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  • Book
    Marta Lado, editor.
    Summary: This current manual gives an overview to management of Ebola Virus Disease outbreaks from a practical point of view. It gives an introduction to the topic, reviews the history and previous outbreaks of Ebola virus disease and gives insight to clinical features of the disease. The major part of the book presents ways of response including screening, isolation and personal protection equipment as well as waste management during disease outbreaks. New therapies and experimental drugs are discussed in further detail. The last part of the volume deals with all aspects of diagnostics and practical laboratory handling of Ebola virus. Dr. Marta Lado is the clinical lead of the King's Sierra Leone Partnership in country team. She brings together a group of authors aggregating both well-grounded basic knowledge on Ebola virus as well as deep experience with Ebola Virus Disease in the field.

    Contents:
    EVD INTRODUCTION
    Virology and VHF diseases: Ebola, Marbung, Lassa.-History of previous outbreaks
    Sources of the infection, ways of transmission
    CLINICAL FEATURES AND CASE DEFINITION
    Clinical features: incubation period, clinical presentation and post Ebola syndrome
    RESPONSE TO EVD OUTBREAK
    Screening of suspected cases in a referral Hospital: variability of the case definition adapted to the outbreak. Screening forms and Standard precautions
    Isolation Unit: how to set up and construct a holding unit in a hospital and satellite clinics
    Personal protection equipment (PPE) and Infection prevention and control (IPC) measures
    Waste management and cleaning/disinfection
    Safe Medical Burials: practical and cultural implications
    EVD MANAGEMENT
    Symptomatic, supportive treatment- differences between treatment in the field and high resources settings (Europe, US)
    Special populations: pregnancy and pediatrics
    Controversies with invasive therapies: dialysis, ventilation
    New therapies, Experimental drugs (Zmapp, Favipiravir, convalescent serum, etc) and vaccines
    DIAGNOSTICS EVD
    Rapid tests for EVD
    Laboratory: RT-PCR, serology and Ag determination.
    Digital Access Springer 2018