BookShailza Singh, editor.
Summary: The book uses an integrated approach to predict the behavior of various biological interactions. It further discusses how synthetic biology gathers the information about various systems, in order to either devise an entirely new system, or, to modulate existing systems. The book also tackles the concept of modularity, where biological systems are visualized in terms of their parts. The chapters discuss how the principles of engineering are being used in biomedical sciences, to design biological circuits that can harbor multiple inputs and generate multiple outputs; to create genetic networks and control gene activity, in order to generate a desired response. The book aims to help the readers develop an array of biological parts, and to use these parts to develop synthetic circuits that can be assembled like electronic circuits. The ultimate aim of the book will be to serve as an amalgamation of key ideas of how judiciously synthetic biology could be exploited in therapeutic device and delivery mechanism.
Contents:
Chapter 1. Integrated Systems and Chemical biology approaches for targeted therapies
Chapter 2. Application of bioengineering in revamping human health
Chapter 3. Integrative Omics for Interactomes
Chapter 4. Studying parasite gene function and interaction through ribozymes and riboswitches design mechanism
Chapter 5. Genome microbiology for Synthetic applications
Chapter 6. Medicinal Application of Synthetic Biology
Chapter 7. Computational tools for applying multi-level models to Synthetic Biology
Chapter 8. Computational techniques for a comprehensive understanding of different genotype-phenotype factors in biological systems and their applications
Chapter 9. Alignment-free analyses of nucleic acid sequences using graphical representation
Chapter 10. Modern Approaches in Synthetic Biology: Genome Editing, Quorum Sensing and Microbiome Engineering
Chapter 11. Synthetic Probes, their applications & designing
Chapter 12. Omics Based Nanomedicine
Chapter 13. Characterization of plant genetic modifications using Next Generation Sequencing.