BookDavid P. Clark, Nanette J. Pazdernik, Michelle R. McGehee.
Summary: "Molecular Biology, Third Edition, provides a thoroughly revised, invaluable resource for college and university students in the life sciences, medicine and related fields. This esteemed text continues to meet the needs of students and professors by offering new chapters on RNA, genome defense, and epigenetics, along with expanded coverage of RNAi, CRISPR, and more ensuring topical content for a new class of students. This volume effectively introduces basic concepts that are followed by more specific applications as the text evolves"--Publisher's description.
Contents:
Unit 1: Basic chemical and biological principles. Cells and organisms
Basic genetics
DNA, RNA, and protein
Genes, genomes, and DNA
Manipulation of nucleic acids
Unit 2: The genome. The polymerase chain reaction
Cloning genes for analysis
DNA sequencing
Genomics and systems biology
New chapter to cover metagenomics, symbiosis, epigenomics etc
Unit 3: The central dogma of molecular biology. Cell division and DNA replication
Transcription of genes
Protein synthesis
Protein structure and function
Proteomics: global analysis of proteins
Unit 4: Regulating gene expression. Regulation of transcription in prokaryotes
Regulation of transcription in eukaryotes
Processing of RNA
Regulation at the RNA level
Genome defense (RNAi and CRISPR)
Analysis of gene expression (transcriptome)
Unit 5: Subcellular life forms. Plasmids
Viruses
Mobile DNA
Unit 6: Changing the DNA blueprint. Mutations and repair
Recombination
Bacterial genetics
Molecular evolution.