Books
- The Fabrica of Andreas Vesalius : a worldwide descriptive census, ownership, and annotations of the 1543 and 1555 editions — Fetal cardiology-- a practical approach to diagnosis and management (138)
- Fetal growth restriction : current evidence and clinical practice — Food bioactives and health (138)
- Food biopolymers : structural, functional and nutraceutical properties — Frontiers of hormone research (138)
- Frontiers of neurology and neuroscience — The Future of orthopaedic sports medicine : What should we be worried about? (136)
- DigitalDigital Access Karger v. 9-18, 1998-2016.
- PrintBruce L. Miller, MD.Contents:
History and nomenclature
The clinical syndrome of bvFTD
The clinical syndrome of svPPA
The clinical syndrome of nfvPPA
Related disorders : FTD-ALS
Related disorders : corticobasal degeneration and progressive supranuclear palsy
A primer of FTLD neuropathology
FTD genes
FTD reflections upon psychology and philosophy
Treatments. - DigitalBernardino Ghetti, Emanuele Buratti, Bradley Boeve, Rosa Rademakers, editors.Summary: Under the name of Frontotemporal Dementias (FTD) numerous hereditary and sporadic disorders are listed. FTD may take away speech and language, social skills and ethical judgement, wishes and will, empathy and emotions; it may also impair motor functions. FTD may affect men and women in midlife or during old age leading to the demolition of the uniqueness of the human mind. In the last decade of the 20th century and in the first two decades of the 21st century, progress in the understanding of clinical, neuropathological, biochemical, and genetic aspects of FTD has accelerated. The novel awareness about FTD has directed young generations of researchers toward the study of this complex group of disorders. This Volume has been formulated with the participation of some of the leading scientists who have contributed to the development of knowledge in the clinical and basic science arenas. It captures the current central elements that are relevant to an up-to-date understanding of causes and pathogenesis of multiple forms of FTD. The volume is an opus that represents a distillation of the work of many scientists and addresses the current directions in the study of one of the most complex groups of diseases. In view of its structure, the book could also be used as a textbook, that offers both a broad and deep analysis of major areas in FTD. This book, planned by the International Society for Frontotemporal Dementias, is distinctive as it opens a window to a wide landscape about the biology of FTD. Thus, the book represents a moment of reflection on the present state of our knowledge of FTD and a collective vision toward scientific progress. The authors of each chapter share their knowledge and vision aimed at reducing the suffering which is caused by FTD.
- Print
- DigitalQihui "Jim" Zhai, editor.Summary: The Frozen Section Library series provides concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario. Written by expert surgical pathologists, Frozen Section Library: Endocrine Organs presents common and practical problems including follicular adenoma versus follicular carcinoma, papillary thyroid carcinoma versus reactive change and freezing artifact, follicular variant of papillary thyroid carcinoma, and medullary thyroid carcinoma. Anaplastic carcinoma, thyroid lymphoma, resection margin of a pancreatic endocrine tumor, pheochromocytoma within an adrenal gland and extra- adrenal gland, parathyroid tissue versus a thyroid tissue and versus a lymph node are also explored in detail. All chapters are illustrated with color pictures and accompanied legends. As a handbook for practicing pathologists, this volume is an indispensable aid to diagnosis and for avoiding dangers in one of the most challenging situations that pathologists encounter. Rapid consideration of differential diagnoses and how to avoid traps caused by frozen section artifacts are readily accessible. Tables and charts provide guidance for differential diagnosis of various histological patterns.
Contents:
Thyroid Gland
Parathyroid Gland
Endocrine Tumors of the Pancreas
Adrenal Gland
Pituitary Gland
Paraganglioma
Neuroendocrine Tumors within the Non-Endocrine Organs. - DigitalAlain C. Borczuk, Rhonda K. Yantiss, Brian D. Robinson, Theresa Scognamiglio, Timothy M. D'Alfonso, editors.Summary: This book provides guidance regarding the approach to common scenarios encountered in the frozen section laboratory while underscoring diagnostic pitfalls and providing the proper level of diagnostic information to ensure clear communication. Given the use of frozen section in molecular and research pathology, the text also serves as a guide for morphologic examination. Written by experts in the field, the book is organized according to organ system with additional chapters discussing the roles of digital pathology and molecular assays. Each chapter is extensively illustrated to highlight key points that facilitate interpretation and highlight areas for potential error. The goal of this book is to help trainees understand the need for mastery of this unique diagnostic tool, and to aid pathologists who cover frozen section convert practical information provided into diagnostic improvements. Frozen Section Pathology is a comprehensive and state-of-the-art review and serves as a valuable resource for the general surgical pathologist with frozen section responsibilities as well as surgeons who regularly utilize frozen section.
Contents:
Technique of Intraoperative Consultation
Quality Assurance in Frozen section
Intraoperative Evaluation of the Gastrointestinal Tract
Intraoperative Evaluation of the Liver, Extrahepatic Bile Ducts, Gallbladder, and Pancreas
Head and Neck Pathology
Thyroid and Parathyroid
Frozen Section of Breast and Sentinel Lymph Node
Genitourinary Pathology
Frozen section in lung and pleural pathology
Frozen Sections in Neuropathology
Frozen Section in Gynecologic Pathology
Dermatopathology
Frozen Sections in Bone and Soft Tissue Pathology
Frozen Section and Intraoperative Consultation in Hematopathology
Frozen Sections in Kidney Transplantation
Intra-operative consultation and molecular pathology. - DigitalArvind K. Chavali, Ramesh Ramji, editors.Summary: This book introduces readers to the concept of 'frugal innovation' and describes novel low-cost technologies that aid in diagnosing infectious diseases. Rapidly deployable, portable, and affordable diagnostic tools have the potential to tremendously benefit populations in resource-limited settings and improve global health outcomes. Specifically, the book includes the following features: Cutting-Edge Research: Thorough coverage of scientific advances related to frugal bioengineering that have been developed within the last few years. A few examples of technologies covered in detail include low-cost paper-based and CD-based microfluidic diagnostic systems. Industry and Non-Profit Voices: Chapters written by scientists currently working in industry and philanthropic sectors.Digital Access Springer 2018
- DigitalFernando Freitas de Lima, Caroline Honaiser Lescano, Ivan Pires de Oliveira, editors.Summary: Fruits of the Brazilian Cerrado: Composition and Functional Benefits describes the nutritional, chemical and physical characteristics of the fruits of the Cerrado, as well as their pharmacological effects and use in phytotherapics. Chapters are dedicated to the morphological characteristics, macronutrients, micronutrients and active compounds of various fruits, with separate sections covering their peels, leaves, nuts, pulps, and other components. The text also includes detailed studies on the treatment of diseases with these natural products, as well as their applications in popular use by local communities. Authors explain the importance of bioactive compounds found in the fruits and their possible mechanisms of action in the organism. This text thus provides a valuable reference to researchers studying a range of topics, including functional foods, phytotherapy, and plant science.
Contents:
1. Acrocomia aculeata
2. Attalea dubia & Attalea phalerata
3. Campomanesia genus
4. Caryocar spp
5. Mauritia flexuosa
6. Dipteryx alata
7. Solanum lycocarpum
8. Attalea speciosa
9. Syagrus romanzoffiana
10. Hancornia speciosa. - DigitalVictoria Tepe, Charles M. Peterson, editors.Summary: This ground-breaking title begins with an introductory overview of the Lower Extremity Gait Systems (LEGS) project, identifying concerns and observations as context for the reader to consider topics and challenges detailed in later chapters. Next are chapters that explore relevant military and civilian needs, and an essential historical context of the capabilities and limitations of contemporary prosthetics. The section concludes with an overview of essential components used in passive and active lower limb prosthetics, including sockets, foot, ankle, and knee systems, as well as emerging bionic systems. A second section considers research and development in orthotics, synthetic and biological materials, volitional control, and wearable robotics (also known as exoskeletons). Finally, expert authors explore advanced science and emerging medical perspectives in research related to limb salvage, osseointegration, limb transplantation, and tissue engineering. Designed for medical practitioners, engineers, students, and researchers who use or develop prosthetic technology for civilian or military amputees, Full Stride: Advancing the State of the Art in Lower Extremity Gait Systems will be of great interest to trauma specialists, orthopedists, rehabilitation specialists, nursing staff and physical therapists, as well as researchers and scientists who specialize in fields that shape and inform advanced prosthetic device development such as materials sciences, engineering (electrical, mechanical, biomedical), robotics, and human physiology.Digital Access Springer 2017
- Digitaledited by Alexandru Mihai Grumezescu.Summary: Fullerens, Graphenes and Nanotubes: A Pharmaceutical Approach shows how carbon nanomaterials are used in the pharmaceutical industry. While there are various books on the carbonaceous nanomaterials available on the market, none approach the subject from a pharmaceutical point-of-view. In this context, the book covers different applications of carbonaceous nanomaterials. Chapters examine different types of carbon nanomaterials and explore how they are used in such areas as cancer treatments, pulse sensing and prosthetics. Readers will find this book to be a valuable reference resource for those working in the areas of carbon materials, nanomaterials and pharmaceutical science.Digital Access ScienceDirect 2018
- DigitalDao Wen Wang, editor.Summary: This book provides readers recent advances on basic research and clinical management of fulminant myocarditis. First chapters introduce aetiology, pathology, and pathophysiology of fulminant myocarditis, in which excessive immune activation and subsequent cytokine storm are proposed to be the core pathogenesis. Following chapters present clinical management of fulminant myocarditis, including clinical manifestations, examinations, and diagnosis of fulminant myocarditis, as well as life support-based comprehensive treatment regimen in acute phase.
Contents:
Introduction: Accumulating More Knowledge and Ability in Treating Fulminant Myocarditis to Save More Lives
The Epidemiology of Fulminant Myocarditis
Pattern Recognition Receptors and Fulminant Myocarditis
Etiology and Pathogenesis of Fulminant Myocarditis
Pathophysiology and Mechanisms of Fulminant Myocarditis
Pathology of Fulminant Myocarditis
Clinical Manifestations of and Laboratory Tests for Myocarditis and Fulminant Myocarditis
Diagnostic Values and Clinical Application of Endomyocardial Biopsy in Fulmiant Myocarditis
Association between Histological Changes and Clinical Manifestations of Fulminant Myocarditis
Changes of Electrpcardiography in Patients with Fulminant Myocarditis
Echocardiography in Fulminant Myocarditis
Cardiac Magnetic Resonance in Fulminant Myocarditis
Diagnosis and Differential Diagnosis of Fulminant Myocarditis
Novel Conceptions in Treatments of Fulminant Myocarditis
Treatments of Fulminant Myocarditis in Acute Phase
Prevention and Treatment of Arrhythmias Complicated by Fulminant Myocarditis
Prevention and Treatment of Disseminated Intravascular Coagulation in Fulminant Myocarditis
Rehabilitation Treatment for Myocarditis
Follow-Up and Long-Term Prognosis of Myocarditis and Fulminant Myocarditis
Clinical Nursing for Patients with Fulminant Myocarditis
Introduction of Clinical Courses of Typical Cases of Fulminant Myocarditis (Including Six Cases). - DigitalNeeraj Khanna.Summary: This book provides all the information needed by the dentist in order to understand functional occlusion and describes a coherent method that, through application of principles of form and function, allows the delivery of predictable, natural, and long-lasting aesthetic results. After clear explanation of the concepts of functional aesthetics, functional occlusion, and the envelope of function, the 12 stages of a complete examination are carefully set out, with accompanying rationale. Similarly, full guidance is provided on acquisition of appropriate diagnostic records, comprising perfect impressions, facebow transfer, centric relation bite record, and digital photographs. Further, a method for correct determination of the incisal edge position is presented, with explanation of the importance of this position to aesthetics, function, and phonetics. A step-by-step description of the treatment planning process is then provided, followed by guidance on preparation design and fabrication of restorations. Readers will find the book to be an invaluable aid to attainment of consistent aesthetic results based on stable occlusion.
Contents:
Functional aesthetics
Functional occlusion. Understanding and thinking
The envelope of function: understanding and importance
The complete examination: 12 steps to perform a complete exam
Diagnostic records. What to take and why
Incisal edge position: its importance to aesthetics and function
Phonetics: how to design with phonetics in mind
diagnosis and treatment planning
Communication: with your patients, specialists & technicians
Preparation, planning and quality control.Digital Access Springer 2020 - Digitaledited by Juan C. Stockert, Jesús Espada, Alfonso Blázquez-Castro.Contents:
Predictive binding geometry of ligands to DNA minor groove : isohelicity and hydrogen-bonding pattern / Juan C. Stockert
Using microchip gel electrophoresis to probe DNA-drug binding interactions / Nan Shi and Victor M. Ugaz
Identifying different types of chromatin using Giemsa staining / Juan C. Stockert, Alfonso Blázquez-Castro, and Richard W. Horobin
Analysis of DNA damage and repair by comet fluorescence in situ hybridization (comet-FISH) / Michael Glei and Wiebke Schlörmann
Alkaline nuclear dispersion assays for the determination of DNA damage at the single cell level / Piero Sestili and Carmela Fimognari
Polarization microscopy of extended chromatin fibers / Maria Luiza S. Mello and Benedicto de Campos Vidal
DNA labeling in vivo : quantification of epidermal stem cell chromatin content in whole mouse hair follicles using Fiji image processing software / Elisa Carrasco, María I. Calvo, and Jesús Espada
Historical overview of bromo-substituted DNA and sister chromatid differentiation / Roberto Mezzanotte and Mariella Nieddu
Image analysis of chromatin remodelling / Benedicto de Campos Vidal, Marina B. Felisbino, and Maria Luiza S. Mello
FISH methods in cytogenetic studies / Miguel Pita, Juan Orellana, Paloma Martínez-Rodríguez, Ángel Martínez-Ramírez, Begoña Fernández-Calvín, and José L. Bella
Ultrastructural and immunofluorescent methods for the study of the XY body as a biomarker / Roberta B. Sciurano and Alberto J. Solari
Atomic force microscopy for analyzing metaphase chromosomes : comparison of AFM images with fluorescence labeling images of banding patterns / Osamu Hoshi and Tatsuo Ushiki
Selective detection of phagocytic phase of apoptosis in fixed tissue sections / Vladimir V. Didenko
Selective transport of cationized fluorescent topoisomerase into nuclei of live cells for DNA damage studies / Candace L. Minchew and Vladimir V. Didenko
Visualization and interpretation of eukaryotic DNA replication intermediates in vivo by electron microscopy / Kai J. Neelsen, Arnab Ray Chaudhuri, Cindy Follonier, Raquel Herrador, and Massimo Lopes
Combined bidimensional electrophoresis and electron microscopy to study specific plasmid DNA replication intermediates in human cells / Cindy Follonier and Massimo Lopes
Standard DNA methylation analysis in mouse epidermis : bisulfite sequencing, methylation-specific PCR, and 5-methyl-cytosine (5mC) immunological detection / Jesús Espada, Elisa Carrasco, and María I. Calvo
Methyl-combing : single-molecule analysis of DNA methylation on stretched DNA fibers / Attila Németh
Investigating 5-hydroxymethylcytosine (5hmC) : the state of the art / Colm E. Nestor, James P. Reddington, Mikael Benson, and Richard R. Meehan
Hydroxymethylated DNA immunoprecipitation (hmeDIP) / Colm E. Nestor and Richard R. Meehan
Microscale thermophoresis for the assessment of nuclear protein-binding affinities / Wei Zhang, Stefan Duhr, Philipp Baaske, and Ernest Laue
Analysis of histone posttranslational modifications from nucleolus-associated chromatin by mass spectrometry / Stefan Dillinger, Ana Villar Garea, Rainer Deutzmann, and Attila Németh
Salt-urea, sulfopropyl-sepharose, and covalent chromatography methods for histone isolation and fractionation / Pedro Rodriguez-Collazo
Chromatin immunoprecipitation / Javier Rodríguez-Ubreva and Esteban Ballestar
Analysis of chromatin composition of repetitive sequences : the ChIP-Chop assay / Raffaella Santoro
Purification of specific chromatin domains from single- copy gene loci in Saccharomyces cerevisiae / Stephan Hamperl, Christopher R. Brown, Jorge Perez-Fernandez, Katharina Huber, Manuel Wittner, Virginia Babl, Ulrike Stöckl, Hinrich Boeger, Herbert Tschochner, Philipp Milkereit, and Joachim Griesenbeck
Deep sequencing of small chromatin-associated RNA : isolation and library preparation / Sarah Daniela Diermeier, Thomas Schubert, and Gernot Längst
Deep sequencing of small chromatin-associated RNA : bioinformatic analysis / Sarah Daniela Diermeier and Gernot Längst. - Digitalvolume editors, Eamonn M.M. Quigley, Michio Hongo, Shin Fukudo.Summary: "The clinical problems and dilemmas which the busy clinician encounters on a daily basis are the main focus of this publication. Emphasizing a clinical rather than a pathophysiological approach to problems, it facilitates access and helps the practicing clinician to develop an effective and efficient diagnostic and therapeutic strategy. Nevertheless, clinically important aspects of pathophysiology are also dealt with in detail when called for. A variety of scenarios that are especially relevant to modern medical practice, such as the intensive care unit, are taken into account. A group of internationally renowned experts guides the reader through the broad variety of diagnostic options available to assist in the assessment of symptoms originating anywhere along the gastrointestinal tract, from the esophagus to the anus, and, in each instance, every effort is made to critically appraise the technology discussed. Moreover, general overviews of broadly relevant therapeutic approaches are also provided. Pediatric and adult gastroenterologists, gastrointestinal surgeons and hospitalists will find this publication to be a valuable help in their daily practice"--Publisher's description.
Contents:
Oropharyngeal dysphagia and swallowing dysfunction / Sifrim, D.; Vilardell, N.; Clavé, P.
Nonobstructive dysphagia / Hongo, M.; Shoji, T.; Endo, Y.
Gastroparesis / Parkman, H.P.
The role of gastric sensorineural dysfunction in functional dyspepsia / Tack, J.
Chronic intestinal pseudo-obstruction : a neuropathological approach / De Giorgio, R.; Boschetti, E.; Bianco, F.; Cogliandro, R.F.; Volta, U.; Caio, G.; Corinaldesi, R.; Stanghellini, V.
Small intestinal dysmotility, its role in irritable bowel syndrome and small intestinal bacterial overgrowth : assessment and management / Quigley, E.M.M.
When and how should we study colonic motility? / Fukudo, S.; Machida, T.; Endo, Y.; Shoji, T.; Kano, M.; Kanazawa, M.
Difficult defecation : what really helps to assess dysfunction and guide therapy / Corazziari, E.S.
Functional gastrointestinal disorders : the mind-body dimension / Van Oudenhove, L.
The role of psychosocial factors in functional gastrointestinal disorders / Lackner, J.M.
The pharmacology of the gut-brain axis : prospects for future therapeutic progress? / Gabbard, S.; Lacy, B.E.
Specific clinical contexts. Pt. 1: the intensive care unit / Quigley, E.M.M.
Specific clinical contexts. Pt. 2: the patient with neurological disease / Choi, M.-G.
Specific clinical contexts. Pt. 3: the child with neurodevelopmental delay / Carvalho, R.; Di Lorenzo, C.
Specific clinical contexts. Pt. 4: the postoperative patient / Bassotti, G.; Villanacci, V.; Battaglia, E.; Maurer, C.A.Digital Access Karger 2014 - DigitalBrian E. Lacy, Michael D. Crowell, John K. DiBaise, editors.Contents:
Globus
Dysphagia
Noncardiac Chest Pain
Functional Gastrointestinal and Motility Disorders: Gastroesophageal Reflux Disease
Aerophagia, Belching, and Rumination
Dyspepsia
Chronic nausea
Gastroparesis
Cyclical Vomiting Syndrome
Gas and Bloating
Small Intestinal Bacterial Overgrowth
Chronic Intestinal Pseudo-Obstruction
Functional Gallbladder Disorder
Right Upper Quadrant Pain after Cholecystectomy
Chronic Constipation
Irritable Bowel Syndrome
Colonic Inertia
Chronic Diarrhea
Fecal Incontinence
Rectal Pain
Complementary and Alternative Management Strategies in Irritable Bowel Syndrome
Appendix: Answers to Teaching Questions.Digital Access Springer 2015 - DigitalJavier Gavilán, Alejandro Castro, Laura Rodrigáñez, Jesús Herranz.Summary: "This updated second edition presents a unique point of view based on fascial dissection techniques developed by several generations of renowned surgeons at La Paz University Hospital, Spain. This book lays a foundation with in-depth discussion of fascial compartmentalization of the neck. The text covers the evolution of modern neck dissection, from George Crile in 1906 to current cutting-edge procedures, and details the transition from radical neck dissection to a less aggressive, equally effective approach for treating lymph node metastases in head and neck cancer. The relationship between functional and selective neck dissection is discussed from a pragmatic and nonconventional perspective, elucidating the connection from historical, anatomic, and surgical standpoints. The four authors differentiate conceptual approaches, keystones in the evolution of scientific knowledge from surgical techniques, technical variations of a standard procedure designed to most effectively resolve a problem. The primary goal of this book is providing the reader with expert guidance on a full spectrum of fundamental surgical techniques"-- Provided by publisher.
Contents:
The Historical Outlook of Neck Dissection
The Rationale and Anatomical Basis for Functional and Selective Neck Dissection
The Conceptual Approach to Functional and Selective Neck Dissection
Surgical Technique
Hints and Pitfalls
Complications of Neck Surgery
Frequently Asked Questions with Answers.Digital Access - Digitaleditors: Devarajan Thangadurai, Jeyabalan Sangeetha, Ram Prasad.Digital Access Springer 2020
- DigitalChunlin Hou, editor.Summary: One of the most common problems for spinal cord injury patients is urinary system dysfunction. The book Functional Bladder Reconstruction Following Spinal Cord Injury via Neural Approaches introduces how to solve this problem using multi-disciplinary approaches. From animal model studies to surgical techniques as well as successful case reports, six kinds of surgery are presented in separate chapters. This up-to-date monograph will be a valuable resource for surgeons, urologists and neurologists caring for spinal cord injury patients. The contributors are a group of surgeons working in the fields of orthopaedics and microsurgery.
Contents:
An overview of traumatic spinal cord injury
Clinical anatomy of cauda equina and lumbosacral nerve root
Classification of and Treatment Principles for Bladder Dysfunction Caused by Spinal Cord Injury
Pathological changes in the detrusor after spinal cord injury
Microstructural study of the detrusor muscle after repair of atonic bladders caused by injury to the medullary cone in rats
Selective sacral rhizotomy: introducing a simple intraoperative manometric method
Reconstruction of bladder innervation below the level of spinal cord injury for inducing urination by Achilles tendon -to - bladder reflex contractions
Reconstruction of bladder innervation above the level of spinal cord injury for inducing urination by abdomen-to-bladder reflex contractions
Reconstruction of afferent and efferent nerve pathways of the atonic bladder
Transfer of normal lumbosacral nerve roots to reinnervate atonic bladder
Electrical stimulated micturition: Sacral Anterior Root Stimulator+Sacral deafferentation. - DigitalJay J. Pillai, editor.Summary: This book presents a comprehensive overview of current state-of-the-art clinical physiological imaging of brain tumors.? It focuses on the clinical applications of various modalities as they relate to brain tumor imaging, including techniques such as blood oxygen level dependent functional magnetic resonance imaging, diffusion tensor imaging, magnetic source imaging/magnetoencephalography, magnetic resonance perfusion imaging, magnetic resonance spectroscopic imaging, amide proton transfer imaging, high angular resolution diffusion imaging, sodium imaging, and molecular imaging. Featuring contributions from renowned experts in functional imaging, this book examines the diagnosis and characterization of brain tumors, details the application of functional imaging to treatment planning and monitoring of therapeutic intervention, and explores future directions in physiologic brain tumor imaging. Intended for neuro-oncologists, neurosurgeons, neuroradiologists, residents, and medical students, Functional Brain Tumor Imaging is a unique resource that serves to advance patient care and research in this rapidly developing field.
Contents:
Section I: Diagnosis and Characterization of Brain Tumors
MR Perfusion Imaging: ASL, T2*-Weighted DSC, and T1-Weighted DCE Methods
Diffusion Tensor Imaging: Introduction and Applications to Brain Tumor Characterization
Diagnosis and Characterization of Brain Tumors: MR Spectroscopic Imaging
Section II: Physiologic Imaging for Planning and Monitoring of Therapeutic Intervention
BOLD fMRI for Presurgical Planning: Part I
BOLD fMRI for Presurgical Planning: Part II
DTI for Presurgical Mapping
Magnetoencephalographic Imaging for Neurosurgery
Imaging Metabolic and Molecular Functions in Brain Tumors with Positron Emission Tomography (PET)
Proton Magnetic Resonance Spectroscopy and Spectroscopic Imaging of Primary Brain Tumors
Section III: Future Directions in Physiologic Brain Tumor Imaging
Role of Amide Proton Transfer (APT)-MRI of Endogenous Proteins and Peptides in Brain Tumor Imaging
Advanced Diffusion MR Tractography for Surgical Planning
Ultra-High Field MRSI (7T and Beyond)
Sodium Magnetic Resonance Imaging in the Management of Human High-Grade Brain Tumors
Future Clinical Applications of Molecular Imaging: Nanoparticles, Cellular Probes, and Imaging of Gene Expression. - DigitalSougata Jana, Subrata Jana, editors.Summary: Thanks to their unique properties, chitosan and chitosan-based materials have numerous applications in the field of biomedicine, especially in drug delivery. This book examines biomedical applications of functional chitosan, exploring the various functions and applications in the development of chitosan-based biomaterials. It also describes the chemical structure of chitosan and discusses the relationship between their structure and functions, providing a theoretical basis for the design of biomaterials. Lastly, it reviews chemically modified and composite materials of chitin and chitosan derivatives for biomedical applications, such as tissue engineering, nanomedicine, drug delivery, and gene delivery.
