BookShanfa Lu, editor.
Summary: This is the first book on the genome of Salvia miltiorrhiza, summarizing the research advances in the molecular mapping, whole genome sequencing, chloroplast and mitochondria genomes, epigenetics, transcriptomics and functional genomics of this emerging model plant with great economic and medicinal value. It also describes its distribution, taxonomy and morphology and provides useful information on its cultivation and breeding. Further, it highlights the biosynthetic pathways of tanshinones and phenolic acids - two main classes of bioactive components produced in this plant species - and reviews and discusses the technology of hairy root induction, tissue culture and genetic transformation of S. miltiorrhiza. The book is a valuable resource for students, teachers and researchers in academia and industry interested in medicinal plants and pharmacy.
Contents:
Intro; Preface to the Series; Preface; Contents; Contributors; 1 Salvia miltiorrhiza: An Economically and Academically Important Medicinal Plant; Abstract; 1.1 Introduction; 1.2 Taxonomy; 1.3 Distribution; 1.4 Morphology; 1.5 Propagation; 1.6 Growth Requirements; 1.7 Chemical Constituents; 1.8 Medicinal Significance; 1.9 Academic Significance; 1.10 Conclusion; Acknowledgements; References; 2 Salvia miltiorrhiza Resources, Cultivation, and Breeding; Abstract; 2.1 Introduction; 2.2 Danshen Resources; 2.3 Danshen Distribution and Cultivation; 2.3.1 Wild and Cultivated Distribution 2.3.2 Cultivation Procedures2.3.3 Cultivation-Related Research Findings; 2.4 Danshen Breeding; 2.4.1 System and Bulk Selection; 2.4.2 Cross-breeding; 2.4.3 Polyploidy Breeding; 2.4.4 Space Mutation; 2.5 Perspectives; Acknowledgements; References; 3 Molecular Maps and Mapping of Genes and QTLs of Salvia miltiorrhiza; Abstract; 3.1 Introduction; 3.2 Molecular Linkage Map Construction; 3.2.1 Map Strategy and Mapping Populations; 3.2.2 F1 Genotyping, Data Analysis and Map Construction Method; 3.2.3 Genetic Linkage Map Construction of S. miltiorrhiza 3.2.3.1 The First Linkage Genetic Map and Another Map Based on Integration of Multiple Markers3.2.3.2 The Genomic SSR Linkage Genetic Map; 3.2.3.3 The High-Density Linkage Genetic Map; 3.3 Quantitative Trait Loci Analysis of Important Agronomic Traits in S. miltiorrhiza; 3.3.1 Quantitative Trait Loci (QTL) Mapping Method; 3.3.2 QTL Analysis for Phenolic Acid Content; 3.3.3 QTL Analysis for Root Yield; 3.4 Discussion; Acknowledgements; References; 4 The Genome of Salvia miltiorrhiza; Abstract; 4.1 Introduction; 4.2 The Sequencing and Assembly of S. miltiorrhiza Genome 4.2.1 Sequencing of the S. miltiorrhiza 99-3 Genome (Xu et al. 2016a)4.2.2 Genome Assembly of the S. miltiorrhiza; 4.2.3 Genome Annotation and Repeat Element Analysis; 4.2.4 Genome Family Evolution of S. miltiorrhiza; 4.2.5 Gene Clusters Related to Tanshinone Biosynthesis; 4.3 The Chloroplast Genome of S. miltiorrhiza; 4.4 The Full-Length Transcriptome Based on S. miltiorrhiza Genome; 4.4.1 Full-Length Transcriptome Analysis; 4.4.2 Identification of Alternatively Spliced Isoforms Using Full-Length Transcriptome Data; 4.5 Conclusion; Acknowledgements; References 5 The Chloroplast and Mitochondrial Genomes of Salvia miltiorrhizaAbstract; 5.1 Introduction; 5.2 Transcriptome of S. miltiorrhiza Chloroplasts; 5.3 Methylation of S. miltiorrhiza Plastome; 5.4 Basic Information for S. miltiorrhiza Mitochondrial Genome; 5.5 RNA Editing of S. miltiorrhiza Mitogenome; 5.6 Conclusion and Perspectives; Acknowledgements; References; 6 Salvia miltiorrhiza Epigenetics; Abstract; 6.1 Introduction; 6.2 miRNAs in S. miltiorrhiza; 6.2.1 miRNAs and Development of S. miltiorrhiza; 6.2.2 miRNAs Involved in Signal Transduction