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  • Book
    Linqi Zhang, Sharon R. Lewin, editors.
    Summary: "This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry"--Publisher's description.

    Contents:
    HIV vaccines. HIV vaccine efficacy trials: RV144 and beyond / Elizabeth Heger, Alexandra Schuetz, Sandhya Vasan
    HIV T-cell vaccines / Beatriz Mothe, Christian Brander
    HIV broadly neutralizing antibodies: VRC01 and beyond / Xueling Wu
    Structural features of broadly neutralizing antibodies and rational design of vaccine / Tongqing Zhou, Kai Xu
    Monkey models and HIV vaccine research / Zhiwei Chen
    Treatment of HIV for the prevention of transmission in discordant couples and at the population level / M. Kumi Smith, Britta L. Jewell, Timothy B. Hallett, Myron S. Cohen
    HIV cure. HIV persistence on antiretroviral therapy and barriers to a cure / Julia Marsh Sung, David M. Margolis
    The molecular biology of HIV latency / Georges Khoury, Gilles Darcis, Michelle Y. Lee, Sophie Bouchat, Benoit Van Driessche, Damian F. J. Purcell [and others]
    Cellular determinants of HIV persistence on antiretroviral therapy / Anastassia Mikhailova, Jose Carlos Valle-Casuso, Asier Sáez-Cirión
    In vitro and in vivo models of HIV latency / James B. Whitney, R. Brad Jones
    Measuring HIV persistence on antiretroviral therapy / Bethany A. Horsburgh, Sarah Palmer
    Clinical interventions in HIV cure research / Thomas Aagaard Rasmussen, Ole S. Søgaard.
    Digital Access Springer 2018
  • Book
    CINVE, Centro de Investigaciones Económicas.
    Print [1985]
  • Article
    Barsel' VA, Dul'kin LM, Demidov AT.
    Vopr Onkol. 1977;23(11):50-6.
    Intravesical instillations of 10% dibunol liniment were used for the treatment of 132 patients with bladder tumors. An objective improvement was noted in 62.4%, including considerable lessening of the tumor size in 20% and its disappearance in 8.8% of patients. An efficacy of the treatment was considerably greater in bladder cancer in stages T1--T2 than in stages T3 and T4. The frequency of bladder cancer recurrence is found to be lowered following surgery associated with application of dibunol, also the manifest antiinflammatory activity of the drug is emphasized. No side effects relative to the toxic action of dibunol were observed. The use of dibunol seems to be rational in patients with bladder tumors of early stages, especially if associated with surgical therapy, and in tumor recurrences, and also with the symptomatic purposes in inoperable patients.
    Digital Access Access Options