Contents:
Chapter 1. Chitosan and its Derivatives: a New Versatile Bio-polymer for Various Applications
Chapter 2. Application of Chitosan in Oral Drug Delivery
Chapter 3. Transdermal Delivery of Chitosan Based Systems
Chapter 4 . Chitosan Based Ocular Drug Delivery systems
Chapter 5. Functional Chitosan Carriers for Oral Colon-Specific Drug Delivery
Chapter 6. Chitosan-based Hydrogels for Drug Delivery
Chapter 7. Recent Advances of Chitosan based Systems for Delivery of Anticancer Drugs
Chapter 8. Chitosan-based systems for Gene Delivery
Chapter 9. Chitosan-based Interpenetrating Polymer Networks: Drug Delivery Application
Chapter 10. Chitosan-based Systems in Tissue Engineering
Chapter 11. Chitosan based Nanoformulation as Carriers of Small Molecules for Tissue Regeneration
Chapter 12. Chitosan based Systems for Theranostic Applications
Chapter 13. Grafted Chitosan Systems for Biomedical Applications
Chapter 14. Chitosan-based Systems for Controlled Delivery of Antimicrobial Peptides for Biomedical Application
Chapter 15. Antibacterial Activity of Chitosan based Systems. - DigitalGirdhar K. Pandey, Sibaji K. Sanyal.Summary: This book focuses on the significance and implications of Calcium (Ca2+) transport machinery in the plant cell in generating alternating Ca2+ levels and impacting the cell's physiological, biochemical and developmental processes. In the following sections, the concept of Ca2+ homeostasis, Ca2+ signature, various Ca2+ transport protein families and conductance systems would be discussed in detail- elucidation of their functional characterization, structure, mechanism, sub-cellular localization and specific physiological roles in ensuring Ca2+ homeostasis. Also, the aspect of Ca2+ as a "signaling hub" -transducing distinct plant responses to diverse environmental stimuli, Ca2+ binding proteins, and the tools used in studying these proteins are explained in brief to paint a holistic picture of Ca2+ transport in plant systems. This has resulted in an elaborative literature account to serve as a staple by providing recent insights and advance knowledge surrounding genetic and molecular dissection of Ca2+homeostasis maintenance mechanisms and extant Ca2+ transport systems in plants.
Contents:
Calcium: from nutrition to signaling
Calcium homeostasis, reserves and transport elements in the cell
The concept of calcium signature and its involvment in other signaling pathways
Calcium binding proteins : 'decoders of Ca2+ siganture'
Plant ion channels without molecular identity and two-pore channel 1
Plant ligand-gated ion channels 1: GLR
Plant ligand-gated channels 2: CNGC
Annexin and mechanosensitive channel
Ca2+-ATPase and Ca2+/cation antiporters
Tools for analysing Ca2+ transport elements and future perspectives. - DigitalKazunari Tominaga, Hiroaki Kusunoki, editors.Summary: The research and outcomes presented in this book gather evidence concerning both the pathogenesis and treatment of functional dyspepsia. It provides the latest information on this common non-organic disease, indicating its characteristic pathogenesis based on the brain-gut interaction and micro-environment and evidence gleaned from clinical treatment. Since the pathogenesis is associated with psychology, neurology, endocrinology and bacteriology in addition to gastroenterological physiology, it is often intractable and finding a suitable treatment rationale is challenging. Furthermore, the pathogenesis varies around the world and the efficacy of treatment using standard drugs varies among different populations worldwide; accordingly, this book highlights evidence gained in clinical trials in Japan. Functional Dyspepsia is a milestone produced by respected experts. Addressing unique topics and new findings of treatment including challenging and/or future rationales, it offers an invaluable resource for general clinicians, gastroenterologists, and basic researchers alike.
Contents:
PART I: Etiology.-Chapter 1: Definition & Prevalence
Chapter 2: Genetic Factor
Chapter 3: Environmental Factors
PART II: Pathophysiology
Chapter 4: Neuro-gastroenterology: Central & Autonomic Nervous System.-Chapter 5: Neuro-gastroenterology: Enteric Nervous System
Chapter 6: Neuro-gastroenterology: Esophago-gastric Function (Motility) .-Chapter 7: Neuro-Gastroenterology: Gastro-duodenal Function (Motility) and Ultrasonographic Assessment.-Chapter 8: Ghrelin and Functional Dyspepsia
Chapter 9: Psycho-gastroenterology
Chapter 10: Visceral Hypersensitivity Through Transient Receptor Potential Vanilloid 1 Channels (TRPV1) in Functional Dyspepsia.-PART III: Treatment.-Chapter 11: Efficacy of Acid Suppression Therapy.-Chapter 12: Prokinetics.-Chapter 13: Herbal Medicine.-PART IV: Recent Special Topics: Future Treatment Possibility
Chapter 14: Gut Dysbiosis and Its Treatment in Patients with Functional Dyspepsia
Chapter 15: Visceral Hypersensitivity in Functional Dyspepsia (FD)
Therapeutic Approaches to FD Based on Suppression of Visceral Hypersensitivity
Chapter 16: Pancreatic Exocrine Function. - DigitalFunctional electrical stimulation in neurorehabilitation : synergy effects of technology and therapyThomas Schick, editor.Summary: This book explains to physical therapists, occupational therapists, speech therapists, interested physicians and clinicians the theoretical and practical applications of single- to multi-channel functional electrical stimulation for a wide range of neurological symptoms. The targeted electrical stimulation of several muscle groups, timed to each other, can initiate and support a complete movement sequence and thus improve motor learning. Renowned experts from research and practice have compiled numerous application examples based on the available evidence in this comprehensive form for the first time. In addition, the reader will find exciting and informative contributions to the current study situation and effectiveness analyses. The text is enriched by videos on EMG-triggered functional multichannel electrical stimulation, stimulation of muscle groups in lower motor neuron lesions, and FES therapy approaches for dysarthria and swallowing disorders. From the contents: - FES in lesions of the upper motoneuron, lesion of the lower motoneuron and mixed forms - Combination of FES with mirror therapy and botulinum toxin - Motor learning, neuroplasticity, ICF-based goal setting and the use in home-based therapy - Basic principles, current parameters and their implications - FES in rehabilitation of facial paralysis, unilateral vocal fold paralysis, dysarthria and dysphagia, and neuro-urological deficits .
Contents:
1 Introduction and history of Functional Electrical Stimulation (FES)
2 Plasticity and motor learning
3 Clarification models and mode of action of FES
4 Role of electrical parameters in FES
5 ICF-based goals in FES
6 FES for motor function disorders due to damage to the central nervous system
7 FES to improve mobility
8 Electrical stimulation for improvement of function and muscle architecture in lower motor neuron lesions
9 Sensory afferent stimulation
10 FES in facial rehabilitation
11 FES in dysphagia treatment
12 Treatment of dysarthria with FES
13 FES in unilateral vocal fold paralysis
14 Combination therapies with FES
15 FES in neuro-urologic disorders
16 FES and home-based therapy
17 Evidence on FES
18 Absolute and relative contraindications. . - DigitalVibha Rani, Umesh C.S. Yadav, editors.Summary: Global health and the increasing incidence of various diseases are a cause for concern, and doctors and scientists reason that the diet, food habits and lifestyle are contributing factors. Processed food has reduced the nutritional value of our diet, and although supplementing foods with various additives is considered an alternative, the long-term impact of this is not known. Many laboratories around the world are working to identify various nutritional components in our daily food and their effect on human health. These have been classified as Nutraceuticals or functional food, and they may have preventive and therapeutic effects in a number of pathologies associated with modern dietary habits and lifestyles. This book addresses various aspects of this issue, revitalizing the discussion and consolidating the latest research on nutritional and functional food and their effects in in-vitro, in-vivo and human clinical studies.
Contents:
Intro; Foreword; Preface; Contents; Contributors; About the Editors; Part I: Functional Food Components in Daily Diet;
1: Composition ofFunctional Food inWorld Diet; 1.1 Introduction; 1.2 Market ofFunctional Foods; 1.2.1 Status ofFunctional Food at International Level; 1.2.2 Status ofFunctional Foods at Indian Level; 1.2.3 Suppliers ofFunctional Food totheIndian Market; 1.3 Fast-Growing Categories of Functional Foods; 1.3.1 Probiotics asFunctional Foods; 1.3.2 Beverages asFunctional Foods; 1.3.2.1 Green Tea; 1.3.2.2 Dairy-Based Beverages; 1.3.2.3 Sports Drinks 1.3.2.4 Wine1.3.3 Dietary Fiber asFunctional Foods; 1.3.4 Fruits andVegetables asFunctional Foods; 1.4 Challenges andOpportunities ofFunctional Foods; 1.5 Conclusion; References;
2: Dietary Fibre- Nutrition andHealth Benefits; 2.1 Introduction; 2.2 Constituents ofDietary Fibre; 2.3 Soluble Dietary Fibre (SDF); 2.4 Insoluble Dietary Fibre (IDF); 2.5 Dietary Fibre Requirements; 2.6 Dietary Fibre: Nutritional andHealth Significance; 2.7 Role ofDietary Fibre inPhysiological Well-Being; 2.8 Conditions Linked toLow-Fibre Diets; 2.9 Dietary Fibre andCardiovascular Diseases 2.10 Dietary Fibre andDiabetes2.11 Dietary Fibre andColorectal Cancer; 2.12 Dietary Fibre andHealthy Ageing; 2.13 Conclusion; References;
3: Phlorotannins andMacroalgal Polyphenols: Potential AsFunctional Food Ingredients andRole inHealth Promotion; 3.1 Introduction; 3.2 Macroalgal Sources ofPolyphenols; 3.3 Classification andStructure ofPhlorotannins; 3.4 Phlorotannin Content ofMacroalgae; 3.5 Identification andAnalysis ofMacroalgal Phlorotannins; 3.6 Dietary Intake ofMacroalgal Phlorotannins; 3.6.1 Bioavailability ofPolyphenols 3.7 Role ofMacroalgal Polyphenols inHuman Health3.7.1 Anti-hyperglycaemic Effects; 3.7.1.1 In Vitro Studies; 3.7.1.2 Animal Studies; 3.7.1.3 Human Studies; 3.7.1.4 Summary; 3.7.2 Anti-hyperlipidaemic Effects; 3.7.2.1 In Vitro Studies; 3.7.2.2 Animal Studies; 3.7.2.3 Human Studies; 3.7.2.4 Summary; 3.7.3 Health Effects According toAlgal Species; 3.8 Macroalgae AsaFunctional Food Ingredient; 3.8.1 Safe Levels ofConsumption; 3.8.2 Additional Bioactive Compounds inMacroalgae; 3.8.3 Availability andSustainability ofMacroalgae AsaFunctional Food Source 3.8.4 Processing ofMacroalgae forConsumption3.8.5 Incorporation ofMacroalgae into Foods; 3.8.6 Commercial Potential ofFunctional Foods; 3.9 Conclusion; References;
4: Probiotics asFunctional Foods inEnhancing Gut Immunity; 4.1 Introduction; 4.2 Microflora ofGastrointestinal Tract andOther Organs; 4.2.1 The Gastrointestinal Tract; 4.2.1.1 Role ofGut Mucosa andGut-Associated Lymphoid Tissue inHost Immune System; 4.2.1.2 Intestinal Microflora andDevelopment oftheHost Immune System; 4.2.1.3 Colorectal Cancer; 4.2.1.4 Adhesion ofProbiotics toTarget Sites - Digitaledited by Athapol Noomhorm, Imran Ahmad, and Anil Anal.Contents:
I Fundamentals of Functional Food Processing
1. Functional Foods, Nutraceuticals and Probiotics as Functional Food Components / Athapol Noomhorm, Anil Kumar Anal, Imran Ahmad
2. Bioactive Components in Foods / Anil Kumar Anal, Kishore K. Kumaree, Mridula Thapa
II Major Sources of Functional Foods
3. Processing Effects on Functional Components in Cereals and Grains / Binod K. Yadav, J. Jerish Joyner
4. Tropical Fruits / Mandeep Kaur, H.K. Sharma
5. Bioactive Compounds in Meat and their Functions / Punchira Vongsawasdi, Athapol Noomhorm
6. Bioactive Materials Derived from Seafood and Seafood Processing By-products / Ratih Pangestuti, Se-Kwon Kim
7. Food Processing By-products as Sources of Functional Foods and Nutraceuticals / Nina Karla M. Alparce, Anil Kumar Anal
8. Functionality of Non-starch Polysaccharides (NSPs) / Kelvin K.T. Gob, Ramesh Kumar, Shen-Siung Wong
9. Resistant Starch: Properties, Preparations and Applications in Functional Foods / Taslima Ayesha Aktar Nasrin, Anil Kumar Anal
10. Isoflavones
Extraction and Bioavailability
Khoomtong Atcharaporn, Pananun Thawunporn, Buddhi Lamsal
III Processing Effects on the Functional Components during Product Development
11. Thermal and Non-thermal Processing of Functional Foods / Jiraporn Sripinyowanich Jongyingcharoen, Imran Ahmad
12. Changes of Properties and Functional Components of Extruded Foods / Vilai Rungsardthong
13. Recent Advances in Applications of Encapsulation Technology for the Bioprotection of Phytonutrients in Complex Food Systems / Alisha Tuladhar, Anil Kumar Anal
14. The Effect of Irradiation on Bioactive Compounds in Plant and Plant Products / Nantarat Na Nakornpanom, Porntip Sirisoontaralak
15. Nanoparticles and Nanoemulsions / Anges Teo, Kelvin K.T. Goh, Sung Je Lee
IV Health Benefits and Bioavailability of Functional Foods
16. Pharmacology and Health Benefits of Bioactive Food Sources / Maushmi S. Kumar, Shruti Mishra
17. Potential Cardio-protective Effects of Functional Foods / Eman M. Alissa, Gordon A. Ferns.Digital Access Wiley 2014 - Digital[edited by] Antonio Luna, Joan C. Vilanova, L. Celso Hygino da Cruz Jr., Santiago E. Rossi.Contents:
Part I. Clinical and therapeutic approach to functional oncological imaging
part II. Imaging of cancer hallmarks
part III. Functional imaging techniques in clinical use
part IV. Molecular imaging techniques in clinical use and in research.Digital Access Springer 2014 - Digitaledited by Antonio Luna, Joan C. Vilanova, L. Celso Hygino da Cruz, Jr., Santiago E. Rossi.Contents:
Tumors of the CNS and Spinal Cord
Functional Magnetic Resonance Techniques in CNS Tumors
MR Imaging Evaluation of Posttreatment Changes in Brain Neoplasms
Metastasis and Other Tumors of the CNS
Spinal Cord Tumors: Anatomic and Advanced Imaging
Head and Neck Cancer
Chest Malignancies
Lung Cancer: PET, Perfusion CT, and Functional MR Imaging
Functional Imaging of Malignant Pleural Mesothelioma and other Pleural and Chest Wall Lesions
Functional Imaging of Malignant Pleural Mesothelioma and other Pleural and Chest Wall Lesions
Thymomas and Other Thymic Primary Malignancies of the Chest
Functional Imaging in Cardiac Tumors
Women's Cancers
Breast Cancer
PET-CT of Gynecological Malignancies and Ovarian Cancer
Functional MRI of Uterine (Endometrial and Cervical) Cancer
Functional Imaging of Ovarian Cancer and Peritoneal Carcinomatosis
Malignancies of the Gastrointestinal System
Esophagus, Stomach, and Small Bowel Malignancies
Colorectal Cancer
Hepatobiliary and Pancreatic Malignancies
Overview of Functional Imaging Techniques for Liver Malignancies in Current Clinical Practice or in a Very Near Future
Hepatocellular Carcinoma
Role of Functional MRI in the Management of Liver Metastases
Other Malignant Lesions of the Liver
Functional Imaging of Gallbladder and Biliary Malignancies
Splenic Lesions
Genitourinary Tract Tumors
Functional Imaging of Renal Cell Carcinoma
Functional CT and MRI of the Urinary System and Adrenal Glands
Prostate Cancer
Scrotum
Functional Imaging of Tumors of the Mesenterium and Retroperitoneum
Malignancies of the Endocrine System
Functional Oncological Imaging of the Endocrine System
Hematological Malignancies
Functional Imaging in Clinical Use for the Assessment of Lymph Nodes in Oncological Patients
Functional Imaging in Lymphoma
Multiple Myeloma and Other Hematological Malignancies
Malignant Tumors of the Musculoskeletal System
Advanced MRI Techniques of Soft Tissue Tumors
Bone Malignancies
Bone Metastasis
Functional Imaging of Pediatric Malignancies
Malignant Melanoma.Digital Access Springer 2014 - PrintJarlstedt, Jan.Contents:
v. 2. RNA changes in rabbit cerebellar Purkinje cells after caloric stimulation and vestibular neurotomy.Access via Acta physiologica Scandinavica. 1966; 271 - PrintScott A. Huettel, Allen W. Song, Gregory McCarthy.Contents:
An introduction to fMRI
MRI scanners
Basic principles of MR signal generation
Basic principles of MR image formation
MRI contrast mechanisms and acquisition techniques
From neuronal to hemodynamic activity
Properties of the fMRI bold response
Signal, noise, and preprocessing of fMRI data
Experimental design
Statistical analysis I: basic analysis
Statistical analysis II: data-driven approaches
Advanced fMRI methods
Combining fMRI with other techniques
The future of fMRI: practical and ethical issues. - DigitalXingfeng Li.Summary: With strong numerical and computational focus, this book serves as an essential resource on the methods for functional neuroimaging analysis, diffusion weighted image analysis, and longitudinal VBM analysis. It includes four MRI image modalities analysis methods. The first covers the PWI methods, which is the basis for understanding cerebral flow in human brain. The second part, the book s core, covers MRI methods in three specific domains: first level analysis, second level analysis, and effective connectivity study. The third part covers the analysis of Diffusion weighted image, i.e. DTI, QBI and DSI image analysis. Finally, the book covers (longitudinal) VBM methods and its application to Alzheimer s disease study.
Contents:
MRI perfusion weighted imaging analysis
Perfusion imaging
Gamma-variate fitting
AIF selection
Dispersion effects in DSC-MRI
-Summary of the PWI algorithm
First level fMRI data analysis for activation detection
fMRI experimental design
fMRI data pre-processing
Activation detection: model free and model based methods
Models for hemodynamic response function and drift
General linear model (GLM) for activation detect
Hypothesis test and threshold correction
Summary of algorithm for 1st level fMRI data analysis
2nd level fMRI data analysis using mixed model
Mixed model for fMRI data analysis
Numerical analysis for mixed effect models
Iterative trust region method for ML estimation
Exception trust region algorithm for second level fMRI data analysis
Degree of freedom (DF) estimation
fMRI data analysis future directions
Second level fMRI data processing algorithm summary.- fMRI effective connectivity study
Nonlinear system identification method for fMRI effective connectivity analysis
Model selections for effective connectivity study
Robust method for second level analysis
Effective connectivity for resting-state fMRI data
Limitations for fMRI effective connectivity in this study
Summary of the algorithm for fMRI effective connectivity study.Diffusion weighted imaging analysis
Basic principle of diffusion MRI and DTI data analysis
Fiber tracking
High angular resolution diffusion imaging (HARDI) analysis
Adaptive Q-ball imaging regularization
Diffusion spectrum imaging
Summary and future directions
Summary of DTI, QBI and DSI image analysis methods
Voxel based morphometry and its application to Alzheimer s disease study
Background for voxel based morphometry analysis
Enhanced VBM
Longitudinal VBM and its application to AD study
Effective connectivity for longitudinal data analysis
Other type of sMRI data analysis
Summary of (longitudinal) VBM analysis methods.Digital Access Springer 2014 - DigitalRichard W. Byrne, editor.Contents:
Historical Perspective on the Development of Cerebral Localization, Cerebral Cortical Motor Stimulation, and Sensory Evoked Potentials
Anatomy of Important Functioning Cortex
Mapping Eloquent Brain with functional MRI and DTI
Intra-Operative Cortical Stimulation Mapping. Technique and Limitations
Anesthetic Considerations in Cortical Mapping and Awake Surgery
Mapping Cortical Function with Event-Related Electrocorticography
Mapping of Eloquent Cortex in Focal Epilepsy with Intracranial Electrodes
Somatosensory and Motor Evoked Potentials in Surgery of Eloquent Cortex Under General Anesthesia: Advantages and Limitations
Cortical Mapping with Transcranial Magnetic Stimulation
Practical application of Pre-Operative and Intra-Operative Cortical Mapping in Surgery
Epilepsy Surgery in Eloquent Cortex
White Matter Tracts
Intraoperative Cortical Stimulation and the Value of Negative Mapping. - DigitalKok Meng John Chan, editor.Summary: This book covers in detail all aspects of functional mitral and tricuspid regurgitation, from its pathophysiology and natural history, to its assessment, medical and surgical treatment, and long term results. Functional Mitral and Tricuspid Regurgitation encompasses information and knowledge from a diverse background including cardiology, cardiac surgery and basic science. This is necessary for a full understanding of the subject in order to optimally manage patients with this condition.Digital Access Springer 2017
- DigitalKathrin LaFaver, Carine W. Maurer, Timothy R. Nicholson, David L. Perez, editors.Summary: This book is a practical manual for clinical practitioners seeking to take an interdisciplinary and multidisciplinary approach to the diagnosis and management of functional movement disorder (FMD). It discusses case vignettes, reviews the diagnostic approach, provides an update on available treatments, highlights clinical pearls and details references for further reading. Organized into three parts, the book begins with a framework for conceptualizing FMD - including its historical context, the biopsychosocial model and an integrated neurologic-psychiatric perspective towards overcoming mind-body dualism. Part II then provides a comprehensive overview of different FMD presentations including tremor, dystonia, gait disorders, and limb weakness, as well as common non-motor issues such as pain and cognitive symptoms. The book concludes with chapters on updated practices in delivering the diagnosis, working with patients and care partners to achieve shared understanding of a complex condition, as well as an overview of evidence-based and evolving treatments. Supplemented with high-quality patient videos, Functional Movement Disorder is written for practicing neurologists, psychiatrists, psychologists, allied mental health professionals, and rehabilitation experts with an interest in learning more about diagnosis and management of FMD.
Contents:
Part I: Framework
1. A historical perspective on functional neurological disorder
2. Free will, emotions and agency: Pathophysiology of functional movement disorder
3. The biopsychosocial formulation for functional movement disorder
4. Integrating neurologic and psychiatric perspectives in functional movement disorder
Part II: Presentations
5. Functional limb weakness and paralysis
6. Functional tremor
7. Functional dystonia
8. Functional parkinsonism
9. Functional jerky movements
10. Functional facial disorders
11. Functional gait disorders
12. Functional tics
13. Functional speech and voice disorders
14. Beyond functional movements: The spectrum of functional neurological and somatic symptoms
15. Functional movement disorder in children
16. Functional movement disorder in older adults
Part III: Management
17. "Breaking the news" of a functional movement disorder
18. Motivational interviewing for functional movement disorder
19. Communication challenges in functional movement disorder
20. Developing a treatment plan for functional movement disorder
21. Psychological treatment of functional movement disorder
22. Psychiatric comorbidities and the role of psychiatry in functional movement disorder
23. Physical therapy: retraining movement
24. Occupational therapy: focus on function
25. Speech therapy: being understood clearly
26. Interdisciplinary rehabilitation approaches in functional movement disorder
27. Placebo effects and functional neurological disorder: helpful or harmful?
28. Transcranial magnetic stimulation (TMS) as treatment for functional movement disorder
29. Measuring symptoms and monitoring progress in functional movement disorder
30. Overcoming treatment obstacles in functional movement disorder
31. Management considerations for pediatric functional movement disorder. - Digitaledited by Stephen B. Dunnett and Anders Björklund.Contents:
Part A: Mechanisms and use of neural transplants for brain repair / Stephen B. Dunnett and Anders Björklund
Reprogramming of somatic cells: iPS and iN cells / Vania Broccoli
Brain repair from intrinsic cell sources: turning reactive glia into neurons / Olof Torper and Magdalena Götz
Ex vivo gene therapy for the treatment of neurological disorders / Genevieve Gowing , Soshana Svendsen and Clive N. Svendsen
Preparation, characterization and banking of clinical-grade cells for neural transplantation: scale up, fingerprinting and genomic stability of stem cell lines / Ammar Natalwala and Tilo Kunath
Regulatory considerations for pluripotent stem cell therapies / Melissa K. Carpenter
Strategies for bringing stem cell-derived dopamine neurons to the clinic: a European approach (STEM-PD) / Agnete Kirkeby, Malin Parmar and Roger A. Barker
Strategies for bringing stem cell-derived dopamine neurons to the clinic: the NYSTEM trial / Lorenz Studer
Strategies for bringing stem cell-derived dopamine neurons to the clinic: the Kyoto trial / Jun Takahashi
From open to large-scale randomised cell transplantation trials in Huntington's disease: lessons from the multicentric intracerebral grafting in Huntington's Disease trial (MIG-HD) and previous pilot studies / Anne-Catherine Bachoud-Lévi
Pluripotent stem cell-derived neurons for transplantation in Huntington's disease / Meng Li and Anne E. Rosser
Advanced imaging of transplant survival, fate, differentiation, and integration / Nadja Van Camp, Elsa Diguet and Philippe Hantraye
Rehabilitation training in neural restitution / Susanne Clinch, Monica Busse, Mate D. Döbrössy and Stephen B. Dunnett. Part B: Stem cell transplantation for spinal cord injury repair / Paul Lu
Plasticity and regeneration in the injured spinal cord after cell transplantation therapy / Satoshi Nori, Masaya Nakamura and Hideyuki Okano
Transplantation of GABAergic interneurons for cell-based therapy / Julien Spatazza, Walter R. Mancia Leon and Arturo Alvarez-Buylla
Rebuilding CNS inhibitory circuits to control chronic neuropathic pain and itch / Joao M. Braz, Alex Etlin, Dina Juarez-Salinas, Ida J. Llewellyn-Smith and Allan I. Basbaum
From transplanting Schwann cells in experimental rat spinal cord injury to their transplantation into human injured spinal cord in clinical trials / Mary B. Bunge, Paula V. Monje, Aisha Khan and Patrick M. Wood
Recruitment of endogenous CNS stem cells for regeneration in demyelinating disease / Natalia A. Murphy and Robin J.M. Franklin
Progenitor Cell-Based Treatment of Glial Disease / Steven A. Goldman
Pluripotent stem cells and their utility in treating photoreceptor degenerations / Nozie D. Aghaizu, Kamil Kruczek, Anai Gonzalez-Cordero, Robin R. Ali and Rachael A. Pearson
Stem cell-derived retinal pigment epithelium transplantation for treatment of retinal disease / Britta Nommiste, Kate Fynes, Victoria E. Tovell, Conor Ramsden, Lyndon da Cruz and Peter Coffey
Transplantation of reprogrammed neurons for improved recovery after stroke / Zaal Kokaia, Daniel Tornero and Olle Lindvall.Digital Access - DigitalAndreas Otte.Summary: This book offers a critical approach to the challenging interpretation of new research data obtained using functional neuroimaging in whiplash injury. It covers all aspects, including the imaging tools themselves and the different methods of image analysis.
