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  • Book
    Davide Chiumello, editor.
    Summary: This book offers an essential guide to managing the most heatedly debated topics of practical interest in anesthesia and intensive care. It reviews the state of the art in issues concerning both intensive care medicine and anesthesia, such as antibiotic therapy in multidrug resistance infection, acute hepatic failure, weaning, ECMO, difficult airway in pediatric patients, goal directed fluid therapy, preoperative anesthesia evaluation and delirium. Written by leading experts and including updated references, it provides a comprehensive, easy-to-follow guide to anesthesia and intensive care. The book clearly explains complex topics, offering practicing clinicians valuable insights into the latest recommendations and evidence in the field while, at the same time, making it a vital resource for students new to the fields of anesthesia and intensive care.

    Contents:
    Intro
    Contents
    1: The Role of the Heart in Weaning Failure
    1.1 Weaning as an Intense Exercise
    1.2 The Diagnosis of Weaning Failure of Cardiovascular Origin
    1.3 Transthoracic Echocardiography
    1.4 Conclusions
    References
    2: MDR Infections in the ICU
    2.1 Infections and Resistance: The Problem Dimension
    2.2 Infections and Resistance: Definitions
    2.3 MDR Gram Positive
    2.3.1 MRSA
    2.3.2 Potential Role for the New Antibiotics
    2.3.3 VRE
    2.4 MDR Gram Negative
    2.4.1 ESBL-Producing Enterobacteriaceae
    2.4.2 AmpC-Producing Enterobacteriaceae 2.4.2.1 Carbapenem-Resistant Gram Negative
    2.4.3 XDR P. aeruginosa
    2.4.4 XDR A. baumannii
    2.4.5 KPC-Producing K. pneumoniae and Other Carbapenemase-Producing Enterobacteriaceae (CRE)
    2.5 Empiric Therapy
    2.6 Duration of Therapy
    2.7 Role of Additional Therapies in Gram-Negative MDR/XDR Bacteria Septic Shock
    2.8 Prevention and Control of MDR Infections in the ICU
    2.9 Antimicrobial Stewardship
    References
    3: The Diaphragmatic Dysfunction
    3.1 Introduction
    3.2 The Diaphragm
    3.3 Anatomy and Respiratory Function 3.4 Diaphragmatic Dysfunction and Fatigue
    3.4.1 Diaphragmatic Dysfunction
    3.5 Invasive Evaluation of Diaphragmatic Function
    3.6 Noninvasive Evaluation of Diaphragmatic Function: The Ultrasound
    3.7 Diaphragmatic Displacement
    3.7.1 Limits of the Technique
    3.8 Thickness and Thickening Fraction
    3.9 Conclusion
    References
    4: Neuromuscular Blocking Agents: Review on Agents (NMBA and Antagonists) and Monitoring
    4.1 Introduction
    4.2 Neuromuscular Blocking Agents (NMBAs): The Classification [5, 7, 8, 10, 16, 18] 4.2.1 Neuromuscular Junction and Basic Physiology of Neurotransmission [5, 15, 18, 19] (Fig. 4.1)
    4.3 Depolarizing Neuromuscular Blocking Agents: Succinylcholine (SCh) [7, 8, 10, 18, 19] (Fig. 4.2)
    4.3.1 Side Effects [7, 8, 18, 19]
    4.4 Nondepolarizing Neuromuscular Blocking Agents (NDNMBAs)
    4.4.1 Aminosteroidal NDNMBAs
    4.4.2 Benzylisoquinoline Derivatives
    4.5 Monitoring Neuromuscular Function in Anesthesia [5, 15, 16, 17, 20-22]
    4.5.1 Train of Four (TOF) [5, 15, 16, 22]
    4.5.2 Post-Tetanic Twitch Count (PTC) [5, 15, 22] 4.5.3 Double-Burst Stimulation (DBS) [5, 15]
    4.6 Neuromuscular Blockade Antagonization
    4.6.1 Acetylcholinesterase Inhibitors (ACEIs) [5, 7, 8, 17, 18]
    4.6.2 Sugammadex (SUG) [5, 7, 8, 17, 18, 31, 32]
    4.7 Future Perspectives [7, 8, 34-36]
    References
    5: Extracorporeal Circulation in Acute Respiratory Failure: High Flow Versus Low Flow
    5.1 Introduction
    5.2 General Principles of Treatment
    5.3 History
    5.4 Techniques
    5.4.1 Extracorporeal Membrane Oxygenation (ECMO)
    5.4.2 Extracorporeal CO2 Removal (ECCO2R)
    5.5 Indications and Contraindications
    Digital Access Springer 2020