BookIftekhar Mahmood, Gilbert Burckart, editors.
Contents:
1. Pediatric Drug Development and the Regulatory Changes That Are Creating the Science of Pediatric Dosing / Gilbert J. Burckart
2. Pediatric Physiology / Iftekhar Mahmood
3. Developmental Pharmacology: Impact on Pharmacokinetics and Pharmacodynamics
of Drugs / Iftekhar Mahmood
4. Pediatric Clinical Trial Design and Dosing / Dionna Green and Valerie Amspacher
5. Application of Allometric Principles in Pediatric Drug Development / Iftekhar Mahmood
6. Population Pharmacokinetics in Pediatric Drug Development / Jeremiah D. Momper , John Bradley , and Brookie M. Best
7. Scaling Dose-Exposure-Response from Adults to Children / Ine Skottheim Rusten , Anna Nordmark , Susan Cole , Joseph F. Standing , Sofi a Friberg Hietala , Wei Zhao , Valeria Gigante , Anna Karin Hamberg , Gérard Pons , María Jesús Garrido , Johannes Taminiau , Norbert Benda , Frederike Lentz , Flora Musuamba Tshinanu , Andrew Thomson , Paolo Tomasi , Cecile Ollivier , Ralf Herold , and Efthymios Manolis
8. Applications of Physiologically Based Pharmacokinetic (PBPK) Models for Pediatric Populations / Peng Duan , Jeffrey Fisher , and Jian Wang
9. Perinatal Pharmacology and Maternal/Fetal Dosing / Iftekhar Mahmood, Gilbert J. Burckart and Robert M. Ward.