Contents:
Intro; Preface; Acknowledgments; Contents; Abbreviations;
1: Introduction; 1.1 General Aspects; 1.1.1 The Term "Whiplash Injury"; 1.1.2 Symptoms; 1.2 Incidence; 1.3 Historical Aspects; 1.3.1 Barré's "Syndrome Sympathique Cervical Postérieur"; 1.3.2 The Term "Railway Spine"; 1.3.3 Maurice Ravel; 1.4 Biomechanics; 1.4.1 General Aspects; 1.4.2 Protection Systems to Avoid Whiplash Injury; 1.4.3 Sequence of Phases During a Typical Whiplash Injury; 1.4.4 Timing of Neck Muscle Contraction;
2: Diagnostics; 2.1 Diagnostic Procedure After Whiplash Injury; 2.2 New Iteration Algorithms 2.3 Stereotaxic Atlas of Talairach and Tournoux2.4 Other Stereotaxic Atlas Systems; 2.4.1 Computerized Brain Atlas; 2.4.2 Montreal Atlas; 2.5 Statistical Parametric Mapping (SPM); 2.6 Control Group;
3: Current Research Data; 3.1 Mild Traumatic Brain Injury; 3.1.1 General Aspects; 3.1.2 Special Cases; 3.1.2.1 Bicycle Accident; 3.1.2.2 Car Accident; 3.2 Whiplash Injury; 3.2.1 Early Studies from Otte et al.; 3.2.2 Studies from Bicik/Radanov et al.; 3.2.3 Newer Studies from 2002 to 2012; 3.2.4 Latest Studies: Whiplash Revisited 3.3 3D Visualization of Regions of Cerebral Activation and Deactivation3.4 Excursus on Functional Brain Regions; 3.5 Differential Diagnostic List; 3.6 Whiplash Trauma and the Risk of Alzheimer's Disease;
4: Conclusion; 4.1 The Dilemma; 4.2 Future Research;
5: Clinical Aspects; About the Author; BibliographyDigital Access Springer 2019 - DigitalAndreas Otte.Summary: This book, now in its third, completely revised and updated edition, offers a critical approach to the challenging interpretation of the latest research data obtained using functional neuroimaging in whiplash injury. Such a comprehensive guide to recent and current international research in the field is more necessary than ever, given that the confusion regarding the condition and the medicolegal discussions surrounding it have increased further despite the publication of much literature on the subject. In recent decades especially the functional imaging methods such as single-photon emission tomography, positron emission tomography, functional MRI, and hybrid techniques have demonstrated a variety of significant brain alterations. Functional Neuroimaging in Whiplash Injury - New Approaches covers all aspects, including the imaging tools themselves and the various methods of image analysis. Details on biomechanics, including the finite element method and facts on historical whiplash experiments and crash tests have now been added to this new edition. The book will continue to help physicians, patients and their relatives and friends, and others to understand this condition as a disease.
Contents:
Introduction
Diagnostics
Current Research Data
Conclusion
Clinical Aspects. - Digitaledited by Mark Hallett, Jon Stone and Alan Carson.Contents:
A brief history of hysteria: From the ancient to the modern / M. Trimble, E.H. Reynolds
Charcot, hysteria, and simulated disorders / C.G. Goetz
Neurologic approaches to hysteria, psychogenic and functional disorders from the late 19th century onwards / J. Stone
Freud's hysteria and its legacy / R.A.A. Kanaan
Epidemiology / A. Carson, A. Lehn
Neurophysiologic studies of functional neurologic disorders / M. Hallett
Imaging studies of functional neurologic disorders / S. Aybek, P. Vuilleumier
Dissociation and functional neurologic disorders / R.J. Brown
Hypnosis as a model of functional neurologic disorders / Q. Deeley
Psychologic theories in functional neurologic disorders / A. Carson, L. Ludwig, K. Welch
Voluntary or involuntary? A neurophysiologic approach to functional movement disorders / M.-P. Stenner, P. Haggard
Neurobiologic theories of functional neurologic disorders / M.J. Edwards
Stress, childhood trauma, and cognitive functions in functional neurologic disorders / K. Roelofs, J. pasman
Do (epi)genetics impact the brain in functional neurologic disorders? / T. Frodl
Assessment of patients with functional neurologic disorders / A. Carson, M. Hallett, J. Stone
The classification of conversion disorder (functional neurologic symptom disorder) in ICD and DSM / J.L. Levenson, M. Sharpe
Neurologic diagnostic criteria for functional neurologic disorders / C. Gasca-salas, A.E. Lang
Functional limb weakness and paralysis / J. Stone, S. Aybek
Functional tremor / P. Schwingenschuh, G. Deuschl
Functional dystonia / D.A. Schmerler, A.J. Espay
Functional jerks, tics, and paroxysmal movement disorders / Y.E.M. Dreissen, D.C. Cath, M.A.J. Tijssen
Psychogenic (functional) parkinsonism / M.A. Thenganatt, J. Jankovic
Functional gait disorder / V.S.C. Fung
Functional sensory symptoms / J. Stone, M. Vermeulen
Nonepileptic seizures & subjective phenomena / M. Reuber, G.H. Rawlings
Nonepileptic seizures & objective phenomena / W.Curt Lafrance Jr., R. Ranieri, A.S. Blum
Psychogenic nonepileptic seizures: EEG and investigation / R. Duncan
Functional coma / L. Ludwig, L. McWhirter, S. Williams, C. Derry, J. Stone
Functional and simulated visual loss / M. Dattilo, V. Biousse, B.B. Bruce, N.J. Newman
Functional eye movement disorders / D. Kaski, A.M. Bronstein
Functional facial and tongue movement disorders / A. Fasano, M. Tinazzi
Functional auditory disorders / D.M. Baguley, T.E. Cope, D.J. McFerran
Functional speech disorders: clinical manifestations, diagnosis, and management / J.R. Duffy
Functional voice disorders: Clinical presentations and differential diagnosis / J. Baker
Psychologic/functional forms of memory disorder / J. Griem, J. Stone, A. Carson, M.D. Kopelman
Functional (dissociative) retrograde amnesia / H.J. Markowitsch, A. Staniloiu
Functional (psychogenic) dizziness / M. Dieterich, J.P. Staab, T. Brandt
Urologic symptoms and functional neurologic disorders / I. Hoeritzauer, V. Phé, J.N. Panicker
Functional disorders of swallowing / A. Baumann, P.O. Katz
Pediatric functional neurologic symptoms / P.J. Grattan-Smith, R.C. Dale
Posttraumatic functional movement disorders / C. Ganos, M.J. Edwards, K.P. Bhatia
Factitious disorders and malingering in relation to functional neurologic disorders / C. Bass, P. Halligan
Prognosis of functional neurologic disorders / J. Gelauff, J. Stone
Explanation as treatment for functional neurologic disorders / J. Stone, A. Carson, M. Hallett
Physical treatment of functional neurologic disorders / G. Nielsen
Psychologic treatment of functional neurologic disorders / L.H. Goldstein, J.D.C. Mellers
Hypnosis as therapy for functional neurologic disorders / Q. Deeley
Nature of the placebo and nocebo effect in relation to functional neurologic disorders / E. Carlino, A. Piedimonte, F. Benedetti
The role of placebo in the diagnosis and treatment of functional neurologic disorders / K.S. Rommelfanger
Transcranial magnetic stimulation and sedation as treatment for functional neurologic disorders / T.R.J. Nicholson, V. Voon
Inpatient treatment for functional neurologic disorders / D.T. Williams, K. Lafaver, A. Carson, S. FahnDigital Access ScienceDirect 2016 - DigitalYunbo Luo.Summary: This book highlights the development of a functional nucleic acid based biosensor detection method in the context of food safety. Although there have been major advances in food processing technology in both developed and developing countries, food safety assurance systems are generally becoming more stringent, in response to growing (both real and perceived) food safety problems. These problems are due in part to foodborne microorganisms, heavy metals, and small chemical molecules (biological toxins, pesticide residues, and veterinary drug residues), etc. In addition, the nucleic acid biomarkers (DNA methylation, microRNA, and circRNA) induced by these risk factors are also closely related to food safety. Accordingly, this book offers a brief guide to targets and strategies in functional nucleic acid based biosensors for food safety detection. Divided into several chapters that focus on various respective targets, it will be a valuable resource for students and researchers in the fields of biosensor detection, food science etc.
Contents:
Intro; Preface; Contents;
Chapter 1: Functional Nucleic Acid Based Biosensors forFood Safety Detection; 1.1 Food Safety Burden: Safer Food Saves Lives; 1.2 Food Safety Risk Factors: Significant Proportion Can BePrevented; 1.2.1 Microorganisms; 1.2.2 Genetically Modified Organism (GMO); 1.2.3 Heavy Metal Ion; 1.2.4 Chemical Small Molecules; 1.2.5 Nucleic Acid Biomarkers; 1.3 Biosensor: ATrend Toward Rapid andOn-Site Detection; 1.3.1 Optical Biosensor; 1.3.2 Electrochemical Biosensor; 1.3.3 Gravimetric Biosensor; 1.4 Functional Nucleic Acid: Powerful Tools toImprove Performance. 1.4.1 Nucleic Acid asTarget Recognition ElementDNA-Based Biosensors; Aptamer-Based Biosensors; DNAzyme-Based Biosensors; Artificial Nucleic Acid-Based Biosensors; 1.4.2 Nucleic Acid asSignal Amplification; DNA Amplification Techniques; G-Quadruplex Amplification Techniques; 1.4.3 Nucleic Acid as3D Nanostructure; References;
Chapter 2: Functional Nucleic Acid Based Biosensor forMicroorganism Detection; 2.1 Introduction; 2.2 The Construction ofFunctional Nucleic Acid Based Biosensors forMicroorganism Detection andIts Technological Element. 2.2.1 Signal Recognization andTransduction ofFunctional Nucleic Acid Based Biosensor2.2.2 Signal Transduction Elements; 2.2.3 Signal Amplification ofFunctional Nucleic Acid Based Biosensor; 2.2.4 Signal Output Systems ofFunctional Nucleic Acid Based Biosensor; 2.3 Functional Nucleic Acid Based Biosensors forMicroorganism Detection; 2.3.1 Aptamer Based Biosensors forMicroorganism Detection; 2.3.2 Functional Nucleic Acid Based Colorimetric Biosensors forMicroorganism Detection; 2.3.3 Lateral Flow Nucleic Acid Based Biosensors (LFNABs) forMicroorganism Detection. 2.3.10 Gold Nanoparticle (AuNP)-Functional Nucleic Acid Based Biosensors forMicroorganism Detection2.3.11 Silver Nanoparticle (AgNP)-Functional Nucleic Acid Based Biosensors forMicroorganism Detection; 2.3.12 Nanozyme-Functional Nucleic Acid Based Biosensors forMicroorganism Detection; 2.3.13 Magnetic Nanoparticle (MNP)-Functional Nucleic Acid Based Biosensors forMicroorganism Detection; 2.3.14 Functional Nucleic Acid Based Fluorescence Biosensors forMicroorganism Detection; 2.3.15 Functional Nucleic Acid Based Electrochemical Biosensors forMicroorganism Detection. 2.3.4 PCR-Functional Nucleic Acid Based Biosensors forMicroorganisms Quantitative Detection2.3.5 Isothermal Amplification-Functional Nucleic Acid Based Biosensors forMicroorganism Detection; 2.3.6 Functional Nucleic Acid Based High-Throughput Biosensors forMicroorganism Detection; 2.3.7 Functional Nucleic Acid Based Biosensor forLiving or Dead Bacteria Detection; 2.3.8 Artificial Nucleic Acid Based Biosensors forMicroorganism Detection; 2.3.9 DNAzyme Based Biosensors forMicroorganism Detection. - DigitalRobert Enzenauer, William Morris, Thomas O'Donnell, Jill Montrey.Summary: This practical manual reviews historical concepts, contemporary research, and diagnostic techniques for functional visual disorders. Functional Ophthalmic Disorders: Ocular Malingering and Visual Hysteria is a how-to manual that is written for the practicing ophthalmologist and optometrist, complete with color photos that allow the reader to see pictures of select conditions and diagnostic testing. In addition to the photos, videos are provided online to illustrate simulated testing and results on a mock patient to assist in the differential diagnosis. Written and edited by leaders in the field, the topics include the history and characteristics of functional disorders, the differential diagnosis of ocular malingering and hysteria, and practical testing in an ophthalmologic examination to distinguish the conditions from organic disease.
Contents:
1. Introduction And Terminology
2. History Of Functional Disorders
3. Hysterical Ocular Functional Disorders
4. Ocular Malingering
5. Differentiating Ocular Functional Disorders: Hysteria Versus Malingering
6. Overview Of The Clinician ? Patient Interaction
7. Techniques And Tests For Functional Ophthalmic Disorders
8. Testing For Functional Total Blindness
9. Tests For Simulation Of Monocular Blindness
10. Tests For Decreased Vision
11. Tests For Miscellaneous Functional Visual Complaints
12. Tests Of Historical Interest In Functional Visual Loss. - DigitalEgbert H. Huizing, John A.M. de Groot.Contents:
Basics
Pathology and diagnosis
Surgery general
Incisions and approaches
Septal surgery
Pyramid surgery
Lobular surgery
Surgery of the nasal cavity
Special subjects.Digital Access - DigitalNergis Tomen, J. Michael Herrmann, Udo Ernst, editors.Summary: This book offers a timely overview of theories and methods developed by an authoritative group of researchers to understand the link between criticality and brain functioning. Cortical information processing in particular and brain function in general rely heavily on the collective dynamics of neurons and networks distributed over many brain areas. A key concept for characterizing and understanding brain dynamics is the idea that networks operate near a critical state, which offers several potential benefits for computation and information processing. However, there is still a large gap between research on criticality and understanding brain function. For example, cortical networks are not homogeneous but highly structured, they are not in a state of spontaneous activation but strongly driven by changing external stimuli, and they process information with respect to behavioral goals. So far the questions relating to how critical dynamics may support computation in this complex setting, and whether they can outperform other information processing schemes remain open. Based on the workshop "Dynamical Network States, Criticality and Cortical Function", held in March 2017 at the Hanse Institute for Advanced Studies (HWK) in Delmenhorst, Germany, the book provides readers with extensive information on these topics, as well as tools and ideas to answer the above-mentioned questions. It is meant for physicists, computational and systems neuroscientists, and biologists.
Contents:
Intro; Foreword; Contents; Introduction; Background; Facets of Criticality; Criticality and the Brain; List of Reviewers in Alphabetical Order; Avalanche Dynamics and Correlations in Neural Systems; 1 Introduction; 2 Avalanche Activity and Power Spectra; 2.1 Neuronal Model and Avalanche Activity; 2.2 Power Spectra; 3 Inter-event Time Distributions; 3.1 Up-States and Down-States; 3.2 Avalanches and Oscillations; 4 Detrended Fluctuation Analysis; 5 Conditional Probability Analysis; 6 Conclusions; References 2.2 Plasticity Mechanisms2.3 External Input; 2.4 Readout Layer and Performance Evaluation; 2.5 Fading Memory Time Scale Estimation; 2.6 SORN Variants; 3 Spontaneous Activity: Self-Organization Towards Avalanche Criticality; 4 External Input: Readaptation and Learning; 5 A Link Between Neuronal Avalanches and Fading Memory; 6 Discussion; References; Homeostatic Structural Plasticity Can Build Critical Networks; 1 Introduction; 2 The Neuritic Field Model; 2.1 Model at a Glance; 2.2 Neuronal Activity; 2.3 Outgrowth and Connectivity; 2.4 Network Assembly, Overshoot and Homeostasis 2.5 Analytical Relationship Between Activity and Connectivity 3 In Vitro Cortical Cultures Show Different Dynamical States During Development4 Not All Mature Cortical Cultures Display Self-organized Criticality; 5 Complex Network Topologies Promote Self-organized Criticality in Cortical Assemblies; 5.1 Scale-Free Networks with Small-Worldness Features Promote Self-organized Criticality; 6 Conclusions; References; From Neurons to Networks: Critical Slowing Down Governs Information Processing Across Vigilance States; 1 Introduction; 2 The Theory of Critical Slowing Down; 3 Critical Slowing Down in Individual Neurons 4 Critical Slowing Down in Cortical Networks Is Maintained by Sleep5 Summary and Outlook; References; The Challenge of Taming a Latching Network Near Criticality; 1 Introduction; 2 The Model; 2.1 Interactions; 2.2 Dynamics; 2.3 Memories; 3 Imparting Latching Instructions with an Associative Learning Rule; 4 The Effect of Hetero-Associative Instructions on Latching Dynamics; 5 Instructed Versus Spontaneous Latching Transitions; 6 Conclusion; References; Fading Memory, Plasticity, and Criticality in Recurrent Networks; 1 Introduction; 2 Self-Organizing Recurrent Networks; 2.1 Model Dynamics Playing at the Edge of Criticality: Expanded Whole-Brain Repertoire of Connectome-Harmonics1 Introduction; 2 Oscillations, Synchrony and Harmonics in Brain Activity; 3 Synchrony in Biological Oscillators; 4 Whole-Brain Criticality and the Repertoire of Connectome Harmonics; 5 Discussion; References; Complexity of Network Connectivity Promotes Self-organized Criticality in Cortical Ensembles; 1 Introduction; 2 Micro-electrode Array (MEA) Technology for Recording Electrophysiological Activity from Large-Scale Neuronal Ensembles - DigitalRan D. Anbar, editor.Summary: Many children with medical conditions fail to improve despite physicians' best efforts. Sometimes, we ascribe this failure to lack of adherence to therapy, or to the severity of the condition. What we often fail to appreciate, however, is that sometimes the lack of improvement can be explained by the patients' psychological states. The first section of Functional Symptoms in Pediatric Disease: A Clinical Guide teaches children's health care providers to recognize functional symptoms that can complicate organic disease, as well as symptoms that are believed to be purely functional in origin. Literature reviews, case studies and quizzes are provided in each chapter, with video demonstrations included in some of the chapters. The second section of the book will help clinicians differentiate the patients for whom referral to a mental health provider is mandatory from those for whom other approaches may be useful. For the latter group, the book teaches clinicians to empower themselves by learning how to incorporate various therapies for functional disorders into their practice, including biofeedback, basic cognitive behavioral therapy techniques, hypnosis, acupressure, yoga and meditation. Practical strategies for obtaining training in these modalities are provided in the appendix. Useful for practicing clinicians including pediatricians, family practitioners, pediatric subspecialists, child psychiatrists, psychologists, other mental health care providers and practitioners of alternative and complementary medicine, Functional Symptoms in Pediatric Disease: A Clinical Guide is an important new book that will help children's health care providers consider the possible impact of functional contributions to the clinical presentation of their patients.
Contents:
Functional Symptoms In Young People: Conceptualizations, Definitions, Approaches
Functional Neurological Disorders: It Is All In The Head
Chest Pain, Syncope and Palpitations in the Pediatric Patient
Functional Symptoms in Pulmonology: Taking your Breath Away
Functional Symptoms in Gastroenterology: A Punch to the Gut
Functional Symptoms in Nephrology: Keeping It In and Letting It Out
Functional Symptoms In Pediatric Dermatology: The Canary In The Coal Mine
Psychogenic Influences Associated with Allergic Disorders
Functional and Psychosocial Ramifications of Type 1 Diabetes Mellitus in Pediatric Endocrinology
Functional Somatic Symptoms in Pediatric Hematology and Oncology
Chronic Pediatric Rheumatologic Pain Syndromes
Functional Symptoms in Infectious Disease: Reading into Titers
Functional Symptoms in Medical Genetics
Functional Symptoms in Children Who Have Developmental or Behavioral Differences
Functional Symptoms in Pediatric Emergency Medicine
Functional Symptoms in Intensive Care: The Vicious Circle of Anxiety and Symptoms
Development Of Functional Symptoms In Children Exposed To Traumatic Events
When and how to refer a patient to a mental health care provider
Cognitive-Behavioral Therapy for Youth with Functional Somatic and Internalizing Symptoms
The Use of Biofeedback and Neurofeedback in Pediatric Care
Hypnosis for Treatment of Functional Symptoms in Children
Guided Imagery for Functional Disorders
Acupuncture for the Treatment of Functional Disorders in Children
Mindfulness Meditation for Children
Adapting Yoga for Children and Adolescents with Functional Disorders
Pharmacotherapy of Functional Disorders in Children
Music Therapy in Pediatrics: Clinical Indications for the Treatment of Functional Symptoms
Play-Family Therapy: A Biobehavioral Team Approach to Chronic Medical Symptoms. - DigitalAntonio Carbone, Giovanni Palleschi, Antonio Luigi Pastore, Aurel Messas, editors.Contents:
Functional Anatomy of the Pelvic Organs
Preoperative Assessment and Intraoperative Anesthesiologic Care in Miniinvasive Laparoscopic Surgery
Preserving Continence During Laparoscopic (LRP) or Robot Assisted Radical Prostatectomy (RARP)
Selecting Patients for Continent or Incontinent, Heterotopic or Orthotopic Diversion
Robot Assisted Radical Cystectomy and Totally Intracorporeal Urinary Diversions
Treating Incontinence After Prostatectomy & Cystectomy: Role of Advanced Minimally Invasive Surgery
Preserving Sexual Function and Continence During Radical Hysterectomy
Preserving Sexual Function and Continence During Radical Rectal Surgery
Psychosexual Issues and Quality of Life After Oncologic Pelvic Surgery, with Focus on Cervical Cancer
Neurogenic Voiding Dysfunction: Physiopathology and Classification
Treatment of Pelvic Chronic Pain: Multidisciplinary Approach
Bladder Outlet Obstruction (BOO) and Neurodegenerative Disease: When is Surgery Mandatory? Botulinum Toxin Bladder Injection in the Treatment of Neurogenic Detrusor Overactivity and Idiopathic OAB
Bladder Augmentation: Is There an Indication for Mini-Invasive Surgical Approach?Digital Access Springer 2016 - Digital[edited by] Duane E. Haines, Gregory A. Mihailoff ; medical illustrator, W.K. Cunningham and M.P. Schenk ; photographer, G.W. Armstrong ; computer graphics, C.P. Runyan.Contents:
Orientation to the structure and imaging of the central nervous system
The cell biology of neurons and glia
The electrochemical basis of nerve function
Chemical signaling in the nervous system
Development of the nervous system
The ventricles, choroid plexus, and cerebrospinal fluid
The meninges
A survey of the cerebrovascular system
The spinal cord
An overview of the brainstem
The medulla oblongata
The pons and cerebellum
The midbrain
A synopsis of cranial nerves of the brainstem
The diencephalon
The telencephalon
The somatosensory system I : tactile discrimination and position sense
The somatosensory system II : nociception, thermal sense, and touch
Viscerosensory pathways
The visual system
The auditory system
The vestibular system
Olfaction and taste
Motor system I : peripheral sensory, brainstem, and spinal influence on anterior horn neurons
Motor system II : corticofugal systems and the control of movement
The basal nuclei
The cerebellum
Visual motor systems
Visceral motor pathways
The hypothalamus
The limbic system
The cerebral cortex
The neurologic examination.Digital Access ClinicalKey 2018 - Digital[edited by] Diego Marré, MD, Consultant, Department of Plastic Surgery and Reconstructive Surgery and Burns, Clinica Las Condes Emergency Public Hospital, Santiago, Chile.Contents:
Patient safety in plastic surgery
Wound healing
Wound management and pressure sores
Negative pressure wound therapy
Local anesthetics and common nerve blocks
Soft tissue infections and antibiotics in plastic surgery
Implants and biomaterials
Principles of osteosynthesis
Essentials of dermatology for plastic surgeons
Laser therapy : principles and applications in skin diseases
How to set up a research protocol in plastic surgery
Basic surgical techniques, sutures, and wound closure
Grafts : skin, fascia, nerve, tendon, cartilage, and bone
Fat grafting
Vascular anatomy of the skin and muscles
Flaps
Tissue expansion
Burns
Microsurgery
Facial trauma
Hand trauma.Digital Access - Digitaledited by Yasin Temel, Albert F.G. Leentjens, Rob M.A. de Bie, Stephan Chabardes, Alfonso Fasano.Summary: This book deals with a rapidly growing field of medical science: deep brain stimulation (DBS). Influencing deep brain networks by electrical stimulation through implanted electrodes is increasingly applied, and DBS has become a popular treatment for neurological and psychiatric indications. Professionals in the field of DBS are expected to understand classical subjects as disease mechanisms, brain anatomy and function, and clinical symptomatology of the diseases they treat. In addition, they are required to be familiar with specific patient management skills and treatment strategies. A third dimension is hardware and software-related knowledge. Depending on the degree of involvement, professionals need to understand basic or advanced concepts of stimulation protocols. All these aspects of DBS are discussed in this book. Authors from many different disciplines, from many different countries, have contributed their expertise and personal experience to this book. Their contributions reflect the multidisciplinary nature of DBS treatment. This book is written for a wide readership that involves many different professionals and disciplines, including neurologists, neurosurgeons, psychiatrists, neurophysiologists, neuroanatomists, psychologists, rehabilitation specialists, nurses, speech therapists, physiotherapists, engineers and other paramedical disciplines. In our society, where sharing expertise and experience, and global knowledge has become the new standard, patients want the best possible DBS therapy. One prerequisite for this is the presence of a well-integrated and dedicated multidisciplinary team, with up-to-date knowledge of the possibilities of DBS treatment.
