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  • Book
    J. Robin Harris, Jon Marles-Wright, editors.
    Summary: This book follows on from Volume 83 in the SCBI series ("Macromolecular Protein Complexes"), and addresses several important topics (such as the Proteasome, Anaphase Promoting Complex, Ribosome and Apoptosome) that were not previously included, together with a number of additional exciting topics in this rapidly expanding field of study. Although the first SCBI Protein Complex book focused on soluble protein complexes, the second (Vol. 87)addressed Membrane Complexes, and the third (Vol. 88) put the spotlight on Viral Protein and Nucleoprotein Complexes, a number of membrane, virus and even fibrillar protein complexes have been be considered for inclusion in the present book. A further book is also under preparation that follows the same pattern, in an attempt to provide a thorough coverage of the subject. Chapter "Structure and Function of Roundabout Receptors" is available open access under a CC BY 4.0 license via

    Chapter 1. Introduction: Protein Oligomerization and the Formation of Macromolecular Assemblies,- Chapter 2. Antibody complexes
    Chapter 3. Unravelling ribosome function through structural studies
    Chapter 4. Competence Functions and mechanisms of the human ribosome-translocon complex
    Chapter 5. The Structures of Eukaryotic Transcription Pre-Initiation Complexes and Their Functional Implications
    Chapter 6. Regulation of Antiviral Innate Immunity Through APOBEC Ribonucleoprotein Complexes
    Chapter 7. Structure and Function of the AAA+ ATPase p97, a Key Player in Protein Homeostasis
    Chapter 8. Penicillin-Binding Proteins (PBPs) and bacterial cell wall elongation complexes
    Chapter 9. Structure and function of Roundabout receptors
    Chapter 10. Structure and function of molecular chaperones that govern immune peptide loading
    Chapter 11. Biology and Biochemistry of Bacterial Proteasomes
    Chapter 12. The Kai-protein clock
    keeping track of cyanobacteria's daily life
    Chapter 13. Frataxin Structure and Function
    Chapter 14. Crystallins and their complexes
    Chapter 15. Structure and Function of the TREX-2 Complex
    Chapter 16. Amyloid Oligomers, Protofibrils and Fibrils
    Chapter 17. CAD, a multienzymatic protein at the head of de novo pyrimidine biosynthesis
    Chapter 18. The Anaphase Promoting Complex/Cyclosome (APC/C): a versatile E3 ubiquitin ligase
    Chapter 19. TRiC/CCT Chaperonin: Structure and Function.
    Digital Access Springer 2019