BookMarta Lado, editor.
Summary: This current manual gives an overview to management of Ebola Virus Disease outbreaks from a practical point of view. It gives an introduction to the topic, reviews the history and previous outbreaks of Ebola virus disease and gives insight to clinical features of the disease. The major part of the book presents ways of response including screening, isolation and personal protection equipment as well as waste management during disease outbreaks. New therapies and experimental drugs are discussed in further detail. The last part of the volume deals with all aspects of diagnostics and practical laboratory handling of Ebola virus. Dr. Marta Lado is the clinical lead of the King's Sierra Leone Partnership in country team. She brings together a group of authors aggregating both well-grounded basic knowledge on Ebola virus as well as deep experience with Ebola Virus Disease in the field.
Contents:
EVD INTRODUCTION
Virology and VHF diseases: Ebola, Marbung, Lassa.-History of previous outbreaks
Sources of the infection, ways of transmission
CLINICAL FEATURES AND CASE DEFINITION
Clinical features: incubation period, clinical presentation and post Ebola syndrome
RESPONSE TO EVD OUTBREAK
Screening of suspected cases in a referral Hospital: variability of the case definition adapted to the outbreak. Screening forms and Standard precautions
Isolation Unit: how to set up and construct a holding unit in a hospital and satellite clinics
Personal protection equipment (PPE) and Infection prevention and control (IPC) measures
Waste management and cleaning/disinfection
Safe Medical Burials: practical and cultural implications
EVD MANAGEMENT
Symptomatic, supportive treatment- differences between treatment in the field and high resources settings (Europe, US)
Special populations: pregnancy and pediatrics
Controversies with invasive therapies: dialysis, ventilation
New therapies, Experimental drugs (Zmapp, Favipiravir, convalescent serum, etc) and vaccines
DIAGNOSTICS EVD
Rapid tests for EVD
Laboratory: RT-PCR, serology and Ag determination.