BookYunbo Luo.
Summary: This book highlights the development of a functional nucleic acid based biosensor detection method in the context of food safety. Although there have been major advances in food processing technology in both developed and developing countries, food safety assurance systems are generally becoming more stringent, in response to growing (both real and perceived) food safety problems. These problems are due in part to foodborne microorganisms, heavy metals, and small chemical molecules (biological toxins, pesticide residues, and veterinary drug residues), etc. In addition, the nucleic acid biomarkers (DNA methylation, microRNA, and circRNA) induced by these risk factors are also closely related to food safety. Accordingly, this book offers a brief guide to targets and strategies in functional nucleic acid based biosensors for food safety detection. Divided into several chapters that focus on various respective targets, it will be a valuable resource for students and researchers in the fields of biosensor detection, food science etc.
Contents:
Intro; Preface; Contents;
Chapter 1: Functional Nucleic Acid Based Biosensors forFood Safety Detection; 1.1 Food Safety Burden: Safer Food Saves Lives; 1.2 Food Safety Risk Factors: Significant Proportion Can BePrevented; 1.2.1 Microorganisms; 1.2.2 Genetically Modified Organism (GMO); 1.2.3 Heavy Metal Ion; 1.2.4 Chemical Small Molecules; 1.2.5 Nucleic Acid Biomarkers; 1.3 Biosensor: ATrend Toward Rapid andOn-Site Detection; 1.3.1 Optical Biosensor; 1.3.2 Electrochemical Biosensor; 1.3.3 Gravimetric Biosensor; 1.4 Functional Nucleic Acid: Powerful Tools toImprove Performance. 1.4.1 Nucleic Acid asTarget Recognition ElementDNA-Based Biosensors; Aptamer-Based Biosensors; DNAzyme-Based Biosensors; Artificial Nucleic Acid-Based Biosensors; 1.4.2 Nucleic Acid asSignal Amplification; DNA Amplification Techniques; G-Quadruplex Amplification Techniques; 1.4.3 Nucleic Acid as3D Nanostructure; References;
Chapter 2: Functional Nucleic Acid Based Biosensor forMicroorganism Detection; 2.1 Introduction; 2.2 The Construction ofFunctional Nucleic Acid Based Biosensors forMicroorganism Detection andIts Technological Element. 2.2.1 Signal Recognization andTransduction ofFunctional Nucleic Acid Based Biosensor2.2.2 Signal Transduction Elements; 2.2.3 Signal Amplification ofFunctional Nucleic Acid Based Biosensor; 2.2.4 Signal Output Systems ofFunctional Nucleic Acid Based Biosensor; 2.3 Functional Nucleic Acid Based Biosensors forMicroorganism Detection; 2.3.1 Aptamer Based Biosensors forMicroorganism Detection; 2.3.2 Functional Nucleic Acid Based Colorimetric Biosensors forMicroorganism Detection; 2.3.3 Lateral Flow Nucleic Acid Based Biosensors (LFNABs) forMicroorganism Detection. 2.3.10 Gold Nanoparticle (AuNP)-Functional Nucleic Acid Based Biosensors forMicroorganism Detection2.3.11 Silver Nanoparticle (AgNP)-Functional Nucleic Acid Based Biosensors forMicroorganism Detection; 2.3.12 Nanozyme-Functional Nucleic Acid Based Biosensors forMicroorganism Detection; 2.3.13 Magnetic Nanoparticle (MNP)-Functional Nucleic Acid Based Biosensors forMicroorganism Detection; 2.3.14 Functional Nucleic Acid Based Fluorescence Biosensors forMicroorganism Detection; 2.3.15 Functional Nucleic Acid Based Electrochemical Biosensors forMicroorganism Detection. 2.3.4 PCR-Functional Nucleic Acid Based Biosensors forMicroorganisms Quantitative Detection2.3.5 Isothermal Amplification-Functional Nucleic Acid Based Biosensors forMicroorganism Detection; 2.3.6 Functional Nucleic Acid Based High-Throughput Biosensors forMicroorganism Detection; 2.3.7 Functional Nucleic Acid Based Biosensor forLiving or Dead Bacteria Detection; 2.3.8 Artificial Nucleic Acid Based Biosensors forMicroorganism Detection; 2.3.9 DNAzyme Based Biosensors forMicroorganism Detection.