ArticleMel'nikov OF, Krivokhatskaia LD, Povolotskiĭ IaL.
Biull Eksp Biol Med. 1977 Mar;83(3):302-3.
The authors investigated some functional properties of interferon and the macrophages migration inhibitory factor (MIF) obtained by stimulation of human tonsil lymphocytes with the virus of Newcastle disease (NDV) or O-streptolysin. Both the interferon and MIF inhibited actively the migration of human tonsil cells, but differed by the anti-viral activity, and sensitivity to heating at 56 degrees C for 30 min. Stimulation of human tonsil lymphocytes with NDV leads to production of a more wide range of delayed hypersensitivity mediators than stimulation with O-streptolysin.