BookLars Kaestner, Peter Lipp, editors.
Summary: This book provides in depths information on different microscopy approaches and supplies the reader with methods how to untangle highly complex processes involved in physiological and pathophysiological cardiac signaling. Microscopy approaches have established themselves as the quasi gold standard that enables us to appreciate the underlying mechanisms of physiological and pathophysiological cardiac signaling. This book presents the most important microscopy techniques from the level of individual molecule e.g. Forster-Resonance Energy Transfer (FRET), up to cellular and tissue imaging, e.g. electron microscopy (TEM) or light sheet microscopy. The book is intended for graduate students and postdocs in cardiovascular research, imaging and cell biology, pre-clinical and clinical researchers in cardiovascular sciences as well as decision makers of the pharmaceutical industry.
Contents:
Studying structure and function of the heart cells using scanning ion conductance microscopy
Optical sectioning microscopy at 'temporal super-resolution'
Quantitative super-resolution microscopy of cardiomyocytes
Caged compounds : applications in cardiac muscle research
Optogenetic tools in the microscopy of cardiac excitation-contraction coupling
Electron microscopy.