Bookedited by Gabor Kovacs, Lois Salamonsen.
Summary: The last step in the IVF treatment cycle, embryo transfer, is also the process with the highest failure rate. No matter how good the laboratory technique is, a successful pregnancy will not be achieved without meticulous preparation of the uterus to accept the embryo. This book reviews the scientific evidence on endometrial receptivity, including histological, hormonal, biochemical, and immunological factors. Practical and concise, it supports gynecologists and embryologists to make evidence-based decisions that can influence the success rates of implantation and live births. Part of a series of books offering treatments and strategies for fertility and conception to optimize IVF outcomes, this volume is for all clinicians and embryologists working in reproductive medicine.
Contents:
Physiology of endometrial development through the cycle and implantation / Annabelle Brennan and Martha Hickey
Molecular and cellular basis of human embryo implantation / Guiying Nie and Eva Dimitriadis
Protein biomarkers of endometrial receptivity / Tracey A. Edgell
Genetic markers of endometrial receptivity (GMER) / Patricia Diaz-Gimeno and Juan A Garcia-Velasco
Effects of superovulation on the endometrium / Natalie Hannan and Jemma Evans
Screening the uterine microbiome prior to embryo transfer / Inmaculada Moreno and Carlos Simon
Estrogen and progesterone support in ART : optimizing implantation / Jamie Stanhiser and Steven L. Young
The role of hysteroscopy and endometrial scratch in improving endometrial receptivity / Yuval Or and Zeev Shoham
Fibroids and polyps : their effect on implantation / Beverley Vollenhoven and Sarah Hunt
Cleavage stage or blastocyst transfer : which is better? / Jason Kasraie
Dummy embryo transfer / Khaldoun Sharif and Gamal I Serour
Does the type of catheter used for embryo transfer matter? / Tia Hunjan, Shirin Khanjani and Stuart Lavery
Should all embryos be transferred in unstimulated cycles? / Nikoletta Panagiotopoulou and Siladitya Bhattacharya
Rest after embryo transfer is unhelpful / Giuseppe Botta and Gedis Grudzinska
Ectopic pregnancies : why do they happen? / R.R. Chodankar and Andrew Horne
The role on NK cells in implantation after IVF and treatment strategies / Norman Shreeve and Ashley Moffett
Sex and immune receptivity for embryo transfer / David J. Sharkey and Sarah A. Robertson
Immunotherapy/IVIG, prednisolone and intralipid in IVF / Ole Bjarne Christiansen and Kathinka Marie Nyborg
The role of heparin and aspirin to aid implantation / Luciano Nardo and Tarique Salman
Early pregnancy loss : causes and prevention / Shreeya Tewary and Jan J. Brosens
Is the endometrium in women with PCOS compromised? / Terhi T. Piltonen.