BookAri J. Isaacson, Sandeep Bagla, Mathew C. Raynor, Hyeon Yu, editors.
Summary: This book comprehensively covers prostatic artery embolization (PAE) in interventional radiology (IR). PAE is a recently developed procedure primarily for the treatment of benign prostatic hyperplasia (BPH). BPH is an extremely common problem, affecting the urination of about half of men over the age of 50. PAE is a minimally invasive IR procedure that improves urinary symptoms secondary to BPH and, unlike most available BPH treatments, carries very little risk of compromising sexual function. It should be noted, however, that PAE is known to be a very difficult procedure due to the variations in pelvic arterial anatomy and small diameter of the target vessels. Because of the inherent challenge, interventional radiologists need resources to learn how to perform PAE, so they can add this exciting new procedure to their practice. This comprehensive, yet compact, text covers everything from patient evaluation, through procedure, and finally how to deal with failure or repeat procedures. Expert authors who are responsible for more than a third of PAEs performed in the United States include best practices and detailed steps for performing PAE, with potential pitfalls and related issues considered. Readers should come away from reading the text feeling confident in being able to provide PAE to their patients, whether it be for BPH, hemorrhage, or hematuria. This is an ideal guide for interventional radiologists hoping to learn or improve their skills for PAE.
Contents:
Anticholinergics/M3 AntagonistsMechanism of Action; Summary of Evidence; Side Effects and Pharmacodynamics; Beta-3-Agonists; Mechanism of Action; Efficacy; Side Effects; Medication Combinations; Alpha-Blockers and 5[alpha]-Reductase Inhibitors; Combination of [alpha]-Adrenergic Blockers and Antimuscarinic Medication; References;
Chapter 4: Indications for Surgical Management of Benign Prostatic Hyperplasia; Introduction; Transurethral Resection of the Prostate (TURP) (Fig. 4.1); Efficacy; Complications; Photoselective Vaporization of the Prostate (PVP) (Fig. 4.2); Efficacy; Complications Intro; Preface; Contents; Contributors;
Chapter 1: The Prostate and Benign Prostatic Hyperplasia; Normal Prostate Anatomy; Embryonic Development (Fig. 1.1); Relationships within the Pelvis (Fig. 1.2); Internal Prostate Anatomy (Fig. 1.3a, b); Normal Prostate Physiology; Function of the Prostate; Hormonal Control; Benign Prostatic Hyperplasia; Epidemiology; Pathophysiology; Clinical Features; References;
Chapter 2: Diagnosis of Benign Prostatic Hyperplasia; Introduction; Lower Urinary Tract Symptoms (Table 2.1); History; Physical Exam; Objective Questionnaires Regarding BPH Symptoms In-Office Objective BPH StudiesPressure-Flow Studies; Cystourethroscopy; Imaging Studies; References;
Chapter 3: Medical Management of Benign Prostatic Hyperplasia; Indications for Medical Management; Alpha-Adrenergic Receptor Blockers; Mechanism of Action; Nonspecific Versus Specific Alpha-Blockers; Summary of Evidence; Terazosin; Doxazosin; Alfuzosin; Tamsulosin; Silodosin; Side Effects; 5-Alpha-Reductase Inhibitors; Mechanism of Action; Summary of Evidence; Finasteride; Dutasteride; Side Effects; Phosphodiesterase-5 Inhibitors; Mechanism of Action; Summary of Evidence; Side Effects The Rezūm® System (NxThera Inc., Maple Grove, MN, USA) (Fig. 4.3)Efficacy; Complications; The UroLift® System (NeoTract, Pleasanton, CA, USA) (Fig. 4.4); Operative Technique; Efficacy; Complications; Surgical Treatment for Larger Prostates; Simple Prostatectomy; Open Prostatectomy; Robotic/Laparoscopic Prostatectomy; Efficacy; Complications; Holmium Laser Enucleation of the Prostate (HoLEP); Operative Technique; Efficacy; Complications; References;
Chapter 5: Imaging of the Prostate; Imaging Overview; Ultrasound; Computed Tomography; Magnetic Resonance Imaging; References
Chapter 6: Preclinical and Clinical Evidence for Prostatic Artery EmbolizationBackground; Preclinical Animal Studies; Clinical Evidence; Summary; Conclusion; Future Directions; References;
Chapter 7: Arterial Anatomy for Prostatic Artery Embolization; Introduction; Internal Iliac Artery Anatomy; Prostatic Artery Origin Classification; Conclusion; References; Bibliography;
Chapter 8: Patient Selection for Prostatic Artery Embolization; Introduction; Symptom Evaluation; Prostatic Medication History; Prostate Anatomy; Cystoscopy; Uroflowmetry Testing; Comorbid Conditions