BookAmritpal Singh Saroya, Jaswinder Singh.
Summary: "Natural Products have always played a pivotal role as sources for drug lead compounds. This book is aimed at providing inside purview of the scope of natural products (including herbal and marine) in the possible treatment of neurological disorders. The book explains pre-clinical neuropharmacological investigations done on herbs including Bacopa monnieri, Hypericum perforatum, Passiflora incarnata, Scutellaria baicalensis and Piper methysticum. It provides a comprehensive overview of the role of phytoconstituents like huperzine, curcumin, Salvinorin A, bioflavonoids, sulforaphane, tanshinone IIA, tetramethylpyrazine, tetrahydrocannabinol, and cannabidiol in the treatment of neurological disorders. The book provides a modern concept of herbal medications, neuropharmacology of marine bioactive products and Ayurvedic formulations, herbal drugs with abuse potential and neurotoxic mycotoxins."-- Provided by publisher.
Contents:
1. Introduction to Herbal Medicine
2. Medicinal Herbs Used in Herbal Medicine for Neurological Disorders
3. Neuropharmacology of Genus Hypericum. Hypericin and Hyperforin
4. Neuropharmacology of Lavender, Rosemary and Salvia
5. Neuropharmacology of Passiflora Genus
6. Neuropharmacology of Scutellaria baicalensis Georgi
7. Piper methysticum G. Forst: a Potent Antianxiety Agent
8. Neuropharmacology of Melissa officinalis L.
9. Neuropharmacology of Chamomiles
10. Neuropharmacology of Bacopa monnieri with Reference to Bacosides
11. Neuropharmacology of Acorus calamus L.
12. Neuropharmacology of Celastrus paniculatus Willd.
13. Phytopharmacology of Indian Nootropic Convolvulus pluricaulis
14. Neuropharmacology of Rhodiola rosea L.
15. Neuropharmacology of Salvia miltiorrhiza Bunge (Danshen)
16. Neuropharmacology of Withania somnifera Dunal.
17. Neuropharmacology of Nardostachys jatamansi DC.
18. Neuropharmacology of Nutritional Supplements
19. Neuropharmacology of Valeriana Genus
20. Neuropharmacology of Curcumin. Intro; Contents; About the Authors; 1: Introduction toHerbal Medicine; 1.1 Some Basic Definitions; 1.2 History ofHerbal Medicine; 1.3 Renaissance ofHerbal Medicine; 1.4 Herbal Glossary; 2: Medicinal Herbs Used inHerbal Medicine forNeurological Disorders; 2.1 Albizia julibrissin Baker (Fabaceae); 2.2 Acorus gramineus Sol. Aiton (Acoraceae); 2.3 Acorus tatarinowii Schott (Acoraceae); 2.4 Amphilophium crucigerum (L.) L.G. Lohmann (Bignoniaceae); 2.5 Galphimia glauca Cav. (Malpighiaceae); 2.6 Hypoxis hemerocallidea Fisch. & C.A. Mey. (Hypoxidaceae) 2.7 Litsea glaucescens Kunth (Lauraceae)2.8 Leonurus sibiricus L. (Lamiaceae); 2.9 Melissa officinalis L. (Lamiaceae); 2.10 Nepeta cataria L. (Lamiaceae); 2.11 Nepeta hindostana (Roth) Haines (Lamiaceae); 2.12 Petiveria alliacea L.; 2.13 Salvia guaranitica St. Hil. (Lamiaceae); 2.14 Sceletium tortuosum (L.) N.E. Brown (Aizoaceae); 2.15 Sorbus alnifolia (Sieb. et Zucc.) K. Koch (Rosaceae); 2.16 Stereospermum kunthianum Cham. (Bignoniaceae); 2.17 Tilia tomentosa Moench (Tiliaceae); 2.18 Verbena officinalis L. (Verbenaceae); References 3.13.3 Hypericum andObsessive-Compulsive Disorder (OCD)3.13.4 Comparative Trials withSynthetic Drugs; 3.13.4.1 Hypericum Extract vs Maprotiline; 3.13.4.2 Hypericum Extract Versus Imipramine; 3.13.4.3 Hypericum Extract Versus Amitriptyline; 3.13.4.4 Hypericum Extract Versus Fluoxetine; 3.13.4.5 Hypericum Extract Versus Sertraline; 3.13.4.6 Hypericum Extract Versus Citalopram; 3.13.4.7 Hypericum Extract Versus Paroxetine; 3.14 Neuropharmacology ofOther Hypericum Species; 3.14.1 Hypericum calycinum L.; 3.14.2 Hypericum caprifoliatum Cham. & Schltdl. 3.6.1.5 Neuroprotective Activity3.7 Neuropharmacology ofHypericin; 3.7.1 Non-clinical; 3.7.2 Clinical; 3.8 Neuropharmacology ofPseudohypericin; 3.9 Neuropharmacology ofH. perforatum Xanthones; 3.10 Neuropharmacology ofH. perforatum Flavonoids; 3.11 Neuropharmacology ofHyperforin; 3.11.1 Non-clinical; 3.11.2 Clinical; 3.12 Neuropharmacology ofAdhyperforin; 3.13 Clinical Pharmacology ofH. perforatum Extract; 3.13.1 Clinical Trials inDepression; 3.13.1.1 Mild toModerate Depression; 3.13.1.2 Severe Major Depression; 3.13.2 Hypericum andSeasonal Affective Disorder (SAD) 3: Neuropharmacology ofGenus Hypericum: Hypericin andHyperforin3.1 Hypericum perforatum Linn. (Guttiferae); 3.2 Habitat; 3.3 Botany; 3.4 Traditional Use inTreatment ofDiseases oftheNervous System; 3.5 Chemistry; 3.5.1 Napthodianthrones; 3.5.2 Acylphloroglucinols; 3.5.3 Flavonoids; 3.5.4 Flavanols; 3.5.5 Xanthones andSterols (Mathis andOurisson 1964); 3.5.6 Terpenoids; 3.6 Neuropharmacology ofH. perforatum Extract; 3.6.1 Non-clinical Studies; 3.6.1.1 Antidepressant Activity; 3.6.1.2 Anxiolytic Activity; 3.6.1.3 Anti-dementia Activity; 3.6.1.4 Antistress Activity