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  • Book
    Karl L. Mettinger, Pranela Rameshwar, Vinod Kumar, editors.
    Summary: "This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular functions and begin repair regeneration. These early studies in animal models of aging also show evidence of improved immune, cardiovascular and cognitive functions as well as improved health span and life span. The use of exosomes from body fluids to define specific biomarkers for various tumors may also clear the path to patient-targeted treatments by developing exosome-derived microRNA based cancer therapeutics. It is essential reading for graduate students, research fellow and biomedical researchers in academia or the pharmaceutical or biotech industries"--Publisher's description.

    Contents:
    Part I. A new stem cell biology: transplantation and baseline, cell cycle and exosomes / Peter Quesenberry, Laura R. Goldberg
    The emerging roles of microRNAs in stem cell aging / Catharine Dietrich, Manish Singh, Nishant Kumar, Shree Ram Singh
    Part II. Treating age-related diseases with somatic stem cells / Robert W. Brooks, Paul D. Robbins
    Targeting miRNA for therapy of juvenile and adult diabetic cardiomyopathy / Shyam Sundar Nandi, Paras Kumar Mishra
    Stem cell therapies for neurodegenerative diseases / Kiminobu Sugaya, Manjusha Vaidya
    Part III. MicroRNAs, regulatory messengers inside and outside cancer cells / Simone Anfossi, Xiao Fu, Rahul Nagvekar, George A. Calin
    Exosomes function in tumor immune microenvironment / Yin Huang, Keli Liu, Qing Li, Yikun Yao, Ying Wang
    EV, microvesicles/microRNAs and stem cells in cancer / Jacob A. Tickner, Derek J. Richard, Kenneth J. O'Byrne
    Human aging and cancer: role of miRNA in tumor microenvironment / Oleta A. Sandiford [and others].
    Digital Access Springer 2018
  • Book
    Home Office.
    Summary: Voluntary bodies vary from tiny local groups to major charities and government funding of the voluntary sector has steadily risen over the last decade. In 1988/89, it amounted to #2.1 billion. This scrutiny was established to examine purposes for funding, types of funding and the procedures followed by government departments to ensure that the government is obtaining value for money. Nielsen 9780113409785 20160527
    Print 1990
  • Article
    Frisk CS, Wagner JE.
    Am J Vet Res. 1977 Nov;38(11):1861-8.
    Hamster enteritis (HE) was experimentally produced in weanling hamsters by orally inoculating healthy hamsters with suspensions of ilea obtained from hamsters with HE. Control groups of hamsters were inoculated orally with suspensions of ilea from healthy hamsters. Electron microscopy was done on ilea from 6 control hamsters, 31 hamsters with experimentally produced HE, and 4 hamsters with naturally occurring HE. Ultrastructural changes were not observed in the absorptive epithelium of control animals. Two different intracytoplasmic bacterial organisms were observed in epithelial cells of hamsters with experimentally produced HE. Organisms that were observed early in the disease process were identified as Escherichia coli. Organisms ultrastructurally similar to Campylobacter spp were observed later in the disease and were only within hyperplastic epithelial cells. The hyperplastic ileal epithelium of hamsters with naturally occurring HE contained campylobacter-like organisms.
    Digital Access Access Options