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- ArticleWein AJ, Hanno PM, Dixon DO, Raezer DM, Benson GS.J Urol. 1978 Sep;120(3):330-1.A double-blind study of the effects of placebo and oral bethanechol chloride (25, 50 and 100 mg.) on the carbon dioxide cystometrogram of the normal male adult was done. Statistical analysis of the data showed no significant dose-response relationship for any of the parameters measured.