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  • Book
    Jan Tachezy, editor.
    Summary: "Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes, 2nd edition" provides a comprehensive summary of the current knowledge on these organelles, which occur in unicellular, often parasitic organisms, including human pathogens. It discusses the discovery of these widely distributed organelles, as well as their evolution and recent advances in the study of their structure and function. The book also describes their properties, such as protein import, structure, metabolism and adaptation, their proteome and their role in drug activation and resistance. The book will appeal to researchers and students interested in biology and medicine, and to those who are mainly interested in basic science-cell biology, parasitology, microbiology, evolution etc., but also to those interested in organelles as potential targets for chemotherapy.

    Contents:
    Chapter 1: Introduction
    Chapter 2: The evolution of oxygen independent energy metabolism in eukaryotes with hydrogenosomes and mitosomes
    Chapter 3: Protein Import into Hydrogenosomes and Mitosomes
    Chapter 4: Structure of the Hydrogenosome
    Chapter 5: Hydrogenosomes of Anaerobic Ciliates
    Chapter 6: Metabolism of Trichomonad Hydrogenosomes
    Chapter 7: Hydrogenosomes of Anaerobic Fungi: an Alternative Way to Adapt to Anaerobic Environments
    Chapter 8: The proteome of T. vaginalis hydrogenosomes
    Chapter 9: Mitosomes in parasitic protists
    Chapter 10: The Mitochondrion-Related Organelles of Crypto-sporidium species
    Chapter 11: The Mitochondrion-Related Organelles of Blastocystis
    Chapter 12: Mitochondrion-related organelles in free-living protists
    Chapter 13: Protists without mitochondria, how it may happen?
    Digital Access Springer 2019
  • Article
    Christensen P, Sjöholm AG, Holm S, Hovelius B, Mårdh PA.
    Acta Pathol Microbiol Scand B. 1978 Feb;86(1):29-33.
    109 streptococcal strains, belonging to diverse serological groups and types, were investigated as regards their capacity to bind IgG aggregates in the presence of fresh serum. Strains capable of such binding were not found in groups B,C,D,E,G,L,M or N. Such binding was restricted to a few types of group A streptococci: the potentially nephritogenic types 2, 6 and 12, and four strains belonging to type M 39, M 46 and M 22 or M 62, the nephritogenic capacity of which is unknown. Two of five strains isolated from patients with acute post-stretococcal glomerulonephritis (AGN) and 19/28 type T 12, SOR-strains, isolated during an epidemic in a kindergarten with associated cases of AGN, were found to bind aggregates. The findings suggest a possible association between capacity to bind aggregates in the presence of serum and the serological types of group A streptococci involved in acute nephritis following pharyngeal infection.
    Digital Access Access Options