Bookedited by Alexzander A.A. Asea, Punit Kaur.
Summary: The book Heat Shock Proteins in Neuroscience provides the most comprehensive review on contemporary knowledge on the role of HSP in signaling pathways relevant to a number of diseases. Using an integrative approach, the contributors provide a synopsis of novel mechanisms, signal transduction pathways. To enhance the ease of reading and comprehension, this book has been subdivided into various section including; Section I, reviews current progress on our understanding of Neurological Aspects of HSP; Section II, focuses on Aspects of HSP in Neurodegenerative Diseases and Disorders, Section III, emphasizes the importance of HSP in Multiple Sclerosis; Section IV, reviews critical Aspects of HSP in Alzheimer's Disease and Section V, gives a comprehensive update of the Development of HSP-Based Therapies for Neurological Disorders. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for starters and professionals in the fields of Neurology and Neurosciences, Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
Contents:
Section I: Neurological Aspects of HSP
Chapter 1. Hsp60 Friend and Foe of the Nervous System
Chapter 2. Role of Heat Shock Proteins in Brain Tumors
Chapter 3. Body Temperature Regulation Determines Immune Reactions and Species Longevity
Chapter 4. Interaction between Heat Shock Proteins and Components of the Plasminogen Activator System in the Central Nervous System
Chapter 5. Role of HSP70 in Plasticity and Mem
Chapter 6. Role of Heat Shock Proteins (HSP) in Neuroprotection for Ischemic Stroke
Section II: Aspects of HSP in Neurodegenerative Diseases and Disorders
Chapter 7. Dysregulation of Heat Shock Proteins in Neurodegenerative Diseases: Restorative Roles of Small Molecules and Natural Compounds
Chapter 8. Molecular Chaperones and Protein Quality Control System in the Canine Model of Brain Aging and Neurodegenerative Diseases
Chapter 9. Role of Hsp90 Interacting Molecular Chaperones on Tau And Ass Processing in Alzheimer's Disease
Section III: Aspects of HSP in Multiple Sclerosis
Chapter 10. Role of Hsp70 in Multiple Sclerosis: An Overview
Chapter 11. Protective Role of Glial Heat Shock Proteins in Amyotrophic Lateral Sclerosis
Section IV: Development of HSP-Based Therapies for Neurological Disorders
Chapter 12. Therapeutic Drugs and Natural Products: The Effect of Suppressing Hsps in Brain Tumors
Chapter 13. Can HSP Targeted Gene Therapy be a New Hope for Gliomas?
Chapter 14. Therapeutic Aspects of Heat Shock Proteins in Glioma: Cementing the Crevasses between Bench and Bedside
Chapter 15. Engineering Chaperones for Alzheimer's Disease: Insights from Drosophila Models
Chapter 16. Role of HSP in the Treatment of Internal Dıseases.