BookKazunari Tominaga, Hiroaki Kusunoki, editors.
Summary: The research and outcomes presented in this book gather evidence concerning both the pathogenesis and treatment of functional dyspepsia. It provides the latest information on this common non-organic disease, indicating its characteristic pathogenesis based on the brain-gut interaction and micro-environment and evidence gleaned from clinical treatment. Since the pathogenesis is associated with psychology, neurology, endocrinology and bacteriology in addition to gastroenterological physiology, it is often intractable and finding a suitable treatment rationale is challenging. Furthermore, the pathogenesis varies around the world and the efficacy of treatment using standard drugs varies among different populations worldwide; accordingly, this book highlights evidence gained in clinical trials in Japan. Functional Dyspepsia is a milestone produced by respected experts. Addressing unique topics and new findings of treatment including challenging and/or future rationales, it offers an invaluable resource for general clinicians, gastroenterologists, and basic researchers alike.
Contents:
PART I: Etiology.-Chapter 1: Definition & Prevalence
Chapter 2: Genetic Factor
Chapter 3: Environmental Factors
PART II: Pathophysiology
Chapter 4: Neuro-gastroenterology: Central & Autonomic Nervous System.-Chapter 5: Neuro-gastroenterology: Enteric Nervous System
Chapter 6: Neuro-gastroenterology: Esophago-gastric Function (Motility) .-Chapter 7: Neuro-Gastroenterology: Gastro-duodenal Function (Motility) and Ultrasonographic Assessment.-Chapter 8: Ghrelin and Functional Dyspepsia
Chapter 9: Psycho-gastroenterology
Chapter 10: Visceral Hypersensitivity Through Transient Receptor Potential Vanilloid 1 Channels (TRPV1) in Functional Dyspepsia.-PART III: Treatment.-Chapter 11: Efficacy of Acid Suppression Therapy.-Chapter 12: Prokinetics.-Chapter 13: Herbal Medicine.-PART IV: Recent Special Topics: Future Treatment Possibility
Chapter 14: Gut Dysbiosis and Its Treatment in Patients with Functional Dyspepsia
Chapter 15: Visceral Hypersensitivity in Functional Dyspepsia (FD)
Therapeutic Approaches to FD Based on Suppression of Visceral Hypersensitivity
Chapter 16: Pancreatic Exocrine Function.