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  • Book
    Alexzander A.A. Asea, Punit Kaur, editors.
    Summary: The book Heat Shock Proteins in Human Diseases provides the most comprehensive review on contemporary knowledge on the role of heat shock proteins (HSP) in various types of human diseases including cancer, cardiovascular disease, microbiology and inflammation. These diseases were specifically chosen due to their dismal prognosis, the survival benefit offered by the current standards do not greatly impact the overall survival statistics with the disease and are associated with toxicity. Using an integrative approach, the contributors provide a synopsis of the most current updates on the state of HSP in human diseases. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed articles that review present research activity on the role of heat shock proteins in human diseases and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Cardiovascular Diseases, Microbiology, Inflammation, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.

    Contents:
    Inter-Relationship Between the Inflammation and Heat Shock Protein in Cancer Development: A Possible Target for Diagnosis and Cancer Immunotherapy
    Chaperonin Hsp60 and Cancer Therapies
    Combined Thermotherapy and Heat Shock Protein Modulation for Tumor Treatment
    Small Molecule Inhibitors Targeting Heat Shock Response Pathways: Lessons from Clinical and Preclinical Studies in Cancer Therapeutics
    Multifaceted Roles of Heat Shock Factor 1 (HSF1) in Cancer
    Exploring the Role of Heat Shock Proteins in the Development of Gastric Cancer
    Heat Shock Proteins in Atrial Fibrillation
    Threading Microarrays into Novel Applications
    Regulation of Kaposi's Sarcoma-associated Herpesvirus Biology by Host Molecular Chaperones
    Role of Heat Shock Factors in Diseases and Immunity
    Heat Shock Proteins and Pain
    Regulates Cellular Senescence: Role of the DHRS2-MDM2-p53 Pathway
    Huntingtin Yeast Two-Hybrid Protein K (HYPK): An Intrinsically Unstructured Heat Shock Inducible Protein with diverse Cellular and Molecular Functions
    Roles of Heat Shock Proteins on Antigen Presentation
    Heat shock proteins mediate anastasis and plasticity of thermotolerant cells.
    Digital Access Springer 2021
  • Article
    Alho A, Jäättelä A, Lahdensuu M, Rokkanen P, Avikainen V, Karaharju E, Tervo T, Lepistö P.
    Ann Clin Res. 1977 Jun;9(3):157-63.
    The role of endogenous catecholamines in various clinical shock and stress states is reviewed; the effects, especially on the peripheral circulation, of catecholamine secretion are the same independent of the cause. Risks of using sympathomimetic agents in the treatment of shock are evaluated. A prolonged noradrenaline activity is to be expected in surgical stress states, e.g. multiple injuries, fat embolism syndrome, burns and infections; therapeutic approaches to minimize the sympathoadrenal activity are outlined.
    Digital Access Access Options