BookJean-Paul Latgé, editor.
Summary: This book illustrates, that the fungal cell wall is critical for the biology and ecology of all fungi and especially for human fungal pathogens. Readers will learn, that the composition of the fungal cell wall is a unique structure, which cannot be found in the human host. Consequently, the chapters outline, how the immune systems of both animals and humans have evolved to recognize conserved and unique elements of the fungal cell wall. As an application example, the authors also show, that the three-dimensional structures of the cell wall are excellent targets for the development of antifungal agents and chemotherapeutic strategies. With the combination of biological findings and medical outlooks, this volume is a fascinating read for scientists, clinicians and biomedical students.
Contents:
Synthesis of mimicks
Melanin
Rodlets and cell wall surface proteins
Alpha 1,3 and Beta 1,3 glucans and remodelling
Chitin
Cell wall PAMPs and PRRs in mammalians
Extracellular polysaccharides and biofilms
Cell wall drugs and resistance mechanisms
GPI proteins and cell wall
Cell wall and morphogenesis
Carbohydrate active enzymes in fungi B
Glucanases and chitinases
Respiration and cell wall synthesis
Cell wall and environment. .
Location
Version
Call Number
Items