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  Reactivity of HLA typing sera against cultured lymphoblastoid cell lines and purified peripheral B and T cells from the same original donors.

  Nakayama E, Itakura K.

  Jpn J Exp Med. 1977 Oct;47(5):425-7.

  Anomalous cytotoxicity reactions are observed in some HLA typing sera when cultured lymphoid cells are used as targets. These extra reactions are also detected when the purified B cells from the original donors of the cell lines are used. This observation strongly indicates that these extra reactions are directed to the B cell alloantigens which are normally expressed on B cells of the original donor.

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