BookHilde Löfqvist.
Summary: This unique book is structured to give the reader a comprehensive view to understand the decline of hormones at midlife and the risks and benefits of evidence based hormonal treatments. The difference between bio-identical and synthetic hormones is shown. With this book the author intends to restore the trust of the mostly positive effects of hormone treatment during menopause. In this book effective hormone treatments that may be carried on for years are discussed. Those hormones may even prevent age related diseases (arthralgia, osteoporosis, cardiovascular diseases) if started at the right time frame directly after menopause, known as "window of opportunity". This book fills a gap for medical health providers and can be of benefit for all women searching evidence-based information and answers on hormone menopausal changes and treatments. The book provides the reader with case histories to show how different women are at the menopausal transition, and what the doctor has to consider in the choice of investigation and treatment.
Contents:
Intro
Foreword
Preface
About the Book
Contents
About the Author
Abbreviations
Chapter 1: Midlife Crisis During the Female Hormonal Transition, a Theme with Variations
1.1 How It Feels When Sex Hormones Are Declining
1.2 Resilience, the Ability to Cope with Difficulties
1.3 The Menopause Rating Scale (MRS)
1.4 Symptoms and Apprehensions
1.4.1 Hot Flushes
1.4.2 Sleeping Disorders
1.4.3 Mental Disorders
1.4.4 Sexual Problems
1.4.5 Physical Disorders
1.5 Cultural, Social and Ethnic Differences in Climacteric Symptoms and Treatments 1.6 Summary for the Health Professional
1.7 Summary for the Climacteric Woman
References
Chapter 2: Hormones
2.1 What Are Hormones?
2.2 The Sex Hormones
2.2.1 Oestrogens
2.2.2 Androgens
2.2.3 Progesterone
2.3 Hormonal Changes from the Conception Until the Postmenopausal Period
2.3.1 Conception
2.3.2 The Foetus
2.3.3 The Newborn Female Baby
2.3.4 Childhood
2.3.5 Prepuberty
2.3.6 Adolescence
2.3.7 The Mature Woman
2.3.8 The Menopausal Transition
2.3.9 Perimenopause
2.3.10 Menopause and the Postmenopause 2.4 Other Important Hormones, Which Decrease with Age
2.4.1 Growth Hormone
2.4.2 Melatonin
2.5 Hormones That Are Important All Through Life
2.5.1 Thyroid Hormones
2.5.2 Insulin
2.5.3 Leptin
2.5.4 Stress Hormones
2.6 Summary for the Health Professional
2.7 Summary for the Climacteric Woman
References
Chapter 3: Menopause Treatments with Hormones
3.1 Treatment of Age-Related Hormone Deficiency in Menopause
3.1.1 Oestradiol
3.1.1.1 Oral Oestradiol (a)
3.1.1.2 Transdermal Oestradiol (b)
3.1.1.3 Vaginal Oestradiol
3.1.2 Oestriol
3.1.3 Progesterone 3.1.3.1 Oral Micronized Progesterone
3.1.3.2 Vaginal Progesterone
3.1.3.3 Percutaneous Progesterone
3.1.4 Androgens
3.1.4.1 Testosterone
3.1.4.2 DHEA
3.1.5 Phytoestrogens
3.1.6 Progestogens
3.1.7 Conjugated Equine Estrogens
3.2 Hormonal Treatment of Gynaecological Disorders During the Menopausal Transition
3.2.1 Progestins as Monotherapy
3.2.2 Progestogens + Oestradiol/Ethinyloestradiol (OC, Oral Contraceptive Pills)
3.3 Advantages and Disadvantages in the Use of Different Menopausal Hormone Treatments
3.4 Hormonal Treatment in Menopause After Cancer 3.5 Summary for the Health Professional
3.6 Summary for the Climacteric Woman
References
Chapter 4: Treatment with Female Hormones: Rise and Fall, Confusion and Comeback
4.1 Positive Attitudes to Female Hormones Until 2002
4.2 The Impact of the WHI Study, Misinterpretation and Confusion
4.3 Protests Against Female Hormone Treatment
4.4 Body-Identical Hormone Replacement Therapy: The European Development
4.5 Bio-identical Hormone Replacement Therapy (BHRT): The American Development
4.6 The Renaissance of the Hormonal Treatment
4.7 Summary for the Health Professional
4.8 Summary for the Climacteric Woman.