Book[edited by] Richard A. McPherson, Matthew R. Pincus.
Summary: "This twenty-fourth edition marks more than 100 years since A Manual of Clinical Diagnosis, authored by James Campbell Todd, was introduced in 1908. In its current format as Henry's Clinical Diagnosis and Management by Laboratory Methods, this textbook remains the authoritative source of information for residents, students, and other trainees in the disciplines of clinical pathology and laboratory medicine, and for physicians and laboratory practitioners. The current edition continues the tradition of partnership between laboratory examinations and the formulation and confirmation of clinical diagnoses followed by monitoring of body functions, therapeutic drug levels, other results of medical treatments, and risk assessment for disease"--Publisher's description.
Contents:
Part 1: The clinical laboratory. General concepts and administrative issues
Optimizing laboratory workflow and performance
Preanalysis
Analysis: principles of instrumentation
Mass spectrometry and applications
Analysis: clinical laboratory automation
Point-of-care testing and physician office laboratories
Postanalysis: medical decision making
Interpreting laboratory results
Laboratory statistics
Quality control
Clinical laboratory informatics
Financial management
Ethics in laboratory medicine
Part 2: Clinical chemistry. Evaluation of renal function, water , electrolytes and acid-base function
Biochemical markers of bone metabolism
Carbohydrates
Lipids and dyslipoproteinemia
Cardiac injury, atherosclerosis, and thrombotic disease
Specific proteins
Clinical enzymology
Evaluation of liver function
Laboratory diagnosis of gastrointestinal and pancreatic disorders
Toxicology and therapeutic drug monitoring
Evaluation of endocrine function
Reproductive function and pregnancy
Vitamins and trace elements
Chemical basis for analyte assays and common interferences
Part 3: Urine and other body fluids. Basic examination of urine
Cerebrospinal, synovial, serous body fluids, and alternative specimens
Part 4: Hematology and transfusion medicine. Basic examination of blood and bone marrow
Hematopoiesis
Erythrocytic disorders
Leukocytic disorders
The flow cytometric evaluation for hematopoietic neoplasia
Immunohematology
Transfusion medicine
Hemapheresis
Tissue banking and progenitor cells
Part 5: Hemostasis and thrombosis. Coagulation and fibrinolysis
Platelet disorders and von willebrand disease
Laboratory approach to thrombotic risk
Antithrombotic therapy
Part 6: Immunology and immunopathology. Overview of the immune system and immunologic disorders
Immunoassays and immunochemistry
Laboratory evaluation of the cellular immune system
Laboratory evaluation of immunoglobulin function and humoral immunity
Mediators of inflammation: complement
Mediators of inflammation: cytokines and adhesion molecules
Human leukocyte antigen: the major histocompatibility complex of man
The major histocompatibility complex and disease
Immunodeficiency disorders
Clinical and laboratory evaluation of systemic autoimmune rheumatic diseases
Vasculitis
Organ-specific autoimmune diseases
Allergic diseases
Part 7: Medical microbiology. Medical bacteriology
In vitro testing of antimicrobial agents
Mycobacteria
Mycotic diseases
Spirochete infections
Chlamydial and mycoplasmal infections
Rickettsiae and other related intracellular bacteria
Viral infections
Medical parasitology
Specimen collection and handling for diagnosis of infectious diseases
Part 8: Molecular pathology. Introduction to molecular pathology
Molecular diagnostics: basic principles and techniques
Polymerase chain reaction and other nucleic acid amplification technology
Hybridization array technologies
Applications of cytogenetics in modern pathology
Molecular diagnosis of genetic diseases
Molecular genetics of neuro-psychiatric disorders: current research and perspectives
Identity testing: use of DNA analysis in parentage, forensic, and missing persons testing
Pharmacogenomics and personalized medicine
Part 9: Clinical pathology of cancer. Diagnosis and management of cancer using serologic and other body fluid markers
Oncoproteins and early tumor detection
Molecular diagnosis of hematopoietic neoplasms
Molecular genetic pathology of solid tumors
High-throughput genomic and proteomic technologies in the post-genomic era
Appendices. Physiologic solutions, buffers, acid-base indicators, standard reference materials, and temperature conversions
Desirable weights, body surface area, and body mass index
Approximations of total blood volume
Periodic table of elements
Si units
Common chimeric genes identified in human malignancies
Disease/organ panels.