BookErika Ruiz-Garcia, Horacio Astudillo-de la Vega, editors.
Summary: "This book presents concise chapters written by internationally respected experts on various important aspects of translational cancer genomics, offering a comprehensive overview of the onco-omics applications in the new era of cancer personal genomics research field. Being a complex disease that affects millions of people worldwide, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. In the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient's specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and even more, considering the immune system, the metabolism and in the near future the microbiome, all areas nowadays related in the prognosis and treatment of cancer patients. These contributions are either critical reviews or clinical and basic research reports. The topics discussed here include evidence-based medicine and provides useful information on translational cancer research to clinicians and biomedical scientists in order to offer another vision of cancer origin beyond the traditional causes or the oncogenic maintenance concept proposed by the oncogene addiction theory"--Publisher's description.
Contents:
Pharmaco-geno-proteo-metabolomics and translational research in cancer / Edith A. Fernández-Figueroa, Saul Lino-Silva, Jorge E. Peña-Velasco, Claudia Rangel-Escareño
Next generation sequencing (NGS): a revolutionary technology in pharmacogenomics and personalized medicine in cancer / Stefania Morganti, Paolo Tarantino, Emanuela Ferraro, Paolo D’Amico, Bruno Achutti Duso, Giuseppe Curigliano
Pharmaco-epigenomics: on the road of translation medicine / César López-Camarillo, Dolores Gallardo-Rincón, María Elizbeth Álvarez-Sánchez, Laurence A. Marchat
Design and implementing pharmacogenomics study in cancer / María Luisa Romero Lagunes, Francisco Emilio Vera Badillo
Onco-omics approaches and applications in clinical trials for cancer patients / Juan-Manuel Hernandez-Martinez, Roberto Sánchez-Reyes, J. G. De la Garza-Salazar, Oscar Arrieta
Issues and ethical considerations in pharmaco-oncogenomics / Gilberto Morgan
Pharma-oncogenomics in the era of personal genomics: a quick guide to online resources and tools / Rohan P. Joshi, David F. Steiner, Eric Q. Konnick, Carlos J. Suarez
Immuno-oncology in the era of personalized medicine / William R. Gwin III, Mary L. Disis, Erika Ruiz-Garcia
CAR-T cell and personalized medicine / Marlid Cruz-Ramos, Jesús García-Foncillas
Oncobiome at the forefront of a novel molecular mechanism to understand the microbiome and cancer / H. Astudillo-de la Vega, O. Alonso-Luna, J. Ali-Pérez, C. López-Camarillo, E. Ruiz-Garcia
Nutrition, cancer and personalized medicine / Jóse Ali Flores-Pérez, Fabiola de la Rosa Oliva, Yacab Argenes, Abelardo Meneses-Garcia.