Bookby Brian A. Baldo, Nghia H. Pham.
Summary: The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships. New content expands to two areas of drug allergy that have recently experienced explosive growth: biological therapies and new targeted chemotherapies. Other new and expanded chapters address antimicrobials; drugs used in anesthesia and surgery; opioids; non-targeted anti-cancer drugs; vaccines; and newly understood reaction mechanisms. This new edition includes photographs of a wide variety of cutaneous manifestations that will be of use to other clinicians as well as allergists and dermatologists. In addition to its wide clinical emphasis, the book's mechanistic and structure-activity detail will provide valuable background for researchers and investigators in universities, medical research institutes, drug companies, and regulatory agencies. The second edition of Drug Allergy is an essential reference for practitioners across the medical disciplines from specialist clinicians, surgeons, GPs, residents, and medical students to nurses, pharmacists, dentists, and those taking undergraduate and graduate courses in the biomedical sciences.
Contents:
Ch. 1. Adverse reactions to drugs and drug allergy
Ch. 2. Classification and descriptions of allergic reactions to drugs
Ch. 3. Mechanisms of hypersensitivity
Ch. 4. Diagnosis of allergic reactions to drugs
Ch. 5. Beta-Lactam antibiotics
Ch. 6. Other antimicrobial drugs
Ch. 7. Drugs and other agents used in anesthesia and surgery
Ch. 8. Opioid analgesic drugs
Ch. 9. Nonsteroidal anti-inflammatory drugs
Ch. 10. Contrast media
Ch. 11. Corticosteroids
Ch. 12. Proton pump inhibitors
Ch. 13. Targeted drugs for cancer therapy. Approved monoclonal antibodies
Ch. 14. Non-targeted drugs for cancer therapy
Ch. 15. Other approved therapeutic monoclonal antibodies
Ch. 16. Other biologics
Ch. 17. Vaccines.