Contents:
Part I General Section
1. The History of Deep Brain Stimulation
2. Anatomy of Targets for Deep Brain Stimulation
3. Mechanisms of Deep Brain Stimulation
4. Surgical and Technical Aspects of Deep Brain Stimulation
5. Future Perspectives: Adaptive Deep Brain Stimulation
6. Neurophysiology of the Basal Ganglia and Deep Brain Stimulation
7. Anaesthesia for Deep Brain Stimulation Surgery
8. Programming: General Aspects
9. Neuropsychological Assessment
10. Ethical Considerations
11. Organisation of Care for Patients Treated by Deep Brain Stimulation
Part II Neurology
12. Deep Brain Stimulation for Parkinson's Disease
13. Tremor
14. Dystonia
15. Epilepsy
16. Gilles de la Tourette syndrome
Part III Psychiatry
17. Deep Brain Stimulation in Obsessive-Compulsive Disorder
18. Deep Brain Stimulation for Depression
19. Other Indications for Deep Brain Stimulation. - DigitalAmal Chandra Kataki, Debabrata Barmon, editors.Summary: This book is a complete representation of all the gynecological cancers covering from the anatomical details of the individual gynecological organs along with the epidemiological pathophysiological aspects of the various gynecological cancers. It also covers the diagnostic workup of various gynecological cancers with recent evidence based treatment protocols. All the major gynecological oncological surgeries are described in a simple way along with photographs for easy understanding in all the chapters. In addition, numerous flowcharts and management algorithms are included in every chapters, as a ready reference for the benefits of the trainees and practitioners. This book includes chapters such as critical care in oncology, oncology nursing, benign and malignant breast disease, hormones and gynecological cancer, cancer infections and vaccines, palliative care which are not often found in many text books. Apart from these, this book has also included chapters like principles and practice of Radiation oncology, surgical oncology and medical oncology, recent advances and imaging in gynecological malignancy to make it a complete package. Thus, it will serve as an excellent reference book for surgical oncologists, general gynecologists, medical and radiation oncologists fellows and trainees.
Contents:
1 Epidemiology of Gynaecological Cancers
2 Molecular profiling of Gynaecological Cancer and Breast Cancer
3 Tumour Biomarkers in Gynaecologic Oncology
4 Cancer: Infection and Vaccines
5 Imaging of Gynaecologic Malignancy
6 Principles and practice of surgery in gynecological cancer
7 Principles of Chemotherapy Targeted Therapy and Immunotherapy in Gynaecological Malignancies
8 Principle and Practice of Radiation Oncology
9 Benign Breast Diseases
10 Breast Cancer
11 Cervical Cancer Screening
12 Management of precancerous lesions of cervix
13 Cancer of the uterine cervix
14 Endometrial Cancer
15 Uterine Sarcoma
16 Epithelial Ovarian Cancer
17 Malignant germ cell tumours of the ovary
18 Stromal tumour of ovary
19 Secondary Ovarian Tumor
20 Fallopian tube Carcinoma
21 Carcinoma Vulva
22 Carcinoma Vagina
23 Gestational Trophoblastic Disease
24 Gynaecological Cancer in Pregnancy
25 Role of MIS in Gynaecological Cancers
26 Hormone Replacement Therapy after Gynaecological Cancer
27 The Perioperative and Critical Care Aspects in Gynaecology-Oncology
28 Palliative Care in Advanced Gynecological Malignancy
29 Gynaecological Cancers and Nursing
30 Prevention and Screening in Gynecological Cancer
31 Recent Advances in Gynaecological Cancer. - DigitalChristopher Liu, Hanbin Lee, editors.Springer Nature eBook.Summary: This book provides an expert overview of all aspects of ophthalmic care in clinical practice. Areas such as external eye, cornea and conjunctiva, glaucoma, cataract, macular degeneration and diabetic retinopathy and retinal vascular events are discussed throughout the chapters. Fundamentals in Ophthalmic Practice will be a go-to guide for ophthalmologists, optometrists, orthoptists, ophthalmic nurses, ophthalmic technicians and other allied health professionals in their busy day-to-day practice.
Contents:
Ophthalmology as a career
Anatomy of the Eye, Orbit and Visual Pathway
Physiology of Vision
Ocular Symptoms
A systemic approach to diagnosis
Adnexal conditions
CONJUNCTIVA AND CORNEA
Glaucoma
Cataract
MEDICAL RETINA AND UVEITIS
Vitreous and retina
Ocular tumours
Ocular Emergencies. - Digitaleditors David E. Beck, Scott R. Steele and Steven D. Wexner.Summary: This book is a comprehensive and current guide to the diagnosis and treatment of the entire spectrum of anorectal diseases. It focuses mainly on anorectal problems, as anorectal pathology is often more complex and challenging for surgeons than colonic diseases.The book covers anorectal anatomy, physiology, and embryology as a foundation to a detailed description of preoperative, intraoperative, and post-operative patient management. All surgical procedures are shown in step-by-step detail by leading surgeons and gastroenterologists. This book will be relevant to general, colon, and rectal surgeons in training and practice, gastroenterologists, and other practitioners with an interest in anorectal diseases.Digital Access Springer 2019
- Digitaledited by Alexander Vinks, Hartmut Derendorf, Johan Mouton.Summary: Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as in drug development. Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics is designed as a reference on the application of pharmacokinetic-pharmacodynamic principles for the optimization of antimicrobial therapy, namely pharmacotherapy, and infectious diseases. The reader is introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, from basic research to clinical situations.
Contents:
Foreword
Section I: Basic Concepts and Principles
Introduction to Pharmacodynamics and micrbiology
In vitro and animal PK/PD model
MIC and breakpoints
Principles of applied PK/PD modeling
Population Pk/PD modeling and its applications to antimicrobials
Drug resistance and Drug-drug combinations
Section II: Clinical
Aminoglycosides
Beta-lactam antibiotics including continuous infusion
Macrolides
Glycopeptides
Quinolones
Other. - DigitalRani Gupta, Namita Gupta.Summary: This book provides useful information on microbial physiology and metabolism. The key aspects covered are prokaryotic diversity, growth physiology, basic metabolic pathways and their regulation, metabolic diversity with details of various unique pathways. Another focus area is stress physiology with details on varying environmental stresses, signal transduction, adaptation and survival. For instructional purposes, the book provides case studies, interesting facts, techniques etc. which help in showcasing the inter-disciplinary nature and bridge the gap between various aspects of applied microbiology.
Contents:
Bacterial Growth
Transport
Central Metabolic Pathways and Their Regulation
Electron Transport and Energy Generation
Metabolic Diversity of Carbon and Energy Source in Prokaryotes
Nitrogen Metabolism
Lipid Metabolism
Cell Wall Biosynthesis
Metabolism of Nucleotides
Secondary Metabolism
Response to Environmental Signaling. - DigitalJuan Pekolj, Victoria Ardiles, Juan Glinka, editors.Summary: Bile duct injuries (BDI) are considered the most serious surgical complication associated with cholecystectomy. According to different reports, its incidence has remained constant over the years, ranging from 0.1% to 0.9%. BDI is associated with a greater risk of perioperative morbidity and mortality, a reduction in the quality of life, and a decrease in long-term survival. Also, this complication is a concern to surgeons since its progression is uncertain and may lead to demands on professional responsibility ("malpractice") and emotional and physical consequences ("second victim"). Given that injuries in a high percentage of patients are initially unsuspected, the postoperative recovery may be prolonged, and the possibility of a successful repair reduced. Several surgical, endoscopic, and percutaneous procedures may be necessary to manage the lesions and to treat coexisting complications. BDI patients often undergo several repair attempts before successful resolution. This affects their quality of life and has a high psychological, physical, and mental impact due to the prolonged, complex, and unexpected nature of the injury. This currently represents a frequent problem in specialized referral centers or hepatobilopancreatic surgery units, where patients arrive with the sequelae of previous inadequate treatments. Usually, these patients require more elaborate procedures such as reoperations, liver resections and liver transplantation. The prevention, early diagnosis, and adequate treatment in the first approach is of crucial importance to ensure good long-term results. Therefore, this book is an essential resource for surgeons who perform cholecystectomy or treat BDI patients. It provides practical information and a comprehensive review on prevention and proper management, including complex cases. Readers will find contributions by experienced authors from a multidisciplinary and reference team in the management of BDI patients.
Contents:
Chapter 01: Introduction
Chapter 02: Anatomical Considerations
Chapter 03: Prevention
Chapter 04: Essential aspects BDI management
Chapter 05: Physiopathology of BDI
Chapter 06: Classification of BDI
Chapter 07: Intraoperative Diagnosis and Treatment
Chapter 08: Postoperative diagnosis of BDIs
Chapter 09: Role of imaging
Chapter 10: Assessment of vascular structures in BDIs
Chapter 11: Postoperative Treatment
Chapter 12: Role of percutaneous procedures
Chapter 13: Role of Endoscopic Procedures
Chapter 14: Role of Laparoscopy
Chapter 15: Biliodigestive Anastomoses
Chapter 16: Liver Resections
Chapter 17: Liver Transplantation. - DigitalDavid DiTullio, Medical student, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, Esteban C. Dell'Angelica, PhD, Professor, Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.Digital Access
- DigitalRebecca Sheets.Summary: Fundamentals of Biologicals Regulation: Vaccines and Biotechnology Medicines serves as an introduction to the international regulatory arena in which biologicals are developed and offers an overview of the processes and insight into the scientific concepts underpinning global regulations. This book will provide multiple levels of readership with guidance on basic concepts, a detailed look at regulatory challenges, and practical insight into how regulators consider regulatory science and regulatory process issues across various regions. With numerous case studies, learning activities, and real-world examples across several classes of biotechnological products, this book is a valuable and comprehensive resource for graduate students, professors, regulatory officials, and industry scientists working with biologicals.Digital Access ScienceDirect 2018
- PrintBernard Rosner, Harvard University.
- DigitalW. Richard Webb, William E. Brant, Nancy M. Major.Contents:
Introduction to CT of the thorax : chest CT techniques
Mediastinum : introduction and normal anatomy
Mediastinum : vascular abnormalities and pulmonary embolism
Mediastinum : lymph node abnormalities and masses
The pulmonary hila
Lung disease
Pleura, chest wall, and diaphragm
Introduction to CT of the abdomen and pelvis
Peritoneal cavity, vessels, nodes, and abdominal wall
Abdominal trauma
Liver
Biliary tree and gallbladder
Pancreas
Spleen
Kidneys and ureters
Adrenal glands
Gastrointestinal tract
Pelvis
CT in musculoskeletal trauma
CT in musculoskeletal nontrauma.Digital Access ClinicalKey 2020 - Digital/PrintChristopher G. Roth, MD, Associate Professor, Vice Chair, Quality and Performance, Vice Chair, Methodist Hospital Division, Department of Radiology, Thomas Jefferson University, Philadelphia, Pennsylvania, Sandeep Deshmukh, MD, Associate Professor, Division Director, Body CT, Medical Director, Jefferson Outpatient Imaging-Collegeville, Chairman, Residency Selection Committee, Department of Radiology, Thomas Jefferson University, Philadelphia, Pennsylvania.Contents:
Introduction and physics of body MRI
MRI of focal liver lesions
MRI of diffuse liver disease
MRI of the biliary system and gallbladder
MRI of the pancreas and spleen
MRI of the kidneys, ureters, and urinary bladder
MRI of the adrenal glands and retroperitoneum
MRI of the gastrointestinal system
MRI of the uterus and vagina
MRI of the ovaries and adnexa
MRI of the prostate and male genitourinary system.Digital Access ClinicalKey 2017 - Digital/PrintAndrew Leitner, Christine Chang, editors.Summary: This book presents a timely and multidisciplinary update on the modalities currently available for treating the most feared symptom of patients diagnosed with cancer. The various cancer pain syndromes are explored in detail, covering those related directly to malignancy and those due to the after-effects of cancer therapy. Treatment modalities, including pharmacologic approaches, interventional procedures, and palliative surgical options, are discussed clearly and concisely, with provision of recommendations for the practitioner. Further topics include new and emerging treatments for cancer pain, survivorship considerations, pain management in special populations, and implementation of systems-based pain programs. The book has been written by a multidisciplinary group of experts, reflecting the evolution in pain and symptom management that has occurred in parallel with progress toward more targeted oncologic treatments. Oncologists, palliative care physicians, allied health professionals, and other practitioners involved in caring for cancer patients will find Fundamentals of Cancer Pain Management to be a rich source of evidence-based insights into effective pain management.
Contents:
Part I: Background and Assessment of Cancer Pain, History and Epidemiology of Cancer Pain
Cancer Pain Syndromes
Cancer Treatment-Related Pain
Cancer Pain Management: A European perspective
Pain in the Cancer Survivor
Part II: Pharmacologic Therapies, Opioid therapy in cancer pain
Opioid related side effects and management
Clinical implications of opioid therapy
Non-Opioid Analgesics and Emerging Therapies
Part III: Interventional and Locoregional Therapies, Palliative Radiation for Cancer Pain Management
Ablation Techniques in Cancer Pain
Interventional Treatments for Cancer Pain
Peripheral nerve entrapments
Intrathecal Analgesia in Cancer Pain
Neurosurgical Treatments for Cancer Pain
Part IV: Total Pain and Rehabilitation, Physical Medicine and Rehabilitation
Psychosocial Aspects of Cancer Pain
Integrative Therapies in Cancer Pain. - DigitalDavid Alberts, Lisa M. Hess, editors.Contents:
Introduction to cancer prevention
Assessing human and economic benefits of cancer prevention
The role of diet, physical activity, and body composition in cancer prevention
Innate and adaptive immune responses to cancer
Hereditary risk for cancer
Cancer health disparties
Human categories and health : the power of the concept of ethnicity
Complementary and alternative approaches to cancer prevention
Telemedicine, telehealth, and e-health technologies in cancer prevention
Global cancer prevention
Sunscreen-based skin protection against solar insult : molecular mechanisms and opportunities
Skin cancer prevention
Prevention of colorectal cancer
Lung cancer prevention
Breast cancer prevention
Prevention of prostate cancer
Cervical cancer prevention
Ovarian cancer prevention
Endometrial cancer prevention
Cancer survivorship.Digital Access Springer 2014 - DigitalDavid S. Alberts, Lisa M. Hess, editors.Summary: This authoritative work, now in its fourth edition, presents state of the art knowledge on all key aspects of cancer prevention. In addition to detailed summaries on preventive strategies for specific cancers, readers will find current knowledge on a range of relevant scientific topics including the benefits of cancer prevention, the importance of diet and physical activity, innate and adaptive immune responses to cancer, hereditary risks, cancer health disparities, and the preventive role of telemedicine. In this new edition of the book, the coverage has been expanded to include additional disease sites and to provide up-to-date information across the range of disciplines in the field of cancer prevention and control. Written as a collaborative work by internationally recognized leaders in the field, Fundamentals of Cancer Prevention is an essential reference guide and tool for oncologists, primary care physicians, the research community, and students with an interest in reducing the burden of cancer through the implementation of effective preventive strategies.
Contents:
Introduction to Cancer Prevention
Assessing the Humanistic Benefits of Cancer Prevention
Assessing the Economic Outcomes of Cancer Prevention
The Role of Diet, Physical Activity, and Body Composition in Cancer Prevention
Innate and Adaptive Immune Responses to Cancer
Hereditary Risk for cancer
Cancer Health Disparities
Human Categories and Health the power of the concept of ethnicity
Complementary and alternative approaches to cancer prevention
Telemedicine, Telehealth, and eHealth technologies in cancer prevention
Global Cancer Prevention
Topical skin protection against solar insult molecular mechanisms and opportunities
Skin Cancer Prevention
Colorectal Cancer Prevention
Lung Cancer Prevention
Breast Cancer Prevention
Prostate Cancer Prevention
Cervical Cancer Prevention
Endometrial cancer Prevention
Ovarian Cancer Prevention
Cancer Survivorship. - DigitalJerry L. Workman, Susan M. Abmayr, editors.Summary: Chromatin is the combination of DNA and proteins that make up the genetic material of chromosomes. It is essential for packaging DNA, regulation of gene expression, DNA replication and repair. The audience for this book includes newly established scientists, graduate students and scientists seeking detailed overviews of various aspects of chromatin structure and function to gain entry into this field. The chapters in this book give a strong, updated groundwork about the fundamentals of chromatin which are essential to understand epigenetics. Some the fundamentals that this book covers include the structure and biochemistry of chromatin and the enzyme complexes that manage it.
Contents:
Preface
Histone, Nucleosome and Chromatin Structure
Histone Chaperones in the Assembly and Disassembly of Chromatin
Chromatin Remodeling Complexes
Regulating Chromatin by Histone Acetylation
Histone Methylation in Chromatin Signaling
Histone Ubiquitylation Control of Gene Expression
Regulation of Chromatin Structure and Function by PARP-1 and ADP-ribosylation
Histone phosphorylation and chromatin dynamics
Reading histone modifications
Properties and functions of histone variants
Transcription through Chromatin
Chromatin remodeling in DNA repair and replication
Heterochromatin: A Critical Part of the Genome
Emerging Areas of Chromatin Research
Index.Digital Access Springer 2014 - PrintJanine M. Bernard, Syracuse University, Rodney K. Goodyear, University of Redlands.Summary: "Fundamentals of Clinical Supervision, 5/e offers a comprehensive, interdisciplinary presentation that makes it the most highly cited publication in the field. Addressing essential topics for supervisors, it has earned a reputation as an authoritative resource for anyone seeking certification as an Approved Clinical Supervisor. Emphasizing central themes from a variety of mental health professions, the book covers supervision models, supervision modalities, administrative issues and professional concerns. This Fifth Edition covers the latest research, more on second-generation models of supervision, a new section on triadic supervision, and the latest on technology. Its one-of-a-kind supervision toolkit, scholarly approach, and topic coverage sets the book apart"--Publisher's website.
Contents:
Part I. Introduction and General Approaches to Supervision: 1. Introduction to clinical supervision
2. Supervision models
Part II. Dimensions of the Supervision Relationship: 3. Processes and issues of the supervisory triad and dyad
4. Supervisee and supervisor factors affecting the relationship
5. Multicultural supervision
Part III. The Delivery of Clinical Supervision: 6. Organizing the supervision experience
7. Individual supervision
8. Group supervision
9. Live supervision
Part IV. Professional Responsibilities of Clinical Supervisors: 10. Evaluation
11. Ethical and legal foundations for supervision practice
Part V. Promoting the Specialty of Clinical Supervision Through Training and Research: 12. Teaching and researching supervision. - DigitalLawrence M. Friedman, Curt D. Furberg, David L. DeMets, David M. Reboussin, Christopher B. Granger.Contents:
Introduction to Clinical Trials
Ethical Issues
What is the Question?
Study Population
Basic Study Design
The Randomization Process
Blinding
Sample Size
Baseline Assessment
Recruitment of Study Participants
Data Collection and Quality Control
Assessment and Reporting of Harm
Assessment of Health Related Quality of Life
Participant Adherence
Survival Analysis
Monitoring Committee Structure & Function
Statistical Methods Used in Interim Monitoring
Issues in Data Analysis
Closeout
Reporting and Interpreting of Results
Multicenter Trials
Regulatory Issues.Digital Access Springer 2015 - Digital[edited by] Marc S. Micozzi ; with forewords by C. Everett Koop, Aviad Haramati, and George D. Lundberg.Summary: Get a solid, global foundation of the therapies and evidence-based clinical applications of CAI. Fundamentals of Complementary, Alternative, and Integrative Medicine, 6th Edition is filled with the most up-to-date information on scientific theory and research of holistic medicine from experts around the world. The 6th edition of this acclaimed text includes all new content on quantum biology and biofields in health and nursing, integrative mental health care, and homeopathic medicine. Its wide range of topics explores therapies most commonly seen in the U.S., such as energy medicine, mind-body therapies, and reflexology along with traditional medicine and practices from around the world. With detailed coverage of historic and contemporary applications, this text is a solid resource for all practitioners in the medical, health, and science fields! -- Provided by publisher.
Contents:
Foundations of complementary / alternative medicine in health care
Fundamental sciences
Mind-body medicine
Bodywork and manual therapies
Western electromagnetic, natural, nutritional, and plant-based therapies
Traditional world medical systems part 1 : East and Southeast Asia
Traditional world medical systems part 2 : Middle Asia
Traditional world medical systems part 3 : Africa, Americas, and the Pacific.Digital Access ClinicalKey Nursing 2019 - DigitalLavakumar, Mallika.Contents:
Intro; Contents; Preface; Acknowledgments; Chapter 1; Neurocognitive and Neurological Examination; Introduction; Approach to the Consultation; History Gathering; Patient Interview; Cognitive Testing; Consciousness; Language; Orientation; Attention; Memory; Praxis; Executive Function; Brief Cognitive Batteries; The Neurological Examination; Sensory Function; Motor System; Coordination; Abnormal Movements; Reflexes; Special Topics; Conversion Disorder; Evaluation of Gait; Conclusion; Questions; Answers; References; Chapter 2; Neuromedical Procedures; Introduction Brain Imaging in Consultation Liaison Psychiatry Brain Imaging; Brain CT Scan; Brain MRI; Functional Brain Imaging Techniques; Single Proton Emission CT; Positron Emission Tomography; Functional MRI; Laboratory Testing in Consultation Liaison Psychiatry; Electrolytes; Complete Blood Count; Liver Function Abnormalities; Vitamin Deficiencies; Endocrine Abnormalities; Rheumatologic Diseases; Human Immunodeficiency Virus (HIV); Syphilis; Hepatitis C; Tuberculosis; Urinalysis; Urine Drug Screen; Other Conditions and Tests to Consider; Lyme Disease; Wilson's Disease Paraneoplastic Limbic EncephalitisAnti-NMDAR Encephalitis; Hashimoto's Encephalopathy or Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis; CSF Studies; Electroencephalography (EEG); Altered Mental Status; Paroxysmal Neurologic Events; Functional Seizures; Other Indications for EEG in Neuropsychiatry; Psychosis; Catatonia; Conclusion; Questions; Answers; References; Chapter 3; Neuropsychological Consultation; Introduction; Neuropsychological Assessment; Cognitive Domains and Assessment Measures; Orientation Attention, Processing Speed, Working Memory, and Executive FunctionsSpeech and Language; Visuospatial Function; Memory; Motor Function; Screening Measures; Intelligence; Premorbid Estimation; Psychological Functioning, Behavioral Status, and Effort; Neuropsychological Profiles of Common Neurological and Psychiatric Conditions; Stroke and Traumatic Brain Injury; Normal Pressure Hydrocephalus, Neoplasm, and Epilepsy; Dementias and Prion Disease; Delirium and Autoimmune Encephalitis; Substance Use and Other Psychiatric Conditions; Conclusion; Questions; References; Chapter 4; Delirium Introduction Delirium Subtypes; Pathophysiology; Morbidity and Mortality; Delirium Through the Continuum of Care; Emergency Department; Intensive Care Unit; Medical and Surgical Units; Home Care and Nursing Home; Palliative Medicine; Screening; Risk Factors and Evaluation; Delirium Management; Nonpharmacologic Interventions; Pharmacological Interventions; Antipsychotics; Alpha-2 Adrenergic Agonists; Valproic Acid; Melatonin; Benzodiazepine-Sparing Protocols for Alcohol and Sedative Withdrawal; Prevention; Nonpharmacologic Interventions; Pharmacologic Prevention; Anesthesia InterventionsDigital Access ProQuest Ebook Central 2019 - Digitaledited by Mallika Lavakumar, Lisa Rosenthal, and Terry Rabinowitz.Digital Access ProQuest Ebook Central 2019
- DigitalUlrich Meyer, editor.Summary: This is the first volume in an interdisciplinary three-book series covering the full range of biological, clinical, and surgical aspects in the evaluation, diagnosis, and treatment of patients with craniofacial malformations. This volume opens by considering general topics such as developmental biology and disease classification and then examines in depth the biological basis of the various malformations, including craniosynostoses, cleft-lip and palate with complex orofacial clefts, branchio-oculo-facial syndromes, rare syndromes, soft tissue malformations, and dysgnathia. Psychological aspects, including psychological evaluation methods and therapies and quality of life issues, are then addressed. Finally, all relevant clinical, radiological, and genetic investigations are described and important diagnostic issues are explored. Featuring numerous high-quality illustrations, the book will be of high value for all clinicians, researchers, and postgraduate students who deal with these malformations. The accompanying two volumes describe treatment principles and present in an atlas manner all relevant surgical techniques in detail with the aid of accompanying videos. The content of this multivolume set, written by the world's leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this medical field.
