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  • Book
    John P. Neoptolemos, Raul Urrutia, James L. Abbruzzese, Markus W. Büchler, editors.
    Summary: In organizing the second edition of this renowned Handbook, Dr. Neoptolemos and his co-editors have produced and updated a revised edition to the distinguished Major Reference Work devoted to pancreatic cancer. Like its preceding edition, the second edition continues to have a widespread appeal among clinicians, pathologists and basic scientists, who are now struggling to understand this complex and rapidly expanding field. Because of the recent and vast growth in both the clinical and scientific research being done in pancreatic cancer, (there is currently an unprecedented investment by academia and industry in this field), each research's knowledge of other specialty areas outside his or her own is often quite limited. The aim of the new edition is to place the tangible advances, including new developments in surgical approaches with regards to resection techniques, the state of laparoscopic approaches, the growing impact of surgical approaches in the management of recurrent pancreatic cancer, controversies in the management of IMPN as the precursor lesion for PDAC and others - readily at hand. The second edition focuses on advances that will not become dated, and the editors have chosen authors, who are the very best in each area.

    Section: The Nature of Pancreatic Cancer
    Cell Cycle Machinery and Its Alterations in Pancreatic Cancer
    Animal modelling of Pancreatitis-to-Cancer Progression
    Stromal Inflammation in Pancreatic Cancer: Mechanisms and Translational Applications
    Familial Pancreatic Cancer
    Section: Clinical Management of Pancreatic Cancer
    Therapeutic Endoscopy in the Management of Pancreatic Cancer
    Controversies in Pathology Reporting and Staging
    Staging and Postoperative Outcomes Using the International Study Group of Pancreatic Surgery (ISGPS) Classifications
    Borderline Respectable Pancreatic Cancer
    New Japanese Classification of Pancreatic Cancer
    Arterial Resection in Pancreatic Cancer
    Treatment of Recurrent Pancreatic Cancer After Surgery
    Neoadjuvant Chemotherapy in Pancreatic Cancer
    Differential Therapy Based on Tumor Heterogeneity in Pancreatic Cancer
    Neoadjuvant Chemoradiation for Operable Pancreatic Cancer: the Importance of Local Disease Control
    Section: New Directions
    Development of Novel Therapeutic Response Biomarkers
    Clinical Applications of Genomics and Proteomics in Pancreatic Cancer
    Approaching Pancreatic Cancer Phenotypes via Metabolomics
    Circulating Tumour Cells
    Cancer Exosomes for Early Pancreatic Cancer Diagnosis and Role Metastasis
    Metabolism in Pancreatic Cancer
    Secondary Screening for Inherited Pancreatic Ductal Adenocarcinoma
    Role of Radiotherapy in Locally Advanced Pancreatic Cancer
    Evolution of Pancreatic Cancer Surgery
    Multiparameter Modalities for the Study of Patients in the Setting of Individualized Medicine
    Epigenetic Pharmacology
    Precision Medicine Based on Next Generation Sequencing and Master Controllers.
    Digital Access Springer 2018