Bookeditors, Lea A. Harrington, PhD,
... Show More Professor Department of Medicine University of Montreal Institute for Research in Immunology and Cancer Pavilion, Montreal, Quebec, Canada, Ian F. Tannock, MD, PhD, DSc, Emeritus Professor of Medicine and Medical Biophysics Princess Margaret Cancer Centre and University of Toronto, Toronto, Ontario, Canada, Richard P. Hill, PhD, Professor Emeritus Department of Medical Biophysics Princess Margaret Cancer Centre University of Toronto, Toronto, Ontario, Canado, David W. Cescon, MD, Phd, Medical Oncologist and Clinician Scientist Princess Margaret Cancer Centre University of Health Network Assistant Professor of Medicine University of Toronto, Toronto, Ontario.
Summary: "Covers cancer causation, cancer biology, and the biology underlying cancer treatment, for trainees in both clinical and research areas of oncology"-- Provided by publisher
Contents:
Introduction to cancer biology
Methods of molecular analysis
Epigenetics
Cancer epidemiology
Carcinogenesis
Cellular signaling
Oncogenes and tumor-suppressor genes
Cell proliferation and death
Genomic stability and DNA repair
Tumor progression and metastasis
Angiogenesis
Tumor growth, microenvironment, metabolism, and hypoxia
Cancer heterogeneity
Imaging in oncology
Molecular and cellular basis of radiotherapy
Tumor and normal tissue response to radiotherapy
Discovery and evaluation of anticancer drugs
Anticancer chemotherapy, pharmacology, and mechanisms of resistance
Molecular targeted therapies
Hormones and cancer
The immune system and immunotherapy
Guide to clinical studies