BookBusi Siddhardha, Madhu Dyavaiah, Asad Syed, editors.
Summary: "This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm formation. Due to the emergence of various microbial resistant strains, it is especially important to understand the prognosis for microbial infections, disease progression profiles, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the book presents a comparative analysis of various animal models to help readers understand microbial pathogenesis, host-pathogen interactions, anti-microbial drug discovery, anti-biofilm therapeutics, and treatment regimes. Given its scope, the book represents a valuable asset for microbiologists, biotechnologists, medical professionals, drug development researchers, and pharmacologists alike."-- Provided by publisher.
Contents:
Intro
Preface
Contents
Editors and Contributors
About the Editors
Contributors
1: Microbial Infections and Virulence Factors
1.1 Introduction
1.1.1 Colonization of Host Surfaces by Pathogenic Microorganisms
1.1.2 Initiation and Maintenance of Pathogens in Intracellular Lifestyle
1.1.3 Crossing of Host Barriers by Pathogens
1.2 Microbial Infections
1.2.1 Bacterial Infections
1.2.2 Fungal Infections
1.2.3 Viral Infections
1.3 Virulence Factors Associated with Microbial Infections
1.3.1 Extracellular Virulence Factors 1.3.2 Cell Associated Virulence Factors
1.4 Conclusion
References
2: Microbial Pathogenesis: Virus Pathogen-Host Interactions
2.1 Introduction
2.2 Historical Views of Host-Microbe Interactions
2.2.1 Fundamental Properties of Viruses
2.2.1.1 Principal Rules of Virus-Host Interactions
2.2.2 Host Defense Mechanisms
2.2.2.1 Defensive Host and Unwearied Pathogens
2.2.3 Different Types of Virus-Host Interactions
2.2.3.1 Transient Infections
2.2.3.2 Acute Infections
2.2.3.3 Latent Infections
2.2.3.4 Persistent Infections 2.2.4 Virus-Host Interactions
2.2.4.1 Virus-Host Interactions: Attachment and Entry
2.2.4.2 Virus-Host Interactions: Reprogramming the Metabolism
2.2.4.2.1 General Trends of Metabolic Changes
2.2.5 Virus-Host Interactions: Reprogramming the Changes in Structure and Function of Cell Organelles
2.2.6 Future Directions of Virus-Host-Pathogen Interactions
2.3 Conclusion
References
3: A Physical Insight of Biofilms
3.1 Introduction
3.2 Single Particle Tracking Method
3.3 Relevance of Physical Properties in Biofilms Formation
3.4 Branching Patterns 3.5 Recent Observations on Biofilms
References
4: A Review on Microbial Pathogenesis and Host Response
4.1 Introduction
4.1.1 Host-Microbe Relationship
4.1.1.1 Mutualism
4.1.1.2 Commensalism
4.1.1.3 Parasitism
4.2 Routes of Infection and Progression
4.2.1 Adhesion
4.2.2 Internalization
4.2.3 Colonization
4.2.4 Microbial Secretion System
4.3 Microbial Pathogenesis and Host Immune Response
4.3.1 Innate Immune Response
4.3.2 Adaptive or Specific Immune Responses
4.4 Conclusion
References 5: Role of Quorum Sensing in Microbial Infections and Biofilm Formation
5.1 Introduction
5.2 The Bacterial Chatter's
5.3 Quorum Sensing: The Bacterial Language
5.4 Biofilm Formation and Bacterial Infections Control by Quorum Sensing
5.5 Applications of Quorum Sensing in Biotechnology
5.6 Biofilm Matrix Composition and Architecture
5.6.1 Biofilm Matrix Composition
5.6.2 Biofilm Architecture
5.6.3 Biofilm Role in Human Infections
5.7 Applications of Biofilm in Biotechnology
5.8 Conclusion
References