BookMichael M. Vanyukov, editor.
Summary: The book illuminates the complex problems in genetic studies of substance use and addiction. It provides a comprehensive overview that fills the gap in the literature and points out future directions. The book includes three sections that apply to any complex traits and disorders, particularly psychological and psychiatric. The first section covers the traits and phenotypes that are the target of genetic research in substance use and addiction. Following this, the second section analyzes the methods and results of biometric genetic studies in this area. The third section reviews research in gene mapping and epigenetics. Genetics of Substance Use is a first-of-its-kind monograph that presents contemporary solutions and methods for a wide range of researchers and practitioners across disciplines.
Contents:
Substance use phenotyping
Substance use: disorders and continuous traits
Neurobiological systems in substance use
Psychological mechanisms of substance use
Biometric genetic studies in substance use
Twin studies
Family and adoption studies
Genomic studies in substance use
Gene mapping in complex disorders
Linkage and association studies
Epigenomic studies
Conclusions.