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  • Book
    Matthew Pitt.
    Summary: Paediatric Electromyography is a single-author textbook which covers the full range of applications of the techniques of nerve conduction and electromyography (EMG) in children from the neonatal period to the late teenage years. It comprises five sections. Section 1 in its first chapter, gives a detailed introduction to the different skills that are needed to effect successful interventions in paediatric EMG. The emphasis here is that paediatric EMG is not simply adult EMG applied to younger subjects.

    Contents:
    Introduction
    Basic physiology
    Nerve physiology
    Pathophysiological correlations in neuropathies
    Nerve damage and entrapment syndromes
    Motor unit anatomy and physiology
    Needle EMG findings in different pathologies
    Investigation of channelopathies
    Techniques used to test the neuromuscular junction in children
    Pthophysiological associations in paediatric neuromuscular junction disorders
    Results of the clinical application of SPACE in suspected disorders of the neuromuscular junction
    More advanced techniques.
    Digital Access Oxford 2018
  • Article
    Petes TD, Botstein D.
    Proc Natl Acad Sci U S A. 1977 Nov;74(11):5091-5.
    A diploid strain of yeast (Saccharomyces cerevisiae) was found to be heterozygous for two forms of the highly repetitious ribosomal DNA. These forms could be distinguished by the pattern of fragments produced after digestion with the site-specific restriction endonuclease EcoRI. The mode of inheritance of ribosomal DNA was determined by tetrad analysis. Of 14 tetrads analyzed, 12 clearly showed the ribosomal DNA forms segregating as a single Mendelian unit. The simplest interpretation of this result is that all of the approximately 100 copies of the ribosomal DNA genes of the yeast cell are located on one chromosome and that meiotic recombination within these genes is suppressed. Two of the 14 tetrads showed the segregation patterns expected as the result of mitotic recombination within the ribosomal DNA.
    Digital Access Access Options