BookNicholas A. Tritos, Anne Klibanski, editors.
Contents:
Intro; Series Editor Foreword; Preface; Contents; Contributors;
Chapter 1: History of Prolactin Disorders; Medical Therapy; Introduction; Did Mary Tudor of England Have a Prolactinoma? [1]; The Discovery of Human Prolactin; Cell of Origin; Prolactin Action; Neuroendocrine Regulation; Actions of High Levels of Prolactin; Medical Treatment of Hyperprolactinaemia; Pituitary Tumour Shrinkage; Surgery; Radiotherapy; Summary; References;
Chapter 2: Pituitary Anatomy and Development; Historical Anatomy; Macroscopic Anatomy; Landmarks of the Sellar Region; Pituitary Gland Vascularization of the Pituitary GlandEmbryologic Anatomy; Radiologic Anatomy; Microscopic and Functional Anatomy; Anterior Pituitary (Adenohypophysis); Pars Distalis; Pars Intermedia; Marginal Zone; Pars Tuberalis; Posterior Pituitary; Concluding Remarks; References;
Chapter 3: Prolactin Assays and Regulation of Secretion: Animal and Human Data; Prolactin Assays; What Is Measured in Prolactin Assays?; The History of Prolactin Assays; Measurement of Prolactin Levels; Analytical Pitfalls; The "Hook Effect"; Macroprolactin; Interference from Heterophilic Antibodies; Interference with Biotin
Chapter 4: Physiological Actions and ReceptorsPhysiological Actions in Humans and Other Mammals; Mammary Glands; Reproductive Tissues; Receptors and Signaling; Conclusions; References;
Chapter 5: Prolactin Excess and Deficiency: Epidemiology, Causes (Excluding Prolactin-Secreting Pituitary Tumors); Introduction; Normal Levels of Prolactin; Prolactin Excess: Epidemiology and Causes; Physiologic Causes; Pregnancy; Nipple Stimulation and Lactation; Stress; Other; Pathologic Causes; Decreased Dopaminergic Inhibition of Prolactin Secretion; Decreased Clearance of Prolactin Prolactin Increase Due to Neural MechanismGenetic Causes: Germline Loss-of-Function Mutation; Other Causes; Pharmacological Causes; Antipsychotics; Antidepressants; Gastric Motility Drugs; Antihypertensive Drugs; Estrogens; Opioids; Other Drugs; Idiopathic Hyperprolactinemia; Prolactin Deficiency: Epidemiology and Causes; Pathological Causes; Sheehan's Syndrome; Genetic Causes; Pharmacological; Dopamine Agonists; Aripiprazole; Conclusion; References;
Chapter 6: Prolactin-Secreting Pituitary Adenomas: Epidemiology and Natural History; Epidemiology of Sporadic Prolactinomas; Population Studies