BookChing Yee Oliver Wong, Dafang Wu.
Summary: This casebook details key information and findings in PET oncology imaging. PET CT has been increasingly utilized in clinical practice for diagnostic evaluation, initial staging and restaging of malignancies, and plays an important role in optimal patient care. Although F-18 fluorodeoxyglucose (FDG) is still the dominant radioactive tracer in oncology PET imaging services, a handful of new tracers have recently gained the US FDA approval, such as Ga-68 or Cu-64 DOTATATE for carcinoid/neuroendocrine tumors, and F-18 Fluciclovine (AXUMIN) and PSMA for recurrent or metastatic prostate cancers. Clinical interpretation of PET CT oncology scans is often challenging, due to the specific nature of these positron emission radioactive tracers, variable background tracer activities in different organs/tissues with normal variants, complex tumor biology, and wide-ranged treatment responses, especially with emerging and new molecular and immune therapy agents. This book serves as a hands-on casebook on how to interpret oncologic PET CT studies in clinical services with a special emphasis on phenotypic nature of oncologic imaging. Clinical cases are presented in a way that is familiar to physicians from their training in nuclear medicine services. Each case starts with key clinical information or background, followed by well-displayed PET CT images, along with pertinent questions highlighting the key findings and explanation, as well as the importance in diagnosis and clinical implications on separate pages. Clinical and imaging key findings and final impressions are highlighted throughout along with qualitative and quantitative demonstrations of phenotypic nature of modern PET imaging. Written by two nuclear medicine PET specialists with decades of first-hand clinical experience, this is an ideal guide for nuclear medicine attending physicians, diagnostic radiologists, medical and surgical oncologists, and relevant trainees.
Contents:
Intro
Preface
Acknowledgments
Contents
Chapter 1: Case 1: Double Pulmonary Nodules
1.1 Case 1: Interpretation and Teaching
Reference
Chapter 2: Case 2: Nodular Sclerosing Hodgkin's Lymphoma
2.1 Case 2: Interpretation and Teaching
2.2 Assessment of Treatment Response
Reference
Chapter 3: Case 3: Transformation in Non-Hodgkin's Lymphoma
3.1 Case 3: Interpretation and Teaching
Reference
Chapter 4: Case 4: Metabolic Phenotypes in Different Neoplasms
4.1 Case 4: Interpretation and Teaching
Reference Chapter 5: Case 5: Marrow Involvement in Non-Hodgkin's Lymphoma
5.1 Case 5: Interpretation and Teaching
Reference
Chapter 6: Case 6: Hip Pain in Lymphoma
6.1 Case 6: Interpretation and Teaching
Reference
Chapter 7: Case 7: Prostate Cancer-Specific PET Agent with Rising PSA
7.1 Case 7: Interpretation and Teaching
Reference
Chapter 8: Case 8: Brain Tumor Evaluation
8.1 Case 8: Interpretation and Teaching
Reference
Chapter 9: Case 9: Metabolic Phenotype in a Slowly Growing Lung Cancer
9.1 Case 9: Interpretation and Teaching
Reference Chapter 10: Case 10: Metabolic Phenotype in Lung Metastasis from Colon Cancer
10.1 Case 10: Interpretation and Teaching
Reference
Chapter 11: Case 11: PET and Bone Scans in Non-Small Cell Lung Cancer
11.1 Case 11: Interpretation and Teaching
Reference
Chapter 12: Case 12: Neuroendocrine Cancer of the Ileum
12.1 Case 12: Interpretation and Teaching
Reference
Chapter 13: Case 13: Coexisting Different PET Tumor Phenotypes
13.1 Case 13: Interpretation and Teaching
Reference
Chapter 14: Case 14: COVID-19 Vaccination and Lung Nodules 14.1 Case 14: Interpretation and Teaching
Reference
Chapter 16: Case 16: Breast and Ovarian Uptake
16.1 Case 16: Interpretation and Teaching
References
Chapter 17: Case 17: Rising PSA in Radical Prostatectomy for Prostate Cancer
17.1 Case 17: Interpretation and Teaching
Reference
Chapter 18: Case 18: Concurrent Lung and Brain Metastatic Cancer
18.1 Case 18: Interpretation and Teaching
Reference
Chapter 19: Case 19: Tumor Phenotypes in Metastatic Prostate Cancer
19.1 Case 19: Interpretation and Teaching
Reference Chapter 20: Case 20: Metastatic Recurrent Melanoma
20.1 Case 20: Interpretation and Teaching
Reference
Chapter 21: Case 21: Post-prostatectomy for Prostate Cancer with Rising PSA
21.1 Case 21: Interpretation and Teaching
Reference
Chapter 22: Case 22: Left Adrenal Mass
22.1 Case 22: Interpretation and Teaching
Reference
Chapter 23: Case 23: Cutaneous T-Cell Lymphoma
23.1 Case 23: Interpretation and Teaching
Reference
Chapter 24: Case 24: Active Myeloma Versus Schmorl's Node
24.1 Case 24: Interpretation and Teaching
Reference