BookJörg Reichrath, editor.
Summary: The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and sunscreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV-exposure to minimize the risks of developing vitamin D deficiency and skin cancer.
Contents:
Section I: Introduction
Lessons learned from paleolithic models and evolution for human health: a snap shot on beneficial effects and risks of solar radiation
Section II: UV-induced cutaneous synthesis of vitamin D and the physiologic consequences (I)
Sunlight, UV-radiation, vitamin D and skin cancer: how much sunlight do we need?
Section III: Solar radiation, Vitamin D and human health
Vitamin D status and cancer incidence and mortality
Vitamin D receptors polymorphisms and cancer
On the relationship between sun exposure and all-cause mortality
Lindqvist PG (2020) Women with greater sun exposure habits seem to be healthier and to live longer. Are these results in contrast to other research? No
Section IV: Epidemiology of skin cancer
Epidemiology of skin cancer and UV radiation
update 2019
Solar UV exposure and mortality from skin tumors: an update
Solarium Use and Risk for Malignant Melanoma: many open questions,not the time to close the debate
Section V: Photocarcinogenesis of skin cancer
Molecular biology of basal and squamous cell carcinomas
Human papillomaviruses and skin cancer
The immune system and pathogenesis of melanoma and nonnmelanoma skin cancer
Section VI: The relevance of the vitamin D endocrine system for skin cancer
Protection from ultraviolet damage and photocarcinogenesis by vitamin D compounds
The role of classical and novel forms of vitamin D in the pathogenesis and progression of non-melanoma skin cancers
The Vitamin D Receptor as tumor suppressor in skin
Cancer prevention in skin and other tissues via cross-talk between vitamin D- and p53- signalling
Section VII: Prevention and Management of Skin Cancer
Sunscreens in the United States: Current Status and Future Outlook
A handful of sunscreen for whole body application
Sunlight, vitamin D and Xeroderma pigmentosum
Update: Solar UV-radiation, vitamin D and skin cancer surveillance in organ transplant recipients (O TRs)
Section VIII: UV-induced cutaneous synthesis of vitamin D and the physiologic consequences
II. promise and outlook
Ultraviolet exposure scenarios: balancing risks of erythema and cutaneous vitamin D synthesis
The Paleolithic nutrition model in relation to ultraviolet light and vitamin D
Index.