ArticleBrettes JP, Tourne CE, Gandar R.
J Gynecol Obstet Biol Reprod (Paris). 1976 Jul-Aug;5(5):637-44.
Using an immunological technique limits of normal levels of AFP in maternal blood have been worked out during pregnancy from a series of 3010 samples of blood. Comparing mean curves for the levels of AFP in mothers suffering from anaemia and diabetes with normal curves shows that there is a significant rise in these levels in the third trimester of pregnancy. The possible mechanisms and their relationship to the variation levels of AFP are discussed.