Contents:
Introduction. I General aspects: 1. Normal craniofacial development
2. Developmental biology of the face
3. Animal models of facial development
4. Anthrophosophical aspects of facial development
5. Pathological approaches for craniofacial diseases
6. Classification of craniofacial malformations. II Biological basis of disease: 7. Chromosomal aberrations
8. Orofacial clefts
9. Craniosynostoses
10. Branchio-oculo-facial syndromes
11. Conjoined twins
12. Craniofacial Soft tissue malformations
13. Postural head deformations
14. Dysgnathias
15. Rare craniofacial syndromes. III Psychological aspects of disease: 16. Facial appearance and the psychological impact
17. Psychological evaluation methods for patients with craniofacial malformations
18. Psychological therapies for patients with craniofacial malformations
19. Psycho-social impact of craniofacial malformations on treatment and outcome
20. Evolution of Craniofacial Surgery
21. Quality of life aspects of craniofacial malformations
22. Long term outcome of craniofacial surgery
23. Benchmarking and cost assessment of craniofacial surgery
24. Medical and malpractice claims in craniofacial surgery. IV Diagnostic issues: 25. Clinical Investigations of craniofacial malformations
26. Interdisciplinary approach to the treatment of craniofacial malformations
27. Craniomaxillofacial investigation
28. Neurosurgical investigation of craniofacial malformations
29. ENT investigation of craniofacial malformations
30. Ocular investigation of craniofacial malformations
31. Radiological Investigations of craniofacial malformations
32. Genetic investigations of craniofacial malformations
33. Speech issues in patients with craniofacial malformations
34. Feeding issues in patients with craniofacial malformations
35. Breathing disorders in patients with craniofacial malformations. - DigitalJanna Gordon-Elliott.Contents:
Patients who eat too little. Arlene, an anxious young woman
Becky's body worries
Cassandra, the college student
Danny, the picky eater
Eric, the hopeful Olypian
Francine's insulin issues
Patients who eat too much. Ginny, the secret eater
Hannah's troubles
Ian, the guilty eater
James, the inconsistent eater
Kendra's social anxiety
Lisa, overweight but undernourished
Patients who eat in odd ways. Mimi, the quiet little girl
Nilda's food allergies
Olive, the healthy eater
Peter, healthy weight but unhealthy.Digital Access Springer 2017 - DigitalJohn P. McGahan, Michael A. Schick, Lisa D. Mills.Contents:
Physics, machine and technique
Artifacts
Peritonsillar abscess
Neck masses
Ocular
Carotid artery
Cranial
Lungs
Transthoracic echocardiography
Pediatric transthoracic echocardiography
Transesophageal echocardiography
Approach to the patient with shortness of breath
Approach to the patient with chest pain
Ultrasound-guided resuscitation
FAST of the abdomen, beyond basics: false positives, limitations, and approach to the unstable patient
Liver and spleen
Gallbladder and biliary
Pancreas
Kidney and renal transplant
Abdominal aorta
Lower abdomen and bowel
Male pelvis
Female pelvis, nonpregnant
Female pelvis, pregnant - first trimester
Female pelvis, pregnant - second/third trimester
Peripheral veins and arteries
Soft tissue
Musculoskeletal
Ultrasound-guided procedures
Venous access
Nerve blocks.Digital Access ClinicalKey 2020 - DigitalFrancesco Chiappelli.Contents:
Fundamental Implications for Clinical Practice
Translational Effectiveness in the Context of Translational Science
Comparative Effectiveness Analysis and Evidence-Based Decisions
Methodology I: The Best Available Evidence
Methodology II: Sampling and Assessment of the Evidence
Methodology III: Systematic Evaluation of the Statistical Analysis: Data Analysis in Research Synthesis
Optimizing Clinical Practice-Based Patient-Centered Outcomes Research
Getting and Understanding Data
Obtaining Data
Describing and Analyzing Data
Translational Effectiveness Analysis
Optimizing Clinical Outcomes by Individualizing Observations
Evaluation in Patient-Centered Outcomes Research
Translational Effectiveness in Practice-Based Patient-Centered Outcomes Research.Digital Access Springer 2014 - DigitalMax M. Houck, Jay A. Siegel.Summary: Fundamentals of Forensic Science, Third Edition, provides current case studies that reflect the ways professional forensic scientists work, not how forensic academicians teach. The book includes the binding principles of forensic science, including the relationships between people, places, and things as demonstrated by transferred evidence, the context of those people, places, and things, and the meaningfulness of the physical evidence discovered, along with its value in the justice system. Written by two of the leading experts in forensic science today, the book approaches the field from.
Contents:
Section I. Criminal Justice and Forensic Science; CH1 The Practice of Forensic Science
CH2 Crime Scene Investigation
CH3 The Nature of Evidence; Section II. Analytical Tools; CH4 Microscopy
CH5 Light and Matter
CH6 Separation Methods; Section III. Biological Sciences; CH7 Pathology
CH8 Anthropology and Odontology
CH9 Entomology
CH10 Serology and Bloodstain Pattern Analysis
CH11 DNA Analysis
CH12 Forensic Hair Examinations; Section IV. Chemical Sciences; CH13 Illicit Drugs
CH14 Forensic Toxicology
CH15 Textile Fibers
CH16 Paint Analysis
CH17 Soil and Glass
CH18 Fires and Explosions; Section V. Physical Sciences; CH19 Friction Ridge Examination
CH20 Questioned Documents
CH21 Firearms and Toolmarks
CH22 Impression Evidence
CH23 Forensic Engineering
CH24 Digital Evidence and Computer Forensics; Section VI. Legal and Forensic Science; CH25 Legal Aspects of Forensic Science.Digital Access ScienceDirect 2015 - DigitalFrancesco Palazzo, editor ; with contribution by Michael J. Pucci.Summary: This book provides a comprehensive guide to the surgical skills required during general surgery. General Concepts are covered with descriptions of basic terminology, the logic behind specific approaches, limitations of specific skills, technical and practical considerations, and safety of using specific approaches and skills. More advanced topics including gastro-intestinal anastomosis, exploring a patient after a major trauma, and managing crisis situations are also discussed, as well as current controversies and future directions within general surgery. Fundamentals of General Surgery is relevant to trainees in general surgery and its subspecialties, and aims to give them an easy to access resource that contains real life examples, iconography, and recommended further reading.
Contents:
Foreword
Preface
Fundamentals of patient preparation for the operating in the 21st century
Fundamentals of Operating room setup and surgical instrumentation
Fundamentals of Surgical Sutures and Associated Technical skills
Fundamentals of Patient Positioning and Skin Prep
Fundamentals of incisions and skin closures
Fundamentals of retractors and exposure
Fundamentals of dissection
Fundamentals of Surgical Hemostasis
Fundamentals of energy utilization in the Operating room
Fundamentals of Stapling devices
Fundamentals of Drain management
Fundamentals of endoscopy for the general surgeon
Fundamentals on prosthetic materials for the abdominal wall
Fundamentals of basic laparoscopic setup
Fundamentals of laparotomy closure
Fundamentals of Robotic Surgery
Fundamentals of gastro
intestinal anastomosis
Fundamentals of vascular anastomosis
Appendix on common vascular instruments
Fundamentals of exploratory laparotomy for Trauma
Fundamentals of temporary abdominal wall closure
Fundamentals of exploratory thoracotomy for Trauma
Fundamentals of becoming a safe and independent surgeon (from first assistant to skilled educator)
Fundamentals of acceptable behavior in the OR (etiquette)
Fundamentals of the daily routine as a surgeon
Fundamentals of managing the operative catastrophe. - PrintGregory S. Ogrinc MD, MS, Linda A. Headrick, MD, MS, Amy J. Barton, PhD, RN, FAAN, ANEF, Mary A. Dolansky, PhD, RN, FAAN, Wendy S. Madigosky, MD, MSPH, FAAFP, Rebecca S. (Suzie) Miltner, PhD, RN, FAAN, Allyson G. Hall, PhD, MBA/MHS ; foreword by Kedar Mate, MD.Summary: Fundamentals of Health Care Improvement: A Guide to Improving Your Patient's Care, 4th edition, is intended to help health professional learners diagnose, measure, analyze, change, and lead improvements in health care, with the aim to shape reliable, high-quality systems of care in partnership with patients. Co-published by Joint Commission Resources and the Institute of Healthcare Improvement, this fourth edition includes updated resources, including examples, figures, tables, and tools. New to this edition is a focus on health equity and disparities of care brought to light by the COVID-19 pandemic. This focus explores the relationship between social determinants of health and how improvement methods and skills can help identify and close disparity gaps in systems of care. Also new to this edition is an expanded discussion of effective teamwork and the importance of creating multidisciplinary health care teams that partner with patients and families. -- Provided by publisher.
Contents:
Identifying gaps in quality and working in teams to close those gaps
Finding scientific evidence for clinical improvement
Identifying a focus for improvement
Process literacy, culture, context, and systems in health care
Measurement part 1: data analysis for decision making in health care
Measurement part 2: using run charts and statistical process control charts to gain insight into systems
Understanding and making changes in a system
Spreading improvements
Publishing and presenting quality improvement
Appendix: Tools to help your improvement work.Digital Access R2Library [2022], ©2022 - DigitalGiovanni Cavagna.Summary: This textbook explores the fundamental qualitative and quantitative aspects of human physiology. It approaches biological and physiological processes and phenomena from a quantitative perspective, revealing how physiological problems can be mathematically formulated starting from simple laws of physics. The book addresses a broad range of topics, including: the statics and dynamics of circulation; muscle and sarcomere force-length and force-velocity relations, together with their mechanisms and functional consequences; subdivisions and meaning of the heat produced by muscle; locomotion, statics and dynamics of respiration; diffusion of gases and acid base equilibrium; phonation; general functions of the kidney and of the different sections of the nephron; changes in clearance with a substances plasmatic concentration; pH regulation and the kidney; Donnans equilibrium and its consequences; and the Nernst equation. The book offers the ideal learning resource for students of human physiology courses in medicine and biomedicine, as well as biomedical engineering and biophysics graduate students. An elementary grasp of mathematics and physics is sufficient to understand the content.
Contents:
Circulation of blood
Muscle, locomotion and heart
Respiration
Kidney.Digital Access Springer 2019 - Print[edited by] Carla Jackie Sampson, Bruce J. Fried.Summary: "The third edition of Fundamentals of Human Resources in Healthcare is updated to include the contemporary issues in healthcare HR made more urgent by the Great Resignation and resulting shockwaves to the employer-employee relationship. This edition includes a new chapter on Employee Well Being and a revamped chapters on Organizational and Employee Development, Diversity, Inclusion, and Belonging, and Aligning Quality Improvement and Implementation Science with HR Practices"-- Provided by publisher.
Contents:
Strategic Human Resources Management / Carla Jackie Sampson
The Healthcare Professional / Patrick D. Shay and Dolores G. Clement
The Legal and Ethical Environment / Drake Maynard
Job Analysis and Job Design / Sean N. Newman and Paige N. Ocker
Recruitment, Selection, and Retention / Gabriela "Gabbi" J. Maris and Bruce J. Fried
Organizational and Employee Development / Carla Jackie Sampson and Julene Campion
Performance Management / Bruce J. Fried
Compensation Practices, Planning, and Challenges / Bruce J. Fried, Brigid K. Grabert, and John Cashion
Employee Benefits / Melissa G. McCraw and Dolores G. Clement
Organized Labor / Carla Jackie Sampson, Bruce J. Fried, and Donna Malvey
Diversity, Inclusion, and Belonging in the Workplace / Carla Jackie Sampson, Bruce J. Fried, and Jeffrey Simms
Applying Quality Improvement and Implementation Science in Human Resources Practices / Hilary K. Hecht and Bruce J. Fried
Employee Well-Being / Amanda Raffenaud and Tina Yeung.Digital Access R2Library [2023] - DigitalReza Borhani, Soheila Borhani, Aggelos K. Katsaggelos.Summary: This book provides an accessible introduction to the foundations of machine learning and deep learning in medicine for medical students, researchers, and professionals who are not necessarily initiated in advanced mathematics but yearn for a better understanding of this disruptive technology and its impact on medicine. Once an esoteric subject known to few outside of computer science and engineering departments, today artificial intelligence (AI) is a widely popular technology used by scholars from all across the academic universe. In particular, recent years have seen a great deal of interest in the AI subfields of machine learning and deep learning from researchers in medicine and life sciences, evidenced by the rapid growth in the number of articles published on the topic in peer-reviewed medical journals over the last decade. The demand for high-quality educational resources in this area has never been greater than it is today, and will only continue to grow at a rapid pace. Expert authors remove the veil of unnecessary complexity that often surrounds machine learning and deep learning by employing a narrative style that emphasizes intuition in place of abstract mathematical formalisms, allowing them to strike a delicate balance between practicality and theoretical rigor in service of facilitating the readers learning experience. Topics covered in the book include: mathematical encoding of medical data, linear regression and classification, nonlinear feature engineering, deep learning, convolutional and recurrent neural networks, and reinforcement learning. Each chapter ends with a collection of exercises for readers to practice and test their knowledge. This is an ideal introduction for medical students, professionals, and researchers interested in learning more about machine learning and deep learning. Readers who have taken at least one introductory mathematics course at the undergraduate-level (e.g., biostatistics or calculus) will be well-equipped to use this book without needing any additional prerequisites.
Contents:
Introduction
Mathematical Modeling of Medical Data
Linear Learning
Nonlinear Learning
Multi-Layer Perceptrons
Convolutional Neural Networks
Recurrent Neural Networks
Autoencoders
Generative Adversarial Networks
Reinforcement Learning. - DigitalSherman Silber, MD.Summary: This book analyzes the basic science and treatment of male factor infertility with Dr. Silber's characteristic honesty and clear thinking. It describes finally what works and what doesn't work. It will inspire everyone in reproductive medicine (Gynecologists, Urologists, Embryologists and Endocrinologists) who wish to better understand male infertility.Digital Access Springer 2018
- DigitalJon A. Jacobson.Contents:
Basic pathology concepts
Shoulder ultrasound
Elbow ultrasound
Wrist and hand ultrasound
Hip and thigh ultrasound
Knee ultrasound
Ankle, foot, and lower leg ultrasound
Interventional techniques.Digital Access ClinicalKey 2018 - DigitalLarry E. Davis, Sarah Pirio Richardson.Contents:
Approach to the patient with neurologic problem: key steps in neurological diagnosis and treatment
Neurologic examination
Common neurologic tests
Disorders of muscle
Disorders of the neuromuscular junction
Disorders of peripheral nerves
Disorders of the spinal cord and vertebral bodies
Disorders of the brainstem and cerebellum
Disorders of the cerebrovascular system
Disorders of myelin
Disorders of higher cortical function
Disorders of the extrapyramidal system
Infections of the Nervous System
Brain tumors
Seizures and status epilepticus
Cardiac arrest, coma and cerebral death
Disorders of the developing nervous system
Traumatic brain injury and subdural hematoma
Neurologic complications of alcohol and B12 deficiency
Disorders of pain and headache
Disorders of the vestibular system
Sleep. - DigitalHeinrich Mattle, Marco Mumenthaler ; with assistance from the Institute for Diagnostic and Interventional Neuroradiology, Inselspital, University of Bern, Bern, Switzerland, Professor Jan Gralla, Professor Gerhard Schroth ; translated and adapted by Ethan Taub.Summary: "The second edition of this practical guide provides a thorough introduction to the essential concepts of clinical neurology. Coverage includes history-taking; the neurological examination and ancillary tests; topical diagnosis and differential diagnosis of typical syndromes; the diseases of the central nervous system, peripheral nerves, autonomic nervous system, and muscles; epilepsy; and inflammatory diseases such as multiple sclerosis. Central to the book are the lucid structuring of complex contents allowing efficient learning, even without prior knowledge of the subject; and the vital link between theory and clinical practice, with essential information on history-taking, the clinical examination, and additional tests, all supported by informative graphics and appropriate computed tomography or magnetic resonance imaging studies. Key Features: - Brilliant format and structure, making the assimilation of complex information easy and efficient - Clear color illustrations and graphics, many new or revised for the second edition - Comprehensive tables expand and organize information on many topics - New to the second edition: complete revision of contents and an enhanced layout - Vast clinical experience of two highly respected university teachers Fundamentals of Neurology: An Illustrated Guide is the ideal introduction to clinical neurology for medical students, physical therapists, and other professionals involved in patient care"--Provided by publisher.Digital Access Thieme MedOne Education 2017
- DigitalAndrei Fernandes Joaquim, Enrico Ghizoni, Helder Tedeschi, Mauro Augusto Tostes Ferreira, editors.Summary: The aim of this book is to provide clinicians and medical students with basic knowledge of the most common neurosurgical disorders. There is a vast array of signs and symptoms that every clinician should recognize as neurosurgical affectations, allowing them to identify when to refer the patient to a neurosurgeon. In this text, the editors intend to bridge the gap between clinical medicine and neurosurgery, making neurosurgical practice understandable to a wider medical public. The book provides a smooth transition from neuroanatomy, neurophysiology and neurological examination to neurosurgery, focusing more on the knowledge underlying neurosurgical practice rather than on surgical technique. The core of the book is composed of chapters discussing each of the most important medical conditions that deserve neurosurgical intervention, providing key information on diagnosis, clinical aspects, disease management, surgical procedures and prognosis. Moreover, complementary discussion of the frontiers and advances in neurosurgery are also covered. In this sense, this book has two main goals and intended audiences. First, and primarily, it is intended for clinicians in a wide array of non-surgical medical specialties (such as general practitioners, neurologists, pediatricians, oncologists and others) aiming to give an overview on important characteristics and initial management of the most prevalent disorders treated by neurosurgeons. Second, and to a lesser degree, it is intended to be used as a practical guide for medical students who are initiating their study in neurosurgical sciences. Fundamentals of Neurosurgery - A Guide for Clinicians and Medical Students intends to be a comprehensive guide for all non-neurosurgeons who want to broaden their knowledge of neurosurgery. .
Contents:
Intro; Foreword; Preface; Acknowledgments; Contents; Contributors;
1: Neuroanatomy Applied to Clinical Practice; Introduction; Objective; The Central Nervous System; Morphological Aspects of the Encephalon or Telencephalon; The Brain; The Frontal Lobe; The Temporal Lobe; The Parietal Lobe; The Occipital Lobes; The Insular Lobes; The Limbic Lobe; The Diencephalon; The Basal Nuclei; The Cerebellum; The Brainstem; Vascularization; Suggested Readings and References;
2: Basic Neuroimaging; Computed Tomography; Magnetic Resonance Imaging (MRI); T1; T2; FLAIR; Fat Suppression T1 Postcontrast (Gadolinium)Advanced Sequences; Susceptibility Sensitive Sequence (T2, SWI); DWI and DTI; MR Perfusion-Weighted Imaging; Spectroscopy; Steady-State Gradient Echo Acquisition for CSF Cisternography (FIESTA, CISS); MR Angiography;
3: The Basic Neurological Examination; Introduction; Objective; Rationale for Diagnosis in Neurology/Neurosurgery; The Neurological Examination; Eloquent Brain Areas; Consciousness and Cognition; Gait and Balance; Muscular Examination; Sensory Evaluation; Pupil Examination; Coma; Cranial Nerves; Conclusion; Suggested Readings and References
4: Intracranial HypertensionDefinition; Background; Pathophysiology; Physical Examination and Clinical Features; Additional Work-Up and Monitoring; Treatment; General Management; First Level Measures; Second-Line Measures; Suggested Readings and References;
5: Traumatic Brain Injury Overview and Practice Parameters; Traumatic Brain Injury; Mechanism; Severity; Clinical Evaluation; First Step: Bedside Physical Exam; General Examination; Neurological Examination; Special Considerations in Examining TBI Patients; Pupils; Motor Function Imaging and Diagnostic Procedures First Steps and ConsiderationsComputed Tomography; Intracranial Lesions (Fig. 5.1a); Epidural Hematoma (Fig. 5.1b); Subdural Hematoma (Fig. 5.1c); Contusions/Intracerebral Hemorrhage (Fig. 5.1d); Penetrating Injury (Fig. 5.1e); Treatment; Medical Versus Surgical Management; Medical Therapy; Blood Pressure and Oxygenation; Airway; Cardiopulmonary; Hyperosmolar Therapy; Prophylactic Hypothermia; Infection Prophylaxis; Deep Venous Thrombosis Prophylaxis; Intracranial Pressure Monitoring; Intracranial Pressure Monitor Technology Treatment Thresholds and Optimal Cerebral Perfusion PressureBrain Oxygenation Monitoring and Threshold for Treatment; Anesthesia, Analgesics, and Sedatives; Nutrition; Antiseizure Prophylaxis; Hyperventilation; Steroids; Surgical Therapy; Indications for Surgery; Special Consideration: Surgery for Diffuse Brain Injury or ICP control; Special Considerations: Penetrating Head Injury; Ongoing Care Beyond Initial Interventions; Imaging Modalities That May Assist in Prognosis and Other TBI-Related Care; Computed Tomography Angiography; Magnetic Resonance Imaging; Clinical Electrophysiology - DigitalGopal B. Saha.Summary: Currently an estimated 17 million nuclear medicine procedures are performed each year in the US and constantly evolving, as new radiopharmaceuticals and imaging techniques are introduced for better diagnosis and treatment of human diseases. In keeping up with new developments, the Seventh Edition of Fundamentals of Nuclear Pharmacy chronicles the advancements in radiopharmaceuticals and their use in clinical applications. It discusses basic concepts such as the atom, radioactive decay, instrumentation and production of radionuclides, and explores the design, labeling, characteristics and quality control of radiopharmaceuticals. Radiation regulations and diagnostic and therapeutic applications of radiopharmaceuticals are detailed.Digital Access Springer 2018
- Print[edited by] Patricia A. Potter, Anne Griffin Perry, Patricia A. Stockert, Amy M. Hall.Summary: Textbook for Nursing Fundamentals, Complex Health Alterations, ADN Psych Clinical, Nursing Advanced Skills, and LPN/RN Refresher Skills.
- DigitalGary A. Ulaner.Summary: "In the fast-changing age of precision medicine, PET/CT is increasingly important for accurate cancer staging and evaluation of treatment response. Fundamentals of Oncologic PET/CT, by Dr. Gary A. Ulaner, offers an organized, systematic introduction to reading and interpreting PET/CT studies, ideal for radiology and nuclear medicine residents, practicing radiologists, medical oncologists, and radiation oncologists. Synthesizing eight years' worth of cases and lectures from one of the largest cancer centers in the world, this title provides a real-world, practical approach, taking you through the body organ by organ as it explains how to integrate both the FDG PET and CT findings to best interpret each lesion"--Publisher's description.
