applications and new advances. Sunlight protection by vitamin D compounds
Vitamin D, cardiovascular disease and hypertension
Vitamin D, acute respiratory infection, and asthma/COPD
Vitamin D and muscle performance in athletes
Vitamin d: presence and function in the eye
Adult vitamin D deficiency and adverse brain outcomes
Vitamin D in pregnancy and lactation: moving into the future
Vitamin D and critically ill ICU patients.

Contents:
Part I. Generalities, measurement and epidemiology
Part II. Classical mineral and bone effects
Part III. Non-classical effects of Vitamin D
Part IV. Kidney transplantation
Index.

Contents:
Physiology of the calcium-parathyroid hormone-vitamin D axis / Goltzman, D.; Mannstadt, M.; Marcocci, C.
Vitamin D assays / Bikle, D.D.
Vitamin D-binding protein / Vilaja, T.; Lazaretti-Castro, M.
New concepts in vitamin D requirements for children and adolescents : a controversy revisited / Laing, E.M.; Lewis, R.D.
Practical issues in vitamin D replacement / Adler, R.A.
Extra-skeletal effects of vitamin D / Bouillon, R.
Hypercalcemic states associated with abnormalities of vitamin D metabolism / Jones, G.; Schlingmann, K.-P.
Vitamin D and hypoparathyroidism / Bandeira, L.C.; Rubin, M.R.; Cusano, N.E.; Bilezikian, J.P.
Vitamin D and primary hyperparathyroidism / Walker, M.D.; Bollerslev, J.
Vitamin D and secondary hyperparathyroid states / Cipriani, C.; Pepe, J.; Colangelo, L.; Minisola, S.
Vitamin D and glucocorticoid-induced osteoporosis / Mazziotti, G.; Formenti, A.M.; Frara, S.; Doga, M.; Giustina, A.
Vitamin D and diabetes mellitus / Maddaloni, E.; Cavallari, I.; Napoli, N.; Conte, C.
Vitamin D, sarcopenia and aging / Skaaby, T.; Thuesen, B.H.; Linneberg, A.
Vitamin D homeostasis and diseases in pediatrics / Bianchi, M.L.

Summary: This comprehensive volume examines the role of vitamin E as an essential micronutrient in human health and its extensive clinical benefits. Sections cover a wide breadth of topics, including vitamin E intake and recommended daily allowance, understanding the biological activities of Vitamin E and observed physiological effects, benefits of vitamin E on upper respiratory infections, cardiovascular disease, age-related macular degeneration, Alzheimer's disease, and intake safety. The text serves to emphasize the importance of vitamin E in relation to disease prevention as well as to raise awareness of the number of health conditions where an increased intake of vitamin E can be of potential significance. It explores vitamin E in an up-to-date, science based, applicable real-life perspective and offers pragmatic solutions for its safe and personalized use beyond the various methodological and statistical controversies.

Contents:
[1] Thiamine hydrochloride
[2] Nicotinic acid
[3] Riboflavin
[4] Ascorbic acid
[5] Vitamins.

Summary: Since the first edition of this book was published, new knowledge has been gained on Vitiligo. This widely revised and updated second edition, written by worldwide experts in the field, fully reflects this progress. The apparently, simple and poorly symptomatic presentation of the disease has been a strong disadvantage to its study, as compared to other common chronic skin disorders such as psoriasis and atopic dermatitis. A good skin-based angle of attack is also lacking because generalized Vitiligo is clearly epitomizing the view of skin diseases as simple targets of a systemic unknown dysregulation (diathesis). This view has mostly restricted Vitiligo to the manifestation of an auto-immune diathesis and skin events, which are easily detected using skin biospies in most other situations, have not been precisely recorded, with the argument that a clinical diagnosis was sufficient for the management of the patient with Vitiligo. This richly illustrated second edition reflects the constant international effort to share the information gathered about this disorder at the clinical, pathophysiological and therapeutic levels. Its aim still being to bridge current knowledge at the clinical and investigative level, to point to the many unsolved issues, and to delineate future priorities for research.

Contents:
Preface
I Defining the Disease
1.1 historical aspects
1.2 definitions and classification
1.3 Epidemiology
1.4 Histopathology including electron microscopy
1.5 Clinical aspects Including natural history according to subsets
Short introduction
1.5.1 vitiligo including acrofacial, universalis
1.5.2 segmental vitiligo Including clinical aspects
1.5.3 Mixed vitiligo
1.5.4 rare variants including inflammatory
1.5.5 subtypes of mucocutaneous pigment cell involvement: mucosal, hair follicle (leukotrichia), nevus cells (halo nevus)
1.5.6 extracutaneous melanocytes
1.5.7 Environmental triggers: Koebner phenomenon and occupational vitiligo
1.5.8 associated disorders and comorbidities includingautoimmune/inflammatory disorders, immunodeficiences, rare monogenic diseases
1.5.9 age and vitiligo: childhood, pregnancy, late-onset
1.5.10 vitiligo and skin of colour
1.6 assessment and scoring including QoL
1.7 Editor's synthesis
II Understanding the Disease
2.1 pathophysiology overview
Unifying concepts V-SV
2.2 methods to study vitiligo
2.2.1 in vivo confocal microscopy and other noninvasive techniques
2.2.2 animal models
2.2.3 in vitro
2.3 critical assessment of published data on vitiligo Short introduction
2.3.1 Genetics
2.3.2 epigenetics
2.3.3 melanocyte stability
2.3.4 oxidative stress and intrinsic melanocyte defects
2.3.5 immunity (innate, adaptive). Innate and adaptive separated
2.3.6 peptides, growth factors including POMC and family
2.3.7 Stem cells
2.3.8 other defects and mechanisms
2.4 pathophysiology of segmental vitiligo
2.5 Editor's synthesis
III Treating the Disease
3.1 management overview
What has changed in a therapeutic perspective
3.2 discussion of available and new therapies
3.2.1 medical therapies
3.2.2 phototherapies
3.2.3 surgical therapies
3.2.4 depigmenting therapies
3.3combined/sequential/integrated therapies including maintenance therapy
3.4 camouflage
3.5 photoprotection
3.6 age, gender, ethnic skin, specific locations
3.7 psychological intervention
3.8 patient's perspectives
3.9 discussion of empirical, traditional, alternative approaches
3.10 evidence-based medicine perspective and guidelines
3.11 beyond guidelines
3.12 editor's synthesis and perspectives
Subject Index. .

Summary: This book discusses the newest trends, concepts, and advancements in the management of vitreo-retinal conditions. The field of retina is rapidly changing, with new advances ranging from stem cell therapy, gene therapy and editing, new drug targets, novel delivery systems, and innovative technologies in advanced ocular imaging and surgical techniques. The goal is to provide a way to update practitioners and trainees on how the field of retina is changing. Areas of focus include new technologies, particularly in ocular imaging and vitreo-retinal surgery, major new clinical trials, particularly those that are shifting practice patterns or addressing novel therapies, and novel research that is altering the classification and diagnosis of retinal conditions, as well as management strategies and prognostic predictors for vitreo-retinal diseases. This volume is essential reading for generalist and specialist ophthalmologists and useful for residents and fellows training in various subspecialties.

Contents:
Ocular Imaging
Age-Related Macular Degeneration
Retina in Diabetic Eye Diseases
Retinal and Choroidal Vascular Diseases
Inherited Retinal Diseases and Gene Therapy
Pediatric Retina
Retinal Detachment Surgery
Macular Surgery
1.Surgical Instrumentation and Devices. . .