BookJun Yu, editor.
Summary: This book covers state-of-the-art topics covering evidences indicate that the gut microbiota can be harnessed for cancer prevention as well as to modulate the efficacy of chemotherapy and immunotherapy. This book includes: 1) characterization of the dysregulated microbiome in gastrointestinal cancers (Chapters 1-6); 2) the molecular mechanism of action of gut microbiota via microbial metabolites and direct interaction with host cancer or immune cells (Chapters 7-11); 3) key methodologies for studying the role of gut microbiota in cancers (Chapters 12-13); and 4) the potential application of gut microbes for the prevention and treatment of gastrointestinal cancers (Chapters 14-17). The contributors are international experts in molecular and cellular biology, microbiology, metabolomics, bioinformatics and physician scientists to provide in-depth reviews of this subject. This book provides a rich resource of information on this important topic for graduate students, basic researchers and physicians.
Contents:
Introduction
Gut microbiome in health and diseases
Microbiome in colorectal cancer
Microbiome in gastric cancer
Microbiome in liver cancer
Virus, fungi and archaea in gastrointestinal cancer
Microbial metabolomics in gastrointestinal cancer
Diet and gut microbiome in gastrointestinal cancer
Diet and gut microbiome in fatty liver and its associated liver cancer
Host-microbiome interaction in gastrointestinal cancer
Gut microbiome and immune responses in gastrointestinal cancer
Animal models in the study of microbiome in gastrointestinal cancer
High-throughput sequencing data analyses for microbiome profiling
Gut microbiota modulation: probiotics and prebiotics in gastrointestinal cancer
Roles of gut microbiota in efficacy of anticancer treatment of gastrointestinal cancer
Targeting gut microbiota to treat gastrointestinal cancer.