BookGaetano Santulli, editor ; foreword by Wilson S. Colucci.
Summary: "This text covers the basic principles of mitochondrial dynamics in cardiovascular medicine, with particular emphasis on their functional roles in physiology and disease. The book will include articles pertaining to mitochondrial fitness on a global basis, providing therefore an update on the progress made in several aspects in the field. Thus, it will assist scientists and clinicians alike in furthering basic and translational research. Organized in sections focusing on: basic science, mitochondrial dysfunction in cardiac disorders, in vascular disorders, in metabolic disorders, in kidney disease, therapeutic challenges and options, this essential volume fills imperative gaps in understanding and potentially treating several cardiovascular disorders"--Publisher's description.
Contents:
Functional implications of cardiac mitochondria clustering / Felix T. Kurz, Miguel A. Aon, Brian O'Rourke, Antonis A. Armoundas
Mitochondrial calcium handling in physiology and disease / Veronica Granatiero, Diego De Stefani, Rosario Rizzuto
The in vivo biology of the mitochondrial calcium uniporter / Julia C. Liu, Randi J. Parks, Jie Liu, Justin Stares, Ilsa I. Rovira, Elizabeth Murphy [and others]
Mitochondrial bioenergetics and dysfunction in failing heart / Freya L. Sheeran, Salvatore Pepe
Mitochondrial mutations in cardiac disorders / Sung Ryul Lee, Jin Han
Mitochondrial function in non-ischemic heart failure / Anisha A. Gupte, Dale J. Hamilton, FACP
Mitochondria in ischemic heart disease / L. Maximilian Buja
Mitochondrial bioenergetics during ischemia and reperfusion / Alicia E. Consolini, Mar̕a I. Ragone, Patricia Bonazzola, Germ̀n A. Colareda
Mechanistic role of mPTP in ischemia-reperfusion injury / Giampaolo Morciano, Massimo Bonora, Gianluca Campo, Giorgio Aquila, Paola Rizzo [and others]
Functional role of mitochondria in arrhythmogenesis / Jessica Gambardella, Daniela Sorriento, Michele Ciccarelli, Carmine Del Giudice [and others]
Mitochondria and cardiac hypertrophy / Heberty di Tarso Fernandes Facundo, Robert Eli Brainard [and others]
Connexin 43 and mitochondria in cardiovascular health and disease / Kerstin Boengler, Rainer Schulz
Mitochondrial mechanosensor microdomains in cardiovascular disorders / Michele Miragoli, Aderville Cabassi
Mechanistic role of thioredoxin 2 in heart failure / Chaofei Chen, Haixuan Chen, Huanjiao Jenny Zhou, Weidong Ji, Wang Min
Mitochondria in structural and functional cardiac remodeling / Natalia Torrealba, Pablo Aranguiz, Camila Alonso, Beverly A. Rothermel [and others]
Functional role of Nox4 in autophagy / Maurizio Forte, Silvia Palmerio MS, Derek Yee, Giacomo Frati [and others]
Mitochondrial ubiquitin ligase in cardiovascular disorders / Tao Yu, Yinfeng Zhang, Pei-feng Li
Nitrite-nitric oxide signaling and cardioprotection / Matthias Totzeck, Ulrike B. Hendgen-Cotta, Tienush Rassaf
Peripheral blood mitochondrial dna and myocardial function / Tatiana Kuznetsova, Judita Knez
Mitochondrial proton leak plays a critical role in pathogenesis of cardiovascular diseases / Jiali Cheng, Gayani Nanayakkara, Ying Shao, Ramon Cueto, Luqiao Wang, William Y. Yang [and others]
Mitochondria and angiogenesis / Raluca Marcu, Ying Zheng, Brian J. Hawkins
High-density lipoprotein regulation of mitochondrial function / C. Roger White, Geeta Datta, Samantha Giordano
Mitomirs keep the heart beating / Samarjit Das, Hannah R. Vasanthi, Ramesh Parjapath
Mitochondrial dysfunction in cardiovascular aging / Charles L. Hoppel, Edward J. Lesnefsky, Qun Chen, Bernard Tandler
Insulin resistance and mitochondrial dysfunction / Alba Gonzalez-Franquesa, Mary-Elizabeth Patti
Mechanistic role of kinases in the regulation of mitochondrial fitness / Daniela Sorriento, Jessica Gambardella, Antonella Fiordelisi, Bruno Trimarco [and others]
Mitochondria damage and kidney disease / Pu Duann, Pei-Hui Lin
Mitochondrial dysfunction in the diabetic kidney / Kumar Sharma
Prohibitin signaling at the kidney filtration barrier / Christina Ising, Paul T. Brinkkoetter
Mitochondrial heteroplasmy / George B. Stefano, Christina Bjenning, Fuzhou Wang, Nan Wang [and others]
Mitochondrial transplantation in myocardial ischemia and reperfusion injury / Borami Shin, Douglas B. Cowan, Sitaram M. Emani, Pedro J. del Nido [and others]
Mitochondria-targeted antioxidants for the treatment of cardiovascular disorders / Hyoung Kyu Kim, Jin Han.