Contents:
Introduction to FDG PET/CT
FDG PET/CT performance and reporting
Skeleton on FDG PET/CT
Muscle and nerve on FDG PET/CT
Skin and breast on FDG PET/CT
Brain on FDG PET/CT
Head and neck on FDG PET/CT
Lung on FDG PET/CT
Pleura on FDG PET/CT
Heart on FDG PET/CT
Thymus masses on FDG PET/CT
Hepatobiliary FDG PET/CT
Spleen on FDG PET/CT
Pancreas on FDG PET/CT
Adrenal glands on FDG PET/CT
Gastrointestinal tract on FDG PET/CT
Peritoneum on FDG PET/CT
Urinary tract on FDG PET/CT (kidneys, ureters, bladder)
Female pelvis on FDG PET/CT
Male pelvis on FDG PET/CT
Lymph nodes on FDG PET/CT
Measuring treatment response on FDG PET/CT
Artifacts on FDG PET/CT
Radiotracers other than FDG for oncologic PET/CT.Digital Access ClinicalKey 2019 - DigitalJianguo Cheng, Richard W. Rosenquist, editors.Summary: Characterized by clarity and straddling the line between scope and depth of information, this concise book provides physicians a comprehensive overview of pain medicine. Chapters are written by some of the leading minds in pain medicine and feature case studies, key points and suggested readings. Multidisciplinary approaches to the clinical and financial challenges of pain with the goal of improving patient quality of life are also discussed. Additionally, the book is in is in tight alignment with the information that trainees are expected to master for the American Board of Anesthesiology's pain medicine subspecialty certification, as outlined by the Joint Council on Anesthesiology Examinations; it covers the diagnosis of pain states, the management of pain, acute pain, radicular pain, neuropathic pain, chronic visceral pain, headaches, and special populations. This book is a must-have for anyone new to pain medicine or studying for the subspecialty certification.Digital Access Springer 2018
- DigitalJ.D. Hoppenfeld, MD, Interventional Pain Management, Southeast Pain Care, Charlotte, North Carolina.Summary: "Some patients present with a primary complaint of pain while others complain of pain secondary to a more generalized disease process or procedure. As a healthcare professional, you are trained to diagnose the pathology and then treat it. A patient presents with pneumonia, your work-up supports the diagnosis; you treat it, then the patient gets better. However, another layer of patient care needs more focus in the medical community. If the patient with pneumonia complains of intercostal pain secondary to a violent cough, we have the ability to manage the symptoms of pain effectively, and should not hesitate to do so promptly. Our actions to alleviate pain will not hinder our ability to treat the underlying disease. Yet modern medicine often considers these goals mutually exclusive, with pain management a distance second. As medical professionals, when we have an incomplete understanding of how to treat a condition, we under treat it, erring on the side of do no harm. This book will give you the confidence to confront your patient's discomfort and succeed in conquering the pain"--Provided by publisher.Digital Access LWW Health Library 2014
- DigitalIftekhar Mahmood, Gilbert Burckart, editors.Contents:
1. Pediatric Drug Development and the Regulatory Changes That Are Creating the Science of Pediatric Dosing / Gilbert J. Burckart
2. Pediatric Physiology / Iftekhar Mahmood
3. Developmental Pharmacology: Impact on Pharmacokinetics and Pharmacodynamics
of Drugs / Iftekhar Mahmood
4. Pediatric Clinical Trial Design and Dosing / Dionna Green and Valerie Amspacher
5. Application of Allometric Principles in Pediatric Drug Development / Iftekhar Mahmood
6. Population Pharmacokinetics in Pediatric Drug Development / Jeremiah D. Momper , John Bradley , and Brookie M. Best
7. Scaling Dose-Exposure-Response from Adults to Children / Ine Skottheim Rusten , Anna Nordmark , Susan Cole , Joseph F. Standing , Sofi a Friberg Hietala , Wei Zhao , Valeria Gigante , Anna Karin Hamberg , Gérard Pons , María Jesús Garrido , Johannes Taminiau , Norbert Benda , Frederike Lentz , Flora Musuamba Tshinanu , Andrew Thomson , Paolo Tomasi , Cecile Ollivier , Ralf Herold , and Efthymios Manolis
8. Applications of Physiologically Based Pharmacokinetic (PBPK) Models for Pediatric Populations / Peng Duan , Jeffrey Fisher , and Jian Wang
9. Perinatal Pharmacology and Maternal/Fetal Dosing / Iftekhar Mahmood, Gilbert J. Burckart and Robert M. Ward.Digital Access Springer 2016 - Digital[edited by] Lane F. Donnelly, MD, Chief Quality Officer, Hospital-Based Services, Associate Radiologist-in-Chief, Department of Radiology, Texas Children's Hospital, Professor of Radiology, Baylor University College of Medicine, Houston, Texas.Contents:
Special considerations in pediatric imaging / Lane F. Donnelly
Airway / Lane F. Donnelly
Chest / Monica S. Epelman
Cardiac / Daniel J. Podberesky
Gastrointestinal / Lane F. Donnelly
Genitourinary / Monica S. Epelman
Musculoskeletal / Alexander J. Towbin
Neuro / Carolina V. Guimaraes.Digital Access ClinicalKey 2017 - DigitalGirija Prasad Rath, editor.Summary: The book provides an excellent review of all the clinical aspects of neuroanesthesia in children, including neurosurgeries during fetal state to neonatal, infancy, toddler, and school-going age groups. To provide optimal anesthetic care in children undergoing neurosurgery, the care provider must have adequate knowledge on the developing brain and spinal cord, and the effect of anesthetics on the neuronal tissue, and the inherent issues pertaining to neurologic lesions. This book covers the diagnostic, imaging, surgical as well as anesthetic managements of all the neurosurgical problems in children. The chapters include a wide range of topics from basic neurophysiology to general concerns for pediatric neuroanesthesia, including fluid management, blood transfusion, temperature regulation, and surgical positioning, as well as specific issues such as anesthesia for brain tumor surgery, hydrocephalus, neural tube defects, cerebrovascular surgeries such as aneurysmal surgery, arteriovenous malformations (AVMs), Moyamoya disease, and vein of Galen malformation, functional neurosurgery, epilepsy surgery, neuroendoscopy, craniovertebral junction anomalies, spinal surgeries, neurotrauma, and brain abscess with congenital heart diseases. Interesting topics like neuroanesthesia in remote locations, regional anesthesia during neurosurgery, and anesthesia for children with neuromuscular disease are also discussed. Moreover, the book elaborates on advanced neuroanesthesia techniques during fetal neurosurgery and craniopagus separation surgery; and the postoperative intensive care management aspects in each chapter. This book caters to neuroanesthesiologists, pediatric anesthesiologists, residents, and fellows of anesthesia or neuroanesthesia, practicing anesthesiologists, pediatric neurointensivists, nurse anesthetists, neurosurgeons, and pediatric neurosurgeons. It also serves as a reference book for the DM (neuroanesthesiology and neurocritical care), DNB-SS (neuroanesthesiology), and MD (anesthesiology) curriculums apart from anesthesia residency and pediatric anesthesia/ neurosurgery fellowship programs offered at various Institutions worldwide.
Contents:
Intro
Foreword
Preface
Acknowledgments
Contents
About the Editor
Part I: General Considerations
1: Pediatric Neuroanesthesia: Evolution of a New Subspeciality
1.1 Introduction
1.2 Development of Neuroanesthesia Along with Neurosurgery
1.3 Development of Pediatric Neurosurgery as a Subspecialty
1.3.1 Neurosurgery: An Indian Perspective
1.4 Pediatric Neuroanesthesia: Not Just "Anesthesia" or "Neuroanesthesia"
1.5 Future Prospects as a Subspeciality
1.6 Conclusion
References 2: Developmental Anatomy and Physiology of the Central Nervous System in Children
2.1 Introduction
2.2 Development of the Central and Autonomic Nervous Systems
2.2.1 Intrauterine Development
2.2.2 Development of the Brain
2.2.3 Development of the Spinal Cord
2.2.4 Autonomic Nervous System (ANS)
2.2.5 Neuronal and Cellular Proliferation
2.2.6 Myelination
2.3 Relevant Anatomy
2.3.1 Head Size, Suture, and Fontanelle
2.4 Cerebral Vascular Anatomy
2.4.1 Arterial Circulation
2.4.2 Venous Drainage
2.5 Cerebral Physiology 2.5.1 Cerebral Blood Flow (CBF)
2.5.1.1 Factors Affecting Cerebral Blood Flow
Cerebrovascular Reactivity to Carbon Dioxide in Children
2.5.2 Cerebral Metabolic Rate (CMR)
2.5.3 Cerebral Autoregulation (CA)
2.5.3.1 Cerebral Autoregulation (CA) in Neonates
2.5.3.2 Cerebral Autoregulation (CA) in Small Children
2.5.4 Cerebral Spinal Fluid (CSF) Dynamics
2.5.5 Blood-Brain Barrier (BBB)
2.5.6 Intracranial Pressure (ICP)
2.5.7 Cerebral Compliance (Intracranial Pressure-Volume Relationship)
2.5.7.1 Intracranial Compliance 2.6 Spinal Cord Anatomy and Physiology
2.6.1 Spinal Cord Vascular Anatomy
2.7 Neurotoxicity in the Immature Human Brain
2.8 Epileptogenesis in the Developing Brain
2.9 Neuroprotection
2.9.1 General Measures
2.9.2 Anesthetic Agents
2.9.3 Temperature Control: Therapeutic Hypothermia
2.9.4 Hypoxic-Ischemic Preconditioning
2.9.5 Remote Ischemic Preconditioning
2.9.6 Erythropoietin (EPO)
2.9.7 Progesterone
2.9.8 Neurotrophic Factors
2.9.9 Stem Cell Treatment
2.10 Cerebral Physiology in Pathological States
2.11 Conclusion
References 3: Effect of Sedatives and Anesthetics on Cerebral Physiology in Children
3.1 Introduction
3.2 Effect of Specific Anesthetic Agents
3.2.1 Inhaled Anesthetics
3.2.1.1 Nitrous Oxide
3.2.1.2 Halothane
3.2.1.3 Isoflurane
3.2.1.4 Sevoflurane
3.2.1.5 Desflurane
3.2.1.6 Xenon
3.2.2 Intravenous Anesthetics
3.2.2.1 Propofol
3.2.2.2 Thiopentone
3.2.2.3 Etomidate
3.2.2.4 Ketamine
3.2.3 Other Agents
3.2.3.1 Opioids
3.2.3.2 Benzodiazepines
3.2.3.3 Muscle Relaxants
3.2.3.4 Dexmedetomidine
3.3 Anesthetic Neuroprotection in Children
3.4 Conclusion. - DigitalLynn T. Staheli.Digital Access
- DigitalPeter Mattei, editor ; Peter F. Nichol, Michael D. Rollins, Christopher S. Muratore, associate editors.Digital Access Springer 2017
- DigitalPeter Mattei, editor.Contents:
Intro
Foreword
Preface
Acknowledgments
Contents
Contributors
Part I: Perioperative Care
1: Preoperative Assessment and Preparation
Risks of Anesthesia
Airway
Respiratory System
Cardiovascular System
Gastroesophageal Reflux Disease
Obesity
Diabetes
Thyroid Disease
Corticosteroids
Anemia
Sickle Cell Disease
Coagulation Disorders
Malignancy
Anterior Mediastinal Mass
Cerebral Palsy
Developmental Disorders
Prematurity
Malignant Hyperthermia
Hypotonia
Trisomy 21
Allergies
Prior to Admission Medications NSAIDs and Aspirin
Herbal Medications
Illicit/Recreational Medications
Preoperative Fasting
Laboratory Testing and Diagnostic Studies
Editor's Comments
Further Reading
2: Prenatal Diagnosis and Genetic Counseling
Maternal and Family History
Carrier Screening
Screening and Testing Options
Screening Throughout the Pregnancy
First Trimester
Serum Screening
Ultrasound
Second Trimester
Maternal Serum Quadruple Screen
Combined First- and Second-Trimester Serum Screening
Ultrasound
Diagnostic Testing
Chorionic Villus Sampling Second Trimester
Genetic Diagnostic Testing
Fluorescent in Situ Hybridization
Chromosome Analysis
Chromosomal Microarray Analysis
Molecular Testing
Whole Exome Sequencing
Summary
Editor's Comments
Further Reading
3: Neuraxial and Regional Anesthesia
Neuraxial Analgesia and Anesthesia
Epidural and Caudal Analgesia
Spinal Anesthesia
Truncal Anesthesia
Quadratus Lumborum
Erector Spinae
Peripheral Regional Anesthesia
Upper Extremity Regional Anesthesia
Lower Extremity Regional Anesthesia
Duration of Regional Anesthesia Special Considerations in the Pediatric Patient
Commonly Used Local Anesthetics
Local Anesthetic Toxicity
Conclusion
Editor's Comments
Further Reading
4: Positioning and Incisions
Positioning
Supine
Dorsal Lithotomy
Lateral Decubitus
Prone
Abdominal Incisions
Midline Abdominal Incision
Transverse Abdominal Incision
Low Transverse Incision
Subcostal Incision
Miscellaneous Abdominal Incisions
Thoracic Incisions
Sternotomy
Thoraco-Abdominal Incision
Other Incisions
Further Reading
5: Enteral Nutrition and Access Nutritional Requirements
Nutrition for Premature Infants
Short Bowel Syndrome
The Critically Ill Child
Enteral Access
Summary
Editor's Comments
Further Reading
6: Parenteral Nutrition
Nutrition Assessment
Calories
Carbohydrates
Protein
Protein Recommendations
Lipids
Intralipids
SMOF
Omegaven
Carnitine
Electrolytes
Sodium
Potassium
Calcium
Phosphorus
Magnesium
Trace Elements
Zinc
Copper
Selenium
Iron
Vitamins
Special Considerations
Other Additives/Considerations
Insulin
Refeeding Syndrome - DigitalRoberto Cavallaro, Cristina Colombo, editors.Summary: The book provides all the relevant information to understand the mental illness through psychopathology, global clinical manifestations and clinical patterns. It equips the reader with the basic knowledge to identify psychiatric conditions occurring alone or in the context of other medical illnesses, to distinguish health psychology and psychiatry, and to know what to do, how to do it, and how to communicate with the patient and to cooperate with the psychiatrist. The core chapters are dedicated to mental disorders diagnosed according to the DSM V, and are organized in sub-chapters with key feature boxes and schemes that will allow the global comprehension of the mental disorder and its clinical management. The work includes also a general chapter on psychopathology and one on psychopharmacology presenting the practical information about suggested doses, side effects, drug interactions and warnings for the main psychotropics. The final chapter deals with forensic and legal aspects. Fundamentals of Psychiatry for Health Care Professionals will appeal to a wide readership, from post graduate professionals who want to broaden their clinical knowledge of psychiatry to medical students and students of the health degree courses like Physiotherapy, Psychology, Nursing, or Dentistry.
Contents:
Preface. Introduction and assessment. - Psychopathology
Mood disorders
Psychotic disorders
Anxiety disorders
Somatic disorders
Obsessive-Compulsive Disorder
Trauma and stress related disorders and dissociative disorder
Personality disorders
Adult consequences of neurodevelopmental disorders
Eating disorders
Substance related disorders
Organic mental disorders
Psychopharmacology
Somatic treatments.-Management of Emergency psychiatry, including suicide
Psychiatric legislation and forensic psychiatry. - DigitalKakali Bhattacharya.Summary: "This book is the road map to proficiency and development in the field of qualitative research. Borrowing from a wealth of experience teaching introductory qualitative research courses, author Kakali Bhattacharya lays out a dynamic program for learning different paradigms of inquiry, empowering students to recognize the convergence of popular research methodologies as well as the nuances and complexities that set each of them apart."--Publisher.
Contents:
1. Unit 1 : meeting qualitative methods
2. Unit 2 : terrain and types of qualitative research
3. Unit 3 : conceptualizing qualitative research
4. Unit 4 : working with theoretical frameworks
5. Unit 5 : methodological approaches to qualitative inquiry
6. Unit 6 : data collection methods
7. Unit 7 : data analysis, interpretation, and re-presentation
8. Unit 8 : pulling it all together.Digital Access TandFonline 2017 - DigitalAgnes B. Fogo, author ; Arthur H. Cohen, Robert B. Colvin, J. Charles Jennette, Charles E. Alpers, co-authors.Summary: Fundamentals of Renal Pathology is a compact and up-to-date resource on the basics of renal pathology that will be of particular value to residents and fellows in training in renal pathology, general pathology, and nephrology, but will also serve as a handy reference for the more experienced. This second, revised and updated edition of the book offers an integrated approach based on contributions from established experts in the field. After considering normal renal anatomy and basic concepts and methods used in the assessment of renal biopsies, key diseases are discussed within the context of clinical presentations. The emphasis is on clinicopathological correlation and differential diagnosis. Topics discussed include glomerular diseases with nephrotic or nephritic syndrome presentations; systemic and vascular diseases affecting the kidney, including diseases affecting the renal transplant; tubulointerstitial diseases; and plasma cell dyscrasias and associated diseases. Well-chosen color illustrations and electron micrographs enhance and complement the text, and tables summarize the most up-to-date classifications and approaches for the various disease entities.
Contents:
Renal Anatomy and Basic Concepts and Methods in Renal Pathology
Membranous Nephropathy
Membranoproliferative Glomerulonephritis and C3 Glomerulopathy
Minimal Change Disease and Focal Segmental Glomerulosclerosis
Postinfectious Glomerulonephritis
IgA Nephropathy and IgA Vasculitis (Henoch-Schönlein Purpura)
Thin Basement Membranes and Alport Syndrome
Lupus Nephritis
Crescentic Glomerulonephritis and Vasculitis
Nephrosclerosis and Hypertension
Thrombotic Microangiopathies
Diabetic Nephropathy
Acute Interstitial Nephritis
Chronic Interstitial Nephritis
Acute Tubular Necrosis
Bence Jones Cast Nephropathy
Monoclonal Immunoglobulin Deposition Disease
Amyloidosis
Other Diseases with Organized Deposits
Allograft Rejection. - DigitalClyde A. Helms MD.Summary: "Trusted by thousands of radiology residents, students, and clinicians, the "pink book" continues to be the perfect first book for essential, easily accessible information in skeletal imaging. Fundamentals of Skeletal Radiology, 5th Edition, provides an authoritative introduction to x-rays, MR, and other skeletal imaging modalities, offering a quick, effective review of musculoskeletal imaging in a concise, easy-to-read style"--Publisher's description.
Contents:
1. Unnecessary examinations
2. Benign lytic lesions
3. Malignant tumors
4. "don't touch" lesions
5. Trauma
6. Arthritis
7. Metabolic bone disease
8. Miscellaneous conditions
9. Magnetic resonance imaging of the knee
10. Magnetic resonance imaging of the shoulder
11. Lumbar spine : disc disease and stenosis
12. Magnetic resonance imaging of the foot and ankle
13. Miscellaneous magnetic resonance imaging.
Differential diagnosesDigital Access ClinicalKey 2020 - Digital[edited by] Cynthia D. Mattice, Rita Brooks, Teofilo L. Lee-Chiong.Contents:
Section I. Overview of sleep medicine
section II. Anatomy and physiology
section III. Sleep disorders and disorders that affect sleep
section IV. Patient care and assessment
section V. Adult polysomnography
section VI. Interventions and therapeutics
section VII. Patient management
section VIII. Pediatrics
section IX. Sleep center management.Digital Access Ovid 2020 - Digitaledited by Shashi Gogia.Summary: Fundamentals of Telemedicine and Telehealth provides an overview on the use of information and communication technologies (ICTs) to solve health problems, especially for people living in remote and underserviced areas. With the advent of new technologies and improvement of internet connectivity, telehealth has become a new subject requiring a new understanding of IT devices and how to utilize them to fulfill health needs. The book discusses topics such as digitizing patient information, technology requirements, existing resources, planning for telehealth projects, and primary care and specialized applications. Additionally, it discusses the use of telemedicine for patient empowerment and telecare in remote locations. Authored by IMIA Telehealth working group, this book is a valuable source for graduate students, healthcare workers, researchers and clinicians interested in using telehealth as part of their practice or research. Presents components of healthcare that can be benefitted from remote access and when to rely on them Explains the current technologies and tools and how to put them to effective use in daily healthcare Provides legal provisions for telehealth implementation, discussing the risks of remote healthcare provision and cross border care.Digital Access ScienceDirect 2020
- DigitalGazi Huri, Mustafa Özkan, Kerem Bilsel, editors.Summary: This book comprehensively covers both basic and clinical aspects of the shoulder, from its anatomy and biomechanics, to the diagnosis and treatment of a broad range of shoulder disorders. Designed as a practical and richly illustrated reference guide, it provides the reader with the essentials needed to evaluate and treat shoulder injuries, including radiologic assessments, rehabilitative techniques and surgical procedures (both open and arthroscopic). It includes extensive coverage of the anatomy and pathology, while clinical topics covered include fractures around the shoulder joint, sport injuries and arthroplasty. Written by an international team of experts, who share tips, pearls and pitfalls, as well as best practices from their own experience, the book will be of interest to orthopedic surgeons, physical therapists, rehabilitation specialists and biomechanists alike.
Contents:
Part I: Shoulder basic science & principles
1. Shoulder embryology and anatomy
2. Molecular biology and Genetics in Shoulder pathologies
3. Animal models for research on shoulder pathologies
4. Shoulder Kinematics and Biomechanics
5. Pathomechanics and mathematics of anterior shoulder instability
6. Pathomechanics in CTA and rationale of RSA
7. Rationale of tendon to bone healing
Part II: Diagnosis of shoulder conditions
8. Physical examination for glenohumeral joint pathologies
9. Physical examination for subacromial and acromioclavicular pathologies
10. Radiological assessment of the shoulder
Part III: Shoulder pathologic conditions
11. Shoulder cartilage and osteoarthritis
12. Inflammatory, metabolic and neuromuscular pathologies in shoulder joint
13. Nerve entrapment around shoulder joint
14. Fractures around shoulder
Part IV: Shoulder surgety and complications
15. Positioning, anaesthesia and analgesia in shoulder surgery
16. Surgical exposures
17. Basic arthroscopy portals of shoulder
18. Thromboembolism and bleeding control in shoulder surgery
19. Periprosthetic infection in shoulder surgery
Part V: (Bio)technological applications in shoulder treatment
20. Implants and biomaterials
21. Tissue Engineering and graft options
22. 3D printing in shoulder surgery
23. Digitized Shoulder. - DigitalJohn W. Ridley.Summary: This volume provides the essential theory as well as practice for the study of urine samples and body fluids other than urine. It is a concise compendium of information of a practical nature while additionally serving as a clinical resource leading to an understanding of clinical conditions for patients whose test specimens indicate the presence of a pathological condition. Selective laboratory procedures inform the investigator not only of how specimens are processed, but also the rationale for performing specific examinations. Parameters by which testing personnel may measure or evaluate the validity, accuracy and clinical implications of test results for clinical importance providing optimum and useful information are provided.
Contents:
Chapter 1: Introduction to the Study of Body Fluids
Chapter 2: Quality Assurance and Laboratory Regulation
Chapter 3: Safety Practices in Testing Areas
Chapter 4: Metabolic Origins of Urine and Other Body Fluids
Chapter 5: Microscopic Components Common to Body Fluids
Chapter 6: Specimen Collection of Body Fluids
Chapter 7: Diseases of the Urinary System
Chapter 8: Components of the Evaluation of Urine
Chapter 9: Microscopic Examination
Chapter 10: Procedure for Performing Complete Urinalysis
Chapter 11: Cerebrospinal Analysis
Chapter 12: Semen Evaluation
Chapter 13: Serous Fluids Analysis
Chapter 14: Synovial Fluid Evaluation
Chapter 15: Fecal Analysis
Chapter 16: Miscellaneous Related Laboratory Analyses
Chapter 17: Microscope Use and Care. - DigitalWanda M. Haschek, Brad Bolon, Colin G. Rousseaux, Matthew A. Wallig.Digital Access ScienceDirect 2017
- DigitalMargarethe Geiger, editor.Summary: This well-structured textbook offers essential knowledge on the vascular system. The reader will learn the properties, basic cellular mechanisms and development of the different parts of the vascular system (including the heart), gain knowledge on vascular and related diseases, and will be made familiar with common and most current methods and techniques applied to analyze the vascular system in patients, in animal models, and ex vivo. This book is based on a PhD Course for students from various bioscientific backgrounds given at the Medical University of Vienna, and it will be a valuable resource for Master's Students in vascular biology and biomedicine in general and a helpful tool for young researchers world-wide wishing to gain or refresh their knowledge in this field.
Contents:
1. Morphological and Functional Characteristics of Blood and Lymphatic Vessels
2. The Heart: The Engine in the Center of the Vascular System
3. Regulation of Tissue Perfusion and Exchange of Solutes, Macromolecules, and Water between Blood Vessels and the Interstitial Space
4. Endothelial Cells: Function and Dysfunction
5. Vascular Smooth muscle cells: Regulation of Vasoconstriction and Vasodilation
6. Embryonic Development of the Cardiovascular System
7. Cellular and Molecular Mechanisms of Vasculogenesis, Angiogenesis, and Lymphangiogenesis
8. Mechanisms of Hemostasis: Contribution of Platelets, Coagulation Factors, and the Vessel Wall
9. Biologically active lipids in Vascular Biology
10. Atherosclerosis
11. Venous Thromboembolism
12. Genetics of Vascular Diseases
13. Animal Models in Cardio-Vascular Biology
14. Endothelial Cell Isolation and Manipulation
15. In vitro Assays Used to Analyse Vascular Cell Functions
16. The Porcine Coronary Artery Ring Myograph System
17. Proteomics in Vascular Biology. - DigitalRalph W. Aye, John G. Hunter, editors.
- Digital[edited by] Noemi Lois, MD, PhD, FRCS(Ed), FRCOphth, Clinical Professor of Ophthalmology, Centre for Experimental Medicine, Institute for Clinical Sciences, Queen's University belfast, Honorary Consultant Ophthalmologist, Belfast Health and Social Care Trust, Northern Ireland, United Kingdom, John V. Forrester, MB, ChB, FRCS(E), MD(Hons), FRCS(G), FRCOphth, FRCP(G)(Hon), FMEDSci, FRSE, FSBiol, FARVO, FRANzCO, Section on Immunology and Infection, Division of Applied Medicine, School of Medicine and Dentistry, The Institute of Medical Scineces, Fosterhill, University of Aberdeen, Scotland, United Kingdom, Ocular Immunology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia, Centre for Experimental Immunology, Lions Eye Institute, Newlands, Western Australia, Australia.Contents:
Section I. Basic Science
Chapter 1. Lipofuscin of the retinal pigment epithelium
Chapter 2. Lipofuscin: the origin of the autofluorescence signal
Chapter 3. Lipofuscin and autofluorescence in experimental animal models
Chapter 4. Imaging techniques of fundus autofluorescence
Chapter 5. Near-infrared fundus autofluorescence
Chapter 6. Interpreting fundus autofluorescence
Chapter 7. Quantifying fundus autofluorescence
Section II. Clinical Science
Chapter 8. The normal distribution of fundus autofluorescence
Chapter 9. Fundus autofluorescence in age-related macular disease
Chapter 10. Fundus autofluorescence in inherited retinal dystrophies
Chapter 11. Fundus autofluorescence in diabetic retinopathy
Chapter 12. Fundus autofluorescence in retinal artery occlusion
Chapter 13. Fundus autofluorescence in retinal vein occlusion
Chapter 14. Fundus autofluorescence in pathological myopia
Chapter 15. Fundus autofluorescence in macular telangiectasia Type 2
Chapter 16. Fundus autofluorescence in cystoid macular edema
Chapter 17. Fundus autofluorescence in posterior uveitis
Chapter 18. Central serous chorioretinopathy
Chapter 19. Pseudoxanthoma elasticum
Chapter 20. Fundus autofluorescence in vitreoretinal diseases
Chapter 21. Fundus autofluorescence in intraocular tumors
Chapter 22. Fundus autofluorescence in toxic retinopathies.Digital Access Ovid 2016 - Digital/PrintChristine Imbert, editor.Contents:
Aspergillus biofilms in human disease
Candida albicans in multispecies oral communities: a keystone commensal?
