BookJan Tachezy, editor.
Summary: "Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes, 2nd edition" provides a comprehensive summary of the current knowledge on these organelles, which occur in unicellular, often parasitic organisms, including human pathogens. It discusses the discovery of these widely distributed organelles, as well as their evolution and recent advances in the study of their structure and function. The book also describes their properties, such as protein import, structure, metabolism and adaptation, their proteome and their role in drug activation and resistance. The book will appeal to researchers and students interested in biology and medicine, and to those who are mainly interested in basic science-cell biology, parasitology, microbiology, evolution etc., but also to those interested in organelles as potential targets for chemotherapy.
Contents:
Chapter 1: Introduction
Chapter 2: The evolution of oxygen independent energy metabolism in eukaryotes with hydrogenosomes and mitosomes
Chapter 3: Protein Import into Hydrogenosomes and Mitosomes
Chapter 4: Structure of the Hydrogenosome
Chapter 5: Hydrogenosomes of Anaerobic Ciliates
Chapter 6: Metabolism of Trichomonad Hydrogenosomes
Chapter 7: Hydrogenosomes of Anaerobic Fungi: an Alternative Way to Adapt to Anaerobic Environments
Chapter 8: The proteome of T. vaginalis hydrogenosomes
Chapter 9: Mitosomes in parasitic protists
Chapter 10: The Mitochondrion-Related Organelles of Crypto-sporidium species
Chapter 11: The Mitochondrion-Related Organelles of Blastocystis
Chapter 12: Mitochondrion-related organelles in free-living protists
Chapter 13: Protists without mitochondria, how it may happen?