BookDirk Haller, editor.
Summary: The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.
Contents:
Introduction : Intestinal microbiome in health and disease
Composition and function of the gut microbiome
Microbiome and early life
Molecular microbiome analysis
Evolutionary perspectives on the human gut microbiome
Microbiome and diet
Microbiome and gut immunity : the epithelium
Microbiome and gut immunity : innate immune cells
Microbiome and gut immunity : T cells
Microbiome and gut immunity : B cells
Microbiome and diseases : inflammatory bowel diseases
Microbiome and diseases : allergy
Microbiome and disesases : graft-versus-host disease
Microbiome and diseases : pathogen infection
Microbiome and diseases : colorectal cancer
Microbiome and diseases : metabolic disorders
Microbiome and diseases : hepatic disorders
Microbiome and diseases : neurological disorders
Clinical implementation of high-throughput sequencing
Fecal transplantation
Gnotobiology.