The extracellular matrix of fungal biofilms
Fungal biofilms: update on resistance
Fungi, water supply and biofilms
Diagnostic of fungal infections related to biofilms
Disinfectants to fight oral Candida biofilms
Updates on therapeutic strategies against Candida (and Aspergillus) biofilm related infections
Natural sources as innovative solutions against fungal biofilms
Index.Digital Access Springer 2016 - DigitalAbd El-Latif Hesham, Ram Sanmukh Upadhyay, Gauri Dutt Sharma, Chakravarthula Manoharachary, Vijai Kumar Gupta, editors.Summary: Fungi are eukaryotic microorganisms that include both unicellular and multicellular species. They have a worldwide distribution and a wide range of applications in diverse sectors, from environmental, food and medicine to biotechnological innovations. Fungal biochemical genetics involves the study of the relationships between genome, proteome and metabolome, and the underlying molecular processes in both native and bioengineered fungi. This book provides a valuable resource on the challenges and potential of fungal biotechnology and related bioengineering and functional diversity for various industrial applications in the food, environmental, bioenergy and biorefining, and the biopharma sectors. In comparison to previous and related publications in the area of applied myco-biotech-engineering, this book bridges a knowledge gap in the areas related to prospects and investment as well as intellectual and technical issues. This book also provides information on recent commercial and economic interests in the area by juxtaposing the developments achieved in recent worldwide research and its many challenges.
Contents:
Foreword
Fungal Epigenetic Engineering
Yeast engineering for new antifungal compounds: a contextualized overview
G protein-coupled receptors in fungi
Prompt and convenient preparation of oral vaccines using yeast cell surface display
Trichoderma a factory of multipurpose enzymes
Advances genomic approaches for mining fungal genes for biofuels
Genetically modified fungi for second generation bioethanol production
Fungal Bioengineering in Biodiesel Production
Bioengineering fungi and yeast for the production of enzymes, metabolites and value-added compounds
Fungal production of prebiotics
Fermentative production of secondary metabolites from Bioengineered Fungi and their applications
Recent progress on Trichoderma secondary metabolites
Fungal genes encoding enzymes that are used in cheese production and fermentation industries
Unravelling the potentials of endophytes and its applications
Fungal genes and gene products involved in wastewater treatments
DNA Barcode for Species Identification in Fungi
Current progress on endophytic microbial dynamics on Dendrobium plants.-Understanding its role bioengineered Trichoderma in managing soil-borne plant diseases and its other benefits
Beyond classical biocontrol: new perspectives on Trichoderma
Systemic acquired resistance (SAR) and Induced systemic resistance (ISR) mechanism of Trichoderma against pathogens.Digital Access Springer 2020 - PrintJean-Paul Latgé, editor.Summary: This book illustrates, that the fungal cell wall is critical for the biology and ecology of all fungi and especially for human fungal pathogens. Readers will learn, that the composition of the fungal cell wall is a unique structure, which cannot be found in the human host. Consequently, the chapters outline, how the immune systems of both animals and humans have evolved to recognize conserved and unique elements of the fungal cell wall. As an application example, the authors also show, that the three-dimensional structures of the cell wall are excellent targets for the development of antifungal agents and chemotherapeutic strategies. With the combination of biological findings and medical outlooks, this volume is a fascinating read for scientists, clinicians and biomedical students.
Contents:
Synthesis of mimicks
Melanin
Rodlets and cell wall surface proteins
Alpha 1,3 and Beta 1,3 glucans and remodelling
Chitin
Cell wall PAMPs and PRRs in mammalians
Extracellular polysaccharides and biofilms
Cell wall drugs and resistance mechanisms
GPI proteins and cell wall
Cell wall and morphogenesis
Carbohydrate active enzymes in fungi B
Glucanases and chitinases
Respiration and cell wall synthesis
Cell wall and environment. . - DigitalXu Fang, Yinbo Qu, editors.Summary: The book provides an overview of the current knowledge on cellulolytic enzymes and their applications. It summarizes the mechanisms of synthesis and hydrolysis of cellulolytic enzymes, industrial fungal strains, genetic engineering of fungal strains and application of cellulolytic enzymes. This book will be a useful reference for researchers and bioengineering experts engaged in lignocelluloses biodegradation, biomass utilization, enzyme production and fungal molecular biology.
Contents:
Intro; Preface; Contents; Contributors;
Chapter 1: Pretreatment Process and Its Synergistic Effects on Enzymatic Digestion of Lignocellulosic Material; 1 Introduction; 2 Lignocellulose Compositions; 3 Pretreatment of Lignocellulosic Materials; 4 Physical Pretreatment; 4.1 Mechanical Pretreatment; 4.2 Pyrolysis; 4.3 Irradiation; 5 Chemical Pretreatment; 5.1 Ozonolysis; 5.2 Acid Pretreatment; 5.3 Alkaline Pretreatment; 5.4 Ionic Liquid Pretreatment; 5.5 Organosolv Pretreatment; 6 Physical-Chemical Pretreatment; 6.1 Steam Explosion; 6.2 Liquid Hot Water Pretreatment; 6.3 Oxidative Pretreatment. 6 Metabolic Engineering of Filamentous Fungi Using CRISPR-Cas9-Based Genome Editing System7 Conclusion and Future Prospects; References;
Chapter 3: Lignocellulase Formation, Regulation, and Secretion Mechanisms in Hypocrea jecorina (Trichoderma reesei) and Other Filamentous Fungi; 1 Introduction; 2 Transcriptional Mechanisms that Regulate Cellulase and Hemicellulase Gene Expression; 2.1 Transcriptional Factors; 2.2 Other Regulatory Factors; 3 Chromatin Remodeling; 4 Transcriptional Regulation of Cellulase and Hemicellulase in H. jecorina by External Signals; 5 Prospects; References. 6.4 SPORL Pretreatment6.5 Ammonia Fiber Explosion (AFEX) and Ammonia Recycle Percolation(ARP); 6.6 CO2 Explosion; 7 Biological Pretreatment; 8 Summary of Biomass Pretreatment Methods; References;
Chapter 2: Metabolic Engineering of Fungal Strains for Efficient Production of Cellulolytic Enzymes; 1 Introduction; 2 Selective Markers for Genetic Engineering of Filamentous Fungi; 3 Promoter Engineering to Improve Cellulase Production; 4 Engineering of Transcription Regulators to Improve Cellulase Production; 5 Improvement of Cellulase Production by Morphology Engineering.
Chapter 4: Development of Highly Efficient, Low-Cost Lignocellulolytic Enzyme Systems in a Penicillium: From Strain Screening to Systems Biology1 Introduction; 2 Genome and Transcriptome Analyses of P. oxalicum Wild-Type Strain 114-2 and Mutant JU-A10-T; 2.1 Global Comparison of Genomes of 114-2 and JU-A10-T; 2.2 Comparative Transcriptome Analysis of 114-2 and JU-A10-T; 3 Secretome Analysis of P. oxalicum Wild-Type Strain 114-2 and Mutant JU-A10-T; 4 Improving Lignocellulolytic Enzyme Production by Redesigning the Regulatory Pathway; 4.1 Transcription Factors. - Digital/PrintMarcio Rodrigues, Guilhem Janbon, editors.Summary: This book provides an in-depth overview on the manifold functions of fungal extracellular vesicles (EV) which span from cell-to-cell communication, pathogenicity and stimulation of host's immunity to export of hundreds of biomolecules. The book summarizes the present knowledge on the impact of extracellular vesicles on fungal biology. Extracellular vesicles participate in fundamental biological processes in all living cells but only during the last 15 years the production and functions of EVs were identified and studied in fungal species too. Up to date more than 50 independent studies have shown that extracellular vesicles are produced by at least 20 fungal species. The book addresses researchers and advanced students in Microbiology, Mycology and Biotechnology.
Contents:
Preface
Foreword
Chapter 1. Biogenesis of Fungal Extracellular Vesicle: what do we know?
Chapter 2. Lessons learned from studying Histoplasma capsulatum extracellular vesicles
Chapter 3. Current Status on Extracellular Vesicles from the Dimorphic Pathogenic Species of Paracoccidioide
Chapter 4. Extracellular vesicles from Sporothrix yeast cells
Chapter 5. Filamentous Fungi Extracellular Vesicles
Chapter 6.Extracellular vesicles and the propagation of yeast prions
Chapter 7. Contributions of Extracellular Vesicles to Fungal Biofilm Pathogenesis
Chapter 8.Fungal extracellular vesicles in interkingdom communication
Chapter 9. Interactions of extracellular vesicles from pathogenic fungi with innate leukocytes
Chapter 10. Fungal extracellular vesicles as a potential strategy for vaccine development
Chapter 11. Current microscopy strategies to image fungal vesicles: from the intracellular trafficking and secretion to the inner structure of isolated vesicles
Chapter 12. Proteomic characterization of EVs in non-pathogenic yeast cells. - DigitalMehmet Turgut, Sundaram Challa, Ali Akhaddar, editors.Summary: This book provides comprehensive information on fungal infections of the central nervous system (CNS). Fungal infections are still a major public health challenge for most of the developing world and even for developed countries due to the rising numbers of immune compromised patients, refugee movements, and international travel. Although fungal infections involving the CNS are not particularly common, when they do occur, the results can be devastating in spite of recent advances and currently available therapies. Further, over the past several years, the incidence of these infections has seen a steep rise among immunodeficient patients. In this context, aggressive surgery remains the mainstay of management, but conservative antifungal drug treatment complemented by aggressive surgical debridement may be necessary. Yet the optimal management approach to fungal infections of the CNS remains controversial, owing to the limited individual experience and the variable clinical course of the conditions. Addressing that problem, this comprehensive book offers the ideal resource for neurosurgeons, neurologists and other specialists working with infectious diseases.
Contents:
PREFACE
INTRODUCTION
SECTION I: GENERAL CONSIDERATIONS
Historical aspects of fungal infections
Epidemiology of fungal infections
Morphological classification of fungal infections (yeasts, molds, dimorphic)
Pathogenesis of fungal infections
Predisposing factors
Histopathology
Molecular genetics and genomics of fungal infections
SECTION II: FUNGAL PATHOGENS: PATHOGENESIS, PATHOLOGY AND DIAGNOSIS
Chapter 8: Aspergillosis
Candidiasis
Mucormycosis
Histoplasmosis and coccidioidomycosis
Cryptococcosis
Blastomycosis and phaeohyphomycosis
Onychomycosis
epeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;">Emmonsiosis
Cladophialophora bantiana
Cladosporidium, Fusarium spp, Bipolaris hawaiiensis, Schizophyllum commune, Mycoplasma hominis, Scedosporium apiospermum
SECTION III: CLINICAL SYNDROMES OF FUNGAL INFECTIONS INVOLVING CENTRAL NERVOUS SYSTEM AND ITS COVERINGS
Meningitis and meningo-encephalitis
Raised intracranial pressure
Hydrocephalus
Intracranial space occupying lesions
Skull-base syndromes
Orbito-rhino-cerebral syndrome
Cavernous sinus syndrome
Intracranial fungal aneurysms
Acute ischemic or hemorrhagic stroke syndromes
Spinal syndromes
SECTION III: RADIOLOGICAL FINDINGS OF FUNGAL INFECTIONS INVOLVING CENTRAL NERVOUS SYSTEM AND ITS COVERINGS
Magnetic resonance imaging
Positron emission tomography-computed tomography
Imaging findings of fungal infections of the cranial and peripheral nerves
Imaging findings of fungal infections of sinuses extending into brain
Imaging findings of fungal infections of spine and spinal cord
SECTION IV: THERAPY OF FUNGAL INFECTIONS INVOLVING CENTRAL NERVOUS SYSTEM AND ITS COVERINGS
Antifungals: from genomics to resistance and the development of novel agents
Surgical therapy
Prognosis of fungal infections involving the central nervous system and its coverings
SECTION VI: FURTHER INSIGHTS INTO FUNGAL INFECTIONS
In vitro and animal models of fungal infections oReal-time PCR: advanced technologies and applications
Next-generation sequencing: current technologies and applications
Current innovations and future trends
CONCLUSIONS. - DigitalRam Prasad, Vivek Kumar, Manoj Kumar, Shanquan Wang, editors.Summary: Fungal nanobionics has great prospects for developing new products with industrial, agriculture, medicine and consumer applications in a wide range of sectors. The fields of chemical engineering, agri-food, biochemical, pharmaceuticals, diagnostics and medical device development all employ fungal products, with fungal nanomaterials currently used in a wide range of applications, ranging from drug development to food industry and agricultural sector. The fungal agents emerge as an environmentally friendly, clean, non-toxic agent for the biogenic metal nanoparticles and employs both intracellular and extracellular methods. The simplicity of scaling up and downstream processing and the presence of fungal mycelia affording an increased surface area provide key advantages. In addition, the larger spectrum of synthesized nanoparticle morphologies and the substantially faster biosynthesis rate in cell-free filtrate (due to the higher amount of proteins secreted in fungi) make this a particularly enticing route. Understanding the diversity of fungi in assorted ecosystems, as well as their interactions with other microorganisms, animals and plants, is essential to underpin real and innovative technological developments and the applications of metal nanoparticles in many disciplines including agriculture, catalysis, and biomedical biosensors. Importantly, biogenic fungal nanoparticles show significant synergistic characteristics when combined with antibiotics and fungicides to offer substantially greater resistance to microbial growth and applications in nanomedicine ranging from topical ointments and bandages for wound healing to coated stents.
Contents:
Nanobiocomposites: Synthesis and Environmental Applications
Medical and Cosmetic Applications of Fungal Nanotechnology: Production, Characterization and Bioactivity
Fungal Nanoparticles: A Novel Tool for a Green Biotechnology?
Application of Nanotechnology in Mycoremediation: Current Status and Future Prospects
Fungal Nanotechnology: A New Approach Toward Efficient Biotechnology Application
Advances in Biomedical Application of Chitosan and its Functionalized Nano-derivatives
Biosynthesis of Metal Nanoparticles via Fungal Dead Biomass in Industrial Bioremediation Process
Nanofabrication of Myconanoparticles: A Future Prospect
In vitro Secondary Metabolite Production Through Fungal Elicitation: An Approach for Sustainability
Metal and Metal Oxide Mycogenic Nanoparticles and Their Application as Antimicrobial and Antibiofilm Agents
Applications of Fungal Nanobiotechnology in Drug Development
Mycosynthesized Nanoparticles: Role in Food Processing Industries. - PrintMarcio L. Rodrigues, editor.Summary: This volume offers an overview of the various aspects involved in the ability of fungi to damage host cells, and discusses cutting-edge approaches to the study of fungal pathogenesis. The first chapter illustrate the key roles of glycans and pigments, the most abundant surface components in fungal cells, in their interactions with host cells. The connections between cellular physiology and fungal pathogenesis are then discussed in the following chapters. Physiology-related processes affecting pathogenesis include fungal secretion, morphological transitions, and response to light. In turn, the book illustrates mechanisms of damage to host cells using the Histoplasma capsulatum model of infection, and reviews the use of transcriptomic approaches to understand the mechanisms of interaction between fungal cells and host tissues. After a discussion of the immunological mechanisms underlying host susceptibility to fungal infections, the books closing contribution reviews the mechanisms of interaction between fungi and other microbes, and the impact of this association on fungal pathogenesis. Given its scope, the book will appeal to scientists in the fields of mycology, microbiology, infectious diseases, biology and medicine.
Contents:
Candida morphology and pathogenesis
Fungal biofilms
Immunoactive fungal vesicles
Candida parapsilosis pathogenesis
Fungal circadian clocks and pathogenesis
Cryptococcal pathogenesis
Nucleic acid export in fungi
Immunity to fungal infections
Fungal systems biology. - DigitalMarcio L. Rodrigues, editor.Summary: This volume offers an overview of the various aspects involved in the ability of fungi to damage host cells, and discusses cutting-edge approaches to the study of fungal pathogenesis. The first chapter illustrate the key roles of glycans and pigments, the most abundant surface components in fungal cells, in their interactions with host cells. The connections between cellular physiology and fungal pathogenesis are then discussed in the following chapters. Physiology-related processes affecting pathogenesis include fungal secretion, morphological transitions, and response to light. In turn, the book illustrates mechanisms of damage to host cells using the Histoplasma capsulatum model of infection, and reviews the use of transcriptomic approaches to understand the mechanisms of interaction between fungal cells and host tissues. After a discussion of the immunological mechanisms underlying host susceptibility to fungal infections, the books closing contribution reviews the mechanisms of interaction between fungi and other microbes, and the impact of this association on fungal pathogenesis. Given its scope, the book will appeal to scientists in the fields of mycology, microbiology, infectious diseases, biology and medicine.
Contents:
Candida morphology and pathogenesis
Fungal biofilms
Immunoactive fungal vesicles
Candida parapsilosis pathogenesis
Fungal circadian clocks and pathogenesis
Cryptococcal pathogenesis
Nucleic acid export in fungi
Immunity to fungal infections
Fungal systems biology. - DigitalKalyani Dhusia, Kalpana Raja, Pramod Ramteke, editors.Summary: In the past few decades, it has been realized through research that fungal siderophores epitomize the uptake of iron as well as other essential elements like zinc, magnesium, copper, nickel and arsenic. Understanding the chemical structures of different fungal siderophores and the membrane receptors involved in uptake of mineral ions has opened new areas for research. In this edited volume, recent research is presented on fungal siderophores in one comprehensive volume to provide researchers a strong base for future research. Siderophores are the low molecular weight, high affinity iron-chelating compounds produced by bacteria and fungi. They are responsible for transporting iron across the cell membrane. Fungi produce a range of hydroxamate siderophores involved in the uptake of essential elements in almost all microorganisms and plants. In recent years, siderophores have been used in molecular imaging applications to visualize and understand cellular functions, which thus provide an opportunity to identify new drug targets. Therefore, knowledge of fungal siderophores has become vital in current research. Siderophores have received much attention in recent years because of their potential roles and applications in various research areas. Their significance in these applications is because siderophores have the ability to bind a variety of metals in addition to iron, and they have a wide range of chemical structures and specific properties. For instance, siderophores function as biocontrols, biosensors, and bioremediation and chelation agents, in addition to their important role in weathering soil minerals and enhancing plant growth. This book focuses on siderophores with the following significant points. It discusses leading, state-of-the-art research in all possible areas on fungal siderophores. The contributors are well-known and recognized authorities in the field of fungal siderophores. It discusses a projection of practical applications of fungal siderophores in various domains. This is the first book exclusively on fungal siderophores. In this comprehensive, edited volume, we show leading research on fungal siderophores and provide the most recent knowledge of researchers' work on siderophores. This book presents in-depth knowledge on siderophores to researchers working in areas of health sciences, microbiology, plant sciences, biotechnology, and bioinformatics.
Contents:
Preface
1. Fungal siderophores: origin, structure and functions
2. Fungal siderophore biosynthesis (NRP dependent)
3. Fungal siderophore biosynthesis (NRP independent)
4. Fungal siderophores and chelation of iron
5. Fungal siderophores and non-iron metal ion complex formation
6. Role of fungal siderophores in control of fungal infections
7. Fungal siderophores and control of bacterial and viral pathogens
8. Strategies involving siderophore mediated anti-pathogenicity
9. Fungal siderophores in treatment of human diseases
10. Applications of fungal siderophores in remediation of heavy metal contaminated soil
11. Omics implications in fungal siderophores
12. Exploring avenues of current research to practical implications
Index
Bibliography. - Digitaledited by Kevin Kavanagh.Contents:
Introduction to fungal physiology / Graeme M. Walker and Nia A. White
Fungal genetics / Malcolm Whiteway and Catherine Bachewich
Fungal genomics / David Fitzpatrick
Fungal genetics : a post-genomic perspective / Brendan Curran and Virginia Bugeja
Fungal proteomics / Sean Doyle and Rebecca Owens
Fungi as food / Johan Baars
Pharmaceutical and chemical commodities from fungi / Karina A. Horgan and Richard A. Murphy
Biotechnological use of fungal enzymes / Shauna M. McKelvey and Richard A. Murphy
Biotechnological exploitation of heterologous protein production in fungi / Brendan Curran and Virginia Bugeja
Fungal infections of humans / Derek J. Sullivan, Gary P. Moran, and David C. Coleman
Immunity to human fungal infections / Mawieh Hamad, Mohammad G. Mohammad, and Khaled H. Abu-Elteen
Antifungal agents for use in human therapy / Khaled H. Abu-Elteen and Mawieh Hamad
Fungi in the environment / Richard O'Hanlon
Fungal pathogens of plants / Fiona Doohan and Binbin Zhou.Digital Access Wiley 2018 - DigitalPraveen Gehlot, Joginder Singh, editors.Summary: This book illustrates the multiple roles of fungi in everyday life. Fungi are the large group of organisms with tremendous diversity and economic importance. Their ability to produce commercially efficient useful products makes them the vulnerable sustainable tool for the future generation. This book describes a systems approach and provides a means to share the latest developments and advances about the benefits of fungi including their wide application, traditional uses, modern practices, along with designing of strategies to harness their potential. The chapters are organized with data, providing information related to different sustainable aspects of fungi in agriculture, its cultivation and conservation strategies, industrial and environmental utilization, advanced bioconversion technologies and modern biotechnological interventions. Updated information and current opinion related to its application for sustainable agriculture, environment, and industries as futuristic tools have been presented and discussed in different chapters. The book also elucidates a comprehensive yet a representative description of the challenges associated with the sustained application of fungi to achieve the goals of sustainability.
Contents:
Module 1_ Sustainable Cultivation and Conservation Strategies of Fungi.- Chapter 1. Cultivation, conservation and medicinal significance of macro-fungi.- Chapter 2. Fungi as biocontrol agent: an alternate to chemicals.- Chapter 3. Role of Fungi in various Fields for sustainable development.- Chapter 4. The biological promises of endophytic Muscodor species.- Chapter 5. Slime Moulds: The Tiny Charmers.- Module 2_ Sustainable Aspects of Fungi in Agriculture.- Chapter 6. Fungal Endophytes: Role in Sustainable Agriculture.- Chapter 7. Fungal endophytes and their Secondary metabolites
Role in sustainable agriculture.- Chapter 8. Agricultural important microorganism- Sustainability from rhizosphere to bioformulation as weapon for biological control.- Chapter 9. Mycopesticides: Fungal based pesticides for sustainable agriculture.- Chapter 10. Multifactorial role of Arbuscular Mycorrhizae in Agroecosystem.- Chapter 11. - DigitalXiaofeng Dai, Minaxi Sharma, Jieyin Chen, editors.Summary: This book presents research on the challenges and potential of fungal contribution in agriculture for food substantiality. Research on fungi plays an essential role in the improvement of biotechnologies which lead global sustainable food production. Use of fungal processes and products can bring increased sustainability through more efficient use of natural resources. Fungal inoculum, introduced into soil together with seed, can promote more robust plant growth through increasing plant uptake of nutrients and water, with plant robustness being of central importance in maintaining crop yields. Fungi are one of natures best candidates for the discovery of food ingredients, new drugs and antimicrobials. As fungi and their related biomolecules are increasingly characterized, they have turned into a subject of expanding significance. The metabolic versatility makes fungi interesting objects for a range of economically important food biotechnology and related applications. The potential of fungi for a more sustainable world must be realized to address global challenges of climate change, higher demands on natural resources.
