Bookedited by Stephen B. Dunnett and Anders Björklund.
Contents:
Part A: Mechanisms and use of neural transplants for brain repair / Stephen B. Dunnett and Anders Björklund
Reprogramming of somatic cells: iPS and iN cells / Vania Broccoli
Brain repair from intrinsic cell sources: turning reactive glia into neurons / Olof Torper and Magdalena Götz
Ex vivo gene therapy for the treatment of neurological disorders / Genevieve Gowing , Soshana Svendsen and Clive N. Svendsen
Preparation, characterization and banking of clinical-grade cells for neural transplantation: scale up, fingerprinting and genomic stability of stem cell lines / Ammar Natalwala and Tilo Kunath
Regulatory considerations for pluripotent stem cell therapies / Melissa K. Carpenter
Strategies for bringing stem cell-derived dopamine neurons to the clinic: a European approach (STEM-PD) / Agnete Kirkeby, Malin Parmar and Roger A. Barker
Strategies for bringing stem cell-derived dopamine neurons to the clinic: the NYSTEM trial / Lorenz Studer
Strategies for bringing stem cell-derived dopamine neurons to the clinic: the Kyoto trial / Jun Takahashi
From open to large-scale randomised cell transplantation trials in Huntington's disease: lessons from the multicentric intracerebral grafting in Huntington's Disease trial (MIG-HD) and previous pilot studies / Anne-Catherine Bachoud-Lévi
Pluripotent stem cell-derived neurons for transplantation in Huntington's disease / Meng Li and Anne E. Rosser
Advanced imaging of transplant survival, fate, differentiation, and integration / Nadja Van Camp, Elsa Diguet and Philippe Hantraye
Rehabilitation training in neural restitution / Susanne Clinch, Monica Busse, Mate D. Döbrössy and Stephen B. Dunnett. Part B: Stem cell transplantation for spinal cord injury repair / Paul Lu
Plasticity and regeneration in the injured spinal cord after cell transplantation therapy / Satoshi Nori, Masaya Nakamura and Hideyuki Okano
Transplantation of GABAergic interneurons for cell-based therapy / Julien Spatazza, Walter R. Mancia Leon and Arturo Alvarez-Buylla
Rebuilding CNS inhibitory circuits to control chronic neuropathic pain and itch / Joao M. Braz, Alex Etlin, Dina Juarez-Salinas, Ida J. Llewellyn-Smith and Allan I. Basbaum
From transplanting Schwann cells in experimental rat spinal cord injury to their transplantation into human injured spinal cord in clinical trials / Mary B. Bunge, Paula V. Monje, Aisha Khan and Patrick M. Wood
Recruitment of endogenous CNS stem cells for regeneration in demyelinating disease / Natalia A. Murphy and Robin J.M. Franklin
Progenitor Cell-Based Treatment of Glial Disease / Steven A. Goldman
Pluripotent stem cells and their utility in treating photoreceptor degenerations / Nozie D. Aghaizu, Kamil Kruczek, Anai Gonzalez-Cordero, Robin R. Ali and Rachael A. Pearson
Stem cell-derived retinal pigment epithelium transplantation for treatment of retinal disease / Britta Nommiste, Kate Fynes, Victoria E. Tovell, Conor Ramsden, Lyndon da Cruz and Peter Coffey
Transplantation of reprogrammed neurons for improved recovery after stroke / Zaal Kokaia, Daniel Tornero and Olle Lindvall.