BookElisabetta Bugianesi, editor.
Summary: The goal of this book is to promote awareness of non-alcoholic fatty liver disease (NAFLD) - which is rapidly replacing viral hepatitis as the leading cause of chronic liver disease in Europe, North and South America and Asia - and to share the latest information on evolving approaches to diagnosis and treatment. The book offers a comprehensive overview of the current topics of interest in the field, and provides clinical guidance on NAFLD through a multidisciplinary approach based on the latest scientific understanding of this multisystemic disease, involving the expertise of specialists including hepatologists, diabetologists, and cardiologists. The respective contributions address various aspects, including the newly released international guidelines, novel diagnostic modalities, and new experimental drugs. The work will appeal to a broad readership, from residents in internal medicine to specialists.
Contents:
Introduction
Obesity and NAFLD: same problem? The burden of NAFLD worldwide
Histo-pathology of NAFLD
NAFLD and insulin resistance: a multisystemic
Etiopathogenesis of NAFLD: diet, gut and NASH
Etiopathogenesis of NAFLD: molecular mechanisms of fibrogenesis
The natural history of NAFLD: Environmental vs Genetic Risk Factors
NAFLD and endocrine disease: clinical implications
NAFLD and Cardiovascular Disease: clinical implications
NAFLD, Hepatocellular Carcinoma and extrahepatic cancers
NAFLD in children: implications for the future
Diagnostic algorithm for the identification of NAFLD in primary care
Non-Invasive diagnostic approach to NASH: Biological Markers
Non-Invasive diagnostic approach to NASH: Radiological Diagnostics
Dietary approach to NAFLD
Physical Activity in NAFLD: what and how much? Pharmacological Therapy of NASH
Bariatric Surgery and NASH: a feasible option? Liver transplantation and NASH
Unmet needs and future goals.