BookHirak Ranjan Dash, Pankaj Shrivastava, Braja Kishore Mohapatra, Surajit Das, editors.
Summary: This book describes the basics and various applications of DNA fingerprinting, including in actual case studies. The book is divided in four modules; Module 1: Basics of DNA Fingerprinting, Module 2: Applications of DNA Fingerprinting, Module 3: DNA Fingerprinting: Case Studies, and Module 4: Future of DNA Fingerprinting. Each module consists of 4 to 5 chapters, written by reputed researchers, academics and forensic scientists from around the globe. The respective chapters cover e.g. related fields, the tools and techniques used, various genotyping kits, real-world case studies, ancient DNA and wild life forensics, molecular diagnosis of human diseases, legal aspects, microbial forensics and the economics of the DNA fingerprinting technique. The book offers a practical guide for professionals, graduate and post-graduate students in the fields of Forensic Science, Medicine, Genetics, Anthropology, Microbiology, and Zoology. It also serves as a useful reference resource, summarizing major technological advances in the field of DNA fingerprinting, the problems faced in this field of science and possible new solutions to these problems. Presently, DNA fingerprinting is utilized in solving the majority of criminal cases; as such, the book is also helpful for investigating agencies, as it includes representative case studies.
Contents:
Module 1_ Basics of DNA Fingerprinting: Chapter 1. DNA Fingerprinting technique: Discovery, Advancements and Milestones
Chapter 2. Genetic Basis of DNA Fingerprinting in Humans
Chapter 3. Comparative Account of the DNA Fingerprinting Techniques: RFLP, STR Typing and NGS
Module 2_ DNA Fingerprinting: Tools and Techniques:
Chapter 4. Techniques involved in DNA Fingerprinting: Isolation, Quantification, PCR, Genotyping and Analysis
Chapter 5. STR Typing and available Kits
Chapter 6. In-silico techniques for analysis of genetic variation among individuals
Chapter 7. Statistical tools and techniques in interpretation of DNA sequencing results
Chapter 8. DNA fingerprinting with homologous multilocus probes and search for DNA markers
Module 3_ Applications of Genetic Fingerprinting:
Chapter 9. Analysis of Ancient DNA
Chapter 10. Wild Life Forensics
Chapter 11. Molecular Diagnosis of Human Genetic Diseases: Application of Genetic Fingerprinting
Chapter 12. Precautions and Recommendations for DNA fingerprinting for forensic applications
Chapter 13. Legal aspects of DNA fingerprinting
Module 4_ DNA Fingerprinting: Case Studies: Chapter 14. Autosomal DNA Typing: Case Studies
Chapter 15. Y-chromosome testing and case studies
Chapter 16. Mitochondrial DNA typing with case studies
Chapter 17. X-chromosome Analysis and Case Studies
Chapter 18 SNP analysis and Case Studies.