Contents:
Intro
Foreword
Preface
Contents
About the Editors
Chapter 1: Fungal Byproducts in Food Technology
1.1 Introduction
1.2 Use of Fungi in Food Biotechnology
1.3 Fungal Byproducts
1.3.1 Proteins from Filamentous Fungi Biomass
1.3.2 Byproducts from Fungal Fermentation
1.3.3 Fungal Chitosan
1.3.4 Other Fungal Byproducts
1.4 Unenviable Fungal Byproducts
1.5 Conclusion and Future Prospects
References
Chapter 2: Fungal Production of Dietary Fibers
2.1 Definition
2.2 Introduction
2.3 Production 2.3.1 Preparation of Fungus (Mushroom) as Dietary Fiber
2.3.2 Commercial Mushroom Production in the Asian Tradition
2.4 Importance
2.5 Conclusion
2.6 Future Prospects
References
Chapter 3: GRAS Fungi: A New Horizon in Safer Food Product
3.1 Introduction
3.2 History of GRAS
3.3 Fungi in All Quarters
3.4 Fungi in Food
3.4.1 Directly Consumed as Food
3.4.2 Secondary Metabolites
3.4.3 Alcoholic Beverages
3.5 Applications
3.5.1 Exploited as Nutraceuticals
3.5.2 Antioxidant Activity
3.5.3 Increased Shelf-Life of Vegetables and Fruits 3.5.4 Flavouring Agent
3.5.5 Colouring Agent
3.6 List of GRAS-Certified Fungi and Their Products
3.7 Concern of GRAS Ingredients
References
Chapter 4: Fungi in Food Bioprocessing
4.1 Introduction
4.2 Useful Fungi
4.3 Fermentation Processes
4.3.1 Natural Fermentation
4.3.2 Starter-Mediated Single-Stage Fermentation
4.3.3 Multiple-Stage Fermentation
4.4 Fermented Products: Manufacturing and Fungal Species Involved
4.4.1 Bread
4.4.1.1 Baker's Yeast
4.4.1.2 Baking Technology
Bulk Fermentation Process
The Mechanical Dough Development Method 4.4.2 Sufu (Furu)
4.4.2.1 Naturally Fermented Sufu
4.4.2.2 Enzymatically Produced Sufu
4.4.2.3 Bacterial Fermented Sufu
4.4.2.4 Fungal Fermented Sufu
4.4.2.5 Grey Sufu
4.4.2.6 White Sufu
4.4.2.7 Red Sufu
4.4.2.8 Other Types
4.4.2.9 Mycology of Sufu
4.4.2.10 Manufacturing Process
Preparation of Tofu
Preparation of Pehtze (Pizi)
Salting
Ripening
4.4.3 Red Kojic Rice
4.4.3.1 Fungi Involved
4.4.3.2 Manufacturing Process
4.4.4 Soy Sauce
4.4.4.1 Fungal Species Involved
4.4.4.2 Manufacturing Process
4.4.5 Tempe
4.4.5.1 Mycology of Tempe 4.4.5.2 Manufacturing Process
4.4.6 Wine
4.4.6.1 Mycology of Wine Fermentation
4.4.6.2 Manufacturing Process
4.5 Conclusion
References
Chapter 5: Fungal Productions of Biological Active Proteins
5.1 Fungi as Source of Bioactive Proteins
5.2 Inhibition of Angiotensin-Converting Enzyme by Mushroom
5.3 Antioxidant
5.4 Antifungal
5.5 Ribosome-Inactivating Proteins
5.6 Antibacterial
5.7 Conclusions
References
Chapter 6: Fungal Pectinases: Production and Applications in Food Industries
6.1 Introduction
6.2 Biochemical Characteristics of Pectinases - Digitaleditor, Luiz Henrique Rosa.Summary: This book focuses on the fungi found in one of the most pristine regions on Earth: Antarctica. It discusses the fungal occurrence in all substrates of the region, including soil, seawater, lake and marine sediments, rocks, ice, and snow. It also addresses the impact of climate changes on these organisms, the genomic techniques developed to study them, and how a number of compounds, such as antibiotics and enzymes, produced by the Antarctic fungi can be used in medicine, agriculture and the chemical industry.
Contents:
Preface
Fungi in Antarctica: Diversity, ecology, effects of climate change, and bioprospection for bioactive compounds
Uncultivated Fungi from Antarctica
Fungi present in soils of Antarctica
Diversity and ecology of fungal assemblages present in lakes of Antarctica
Rock-inhabiting fungi in Antarctica: new frontiers of the edge of life
Fungi in snow and glacial ice of Antarctica
Antarctic permafrost: an unexplored fungal microhabitat at the edge of life
Fungi associated with plants and lichens of Antarctica
Fungus-invertebrate interactions in Antarctica
Sub-Antarctic and Antarctic marine ecosystems: an unexplored ecosystem of fungal diversity
The use of psychrophilic Antarctic yeast in the biological control of post-harvest diseases of fruits stored at low temperatures
Bioactive compounds produced by Antarctic filamentous fungi
Antarctic yeasts as a source of enzymes for biotechnological applications
Antarctic fungi as producers of pigments
Genomics of Antarctic fungi: A new frontier
Index. - Digitaleditors, Valentin Fuster, Jagat Narula, Prashant Vaishnava, Martin B. Leon, David J. Callans, John S. Rumsfeld, Athena Poppas.Summary: "World-famous for its authority and clinical relevance, Fuster and Hursts The Heart is cardiologys longest continuously published reference book. Written to meet the ever-changing needs of cardiologists, fellows, and interns, this trusted classic offers a solid foundation in cardiovascular medicine and complete coverage of all major cardiovascular topics. This fifteenth edition presents a greater focus on the practicalities of patient care. Additionally, the content is ordered in a more methodical pattern, from mechanism to management. Reflecting the latest technical, therapeutic, and clinical advances, Fuster and Hursts The Heart provides invaluable concise summaries of major new trials and guidelines."--Amazon
Contents:
1. The Global Burden of Cardiovascular Diseases / Catherine P. Benziger, Andrew E. Moran, Gregory A. Roth, George A. Mensah
2. Clinical Cardiovascular Examination / William R. Miranda, Rick A. Nishimura
3. Cardiovascular Imaging / Thomas H. Marwick, Jagat Narula
4. Genomics and Epigenomics of Heart Diseases / June-Wha Rhee, Joseph C. Wu
5. Epidemiology, Pathophysiology, and Treatment of Hypertension / Michael E. Hall, John E. Hall, Paul K. Whelton
6. Cardiometabolic Disease: Insulin Resistance, Obesity, and the Metabolic Syndrome / W. Timothy Garvey, Jeffrey I. Mechanick
7. Diabetes and Cardiovascular Disease / Jeffrey I. Mechanick, Michael E. Farkouh
8. Tobacco-Related Cardiovascular Disease / Nancy A. Rigotti, Sara Kalkhoran, Neal L. Benowitz
9. Air Pollution and Cardiovascular Disease / Michael B. Hadley, Sanjay Rajagopalan
10. Hypercholesterolemia, Hyperlipoproteinemia(a), Hypertriglyceridemia, and Low HDL / Robert S. Rosenson, Marlys L. Koschinsky, Børge G. Nordestgaard, Robert A. Hegele
11. Psychological Factors in Cardiovascular Health and Disease / Darwin R. Labarthe, Rosalba Hernandez 12. Sedentary Lifestyle and Role of Exercise in Cardiovascular Diseases / Ambarish Pandey, Nitin Kondamudi, Carl J. Lovie
13. Nutrition, Diet, and Alcohol in Health and Cardiovascular Disease / Marta Guasch-Ferre, Frank Hu
14. Inflammation and Atherosclerosis / Hasan K. Siddiqi, Paul M. Ridker
15. Location and Level of Care, Education, Availability of Medicines, and Cardiovascular Mortality / Rajeev Gupta, Philip Joseph, Annika Rosengren, Salim Yusuf
16. Pathological Basis of Atherosclerotic Coronary Artery Disease / Jagat Narula, Renu Virmani, Navneet Narula, Borja Ibanez, Valentin Fuster
17. Pathogenesis of Coronary Thrombosis and Myocardial Infarction / Gemma Vilahur, Valentin Fuster, Borja Ibanez
18. ST-Elevation Myocardial Infarction / Borja Ibanez, Manesh Patel, Ines Garcfa-Lunar, Usman Baber, Jonathan Halperin, Valentin Fuster
19. Evaluation and Management of Non-ST-Segment Elevation Acute Coronary Syndromes / Eric R. Bates, David J. Moliterno, Manesh R. Patel
20. Mimickers of Atherosclerotic Myocardial Infarction / Jacqueline Saw, Jaya Chandrasekhar, Sarah Zaman, Harmony Reynolds
21. Chronic Coronary Syndromes / Sripal Bangalore, Ziad Ali, Jagat Narula, John Puskas, Gregg W. Stone
22. Cardiac Rehabilitation / Alan Rozanski, Soman Setareh-Shenas, Jagat Narula 23. Diseases of the Aorta
John A. Elefteriades, Bulat A. Ziganshin, Jonathan L. Halperin
24. Carotid Artery Disease / Christopher J. White
25. Cerebrovascular Disease / Hugo J. Aparicio, Vasileios-Arsenios Lioutas, Thanh N. Nguyen, Sudha Seshadri
26. Diagnosis and Management of Diseases of the Peripheral Arteries / Hillary Johnston-Cox, Daniella Kadian-Dodov, Jeffrey W. Olin
27. Acute Rheumatic Fever / Liesl Zuhlke, Jagat Narula, Mark Engel, Jonathan R. Carapetis
28. Aortic Stenosis / Marie-Annick Clavel, Marc R. Dweck, Martin Leon, Philippe Pibarot
29. Aortic Regurgitation, Mixed Valvular Heart Disease, and Heart Valve Prostheses / Patrizio Lancellotti, Alexandra Chitroceanu, Simona Sperlongano, Raluca Dulgheru, Adriana Postolache
30. Mitral Regurgitation / Jeroen J. Bax, Nina Ajmone Marson, Pieter van der Bijl, Hendrik Treede, Michele DeBonis, Bernard Prendergast, Bernard Iung, Victoria Delgado
31. Acquired Tricuspid Valve Diseases / Luigi P. Badano, Ana Pardo, Denisa Muraru, Jose Luis Zamorano
32. Mitral Stenosis / Vinay K. Bahl, Ravi S. Math
33. Infective Endocarditis / Ann F. Bolger
34. Electrophysiologic Anatomy, Mechanisms of Arrhythmias and Conduction Disturbances, and Genetics / Peng-Sheng Chen, Siew Yen Ho, Silvia G. Priori, Charles Antzelevitch 35. Supraventricular Tachycardia: Atrial Tachycardia, Atrioventricular Nodal Reentry, and Wolff-Parkinson-White Syndrome / David Spragg, Hugh Calkins
36. Atrial Fibrillation and Atrial Flutter / Anne B. Curtis, Tina Baykaner, Sanjiv M. Narayan
37. Ventricular Arrhythmias and Sudden Cardiac Death / Justin Hayase, Kalyanam Shivkumar, Jason S. Bradfield
38. Conduction System Disturbances and Bradyarrhythmias / Pugazhendhi Vijayaraman, Jeffrey Arkles, Jayanthi N. Koneru, David J. Callans
39. Diagnosis and Management of Syncope / Zachary D. Goldberger, Mohammed Ruzieh, Blair P. Grubb
40. Classification of Cardiomyopathies / Eloisa Arbustini, Barry J. Maron, Navneet Narula, Jagat Narula
41. Dilated Cardiomyopathy / Eloisa Arbustini, Alessandro Di Toro, Lorenzo Giuliani, Mario Urtis, G. William Dec, Jagat Narula
42. Hypertrophic Cardiomyopathy / Massimiliano Lorenzini, Perry M. Elliott
43. Cardiac Amyloidosis / Morie A. Gertz, Jagat Narula, Edgar Argulian, Sumeet S. Mitter
44. Restrictive Heart Diseases / Eloisa Arbustini, Alessandro Di Toro, Lorenzo Giuliani, G. William Dec, Jagat Narula
45. Left Ventricular Noncompaction / Eloisa Arbustini, Alessandra Serio, Lorenzo Giuliani, Nupoor Narula, Alessandro Di Toro
46. Myocarditis / Eloisa Arbustini, Alessandro Di Toro, Mario Urtis, Sean Pinney, Jagat Narula
47. Obstructive and Nonobstructive Coronary Disease in Heart Failure / Charlotte Lee, G. William Dec
48. Diagnosis and Management of Chronic Heart Failure / Muhammad Shahzeb Khan, Muthiah Vaduganathan, Javed Butler 49. Diagnosis and Management of Heart Failure with Preserved Ejection Fraction / João Pedro Ferreira, Kavita Sharma, Javed Butler
50. Evaluation and Management of Acute Heart Failure / Anuradha Lala, Kiron Mahmood, Eric J. Velazquez
51. Peripartum Cardiomyopathy / Uri Elkayam, Jena Pizula
52. Mechanical Circulatory Support and Heart Transplantation in Severe Heart Failure / Adam D. DeVore, Michelle M. Kittleson, Carmelo A. Milano, Jignesh K. Patel, Joseph G. Rogers, Jon A. Kobashigawa
53. Acute Pericarditis / James W. Lloyd, Sushil Allen Luis, Zi Ye, Jae K. Oh
54. Pericardial Effusion and Tamponade / Darryl J. Burstow, Sushil Allen Luis, Garvan C. Kane, Jae K. Oh
55. Constrictive Pericarditis / William R. Miranda, Kevin L. Greason, John M. Stulak, Jae K. Oh
56. Diagnosis and Management of Diseases of the Peripheral Venous System / Daniella Kadian-Dodov, Hillary Johnston-Cox, Jeffrey W. Olin
57. Pulmonary Hypertension / Yogesh N. V. Reddy, Barry A. Borlaug
58. Pulmonary Embolism / Victor F. Tapson
59. Cor Pulmonale: The Heart in Structural Lung Disease / Lewis J. Rubin
60. Sleep-Disordered Breathing / Shahrokh Javaheri, Dirk Pevernagie, Ali Javaheri
61. Evolution of Cardiac Critical Care / Venu Menon, Penelope Rampersad
62. Circulatory and Cardiogenic Shock / Gregory Serrao, Benjamin Bier, Umesh Gidwani 63. Sudden Cardiac: Death and Resuscitation / Sanjiv M. Narayan, James P. Daubert
64. Postoperative and Postprocedural Care in the Cardiac: Intensive Care Unit / Venu Menon
65. Anatomical and Physiological Classification of Adult Congenital Heart Disease / Jasmine Grewal, Alexander R. Opotowsky
66. Shunt Lesions / Ari M. Cedars, Shelby Kutty, Ashish Doshi
67. Right-Sided Lesions / Konstantinos Dimopoulos, Andrew Constantine
68. Left Heart Obstructive Lesions / Jennifer Cohen, David Ezon, Kenan Stern, Ali N. Zaidi
69. Single Ventricle Post Fontan Palliation: Tricuspid Atresia, Pulmonary Atresia, and Hypoplastic Left Heart Syndrome / Marie-A. Chaix, Paul Khairy
70. Complex Cyanotic Congenital Heart Disease: The "Mixing" Lesions / Rafael Alonso-Gonzalez and Danielle Massarella
71. Psychosocial Profiles in Adult Congenital Heart Disease and Transition to Adulthood / Philip Moons
72. Perioperative Evaluation for Noncardiac Surgery / Daniel Alyesh, Prashant Vaishnava, Kim A. Eagle
73. Anesthesia and the Patient with Cardiovascular Disease / David L. Reich, Elvera L. Baron, Joel A. Kaplan
74. Cardiovascular Disease in Patients with Cancer and Cardiovascular Complications of Cancer Therapies / Edward T.H. Yeh
75. Heart Disease in Chronic Kidney Disease / Jared Hooker, Omar Baber, Usman Baber
76. Rheumatologic Disease and the Cardiovascular System / Emily Carroll, Yousaf Ali 77. Cardiovascular Disease in Patients with HIV / Pravin Mango, Keir McCutcheon, Nqoba Tsabedze
78. Heart Disease in Pregnancy / Dan G. Halpern, Amy Sarma, Katherine E. Economy, Anne Marie Valente
79. Traumatic Heart Disease / T. Bruce Ferguson, Jr, Austin Rogers, Robert Allman
80. Women and Ischemic Heart Disease / Leslee J. Shaw, Viviany R. Taqueti, Nanette K. Wenger
81. Race, Ethnicity, Disparities, Diversity, and Heart Disease / Clyde W. Yancy
82. Cardiovascular Disease and Ageing: Cellular and Molecular Mechanisms / Zoltan Ungvari, Dao-Fu Dai, Bela Merkely, Anna Csiszar
83. Artificial Intelligence and Cardiovascular Care / John S. Rumsfeld, Bobak J. Mortazavi, Harlan M. Krumholz
84. Cardiovascular Manifestations of COVID-19 / Sean P. Pinney, Gennaro Giustino, Jeffrey I. Mechanick.Digital Access - PrintContents:
pt.
1. Problems of organizing his training. - Digital/PrintBruce E. Torbett, David S. Goodsell, Douglas D. Richman, editors.Summary: This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle.
Contents:
HIV Therapy: Looking Towards the Future
Computational challenges of structure-based approaches applied to HIV
Nucleocapsid Protein: A Desirable Target For Future Therapies Against HIV-1
HIV-1 integrase multimerization as a therapeutic target
Targeting HIV transcription: The quest for a functional cure
Targeting the HIV RNA Genome: High-Hanging Fruit Only Needs a Longer Ladder
HIV-1 Gag: An Emerging Target for Antiretroviral Therapy
The Triple Threat of HIV-1 Protease Inhibitors
Illustrations of the HIV Life Cycle. - DigitalBrian M. Devitt, Mustafa Karahan, João Espregueira-Mendes, editors.Summary: In this book, leading international thinkers in the still nascent field of orthopaedic sports medicine consider what the future holds and give their views on what we should be most worried about. The range of issues addressed is wide, encompassing technological threats, environmental concerns, big data and its ramifications, the influence of industry, academic ethics, and much more. Many of the identified dangers are not yet on the popular radar, and these are the principal focus of the book. On the other hand, attention is also paid to misplaced fears, with explanation as to why these anxieties can be laid to rest. The contributors are leading thinkers in the field and include original pioneers of sports medicine, senior and newly appointed orthopaedic surgeons, orthopaedic trainees, and sports medicine physicians. In addition, leaders of industry in sports medicine and allied health professionals from around the world share their fears. This compelling and thought-provoking book, published in collaboration with ISAKOS, will appeal to all stakeholders in orthopaedic sports medicine.
Contents:
Intro; Preface; In memorium: Dr John A Feagin, Jr.; Reference; Contents;
1: How Long Is a Piece of String?;
2: I Worry that Informal Logic Will Take Over from Formal Logic;
3: It's Not You, It's Me; References;
4: Are We Losing Our Profession Through the Loss of Leadership?; Reference;
5: BIG DATA: Revolution or Complication?;
6: The Influence of Industry;
7: Are We Stifling Innovation?;
8: Don't Get Dragged into the Gloom: Keep the Flame!; References;
9: Pseudoscience and False Avenues;
10: We'd Better Quit Now;
11: Academic Integrity and the God of Data; References
12: Research Funding: Finding a Balanc
e13: From Science to Daily Practice: A Huge Gap! The Example of Meniscus Surgery; References;
14: Living on the Edge;
15: The Last Generation of Doctors;
16: The Future of Orthopaedic Sports Medicine: It's the Human Connection;
17: The Meniscus Is the Most Important Piece of the Knee;
18: Is Medicine Now a Science or Still an Art?; Reference;
19: Let's Get Back to Basics; 19.1 No Scrum... No Win;
20: We Should Be Worried, About Being Worried!;
21: The End of Sports Surgery
22: Will Our Focus on Techniques and Technology to Improve Patient Outcomes Be at the Expense of a Loss of Clinical Judgement
?23: Are We Going Forward or Standing Still?; 23.1 Where Should We Look for Improvement?; 23.2 What We Should Be Worried About?;
24: Please Take Your Time: A Research Perspective;
25: What's in It for Me?;
26: Social Media in Sports Medicine; References;
27: Biologic and Regenerative Medicine: The Balance Between Promise and Proven;
28: There Are No Facts, Only Interpretations;
29: Increased Incidence of Sports Trauma in Children. Is It Time to Worry?
30: Persistent Lack of Patient Treatment Outcome Information for Patients, Therapists, and Surgeon
s31: The Perils and Potentials of Biologic Therapies;
32: Am I a Robot or a Surgeon?; 32.1 Prevention Is Better than Cure!;
33: Who Will Guard the Guardians?;
34: Don't Wait to Worry!; Reference;
35: The Threat of Fake News!; References;
36: The Big Bang and Its Fall Out;
37: First the Process, Then the Art of Medicine? The Gruyère Theory;
38: The Complexity of a 'Rope';
39: If You Don't Know Where You Are Going, Any Road Will Take You There!; References;
40: What's the Use in Worrying?
41: High-Technology Technicians Versus Bedside Doctors; 41.1 Reducing or Eliminating the Hospital Stay: The New Paradigm; 41.2 From Navigation to Robotics; 41.3 Biological Treatments: The New Frontier;
42: Surgery Is Overvalued and Rehabilitation Undervalued Following Anterior Cruciate Ligament Injury; 42.1 Rehabilitation Is Undervalued; References;
43: The Professional Responsibility of Orthopaedic Sports Medicine Surgeons as Advocates for Sports Injury Prevention; References;
44: Digitalization and Machine Learning;
45: Worried About the Vision; 45.1 Perspective; 45.2 Prevention; 45.3 Advocacy.Digital Access Springer 2020
- The Fabrica of Andreas Vesalius : a worldwide descriptive census, ownership, and annotations of the 1543 and 1555 editions — Fetal cardiology-- a practical approach to diagnosis and management (138)
- Fetal growth restriction : current evidence and clinical practice — Food bioactives and health (138)
- Food biopolymers : structural, functional and nutraceutical properties — Frontiers of hormone research (138)
- Frontiers of neurology and neuroscience — The Future of orthopaedic sports medicine : What should we be worried about? (136)
Popular Books
- Harrison's Principles of Internal Medicine
- AAP Red Book Online
- Robbins & Cotran Pathologic Basis of Disease
- Sabiston Textbook of Surgery
- Nelson's Textbook of Pediatrics
- Surgical Exposures in Orthopaedics
- Mandell, Douglas, & Bennett's Principles & Practice of Infectious Diseases
- Red Book Online
- ICU Book
- Primary Care Medicine
- Campbell-Walsh Urology
Access restricted to Stanford community
Lane Library Bookmarklet
To install, drag this button to your browser bookmarks or tools bar.
Bookmark on Other Websites
- To Install, Right Click this Button.
- Select "Add to Favorites" (click “Continue” if you see a security alert)
- From the "Create in" menu, select “Favorites Bar” (IE8, IE9) to install
- Once installed it will look like this
- Click "Bookmark on Lane" to bookmark any webpage
- Your saved bookmark will appear on this page
Can't Find It?
Browse by Publisher
Biomedical Publishers
- AccessMedicine
- Springer Protocols
- Books@Ovid
- ClinicalKey
- MyiLibrary
- Stat!Ref
- Lange Series
- National Academy Press
- NCBI Bookshelf
- PsychiatryOnline
- CogNet
- Thieme Atlases
Bioresearch Publishers
- Safari Tech Books
- SpringerLink
- CRCnet base
- MyiLibrary
- ebrary
- EBSCOhost (Choose Research Databases... eBook Collection)
Beyond Stanford
A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more.
Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.
MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available. DynaMed is a clinical information resource used to answer questions quickly at the point-of-care. Easy-to-interpret Levels of Evidence help clinicians rapidly determine the quality of the available evidence.Biomedical and pharmacological abstracting and indexing database of published literature, by Elsevier. Embase® contains over 32 million records from over 8,500 currently published journals (1947-present) and is noteworthy for its extensive coverage of the international pharmaceutical and alternative/complementary medicine literature.
Scopus is the largest abstract and citation database of peer-reviewed literature: scientific journals, books and conference proceedings. A drug information resource containing: American Hospital Formulary System (AHFS), drug formulary for Lucile Packard Children's Hospital (LPCH) and Stanford Hospital & Clinics (SHC), Lexi-Drugs (adverse reactions, dosage and administration, mechanism of action, storage, use, and administration information), Lexi-Calc, Lexi-ID, Lexi-I.V. Compatibility (King Guide), Lexi-Interact, and Lexi-PALS. Cumulative Index to Nursing and Allied Health Literature (CINAHL) contains coverage of nursing and allied health literature. A knowledge database that provides access to topic reviews based on over 6000 clinically relevant articles. The evidence-based content, updated regularly, provides the latest practice guidelines in 59 medical specialties. Provides critical assessments of systematic reviews compiled from a variety of medical journals. Selects from the biomedical literature original studies and systematic reviews that are immediately clinically relevant and then summarizes these articles in an enhanced abstract with expert commentary.Multidisciplinary coverage of over 10,000 high-impact journals in the sciences, social sciences, and arts and humanities, as well as international proceedings coverage for over 120,000 conferences.
Includes cited reference searching, citation maps, and an analyze tool.
Features systematic reviews that summarize the effects of interventions and makes a determination whether the intervention is efficacious or not.
Cochrane reviews are created through a strict process of compiling and analyzing data from multiple randomized control trials to ensure comprehensiveness and reliability.
Provides systematic coverage of the psychological literature from the 1800s to the present through articles, book chapters and dissertations. PIER (Physicians' Information and Education Resource) is a Web-based decision-support tool designed for rapid point-of-care delivery of up-to-date, evidence-based guidance for primary care physicians. Cochrane Central Register of Controlled Trials (CENTRAL) provides access to 300,000 controlled trials that have been identified the Cochrane Collaboration. Provides drug information targeted for patients. A continually updating drug monograph. ECRI Guidelines Trust: A comprehensive database of evidence-based clinical practice guidelines and related documents. MedlinePlus: A repository of health information from the National Library of Medicine. Links are from trusted sites. No advertising, no endorsement of commercial companies or products LPCH CareNotes via MicroMedex: Patient education handouts customized by LPCH clinical staff Micromedex Lab Advisor: Evidence based laboratory test information Provides patient handouts from the American Academy of Family Physician.Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities.
In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.
A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.A web-based, decision support system for infectious diseases, epidemiology, microbiology and antimicrobial chemotherapy. The database, updated weekly, currently includes 337 diseases, 224 countries, 1,147 microbial taxa and 306 antibacterial (-fungal, -parasitic, -viral) agents and vaccines.
Over 10,000 notes outline the status of specific infections within each country.
Provides online, full-text access to Springer's journal titles as well as journals from other publishers.
Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.
Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present. A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.