ArticleNaumann GO, Völcker HE.
Klin Monbl Augenheilkd. 1977 Sep;171(3):352-9.
Among 81 eyes enucleated after severe trauma, two eyes showed a peculiar granulomatous reaction around a bloodcoagulum. The bloodcoagulum is surrounded by a granulomatous infiltration of epithelioid and giant cells containing haemotoidin; peripheral to this there are haemosiderin containing makrophages and granulation and scartissue as well as an unspecific lymphocytic infiltration of uvea and retina. There are also signs of persistent hypotony. The similarity to endophthalmitis phacoanaphylactica is stressed. It is postulated that the endophthalmitis haemo-granulomatosa is analogous to sympathetic uveitis, and phacoanaphylactica endophthalmitis represents a peculiar reaction to autologous intraocular tissue, which may occur in unspecific types of reaction, makrophagocytic reactions and as a granulomatous type. The differentialdiagnosis is discussed as well as possible clinical implications.