BookCrystal Karakochuk, Michael B. Zimmermann, Diego Moretti, Klaus Kraemer, editors.
Summary: Understanding the causes of anemia is critical to inform appropriate strategies to prevent and treat anemia, particularly to reduce the risk of anemia and the burden of disease. The strength of this book lies in its cross-disciplinary nature. This publication summarizes the current state of evidence on the multifactorial causes of anemia, with a specific focus on nutritional anemia. The chapter authors are leading experts in nutrition and global health. The introductory chapters provide an overview of the global burden of anemia prevalence, the economic implications and functional consequences of anemia, and the significance of these factors to guide policy and programs. Subsequent chapters provide current evidence on iron and other micronutrient metabolism and homeostasis in regards to anemia, the multifactorial contributors to anemia (e.g. infection and genetics), and the interactions between nutrients that may contribute to anemia. The summarizing chapters detail program and policy approaches to treat, prevent and reduce anemia in the global context. Nutritional Anemia is a comprehensive resource for those involved in global health and nutrition policy, strategy, programming, or research, and serves as a guide for how government, NGO, and international agencies can effectively treat, prevent and reduce anemia globally.
Contents:
Worldwide Prevalence and Progress in Anemia Reduction
The Economics of Addressing Nutritional Anemia
Iron Biology: Metabolism and Homeostasis
Laboratory Methods for Measurement of Anemia and Iron Status
Interpretation of Biomarkers and Diagnosis of Nutritional Status
Anemia and Iron Deficiency in Disease
Nutritional Anemia in Special Population Groups (children, elderly, pregnancy/lactation, vegetarians)
Sources of Iron Intake: Diet, Supplemental, Environmental
Bioavailability: Inhibitors and Enhancers of Iron Absorption
Food Fortification with Iron: Policy and Considerations
Genetic Hemoglobinopathies and their Contribution to Anemia
Role of B-vitamins in Nutritional Anemia
Oxidative Stress and Vitamin E in Anemia
Vitamin D and Hepcidin in Nutritional Anemia
Infection and Inflammation in the Etiology and Assessment of Iron Deficiency of Anemia
Iron Infection and the Immune System
Anemia in Sever Undernutrition (malnutrition)
Interactions between Iron and other Minerals in the Etiology of Anemia
Iron and the Gut Microbiota
An Overview of the Functional Significance of Iron Deficiency (Cognitive, Behavioral)
Designing Effective Programs for Anemia Prevention, Treatment, and Reduction
Market-based Approaches for Anemia Prevention, Treatment, and Reduction
Safety of Interventions to Reduce Nutritional Anemia
Novel Approaches to Iron Supplementation
Food-based Approaches to Combating Iron Deficiency
Conclusions and Research Agenda.