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  • Book
    Vinood B. Patel, Victor R. Preedy, editors.
    Summary: This multivolume reference work addresses the fact that the well being of humankind is predicated not only on individuals receiving adequate nutrition but also on their genetic makeup. The work includes more than 100 chapters organized in the following major sections: Introduction and Overview; Epigenetics of Organs and Diseases in Relation to Diet and Nutrition; Detailed Processes in Epigenetics of Diet and Nutrition; Modulating Epigenetics with Diet and Nutrition; and Practical Techniques. While it is well known that genes may encode proteins responsible for structural and dynamic components, there is an increasing body of evidence to suggest that nutrition itself may alter the way in which genes are expressed via the process of epigenetics. This is where chemically imposed alteration in the DNA sequence occurs or where the functional expression of DNA is modulated. This may include changes in DNA methylation, non-coding RNA, chromatin, histone acetylation or methylation, and genomic imprinting. Knowledge regarding the number of dietary components that impact on epigenetic processes is increasing almost daily. Marshalling all the information on the complex relationships between diet, nutrition, and epigenetic processes is somewhat difficult due to the wide myriad of material. It is for this reason that the present work has been compiled.

    Contents:
    Nervous system
    Development and ageing
    Cancers
    Caloric and dietary restriction
    Detailed processes in epigenetics of diet and nutrition.-Modifications of DNA via methylation
    Modifications of histones
    Modifications of non-coding RNAs
    DNA repair
    Modulating epigenetics with diet and nutrition
    General treatments and strategies
    Vitamins
    Minerals
    Specific foods and nutrients
    Nutritional toxicology
    Practical techniques.
    Digital Access Springer 2019