BookAlexzander A.A. Asea, Punit Kaur, editors.
Summary: The book Heat Shock Proteins in Human Diseases provides the most comprehensive review on contemporary knowledge on the role of heat shock proteins (HSP) in various types of human diseases including cancer, cardiovascular disease, microbiology and inflammation. These diseases were specifically chosen due to their dismal prognosis, the survival benefit offered by the current standards do not greatly impact the overall survival statistics with the disease and are associated with toxicity. Using an integrative approach, the contributors provide a synopsis of the most current updates on the state of HSP in human diseases. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed articles that review present research activity on the role of heat shock proteins in human diseases and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Cardiovascular Diseases, Microbiology, Inflammation, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
Contents:
Inter-Relationship Between the Inflammation and Heat Shock Protein in Cancer Development: A Possible Target for Diagnosis and Cancer Immunotherapy
Chaperonin Hsp60 and Cancer Therapies
Combined Thermotherapy and Heat Shock Protein Modulation for Tumor Treatment
Small Molecule Inhibitors Targeting Heat Shock Response Pathways: Lessons from Clinical and Preclinical Studies in Cancer Therapeutics
Multifaceted Roles of Heat Shock Factor 1 (HSF1) in Cancer
Exploring the Role of Heat Shock Proteins in the Development of Gastric Cancer
Heat Shock Proteins in Atrial Fibrillation
Threading Microarrays into Novel Applications
Regulation of Kaposi's Sarcoma-associated Herpesvirus Biology by Host Molecular Chaperones
Role of Heat Shock Factors in Diseases and Immunity
Heat Shock Proteins and Pain
Regulates Cellular Senescence: Role of the DHRS2-MDM2-p53 Pathway
Huntingtin Yeast Two-Hybrid Protein K (HYPK): An Intrinsically Unstructured Heat Shock Inducible Protein with diverse Cellular and Molecular Functions
Roles of Heat Shock Proteins on Antigen Presentation
Heat shock proteins mediate anastasis and plasticity of thermotolerant cells.