BookPablo Bertrand, Ignacio Sánchez, editors.
Summary: This book is a comprehensive and authoritative textbook on pediatric pulmonology. Edited by Pablo Bertrand and Ignacio Sánchez, renowned academics and pediatricians from the Pontifical Catholic University of Chile, it encompasses five sections and 74 chapters, presenting and discussing the most important topics related to pediatric respiratory diseases. Written and presented in a simple and didactic format, it intends to that ease learning and settlement of doubts in pediatric respiratory diseases. The reader is naturally introduced into the physiology, diagnosis, syndromes, diseases and the treatment associated to the respiratory pathologies affecting children. The chapters within this book includes algorithms for the treatment of syndromes and updated treatment proposals grounded on evidence-based medicine for more than 50 pulmonary diseases of pediatric importance. Pediatric Respiratory Diseases - A Comprehensive Textbook is an essential material for the proper clinical approach of respiratory diseases in children. It is intended for all interns, residents and fellows with interest in pediatric pulmonary medicine, as well as to physicians, general practitioners, pediatricians and pulmonologist who face pediatric respiratory disorders on their clinical practice.
Contents:
Intro
Contents
Contributors
1: History of Specialist Training in Respiratory Diseases
Introduction
The Situation in South America
Sources
2: Development of the Respiratory System
Introduction
Stages in Lung Development
Development of Bronchial Circulation
Respiratory Mechanics
Lung Weight/Body Weight and Lung Volume/Body Weight Ratios
Genetic Control of Lung Development
Factors That Influence Lung Development
Conclusion
Sources
3: Physiological Basis of the Respiratory System
Respiratory Mechanics
Airway Resistance Pulmonary Ventilation
Alterations in Pulmonary Ventilation
Alveolar Hypoventilation
Alveolar Hyperventilation
Pulmonary Circulation
The Ventilation/Perfusion Ratio
Respiratory Gases in the Blood
Sources
4: Clinical History and Physical Examination of the Respiratory System
Anamnesis
Physical Examination
Inspection
Palpation
Percussion
Auscultation
Wheezing
Crackles
Stridor
Grunting
Pleural Friction Rub
Sources
5: Physiological Evolution of Sleep
Introduction
History and Anamnesis
Age and Development
The Fetal Stage Premature Newborns
Newborns
Infants
Preschool Children and Older Infants (1-3 Years of Age)
Schoolchildren and Neuronal Plasticity
Adolescents
Risk Factors and Academic Performance
Specific Sleep-Associated Symptoms
Sources
6: Immunological Defense Mechanisms of the Respiratory System
Organization of the Respiratory Immune System
Immune Induction in the Lung
Innate Immunity
Adaptive Immunity
Immune Responses to Respiratory Infections
Immunology of Acute Alveolar Damage and Tissue Repair
The Microbiome
Sources 7: New Frontiers in Research on the Respiratory System
Cystic Fibrosis as a Model for Dealing with Chronic Lung Disease
Novel Strategies for Current Objectives
Gene Therapy
Small Molecules
Introduction to Complex Mutations
The Challenge: How Can We Know It Works?
The Problem: Delicate Secondary Effects Associated with Longevity
Selection of Resistant Organisms
Allergies to Antibiotics
Chronic Renal Insufficiency
Chronic Lung Disease Crises or Attacks: Lessons for a Long-Term Response
Pulmonary Attacks in Cystic Fibrosis
Pulmonary Attacks in Asthma Genetically Associated Diseases and Their Close Systemic Relationship: Ciliopathy
Learning from Follow-Up Studies on Chronic Lung Diseases
Beyond Tucson: Patterns of Wheezing in Preschool Children
Improved Phenotyping
The Microenvironment of the Airway and Development of Respiratory Diseases: The Microbiome
The Importance of the Microbiome in Healthy Children
The Microbiome in Early Wheezing Disorders
The Microbiome and Cystic Fibrosis
Is Clinical Pediatric Pneumology Dead?
Sources
8: Evaluation of Pulmonary Function in Infants and Preschool Children