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  • Book
    Walter K.H. Krause, Rajesh K. Naz, editors.
    Summary: This book offers comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has four sections focusing on Sperm antigens, Antisperm antibodies (ASAs), Clinical impact of ASAs, and Immune contraception, and include contributions from leading experts in these fields. This new edition of the book offers a comprehensive update that reflects the very significant advances in reproductive immunology that have been achieved over the past five years, especially related to the sperm proteome, sperm-egg binding/fusion proteins, gene knockout studies, and immunocontraception. Reproductive immunology continues to be a fast-growing discipline in which new knowledge is emerging almost every day. Immune Infertility is a model source of vital and reliable information on the latest scientific developments in the field. It will be of value for clinicians, scientists, students, residents, and fellows working in reproductive biology, obstetrics and gynecology, and urology.

    Part I Sperm antigens: Proteomics of spermatozoa
    Sperm surface proteome
    Methods of Analysis of Sperm Antigens Related to Fertility
    Sperm functions influenced by immune reactions
    Part II Antisperm antibodies (ASA): The immune privilege of the testis
    Immune chemistry of ASA
    Sperm-specific T cells
    Site and risk factors of ASA production
    Biologic substrates containing ASA
    ASA in the female
    Sperm immobilising ASA
    Part III The clinical impact of sperm antibodies: Autoimmune infertility
    Tests for sperm antibodies
    Impact on fertility outcome
    Sperm antibodies and assisted reproduction
    Treatment of immune infertility
    Part IV Immune contraception: Immunization with Sperm Antigens to Induce Contraception
    Immune contraception in wildlife animals
    Experience from Clinical Trials with Fertility Control Vaccines.
    Digital Access Springer 2017